-
2601
A Novel YWHAG Variant L173S Causes Developmental and Epileptic Encephalopathy by Disrupting the Hydrophobic Internal Protein Structure
Published 2025-04-01“…Structural conservation analysis of YWHAG was conducted using Consurf and PyMol. …”
Get full text
Article -
2602
COMPOSITE MODIFICATOR OF ASPHALT-CONCRETE OBTAINED BY THE METHOD OF HIGH-TEMPERATURE SHEAR-INDUCED GRINDING OF CRUMB RUBBER AND SBS THERMOELASTOPLAST
Published 2018-10-01“…The use of crushed vulcanizate as a modifier is limited due to the complexity of obtaining a particle with a micro-size and complex surface organization. …”
Get full text
Article -
2603
Development of mercapto-phenyl-1,2,4-triazole bearing thio-quinoline as a novel class of tyrosinase inhibitors: an in vitro and in silico study
Published 2025-07-01“…Molecular dynamics simulations have further exhibited the high stability and compactness of the 12j–tyrosinase complex, with minimum RMSD fluctuations and stable hydrogen bonding patterns. …”
Get full text
Article -
2604
A Vegetable-Price Forecasting Method Based on Mixture of Experts
Published 2025-01-01“…The accurate forecasting of vegetable prices is crucial for policy formulation, market decisions, and agricultural market stability. Traditional time-series models often require manual parameter tuning and struggle to effectively handle the complex non-linear characteristics of vegetable price data, limiting their predictive accuracy. …”
Get full text
Article -
2605
Physical–Statistical Characterization of PM<sub>10</sub> and PM<sub>2.5</sub> Concentrations and Atmospheric Transport Events in the Azores During 2024
Published 2025-06-01“…Weak to moderate correlations were observed between PM concentrations and meteorological variables, indicating complex interactions influenced by atmospheric stability and long-range transport processes. …”
Get full text
Article -
2606
Monitoring of Overburden Failure with a Large Fractured-Height Working Face in a Deep Jurassic Coal Seam Based on the Electric Method
Published 2024-11-01“…Three roof boreholes were drilled in the auxiliary transportation roadway of adjacent working faces for dynamic monitoring by the resistivity method, which can better observe the whole process from failure to stability of the overburden. The results show that due to the complex sedimentary environment and large buried depth of coal seams in western China, there is a large deviation between the calculation results of the empirical formula of the fractured zone height under the “Regulations of buildings, water, railway and main well lane leaving coal pillar and press coal mining” (three regulations) and the simulation and on-site measurement. …”
Get full text
Article -
2607
THE ROLE OF AMBIDEXTERITY IN MEDIATING ENTREPRENEURIAL ORIENTATION AND BUSINESS PERFORMANCE IN SMES
Published 2025-04-01“…The data underwent rigorous analysis using Structural Equation Modelling (SEM), facilitated by SmartPLS software, to yield robust and comprehensive insights. …”
Get full text
Article -
2608
Distribution characteristics and value range of numerical simulation mechanical parameters in coal seam mining
Published 2025-07-01“…Medium sandstone has the widest distribution in bulk modulus and elastic modulus, while limestone exhibits high stability across multiple parameters. Moreover, through the analysis of simulation mechanical parameters of coal seams and primary lithologies in different regions, a reference system for the value ranges and outlier detection of numerical simulation mechanical parameters for coal-bearing strata was developed. …”
Get full text
Article -
2609
Multi-Target Firefighting Task Planning Strategy for Multiple UAVs Under Dynamic Forest Fire Environment
Published 2025-02-01“…Both algorithms were validated compared with traditional algorithms through simulation experiments, and the sensitivity analysis of different scenarios were conducted. Results from benchmark tests and case studies indicate that the improved MP–GWO algorithm outperforms the grey wolf optimizer (GWO), pelican optimizer (POA), Harris hawks optimizer (HHO), coyote optimizer (CPO), and particle swarm optimizer (PSO) in solving more complex optimization problems, providing better average results, greater stability, and effectively reducing flight time and path cost. …”
Get full text
Article -
2610
-
2611
Evolution of glacial lakes in Southern Patagonian Icefield between 1986 and 2023
Published 2025-07-01“…Of the lakes identified in 2023, moraine-dammed lakes accounted for the largest portion (165), followed by bedrock-dammed lakes (76) and ice-dammed lakes (72). A temporal analysis of the lakes by type revealed that (1) bedrock-dammed lakes exhibited the greatest stability, (2) moraine-dammed lakes showed the most significant growth in number and total area, with the number of lakes stagnating after 2016, and (3) ice-dammed lakes were the most dynamic and variable. …”
Get full text
Article -
2612
-
2613
Optimized step size control within the Rosenbrock solvers for stiff chemical ordinary differential equation systems in KPP version 2.2.3_rs4
Published 2025-07-01“…These solvers provide the desired stability and accuracy of results at an affordable yet large computational cost. …”
Get full text
Article -
2614
Development of High-performance Proton Transfer Reaction Time-of-Flight Mass Spectrometer
Published 2025-01-01“…This paper introduced a homemade high-performance proton transfer reaction time-of-fight mass spectrometer (PTR-TOF MS), which can be used for real-time online analysis and monitoring of complex organic gas mixtures. …”
Get full text
Article -
2615
Identification of natural compounds as potential inhibitors of Interleukin-23: virtual screening, ADMET, drug-likeness, and dynamic simulation
Published 2025-04-01“…Molecular dynamics (MD) simulation further confirmed the stability of the IL-23-L1 complex, highlighting a robust interaction between L1 and the target enzyme, with Tyr100 being one of the amino acids showing the highest frequency of interaction throughout the simulation. …”
Get full text
Article -
2616
Identification of Natural Sloshing Frequency in a Rectangular Tank Under Surge Excitation Using Coupled Eulerian–Lagrangian Method and Impulse Excitation Method
Published 2025-05-01“…However, existing theoretical models often rely on simplified assumptions that restrict their capacity to capture the complexities of fluid–structure interactions in baffled tanks. …”
Get full text
Article -
2617
Coordinated control strategy for HVDC frequency controllers in multi-area asynchronous grid
Published 2025-06-01“…Considering the results of the stability analysis, an optimization methodology for tuning the droop parameters of the frequency controller is proposed, employing an exhaustive search algorithm. …”
Get full text
Article -
2618
Gingerols and Shogaols of Zingiber officinale var. sunti Valeton as Potential Allosteric Agonists of Human GABAA Receptor by in silico Pharmacology Approach
Published 2025-06-01“…The MD simulation confirmed that the stability of the 10-shogaol/hGABAAR and 6-gingerol/hGABAAR complexes is equal to that of diazepam/hGABAAR. …”
Get full text
Article -
2619
DFT study of 1,4-diazabicyclo[2.2.2]octane (DABCO) based ionic liquids: Effect of alkyl chain and anion types
Published 2025-05-01“…By incorporating AIM and NBO analyses, we gained insight into the nature of bonding and charge distribution within the complexes. Larger anions like PF6¯, or BF4¯exhibit higher electronic stability than smaller halide anions. …”
Get full text
Article -
2620
Secure and Editable: A Blockchain Voting System Based on Chameleon Hash With Ephemeral Trapdoors
Published 2025-01-01“…We simulate and evaluate the system using Fabric 2.2, focusing on computational complexity and system stability. Analysis of experimental results shows that the blockchain-based voting system with an editable ballot mechanism proposed in this article has good computational cost and stability performance under normal use pressure.…”
Get full text
Article