Characterizing US Spatial Connectivity and Implications for Geographical Disease Dynamics and Metapopulation Modeling: Longitudinal Observational Study by Giulia Pullano, Lucila Gisele Alvarez-Zuzek, Vittoria Colizza, Shweta Bansal

“…Such geographically dispersed outbreaks place a significant strain on national public health resources and necessitate complex metapopulation modeling approaches for predicting disease dynamics and control design. …”
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Cross-feeding-based rational design of a probiotic combination of Bacterides xylanisolvens and Clostridium butyricum therapy for metabolic diseases by Shanshan Qiao, Tao Wang, Jingzu Sun, Junjie Han, Huanqin Dai, Mengxuan Du, Lan Yang, Chun-Jun Guo, Chang Liu, Shuang-Jiang Liu, Hongwei Liu

“…This work demonstrates the development of new LBP therapy for metabolic diseases from cross-feeding microbial pairs which exerted better self-stability and robust efficacy in complex intestinal environments compared to conventional single-strain LBPs.…”
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Control Basado en Eventos de Sistemas de Primer Orden Con Retardo by Ángel Ruiz, Jorge E. Jiménez, José Sánchez, Sebastián Dormido

“…By means of the proposed scheme, a stability analysis is addressed and a simple tuning methodology with effective interpretation is proposed. …”
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Biopolymer encapsulation for improved probiotic delivery: Advancements and challenges by Srirengaraj Vijayaram, Reshma Sinha, Caterina Faggio, Einar Ringø, Chi-Chung Chou

“…Focusing on the interactions between biopolymers and probiotics reveals how customized encapsulation approaches can enhance probiotic stability, survival, and functionality. Through detailed comparative analysis of the effectiveness of various encapsulation methods, we identify key strategies for optimizing probiotic deployment in challenging conditions such as high-temperature processing, acidic environments, and gastrointestinal transit. …”
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Development of Ofloxacin-Loaded CS/PVA Hydrogel for the Treatment of Metritis in Bovine by Priyanka Kumari, Manish Kumar Shukla, Ashutosh Tripathi, Janmejay Pandey, Amit K. Goyal

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Oxidation-induced destabilization of polymorphic α-synuclein fibrils: insights from molecular dynamics by Tohir Akramov, Tohir Akramov, Parthiban Marimuthu, Parthiban Marimuthu, Mukhriddin Makhkamov, Mukhriddin Makhkamov, Aamir Shahzad, Rasulbek Mashalov, Jamoliddin Razzokov, Jamoliddin Razzokov, Jamoliddin Razzokov

“…While oxidative stress has been implicated in αSyn aggregation, its precise effects on fibril stability remain unclear. In this study, we use molecular dynamics (MD) simulations and enhanced sampling techniques to investigate the impact of oxidation-induced modifications on the conformational stability of αSyn polymorph fibrils. …”
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Integrative snRNA‐seq, molecular docking and dynamics simulations identifies Lasmiditan as drug candidate for Alzheimer's disease by Martin Nwadiugwu, Md Selim Reza, Boluwatife Afolabi, Demetrius M. Maraganore, Hui Shen, Hongwen Deng

“…Molecular docking and dynamic simulations analysis evaluated interactions between DERs and 2200 Food and Drug Administration‐approved drugs to assess binding stability, whilst pharmacokinetic parameters relevant to blood–brain barrier permeability were evaluated. …”
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Genome-wide analyses reveal intricate genetic mechanisms underlying egg production efficiency in chickens by Lizhi Tan, Xinyu Cai, Yuan Kong, Zexuan Liu, Zilong Wen, Lina Bu, Yuzhan Wang, Xiaojun Liu, Zhiwu Zhang, Jianlin Han, Dandan Wang, Yiqiang Zhao

“…Consistently, functional analysis of associated genes demonstrates that egg production efficiency benefits from multiple physiological functions. …”
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Combined association of systemic inflammatory response index and prognostic nutritional index with survival among US cancer survivors by Bingqing Luo, Xiaoyan Tan, Lin Chen, Kang Zhou, Shifeng Lou

“…Subgroup and interaction analysis confirmed the stability of the core results. …”
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Exploring spatio-temporal heterogeneity and inter-domain ecological networks of biological community in a marine ranching habitat: Implications for fishery resources conservation by Lei Zeng, Guobao Chen, Tingting Zheng, Yuxiang Chen, Jie Yu, Wuhui Li

