The impact of interactions between heavy metals and smoking exposures on the formation of oral microbial communities by Qiwen Zheng, Yonghua Zhang, Jia Li, Shuwei Pei, Jiangyun Liu, Lu Feng, Li Zhang, Xingrong Liu, Bin Luo, Ye Ruan, Weigang Hu, Jingping Niu, Tian Tian

“…This exposure reduces the complexity and stability of microbial networks and increases the risk of various diseases reduces the complexity and stability.…”
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Structural basis of lipopolysaccharide translocon assembly mediated by the small lipoprotein LptM by Ryoji Miyazaki, Mai Kimoto, Hidetaka Kohga, Tomoya Tsukazaki

“…Cryoelectron microscopy structural analysis of the Escherichia coli LptDEM complex, combined with biochemical analyses, reveals the molecular basis of the LptM-LptD interaction and its functional importance. …”
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Deep learning based predictive modeling to screen natural compounds against TNF-alpha for the potential management of rheumatoid arthritis: Virtual screening to comprehensive in si... by Tasnia Nabi, Tanver Hasan Riyed, Akid Ornob

“…Later on, the stability of complexes was assessed via analysis encompassing RMSD, RMSF, Rg, H-Bonds, SASA, and Essential Dynamics. …”
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Variation in soil microbial networks and biogeochemical cycles in the Yalu river Estuary wetland by Yu Song, Ming Gao, Chunpeng Zhang, Guiwei Qu, Fuxiang Li

“…The bacterial network in bog soil exhibits greater stability, whereas the archaeal network in paddy soil demonstrates increased complexity. …”
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The antitumor mechanisms of glabridin and drug delivery strategies for enhancing its bioavailability by Chong Li, Yu Wang, Wenjing Zhang, Xiaoman Yang, Yufang Wang, Guanqun Hou, Dongli Wang, Bingbing Han, Yimin Zhang, Yimin Zhang

“…To enhance its solubility, stability, and bioavailability, several drug delivery systems have been developed, including liposomes, cyclodextrin inclusion complexes, nanoparticles, and polymeric micelles. …”
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Synthesis, Characterization, and Biological Activity Studies of Copper(II) Mixed Compound with Histamine and Nalidixic Acid by Egla Yareth Bivián-Castro, Mercedes G. López, Mario Pedraza-Reyes, Sylvain Bernès, Guillermo Mendoza-Díaz

“…A mixed copper complex with deprotonated nalidixic acid (nal) and histamine (hsm) was synthesized and characterized by FTIR, UV-Vis, elemental analysis, and conductivity. …”
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Trajectory optimization of a flapping-wing robot in a wind field by Xiaoyang WU, Zhiguo ZHANG, Wei HE, Jingyan QIN, Junhai ZHANG, Tingting MENG

“…In the simulation, the robot’s design is simplified, with some complex structures removed, to reduce computational costs and model complexity. …”
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Assessing hand motor function in chronic immune-mediated neuropathies: a proof-of-concept study using a data glove by Elisa Gilliam, Pascal Achenbach, Gernot J. Suemmermann, Manuel N. Wessely, Peter Rossmanith, Maike F. Dohrn, Jörg B. Schulz, Anne Waschbisch, Robert Brunkhorst

“…Wearables such as data gloves might be helpful, allowing repeated quantification of complex everyday life-relevant motor function of the hand. …”
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Fast Reflectance Spectral Profile Reconstruction Method for Full-waveform Hyperspectral LiDAR by Hui SHAO, Hulong ZHANG, Hui DAI, Yuwei CHEN, Long SUN, Heng XU, Xingyun LI

“…Moreover, it demonstrates excellent stability under various temperatures and lighting conditions. …”
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Evaluating the multitargeted potency of Pixuvri against cell cycle regulation proteins in cervical cancer by Mohammed Ali Alshehri, Hadil Alahdal, Akram Ahmed Aloqbi, Afnan Mohammed Shakoori, Ghadir Sindi, Rehab M. Bagadood, Nida Alsaffar, Mohammad Ahmad Alobaidy, Noof Abdulrahman Alrabiah, Md Khursheed, Abeer Al Tuwaijri, Abeer Al Tuwaijri

“…Interaction fingerprints highlighted key residues (4GLN, 4GLU, 3TRP), while pharmacokinetics, DFT computations, and WaterMap hydration site analysis supported its potential. Molecular dynamics (100 ns, NVT ensemble at 300K) validated stability by deviation and fluctuation studies and found many interactions to stabilize the complex, with binding free energy computations confirming its affinity. …”
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The Environmental Legal Framework of Mexican Caribbean Dunes: A Retrospective Case Study of Vegetation and Coastal Dune Loss in the Sian Ka’an Biosphere Reserve by Eloy Gayosso-Soto, Sergio Cohuo, Joan Alberto Sánchez-Sánchez, Laura Macario-González, Carmen Amelia Villegas-Sánchez, Alejandro Medina-Quej, Jorge Manuel Tello-Chan, Leopoldo Querubín Cutz-Pool, José Manuel Castro-Pérez

