Screening helper T lymphocyte epitopes based on IFN-γ/IL-10 ratio for developing a novel multi-epitope vaccine candidate using Wolbachia surface protein as an adjuvant against visc... by Jianhui Zhang, Tianhang Lv, Shuoyan Tan, Lingqi Yu, Yangjian Chi, Jianping Chen, Xiaohui Fan, Xiaoyan Lu

“…Molecular docking and molecular dynamics simulations were carried out to analyze the interactions and stability of the docked complexes. The immune simulation of a multi-epitope vaccine candidate was carried out to predict its immunogenicity. …”
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Forecasting Macroeconomic Dynamics in Ukraine: The Impact of a Full-Scale War by Olena Dobrovolska, Olena Kolotilina, Mariia Ostapenko

“…The paper discusses the challenges and complexities of forecasting economic dynamics in conflict zones, where traditional economic models are insufficient to account for the uncertainties and shocks caused by conflict. …”
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Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas by Rebecca Schüle, Christine Dictus, Benito Campos, Feng Wan, Jörg Felsberg, Rezvan Ahmadi, Franz-Simon Centner, Niels Grabe, Guido Reifenberger, Justo L. Bermejo, Andreas Unterberg, Christel Herold-Mende

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Changing epidemiology of leptospirosis in China from 1955 to 2022 by Zengliang Wang, Ke Li, Yuanhua Liu, Michael P. Ward, Yue Chen, Shuting Li, Jidan Zhang, Yu Zhao, Na Wang, Haiyan Qiu, Yueran Lian, Cuicai Zhang, Zhijie Zhang, Biao Kan

“…The nearly 70-year dataset underscores the complex interplay of climate and socioeconomic factors influencing the disease’s occurrence. …”
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Study on the effects of extreme climate and human activities on the growth mechanisms of Zostera japonica in the Yellow River estuary by Yanning Gao, Yanning Gao, Yanning Gao, Kebing Chen, Kebing Chen, Zixuan Ma, Yujun Yi, Yujun Yi

“…This study investigates the complex effects of extreme climate events and human activities on the growth mechanisms of Zostera japonica in the Yellow River Estuary using a combination of field sampling, laboratory analysis, and quantitative calculations. …”
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Quantifying the impact of building layouts on wind–thermal environments: A computational fluid dynamics-based approach for optimizing plans and designs in high-temperature, low-win... by Junwen Li, Rongjie Jian, Shitai Bao, Qixin Pan, Darong Guo, Hui Gao

“…Similar trends were observed for length–width ratios of 2 and intervals above and below 4 m; 3) the four factors exhibited complex nonlinear relationships with the wind–thermal environment. …”
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MODERN METHODS OF DIAGNOSIS AND TREATMENT IN PATIENTS WITH DENTITION DEFECTS COMPLICATED OF DISORDERS OF THE TEMPOROMANDIBULAR JOINT by R. Ozhohan, M. Rozhko, Z. Ozhohan

“…After stabilization of the TMJ the permanent modern design of aesthetic metal-based or zirconium dioxide constructions were made. …”
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Impact of residential density on heavy metal mobilization in urban soils: Human activity patterns and eco-health risks in the Beijing-Tianjin-Hebei region by Siyu Wang, Lingqing Wang, Xiaoyong Liao, Guangjin Zhou, Yizhong Huan, Shun Li, Tao Liang

“…Specifically, Pb mobilization was driven by TOC-metal complexation, while Cu redistribution was linked to carbon-nitrogen interactions. …”
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Neurotensin(8-13) analogs targeting NTS1 and NTS2 receptors: A comparative in vitro and molecular modeling study by Kiril Kirilov, Maria Ponticelli, Toni Kühl, Harald Hübner, Maya G. Georgieva, Matthias Vogel, Aneliya A. Balacheva, Bodo Haas, Tamara I. Pajpanova, Maima Matin, Luigi Milella, Peter Gmeiner, Diana Imhof, Nikolay T. Tzvetkov

“…Furthermore, we applied an AI-based approach to generate the homology models of hNTS1R and hNTS2R, followed by MD simulations of their ligand-free state and molecular docking in order to estimate the most probable protein–ligand complexes of peptides 3 and 6. Binding interaction/affinity analysis of the best-ranked docking modes, obtained with selected time-frames from the respective MD trajectories, suggest that the receptor activation occurs via a ligand-receptor binding into the initial “entry” conformation of hNTS1R and hNTS2R. …”
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Biofertilizers Enhance Soil Fertility and Crop Yields Through Microbial Community Modulation by Xu Zhang, Lei Zhang, Junjie Liu, Zongzuan Shen, Zhuxiu Liu, Haidong Gu, Xiaojing Hu, Zhenhua Yu, Yansheng Li, Jian Jin, Guanghua Wang

“…Co-occurrence network analysis revealed that biofertilizers enhanced microbial network stability and complexity compared to conventional fertilization techniques. …”
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Robotic pedicle screw placement for minimal invasive thoracolumbar spine surgery: a technical note by Luthfi Gatam, Luthfi Gatam, Luthfi Gatam, Phedy Phedy, Phedy Phedy, Syafruddin Husin, Harmantya Mahadhipta, Asrafi Rizki Gatam, Asrafi Rizki Gatam, Asrafi Rizki Gatam, Mitchel Mitchel, Karina Sylvana Gani, Erica Kholinne, Erica Kholinne