“…The IDEN analysis revealed that 23 species such as Chaetoceros densus, Centropages tenuiremis, and Parargyrops edita played a key role in maintaining the stability of the biological communities in the studied sea area. …”
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Exploring the potential role of GyrA inhibiting quinoline analog: an in silico study by Soumyadip Ghosh, Sudha Ramaiah

“…MD simulations validated the dynamic stability of M2 and gyrA complexes (wild-type and mutant), whereas MM/PBSA analysis confirmed strong binding energetics. …”
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Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry by Benediktus Yohan Arman, Rebecca Clarke, Tehmina Bharucha, Laura Gomez Fernandez, John Walsby-Tickle, Michael Deats, Sara Mosca, Qianqi Lin, Sneha Banerjee, Shrikrishna R. Chunekar, Kundan D. Patil, Sunil Gairola, Susanna Dunachie, Hamid A. Merchant, Robert Stokes, Rutendo Kuwana, Alexandrine Maes, Jean-Philippe Charrier, Fay Probert, Céline Caillet, Pavel Matousek, James McCullagh, Paul N. Newton, Nicole Zitzmann, Bevin Gangadharan

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Reliable numerical scheme for coupled nonlinear Schrödinger equation under the influence of the multiplicative time noise by Muhammad Zafarullah Baber, Nauman Ahmed, Muhammad Waqas Yasin, Muhammad Sajid Iqbal, Ali Akgül, Murad Khan Hassani, Muhammad Jawaz

“…For the computational results, the proposed stochastic backward Euler scheme is developed and its consistency is derived in the mean square sense. For the linear stability analysis, Von-Neumann criteria is used, given proposed stochastic scheme is unconditionally stable. …”
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Investigation of Mutual Behavior of Stochastic Normally Distributed Processes with Additive Amplitude Randomization by S. A. Pyko, N. S. Pyko, O. A. Markelov, Yu. D. Uljanitski, M. I. Bogachev

“…The joint analysis of several signals is essential for better understanding of the principles underlying the complex systems dynamics. …”
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MYCOSIS FUNGOIDES PROGRESSING TO PERIPHERAL T-CELL LYMPHOMA AND THE POTENTIAL ROLE OF ROMIDEPSIN THERAPY by Bengisu Ece Duman, Ceren Deveci, Birol Güvenç

“…Immunohistochemical analysis showed positivity for CD3+, CD4+, CD7+, GATA3+, and Ki-67 expression. …”
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Kanamycin and G-Quadruplexes: An Exploration of Binding Interactions by Gianmarco Gualtieri, Emanuele Liborio Citriniti, Roberta Rocca, Valentina Arciuolo, Jussara Amato, Antonio Randazzo, Stefano Alcaro

“…To identify potential drug candidates capable of interacting with these complex DNA formations, docking studies and molecular dynamics (MDs) simulations were conducted. …”
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Psychometric properties and longitudinal measurement invariance of the treatment-induced neuropathy assessment scale in the Chinese cancer chemotherapy population by Yanfei Jin, Yang Li, Lina Xiong, Chulei Tang, Hongwen Ma

“…Abstract Treatment-induced peripheral neuropathy is one of the most complex toxicities to diagnose and manage in cancer patients. …”
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Discovery of novel DdlA inhibitors in multidrug-resistant Pseudomonas aeruginosa using virtual screening, molecular docking, and dynamics simulations by Fahad M. Aldakheel, Shatha A. Alduraywish

“…Detailed interaction analyses revealed significant salt bridges and hydrogen bonds with active site residues, which enhance the stability of the complex. Density Functional Theory (DFT) analysis and MMPBSA calculations also provided insights into electronic properties and binding free energy, respectively. …”
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INDUSTRIAL APPROBATION OF COMBINED COUNTERSINK-TAP TOOL by Nurulla M. Vagabov, Ali Z. Kurbanov, Marina A. Magomedovа

“…Objectives Based on a critical analysis of the results of complex studies, we set out to demonstrate the advantages, as compared with existing technologies, of a developed technology that uses a new cutting scheme with a combined countersink-tap tool. …”
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A systematic literature review on socio-ecological value scorecards for advancing sustainable smart agriculture by Saeed Niksaz, Fisnik Dalipi, Anita Mirijamdotter

“…Abstract Agriculture, vital for sustenance and economic stability, faces growing pressures from resource scarcity, urbanization, and a surging global population. …”
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