Inverse catalysts: tuning the composition and structure of oxide clusters through the metal support by Luuk H. E. Kempen, Mie Andersen

“…This approach allows us to find trends such as the susceptibility to oxidation of the different systems and the range of stability of different cluster motifs. Our analysis highlights the importance of taking the diversity of sites exposed by metal–oxide interfaces into account in catalyst design studies.…”
Get full text

Veteran and first responder family members show distinct mental health networks centered on negative emotions by Johannes A. Karl, Warren N. Ponder, Jose Carbajal, Oleg N. Medvedev

“…The network demonstrated high stability across bootstrap analyses, with a correlation stability coefficient exceeding 0.59. …”
Get full text

The processed Sanguisorba officinalis L. triterpenoids prevent colon cancer through the TNF-α/NF-κB signaling pathway, combined with network pharmacology, molecular simulation dyna... by Chunli Gan, Yuanqiu Mu, Shah Syed Faizan Ali, Xuepeng Shi, Shuang Jiang, Zhengyang Wang, Xiaotian Wu, Xiaotong Wang, Zhibin Wang, Shulu Zhang, Zheng Feng, Chunjuan Yang

“…The main active compounds were identified using UPLC-Q-TOF-MS, and potential active compounds were screened through network pharmacology and molecular docking. The stability of the protein-ligand complexes was further assessed using molecular dynamics simulations.ResultsIn vivo experiments, treatment with ST significantly improved the clinical manifestations, Disease Activity Index (DAI) scores, and pathological lesions associated with colon cancer, with all drug administration groups outperforming the model group. …”
Get full text

Exploring shared therapeutic targets for Alzheimer’s disease and glioblastoma using network pharmacology and protein-protein interaction approach by Sushma Pradeep, Sushma Pradeep, M. R. Sai Chakith, S. R. Sindhushree, Pruthvish Reddy, Esther Sushmitha, Madhusudan N. Purohit, Divya Suresh, Nanjunda Swamy Shivananju, Ekaterina Silina, Natalia Manturova, Victor Stupin, Shiva Prasad Kollur, Chandan Shivamallu, Raghu Ram Achar

“…To further validate this interaction, molecular dynamics simulations (MDS) were performed using GROMACS, confirming the stability of the Luteolin-IL6 complex. Additionally, MM-PBSA binding energy calculations using AmberTools (−145.44 kJ/mol) provided further evidence of a strong and stable interaction. …”
Get full text

Ondas de densidad semántica para el análisis de la argumentación clínica multimodal en la formación de profesionales de la salud by Giovanni Garcia-Castro, Francisco Javier Ruiz-Ortega

“…The analysis of semantic waves demonstrated a progression in conceptual complexity and argumentative stability, highlighting the positive results of the training process on teachers' and students' ability to construct dense and coherent discourses. …”
Get full text

Advanced classification of optical water types and ensemble learning models for Chl-a inversion in Dongting and Poyang lakes using Sentinel-2 remote sensing: assessing the impact o... by Kai Xiong, Bin Deng, Jiang Liu, Zhixin Guan, Weizhi Lu, Changbo Jiang, Wei Luo, Han Rao, Longbin Yin, Kang Yang

“…Accurate and robust retrieval of chlorophyll-a (Chl-a) concentrations in optically complex lakes is critical for effective water quality monitoring, especially under frequent extreme climatic conditions. …”
Get full text

THE ROLE OF THE HUMANITIES AND SOCIAL SCIENCES IN HIGHER EDUCATION: INTERNATIONAL EXPERIENCE by N. Kliuchkovska

“…“Europe is still facing many long term and complex challenges. It takes profound knowledge and insight to really understand these challenges and how they affect us, and to guide us to solutions. …”
Get full text

Preparation and Properties of Sodium Alginate-Tannic Acid-Silver Bacteriostatic Hydrogel by Bingchao DUAN, Hongdan HAO, Yangyang ZHAO, Hezhen DU, Yiyao FU, Lan WANG, Song GAO, Guochao JIA, Feifei MENG, Shengqi MEI, Min WANG, Bowen YANG

“…The findings revealed that SA and TA could form a complex stabilized by hydrogen-bonding interactions, and both the carboxyl and hydroxyl groups in the complex participated in the reduction of silver ions. …”
Get full text

Structure-Based Identification of Natural MTH1 Inhibitors for Breast Cancer Therapy via Molecular Docking and Dynamics Simulations by Abdullah S. Alawam, Mubarak A. Alamri

“…PCA analysis revealed restricted conformational sampling, highlighting stabilization, particularly with ZINC14727630, ZINC14819291, ZINC14781695, and ZINC95099417. …”
Get full text

