Repurposing terfenadine and domperidone for inhibition of apoptotic gene association in colorectal cancer: A system pharmacology approach integrated with molecular docking, MD simu... by Pushpaveni C, Hemavathi S, Santosh Prasad Chaudhary Kurmi, Biswa Ranjan Patra, V Angelin Esther, Chandrajeet Kumar Yadav, Mahalakshmi Suresha Biradar, Shankar Thapa

“…Furthermore, post-MD simulation study supports the stable score landscape and stability of complex. In conclusion, this integrative computational analysis highlights terfenadine and domperidone as promising candidates capable of modulating key apoptotic pathways in CRC. …”
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Engineering behavior and geotechnical challenges of sulfate-rich soils in Astana by Nazerke Sagidullina, Alfrendo Satyanaga, Jong Kim, Sung-Woo Moon

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High‐Entropy Non‐Flammable Ionic Liquid/Dimethoxymethane Composite Electrolyte for High‐Performance Lithium‐Ion Batteries by Purna Chandra Rath, Chun‐Yen Chen, Jagabandhu Patra, Chun‐Chen Yang, Yu‐Sheng Su, Chien‐Te Hsieh, Wei‐Ren Liu, Ju Li, Jeng‐Kuei Chang

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Evaluating Directed Acyclic Graphs with DAGMetrics: Insights from Tuber and Soil Microbiome Data by Pavel Averin, Ifigeneia Mellidou, Maria Ganopoulou, Aliki Xanthopoulou, Theodoros Moysiadis

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Condition monitoring of heterogeneous landslide deformation in spatio-temporal domain using advanced graph attention network by Huajin Li, Yu Zhu, Qiang Xu, Ran Tang, Chuanhao Pu, Yusen He

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Custom 3D-printed porous titanium augments for Paprosky type III acetabular defects: a case series combining biomechanical rationale with early clinical outcomes by Tengbin Shi, Wenming Zhang, Xinyu Fang

“…Finite element analysis (FEA) simulated the defects, utilizing a commercial augment as a control. …”
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Exploring Socioeconomic Challenges Using Latent Dirichlet Allocation and Text Mining: Convergence Points Between World Bank and The International Monetary Fund Reports by Yasmine Derradj, Rachid Toumache

“…The study underscores the effectiveness of structured text-mining methodologies in analyzing economic discourse and institutional viewpoints, demonstrating their value in capturing complex economic themes. By systematically identifying thematic coherence, this research contributes to economic policy formulation and financial stability in resource-dependent economies. …”
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Temperature sensitivity of the interspecific interaction strength of coastal marine fish communities by Masayuki Ushio, Testuya Sado, Takehiko Fukuchi, Sachia Sasano, Reiji Masuda, Yutaka Osada, Masaki Miya

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Sustainable additive manufacturing of recycled RPU/PLA composites via filament extrusion for enhanced mechanical and acoustic properties by Vinoth Kumar Selvaraj, Jeyanthi Subramanian, Ravi Seenivasan, B․G Sai Charan, Bhaherathi S, Aachal Vinayak Kulkarni, Vinod Ayyappan, Sanjay Mavinkere Rangappa, Suchart Siengchin

“…High-resolution scanning electron microscopy (HR-SEM), thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) provided insights into the composite’s morphology, chemical interactions, and thermal stability. …”
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Deep behavioral phenotyping tracks functional recovery following tibia fracture in mice by Jonathan E. Layne, Dustin M. Snapper, Dustin M. Snapper, Molly E. Czachor, Charles Lam, Jacob D. Matityahu, Dane R. G. Lind, Matthieu Huard, Johnny Huard, Kazuhito Morioka, Julian C. Motzkin, Julian C. Motzkin, Allan I. Basbaum, Jarret A. P. Weinrich, Jarret A. P. Weinrich, Chelsea S. Bahney, Chelsea S. Bahney

