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1961
Rational computational design and development of an immunogenic multiepitope vaccine incorporating transmembrane proteins of Fusobacterium necrophorum
Published 2025-05-01“…Molecular dynamics simulations confirmed structural stability and receptor engagement. The RMSD stabilized around 4–5 Å, indicating structural stability of the Vaccine-TLR8(B) complex. …”
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1962
Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu...
Published 2025-01-01“…In addition, the individual residue contribution analysis highlighted key interactions, with ARG149 showing a significant contribution (-176.24 kcal/mol) in the MLKL-SG-A complex. …”
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1963
Multisource Heterogeneous Sensor Processing Meets Distribution Networks: Brief Review and Potential Directions
Published 2025-07-01“…Based on the characteristics of DN data, e.g., diverse sources, heterogeneous structures, and complex correlations, this article proposes several practical future directions. …”
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1964
LTR-Net: A deep learning-based approach for financial data prediction and risk evaluation in enterprises.
Published 2025-01-01“…Financial data prediction and risk assessment represent a complex multi-task problem that requires effective handling of time-series data and multi-dimensional features. …”
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1965
Potential Azo-8-hydroxyquinoline derivatives as multi-target lead candidates for Alzheimer's disease: An in-depth in silico study of monoamine oxidase and cholinesterase inhibitors...
Published 2025-01-01“…Cognitive dysfunction in Alzheimer's disease results from a complex interplay of various pathological processes, including the dysregulation of key enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and monoamine oxidase B (MAO-B). …”
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1966
Microwave absorption behaviour of MWCNT based nanocomposites in X-band region
Published 2013-03-01“…Incorporation of MWCNT enhanced the thermal stability of the composite which has been confirmed by thermogravimetric analysis.…”
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1967
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1968
Exploration of effective pharmacological inhibitors for NS5 protein through computational approach: A strategy to combat the neglected Kyasanur forest disease virus.
Published 2025-01-01“…MD simulations in triplicates under physiological conditions confirmed stability. with MM-GBSA binding free energy values of -52.28 ± 2.91 kcal/mol (NS5-Dasabuvur L1complex), -46.82 ± 4.31 kcal/mol (NS5-L2 complex), -50.72 ± 6.36 kcal/mol (NS5-L3 complex), and -57.03 ± 4.31 kcal/mol (NS5-L4 complex). …”
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1969
Exploring geodesics, quantum fields and thermodynamics of Schwarzschild-AdS black hole with a global monopole in non-commutative geometry
Published 2025-08-01“…By employing the eikonal approximation, we compute the complex quasinormal mode (QNM) frequencies and analyze how their real and imaginary parts evolve with changes in the underlying parameters. …”
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1970
Impacts of wildfire smoke aerosols on radiation, clouds, precipitation, climate, and air quality
Published 2025-04-01“…Developing more robust adaptation strategies and resilience measures is essential to effectively mitigate these complex, adverse effects on communities and the environment.…”
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1971
Robust Wide-Speed-Range Control of IPMSM with Multi-Axis Coordinated Extended State Observer for Dynamic Performance Enhancement
Published 2025-06-01“…Subsequently, the effectiveness and stability of the proposed method were verified through theoretical analysis and simulation studies. …”
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1972
ESTIMATION OF THE DEPTH OF ANESTHESIA BY ELECTROENCEPHALOGRAM USING NEURAL NETWORKS
Published 2019-07-01“…Monitoring of the depth of anesthesia during surgery is a complex task. Since electroencephalogram (EEG) signals contain valuable information about processes in the brain, EEG analysis is considered to be one of the most useful methods for study and assessment of the depth of anesthesia in clinical applications. …”
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1973
The Application of Molecularly Imprinted Polymers in Forensic Toxicology: Issues and Perspectives
Published 2024-12-01“…Despite advantages like reusability and high selectivity, MIPs face limitations in forensic analysis due to their complex synthesis, potential template leakage, and non-specific binding. …”
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1974
ECG Signal Classification Using Interpretable KAN: Towards Predictive Diagnosis of Arrhythmias
Published 2025-02-01“…Additionally, convergence analysis reveals that the KAN’s training process exhibits a smooth and stable loss decline curve, confirming its robustness under complex data conditions. …”
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1975
In silico identification of novel ligands targeting stress-related human FKBP5 protein in mental disorders.
Published 2025-01-01“…Molecular dynamic (MD) simulation validated strong interactions between our three key ligands and FKBP5 protein and provided an understanding of the stability of the complex. The binding free energy (ΔG) of the best ligands (based on pharmacological properties) from MD simulation analysis is -31.78 kcal/mol for neoruscogenin, -30.41 kcal/mol for ruscogenin, and -27.6 kcal/mol for curcumin. …”
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1976
Research on the application of a model combining improved optimization algorithms and neural networks in trajectory tracking of robotic arms
Published 2025-08-01“…This model has shown higher accuracy and lower tracking errors when handling complex nonlinear systems. These advantages suggest that the MMGO has broader applicability and higher reliability in practical applications. …”
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1977
Enhancing organisational resilience through systems thinking
Published 2025-01-01“…In the face of complex challenges driven by technological advancements and global crises, organisations must develop better strategies for survival and sustainability. …”
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1978
An Optimized GWO-BPNN Model for Predicting Corrosion Fatigue Performance of Stay Cables in Coastal Environments
Published 2024-12-01“…The GWO-BPNN model excels in capturing complex, non-linear dependencies within fatigue data, outperforming conventional prediction methods. …”
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1979
Towards Efficiency and Endurance: Energy–Aerodynamic Co-Optimization for Solar-Powered Micro Air Vehicles
Published 2025-07-01“…Wind tunnel validation and stability analysis of flight dynamics confirm the advantages of our optimized design. …”
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1980
An improved enterprise development optimizer based on labor migration for numerical optimization
Published 2025-07-01“…These shortcomings restrict the performance of the algorithm in some complex problem. This research proposes an improved EDO, called LMEDO, in which EDO is integrated with incorporates time-phase based switching strategy, economy-driven guided based learning strategy and spatial selectivity-based selection strategy to improve convergence rate, stability, and search effectiveness. …”
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