A Study of the Effect of Temperature on the Capacitance Characteristics of a Metal-<i>μ</i>hemisphere Resonant Gyroscope by Xiangxian Yao, Hui Zhao, Zhong Su, Xibing Gu, Sirui Chu

“…In order to capture this nonlinear behavior, the experimental data were smoothed and fitted using the LOESS method, revealing a complex trend of the capacitance variation with temperature. …”
Get full text

Identifying RAGE inhibitors as potential therapeutics for Alzheimer’s disease via integrated in-silico approaches by Inderjeet Bhogal, Vaishali Pankaj, Sudeep Roy

“…Furthermore, the trajectory analysis (DCCM and PCA) analyzed the dominant motions of residues and predicted the stability of protein-ligand complexes. …”
Get full text

Ionic Conductance, Thermal and Morphological Behavior of PEO-Graphene Oxide-Salts Composites by Mohammad Saleem Khan, Abdul Shakoor

“…The thermal stability studies reveal that incorporation of GO has somewhat enhanced the thermal stability of the films.…”
Get full text

New insights of cerium oxide nanoparticles in head and neck cancer treatment by Elif Tarakci, Sahra Esmkhani, Jamila Bayramova, Feride Melisa Bilgin, Kubra Kidik, Sevin Adiguzel, Yigithan Tufan, Ahsen Morva Yilmaz, Hulya Yilmaz, Ozgur Duygulu, Serpil Harbeck, Batur Ercan, Filiz Kaya, Digdem Aktoprakligil Aksu, Hulya Yazici, Hilal Yazici

“…Abstract Head and neck cancer (HNC) is a genetically complex cancer type having treatment difficulties due to affecting multiple organs in complex anatomical sites. …”
Get full text

The association of dietary nutrients consumption with hepatic steatosis and fibrosis from NHANES 2017–2020 by Qi Sheng, Qi Sheng, Qi Sheng, Shousheng Liu, Haiyang Yu, Huanchen Shi, Yongning Xin, Yongning Xin

“…Various variables, encompassing sociodemographic characteristics, and other potential confounders were considered to ensure the stability of the findings. Additionally, the analysis accounted for various covariates and employed restricted cubic spline analysis to examine potential nonlinear relationships. …”
Get full text

Identification of Online Health Information Using Large Pretrained Language Models: Mixed Methods Study by Dongmei Tan, Yi Huang, Ming Liu, Ziyu Li, Xiaoqian Wu, Cheng Huang

“…Significant discrepancies were observed in the models’ ability to distinguish scientifically verified knowledge from popular misconceptions and in their stability when processing complex linguistic and cultural contexts. …”
Get full text

Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches by Elahe Asadollahi, Alireza Zomorodipour, Zahra-Soheila Soheili, Babak Jahangiri, Majid Sadeghizadeh

“…The immunoglobulin kappa (Igκ) chain signal peptide was incorporated to improve secretion efficiency. The stability of the final MNEV construct in complex with TLR3, TLR4, and TLR9 was confirmed through binding analysis and refinement of the best-predicted 3D model. …”
Get full text

Evolutionary dynamics of the calcium/cation antiporter superfamily in Brassicaceae: codon usage, selection pressure, and BnCaCAs role in abiotic stress response by Amin Abedi, Mohadece Pourkarimi Daryakenari, Fatemeh Zare, Somayeh Allahi, Zahra Hajiahmadi

“…Codon usage bias (CUB) analysis showed CaCA genes have low codon bias and CUB indices indicated a complex interplay between mutational and selective pressures, highlighting the influence of natural selection and mutational biases in shaping these genes. …”
Get full text

Novel coronavirus SARS-CoV-2 in the context of global epidemiology of coronavirus infections by M. V. Supotnitskiy

“…However, due to the higher stability of the virus when penetrating the endosomes of the cell and the effectiveness of the replication/transcription complex, the virus replicates to large enough numbers to transmit easily from ill people to healthy. …”
Get full text

Comprehensive Management Approaches for Acute Distal Radioulnar Joint Instability Post distal End Radius Fracture by Anteshwar Birajdar, Sushant Kumar, Mukesh Phalak, Tushar Chaudhari, Damarla Meghana

“…Conclusion: The major findings of analysis have suggested that the time, effort, and cost of TFCC repair do not appear to be necessary, however, there may be trade-offs between various treatments, with K-wire stabilization offering a better range of motion and cast immobilization a stronger grip.…”
Get full text

Optimizing mRNA Vaccine Degradation Prediction via Penalized Dropout Approaches by Hwai Ing Soon, Azian Azamimi Abdullah, Hiromitsu Nishizaki, Latifah Munirah Kamarudin

“…Predicting mRNA vaccine degradation rates with precision is essential for ensuring stability, efficacy, and optimal deployment strategies, particularly given the unique challenges posed by their rapid degradation. …”
Get full text