“…By contrast, we observed only minor sex-specific differences in impairment and recovery following fracture. Our analysis revealed that functional recovery is more complex than individual parameters viewed in isolation, with different parameters identifying distinct recovery timeframes. …”
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Plasma Fatty Acid Profiling and Mathematical Estimation of the Omega-3 Index: Toward Diagnostic Tools in Atherosclerosis and Statin Therapy Monitoring by Nikolay Eroshchenko, Elena Danilova, Anastasiia Lomonosova, Alexey Antonik, Svetlana Lebedeva, Daria Gognieva, Dmitry Shchekochikhin, Tatiana Demura, Marina Krot, Nana Gogiberidze, Abram Syrkin, Philipp Kopylov

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Enhanced Hysteresis Droop Control for Equivalent Load Sharing in Parallel PWM DC-DC Converters: Optimized Slew Rate by Resonant Filtering by Cagfer Yanarates, Aytac Altan

“…The basis behind the work encompasses power system stability, reliability, efficiency, reduction of losses and decrease in the operational cost. …”
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An efficient space–time two-grid difference approach to symmetric regularized long waves: Enhanced efficiency and accuracy by Jingying Gao, Siriguleng He, Buhe Eerdun, Chunhui He, Jihuan He

“…Our conservation laws analysis is also deepened, with detailed numerical examples provided to showcase how the ST-TG scheme faithfully adheres to the conservation of mass, momentum, and energy, underpinning its stability and physical consistency. …”
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Computational molecular insights into ibrutinib as a potent inhibitor of HER2-L755S mutant in breast cancer: gene expression studies, virtual screening, docking, and molecular dyna... by Tamizhini Loganathan, C. George Priya Doss

“…MM-PBSA analysis revealed that the HER2-L755S-ibrutinib complex had more negative binding energy than the HER2-L755S-afatinib, HER2-L755S-lapatinib, and HER2-L755S-neratinib complexes, suggesting that ibrutinib forms the most stable complex with favorable binding interactions.ConclusionThese results provide in-depth atomic-level insights into the binding mechanisms of these inhibitors, highlighting ibrutinib as a potentially effective inhibitor for the clinical treatment of breast cancer.…”
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Multifractal Carbon Market Price Forecasting with Memory-Guided Adversarial Network by Na Li, Mingzhu Tang, Jingwen Deng, Liran Wei, Xinpeng Zhou

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Multi-Condition Magnetic Core Loss Prediction and Magnetic Component Performance Optimization Based on Improved Deep Forest by Haotian Shi, Zipeng Jin

“…Magnetic components play a crucial role in voltage stabilization, conversion, and filtering, conventional loss models struggle to accurately characterize the nonlinear loss characteristics under multi-physics coupling and complex operating conditions. …”
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Network pharmacology and in silico approaches to uncover multitargeted mechanism of action of Zingiber zerumbet rhizomes for the treatment of idiopathic pulmonary fibrosis [version... by Bharath Harohalli Byregowda, Usha Yogendra Nayak, Gayathri S, Krishnaprasad Baby, Yogendra Nayak, Swastika Maity, Shaik Mohammad Fayaz

“…Confirmational molecular docking and dynamics simulation studies possessed good stability and interactions of the protein-ligand complexes by RMSD, RMSF, rGyr, SASA, and principal component analysis (PCA). …”
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Combining temperature ramp dry combustion and mid-infrared spectroscopy for enhanced soil organic carbon characterisation by Lewis Walden, Raphael A. Viscarra Rossel

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Design, evaluation, cytotoxic activity, molecular docking, ADMET analysis, and dynamic simulations and the preparation of new isoxazoles, thiazoles, 1,3-thiazines, and thiazolopyri... by Ameen A. Abu-Hashem, Nasser Amri, Ahmed F. El-Sayed

“…Molecular dynamics simulations confirmed the stability of complexes formed by compounds 5d, 11a, and 11b with CDK2, ERα, VEGFR, and EGFR. …”
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Mechanism of nimodipine in treating neurodegenerative diseases: in silico target identification and molecular dynamic simulation by Shuang Zheng, Shuang Zheng, Shuang Zheng, Yin Wang, Shuainan Tang, Yuntao Guo, Duan Ma, Xin Jiang

“…Molecular docking was carried out using AutoDock Vina, and the ligand-receptor complexes with the highest binding affinities were further simulated using GROMACS to assess the dynamic structural stability and interactions between the ligand and receptor in the dynamic system.ResultsA total of 33 intersecting drug-disease targets were identified. …”
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