“…For coastal dunes, none of them consider topography, ecological function and a way to identify it in the field, making the surveillance highly complex and favoring land use changes, the removal of vegetation and dune geomorphology alteration. …”
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Genotype-dependent response to water deficit: increases in maize cell wall digestibility occurs through reducing both p-coumaric acid and lignification of the rind by Ana López-Malvar, Ana López-Malvar, Oscar Main, Oscar Main, Sophie Guillaume, Marie-Pierre Jacquemot, Florence Meunier, Pedro Revilla, Rogelio Santiago, Valerie Mechin, Valerie Mechin, Matthieu Reymond

“…This study emphasizes the complex, genotype-dependent responses to water deficit, underscoring the important roles of plasticity and stability in shaping the impact on maize cell wall digestibility; paving the way to breed for adapted genotypes to face climate changes.…”
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Aminoquinazolin-4(3H)-one derivatives as multitargeting therapeutics in Alzheimer's disease by Tajamul Hussain, Salman Alrokayan, Dilawar Hussain, Khurram Shoaib, Syeda Abida Ejaz, Steven Ford, Jamshed Iqbal

“…These findings were further supported by molecular dynamics (MD) simulations, indicating the substantial stability of the protein-ligand complex. Additionally, in-silico ADME modeling was utilized to analyze the pharmacokinetic profile. …”
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Chronic Exposure to Field-Level Thiamethoxam Impairs Gut Tissue and Reduces Honeybee (<i>Apis cerana</i>) Survival by Yulong Guo, Changsheng Ma, Wenzheng Zhao, Haiou Kuang, Yakai Tian, Haoyuan Zhang, Yunfei Xue, Hongmei Li-Byarlay, Kun Dong, Xueyang Gong

“…These findings demonstrate that TMX exposure induces complex, tissue-specific effects. This study provides a comprehensive understanding of the molecular and physiological impacts of TMX on <i>A. cerana</i>, offering valuable insights for the conservation and protection of this important pollinator species.…”
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Applying affect coding and dynamical systems mathematical modeling to understanding the role of emotional expression on the therapeutic relationship across an entire course of subs... by Gina Cipriano, Paul R. Peluso, Emma Bright, Blanka Hutarkova

“…These findings highlight the complex emotional dynamics in substance abuse treatment and underscore the importance of a stable therapeutic presence.Clinical significance/impact statementThe findings from this study highlight the importance of understanding emotional dynamics in the therapeutic relationship during substance abuse treatment. …”
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Inter-kingdom interactions and environmental influences on the oral microbiome in severe early childhood caries by Lingjia Weng, Yuqi Cui, Wenting Jian, Yuwen Zhang, Liangyue Pang, Yina Cao, Yan Zhou, Wei Liu, Huancai Lin, Ye Tao

“…Network analyses uncovered complex intra- and inter-kingdom interactions, underscoring cooperative and competitive dynamics. …”
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An animal model study of simplified optical navigation system-assisted percutaneous lumbar transforaminal puncture by B. N. Wenxiu Chai, Yuqing Chen, Li Sheng, Yong Huang

“…However, current research on optically-navigated puncture localization during PTED is still limited, with high equipment costs and complex operational techniques being the main barriers to widespread adoption. 3D Slicer is a powerful open-source medical image analysis and visualization platform that can be integrated with external optical trackers to construct a low-cost optical navigation system for assisted puncture procedures. …”
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Enhancing environmental decontamination and sustainable production through synergistic and complementary interactions of actinobacteria and fungi by Juliana M. Saez, Enzo E. Raimondo, Stefanie B. Costa-Gutierrez, Juan D. Aparicio, Domenica Mosca Angelucci, Enrica Donati, Marta A. Polti, Maria C. Tomei, Claudia S. Benimeli

“…Although challenges still exist, their potential to address complex problems has been demonstrated and deserves further investigation.…”
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Subtractive proteomics and reverse-vaccinology approaches for novel drug targets and designing a chimeric vaccine against Ruminococcus gnavus strain RJX1120 by Hou Dingding, Hou Dingding, Sher Muhammad, Irfan Manzoor, Sana Abdul Ghaffar, Hissah Abdulrahman Alodaini, Nadine MS. Moubayed, Ashraf Atef Hatamleh, Xu Songxiao

“…The results of molecular dynamics simulations further confirmed the stability of the vaccine-receptor complex under physiological conditions. …”
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The security outcome of the conflict between tradition and modernism in Afghanistan by Mokhtar Rahimi, Mohsen Eslami

“…In response, the hypothesis is put forward that with the arrival of manifestations of modern civilization in Afghanistan, especially since the era of Amanullah Khan, this society has gradually suffered an ideological split and has become fattened by fundamentalism as a result of the destructive conflict between modernist and traditionalist forces.Methods: This research is developmental in terms of its purpose and the research method is qualitative and of the type of document analysis and the tool for collecting information is whistleblowing.Results and Discussion: The data indicate that ideological conflicts between conservative and reformist forces in Afghanistan since the early 20th century have, while creating transformative waves, consistently had negative effects on the country's development and social stability process. …”
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