Expression of acyl-CoA-binding protein 5 from Rhodnius prolixus and its inhibition by RNA interference. by Muriel G M D Almeida, Daniela S Arêdes, David Majerowicz, Nils J Færgeman, Jens Knudsen, Katia C Gondim

“…In this study we investigated the expression and function of RpACBP-5. Feeding induced RpACBP-5 gene expression in the posterior midgut, and an increase of about four times was observed two days after the blood meal. …”
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New possibilities of phytotherapy in the treatment of urinary tract infections by S. V. Kotov, A. A. Nemenov, I. D. Boeva

“…A decrease in the titer of the pathogen and the growth rate of pathogenic microflora, according to urine culture, was observed in treatment group. The specific phytotherapy in the composition of complex therapy allows you to effectively cope with the inflammatory process, as well as reduce the frequency of recurrence of urinary tract infections.…”
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Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance. by Ashley Houlden, Kelly S Hayes, Allison J Bancroft, John J Worthington, Ping Wang, Richard K Grencis, Ian S Roberts

“…Changes in microbial composition occurred between 14 and 28 days post infection, resulting in significant changes in α and β- diversity. …”
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Time dependent genetic analysis links field and controlled environment phenotypes in the model C4 grass Setaria. by Max J Feldman, Rachel E Paul, Darshi Banan, Jennifer F Barrett, Jose Sebastian, Muh-Ching Yee, Hui Jiang, Alexander E Lipka, Thomas P Brutnell, José R Dinneny, Andrew D B Leakey, Ivan Baxter

“…The results support a model where plant height is a heritable, polygenic trait and that the major genetic loci that influence plant height function independent of growth environment. The identity and contribution of loci that influence height changes dynamically throughout development and the reduction of growth observed in water limited environments is a consequence of delayed progression through the genetic program which establishes plant height in Setaria. …”
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Comparative analysis of organic fertilizers of different origins by Galaktionova Lyudmila

“…The results of the study of the chemical composition of humic fertilizers showed their similar mineral composition with a predominance of K, Si, Cl, Cu and Ca. …”
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Vaping – A Beneficial Alternative to Traditional Cigarettes or an Unexplored Danger? by Paulina Błasiak, Aleksandra Ślusarska, Patryk Mikołajec, Barbara Bilecka, Jolanta Mędyk, Małgorzata Wirkijowska, Jakub Wirkijowski, Yauheniya Patarocha, Michał Rogulski, Ruslan Huk

“…Conclusions:  The precise impact of e-cigarette use on health needs further research and long-term observations. Particular concern arises from the unregulated composition of e-liquids, which are gaining popularity among youth, thereby promoting early nicotine addiction and normalizing the use of tobacco products. …”
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Postbiotics Regulate Intestinal Microbiota and Reduce Amyloid β-Protein Deposition in the Brain, Thereby Ameliorating Cognitive Impairment in Rats with Alzheimer’s Disease by XIAO Ling, TANG Linlin, SONG Xiaoyan, ZHANG Yihua, HAN Xuemei, LÜ Houjiao, LIANG Wu, WANG Yanping, GENG Weitao, JIA Longgang

“…Thus, the postbiotics IOBL07, IOB602, and IOB413 have significant efficacy in ameliorating memory and cognitive deficits in AD rats, the most pronounced effect being observed with high-dose IOB602. The underlying mechanisms might be associated with regulating the structure and composition of the gut microbiota and down-regulating the relative mRNA transcription levels of TLR4, NLRP3 and MyD88 in brain tissues.…”
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ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity by Shihan Zhou, Shangbo Hua, Xinyi Chen, Meiling Ni, Jing Liu, Yanqing Wang, Wanning Wu, Anni Ding, Zizhen Qin, Xinyu Yang, Xiaowei Chen, Boran Zhu, Haoxin Wu

“…Additionally, there was an enhancement observed in the expression of tight junction proteins within the intestinal tissue of AS mice. …”
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Analysis of covalent adaptable networks Based on disulfide exchange through broadband dielectric spectroscopy by B. Pascual-Jose, R. Teruel-Juanes, S. de la Flor, A. Serra, A. Ribes-Greus

“…In the DGEBA/HMDA-CYS membrane, its relaxation function and activation energy are between those corresponding to the DGEBA/HDMA and DGEBA/CYS membranes, but their relationship does not depend linearly on the composition. …”
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Investigation of Blood Supply to the Macular Region of the Retina in Chronic Myeloproliferative Diseases by E. M. Yunusova, T. R. Mukhamadeev, B. A. Bakirov, G. M. Idrisova

“…With CMPD changes in the composition of peripheral blood are observed, leading to changes in the rheology of blood and contributing to the deterioration of microcirculation of eye tissues. …”
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Novel glycopolymer sensitizes Burkholderia cepacia complex isolates from cystic fibrosis patients to tobramycin and meropenem. by Vidya P Narayanaswamy, Scott Giatpaiboon, Shenda M Baker, William P Wiesmann, John J LiPuma, Stacy M Townsend