“…It also covers the surgical process, including patient positioning, dynamic reference placement, intraoperative cone-beam tomography, screw planning, exposure, and insertion techniques for spinal stabilization.DiscussionA meta-analysis highlighted the significant advantages of robotic spine surgery over traditional freehand techniques, including a notably lower complication rate (4.83% vs. 14.97%) and up to a tenfold reduction in surgeon radiation exposure compared to fluoroscopy. …”
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TrypPROTACs Unlocking New Therapeutic Strategies for Chagas Disease by Ana Luísa Rodriguez Gini, Pamela Souza Tada da Cunha, Emílio Emílio João, Chung Man Chin, Jean Leandro dos Santos, Esteban Carlos Serra, Cauê Benito Scarim

“…Key aspects of linker engineering and ternary complex stabilization are discussed, alongside potential validation techniques such as the cellular thermal shift assay (CETSA) and bioluminescence resonance energy transfer (NanoBRET). …”
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Evaluation of the Mechanical Properties and Fatigue Resistance of the ZrO₂CeYAl₂O₃ Composite by Marcio Paulo de Araújo Mafra, Nélio Silva Júnior, Claudinei dos Santos, Jorge Luiz de Almeida Ferreira, José Alexander Araújo, Cosme Roberto Moreira da Silva

“…The sintered samples presented values above 98% of relative density. Complex microstructures with equiaxed, homogeneously distributed submicrometer grains and planar alumina platelets were observed by SEM. …”
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Trifluoromethoxy- and Fluorobenzhydryl-Tuned Nickel Catalysts for Polyethylene Elastomers by Ming Liu, Min Sun, Yanping Ma, Yizhou Wang, Mingfeng Li, Wen-Hua Sun

“…Upon activation with either EtAlCl₂ (ethylaluminum dichloride) or EASC (ethyl aluminum sesquichloride), these complexes showed exceptional high activities (up to 22.0 × 10⁶ g PE mol⁻¹ (Ni) h⁻¹) and remarkable thermal stability (4.82 × 10⁶ g PE mol⁻¹(Ni) h⁻¹ at 80 °C) towards ethylene polymerization. …”
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Investigation of Configurations of \begin{document}${ \left[{\bf{UO}}_{\bf{2}}({\bf{OH}})_{\boldsymbol{m}}({\bf{H}}_{\bf{2}}{\bf{O}})_{\boldsymbol{n}}\right]^{{\bf{2}}-{\boldsymbol... by Xiu-lin ZENG, Meng-ke TIAN, Shuang-ling TANG, Xue-hai JU

“…The increase of H2O ligand is beneficial to the stability of the complexes. The formations of [UO2(OH)m]2‒m (m＜4) are spontaneous processes. …”
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LEXICAL DESYNONYMY IN B. VIAN’S NOVEL “FROTH ON THE DAYDREAM” by Anastasiia V. Lepetiukha

“…Vian and the linguo-stylistic and interpretative analyzes in order to reveal and characterize the idiostylistic features of the author and to justify the co(n)textual pertinence of the distinguished lexical desynonyms. In the process of analysis of the novel “Froth on the Daydream” by B. …”
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Optimizing Load Frequency Control of Multi-Area Power Renewable and Thermal Systems Using Advanced Proportional–Integral–Derivative Controllers and Catch Fish Algorithm by Saleh A. Alnefaie, Abdulaziz Alkuhayli, Abdullah M. Al-Shaalan

“…In the complex dynamics of a two-area interconnected power system, the results show how robust the suggested CFA-tuned PI(1+DD) control strategy is and how well it can stabilize variations in load frequency and tie-line power with a noticeably shorter settling time. …”
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Pathophysiological substantiation of medical evacuation of the wounded persons, suffering injuries of the extremities on the levels of medical support by І. P. Khomenko, S. О. Коrol, B. V. Маtviychuk, L. А. Ustinova

“…Маterials and methods. Complex pathophysiologic investigation, concerning 378 wounded persons, suffering a combat traumas of the extremities in accordance to 26 indices of homeostasis, was conducted. …”
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Research on Fracture Energy Prediction and Size Effect of Concrete Based on Deep Learning with SHAP Interpretability Method by Huiming Wang, Weiqi Zhang, Jie Lin, Shengpin Guo

“…Moreover, owing to the complex nonlinear behavior exhibited by concrete during the fracturing process, existing empirical formulas exhibit restricted precision when forecasting fracture energy. …”
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Reconciling different interests in the Hutan Harapan rainforest ecosystem restoration management in Sumatra, Indonesia by Mangarah Silalahi, Dodik R. Nurrochmat, Rhett D. Harrison, Irdika Mansur, Thomas A. Walsh, Habibi

“…This study presents lessons from PT REKI's experience in the forest in addressing complex issues and threats with different management approaches. …”
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