“…During treatment, PAAG rapidly targets the anionic structural composition of bacterial outer membranes. PAAG was observed to permeabilize bacterial membranes upon contact to facilitate potentiation of antibiotic activity. …”
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Environmental drivers of the resistome across the Baltic Sea by Joeselle M. Serrana, Francisco J. A. Nascimento, Benoît Dessirier, Elias Broman, Malte Posselt

“…In this study, we characterized the environmental resistome of the Baltic Sea and evaluated how environmental gradients and spatial variability, alongside its microbial communities and associated functional genes, influence resistome diversity and composition across geographic regions. …”
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The Impact of Physical Activity on the Course of Inflammatory Bowel Diseases by Adam Grzebinoga, Julia Szlążek, Michalina Zagalska, Marta Turek, Adam Jan Ząbek, Jakub Paweł Kuźniar, Emilia Gabriela Chrzanowska, Barbara Roguska, Tomasz Tamborski

“…This review explores the multifaceted impact of PA on IBD, focusing on gut microbiota composition, intestinal barrier integrity, and immune function. …”
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Single-cell transcriptomic analyses reveal heterogeneity and key subsets associated with survival and response to PD-1 blockade in cervical squamous cell carcinoma by Xia Li, Zhao Zhao, Yanmei Cheng, Jiaqin Yan, Fang Ren, Yanyan Jia, Juanhua Li, Binhui Wang, Junqi Liu, Chenyin Wang, Meimei Gao, Hao Gu, Mingliang Fan, Huirong Shi, Mei Ji, Qitai Zhao

“…In vivo experiments were performed to validate the function of key cell subsets. Results We identified ten major cell type and 35 subsets of stromal and immune cells in TME and observed distinct patterns in the metabolic processes and signaling pathways of these cells between tumor and normal tissues. …”
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Cardiac Transplantation Does Not Improve Exercise Tolerance, Muscle Mass, or Substrate Metabolism in Barth Syndrome by W. Todd Cade, Kathryn L. Bohnert, Linda R. Peterson, Lisa de las Fuentes, Emily Poehlein, Cynthia L. Green, Christina A. Pacak, Barry J. Byrne, Dominic N. Reeds, Adil Bashir, Brian Feingold, Carolyn Taylor

“…While cardiac transplantation can improve heart function in BTHS patients, the metabolic effects of this procedure remain poorly understood. …”
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The gut microbial metabolite indole-3-aldehyde alleviates impaired intestinal development by promoting intestinal stem cell expansion in weaned piglets by Jiaqi Zhang, Yahui Chen, Xin Guo, Xuan Li, Ruofan Zhang, Mengting Wang, Weiyun Zhu, Kaifan Yu

“…Furthermore, we explored the effects of dietary indole-3-aldehyde (IAld), a key tryptophan metabolite, on intestinal development and gut barrier function in weaned piglets. Supplementation with 100 mg/kg IAld in the diet increased the small intestine index and improved intestinal barrier function by promoting intestinal stem cell (ISC) expansion in piglets. …”
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Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation by Kaidi Chen, Seongmin Ha, Leyao Xu, Chengwu Liu, Yuanxiang Liu, Xiayi Wu, Zhipeng Li, Shiyu Wu, Bo Yang, Zhuofan Chen

“…Methods FPHA was synthesized and its composition and structural properties were confirmed. …”
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Macrophages and the microbiome in chronic obstructive pulmonary disease by Karanjot K. Sandhu, Aaron Scott, Amanda L. Tatler, Kylie B.R. Belchamber, Michael J. Cox

“…In patients with COPD, there are distinct changes in the composition of the respiratory microbiome, particularly the lower respiratory tract, where dominance of clinically relevant pathogenic species is commonly observed. …”
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Differential Cell Death Pathways Induced by Oxidative Stress in Multi-Organs of Amur Grayling (<i>Thymallus grubii</i>) Under Gradient Ammonia Stress by Cunhua Zhai, Yutao Li, Ruoyu Wang, Ying Zhang, Bo Ma

“…Our results showed that excessive ammonia nitrogen blocked the normal immune function and compromised the integrity of liver and gill tissues through oxidative stress-mediated differential cell death pathways. …”
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Sex-specific differences in preclinical models of advanced chronic liver disease and portal hypertension by Peio Aristu-Zabalza, María Andrés-Rozas, Zoe Boyer-Díaz, David P. Al-Adra, Douglas Maya-Miles, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Jordi Gracia-Sancho

“…No differences were observed in hepatic microvascular function. In the BDL model, females had more fenestrae and porosity, and less fibrosis. …”
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