Identification of novel antioxidant and anti-inflammatory peptides from bovine hemoglobin by computer simulation of enzymolysis, molecular docking and molecular dynamics by Xuan-Ying Xin, Chao-Hui Ruan, Yi-Hui Liu, Huai-Na Jin, Sung-Kwon Park, Sun-Jin Hur, Xiang-Zi Li, Seong-Ho Choi

“…Due to the structural diversity and complex mechanisms of action of bioactive peptides, screening for specific functional peptides is often challenging. …”
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Evaluating N₂O emissions and carbon sequestration in temperate croplands with cover crops: insights from field trials by V. Nasser, R. Dechow, M. Helfrich, A. Meijide, P. S. Rummel, P. S. Rummel, H.-J. Koch, R. Ruser, L. Essich, K. Dittert

“…Yet, their influence on nitrous oxide (<span class="inline-formula">N₂O</span>) emissions – a potent greenhouse gas – presents a complex challenge, with findings varying across different studies. …”
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Linking Electrocardiogram and Echocardiogram: Comparing Classical Machine Learning and Deep Learning Neural Networks for the Detection of Regional Wall Motion Abnormalities by Shantanu M. Joshi, Hana R. Shaik, Shivam Rai Sharma, Philip Strong, Uma Srivatsa, Imo Ebong, Hyoyoung Jeong, Chen-Nee Chuah, Lihong Mo

“…Future studies are needed to determine the optimal CNN architecture that balances the target classifier performance and computational efficiency for ease of deployment with larger datasets.…”
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Identification and Characterization of Antiviral Activity of Synthetic Compounds Against Mayaro Virus by Ana Paula Andreolla, Andrea Cristine Koishi, Alessandra Abel Borges, Larissa Albuquerque de Oliveira, Viviane Guedes de Oliveira, Nerilson Marques Lima, Eloah Pereira Ávila, Pedro Pôssa de Castro, Giovanni Wilson Amarante, Mauro Vieira de Almeida, Juliano Bordignon, Claudia Nunes Duarte dos Santos

“…<b>Background/objectives:</b> In Brazil, the co-circulation of arboviruses—such as dengue, Zika, yellow fever, and Chikungunya viruses—creates a complex epidemiological landscape, drawing attention from health authorities due to high morbidity and mortality rates. …”
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Trojan-horse silk fibroin nanocarriers loaded with a re-call antigen to redirect immunity against cancer by Luca Mastracci, Patrizio Castagnola, Elia Bari, Francesca Ferrera, Tiziana Altosole, Sara Perteghella, Pierluigi Mauri, Rossana Rossi, Giulia Passignani, Martina Galati, Giuseppina Iliana Astone, Maddalena Mastrogiacomo, Daniela Fenoglio, Dario Di Silvestre, Maria Luisa Torre, Gilberto Filaci

“…Cancer dimensions/survival time were monitored, while, at the molecular level, system biology approaches based on graph theory and experimental proteomic data were performed.Results SFNs were efficiently in vitro uptaken by cancer and dendritic cells. …”
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An immunoinformatics approach in designing high-coverage mRNA multi-epitope vaccine against multivariant SARS-CoV-2 by Ernawati Arifin Giri-Rachman, Al Mirahma Febri Kurnianti, Rizarullah, Aditya Hanung Setyadi, Anita Artarini, Marselina Irasonia Tan, Catur Riani, Dessy Natalia, Reza Aditama, Husna Nugrahapraja

“…Furthermore, molecular docking analysis revealed potent interactions between the validated 3D structure and the TLR4 and BCR receptors, while molecular dynamic simulations confirmed the stability of the VC-TLR4 and VC-BCR complexes. Additionally, mRNA codon optimization was performed to enhance vaccine expression efficiency, and secondary structure analysis indicated that the designed mRNA vaccine possessed a stable conformation. …”
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Presenting the Model of Effective Factors on Smart Governance in the Country by Ghaem Gheiravani, Mohammad Montazeri, Shams Sadat Zahedi

“…One of the most important opportunities that information technology presents to statesmen and managers is increasing accessibility, strengthening efficiency and re-engineering the architecture of the government and the possibility of making it more responsive. …”
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Predicting the strengths of basalt fiber reinforced concrete mixed with fly ash using AML and Hoffman and Gardener techniques by Kennedy C. Onyelowe, Viroon Kamchoom, Shadi Hanandeh, Ahmed M. Ebid, José Luis Llamuca Llamuca, Juan Carlos Cayán Martínez, Evlin Rose, Paul Awoyera, Siva Avudaiappan

“…These models benefit from advanced ensemble techniques that efficiently handle non-linear patterns and noise. SVR also performs admirably, whereas GEP and GMDHNN exhibit weaker predictive capabilities due to limitations in handling complex data dynamics. …”
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Characterization of a blaKPC-3-carrying plasmid in a clinical isolate of Klebsiella pneumoniae belonging to the emerging successful clone ST147 by Esther Recacha, Mercedes Delgado-Valverde, Marina R. Pulido, Elena Pérez-Nadales, Patricia Pérez-Palacios, Inés Portillo-Calderón, Juan Manuel Sánchez-Calvo, Irene Gracia-Ahufinger, Álvaro Pascual

“…ABSTRACT Klebsiella pneumoniae ST147 has emerged as a successful clone able to efficiently disseminate a number of carbapenemases, including blaKPC. …”
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Calculation Model of Multi-roll Straightening Process Based on Bilinear Hardening and Power Hardening by ZHU Xiaoyu, CHENG Zixing, WANG Xiaogang, HAN Peisheng

“…For example, the power model—more consistent with the tensile stress-strain curve—shows a 4.65% error between theory, experiment, and simulation for total straightening force. Selecting an appropriate material model based on specific material characteristics is crucial to ensure accuracy and efficiency in the straightening process. …”
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Development and Comparison of Interrupt-Based and Analog-to-Digital Converter Algorithms for Seed Counting in Precision Planters by A. Ghaffarnezhad, H. Navid, H. Karimi

“…Both developed circuits featured the deployment of the STM32F103C8T6 microcontroller, renowned for its robust capabilities and cost efficiency.In the interrupt-based algorithm's development, the microcontroller's external interrupt was used, selecting its sensitivity to detect both rising and falling edges. …”
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Managing Social Condominiums by Luz María Vergara d´Alençon

“…The strategies altogether seek to achieve autonomous condominiums in which homeowners have the tools and the capacities to maintain an internal organisation, and have access to the professional services that allow them to provide adequate maintenance in the long-term, and manage the existing but limited resources efficiently. The dissertation contributes to filling knowledge gaps regarding the concept of housing management in the Latin American context. …”
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Research on Model Reconstruction Methods for Partial Point Cloud Information Loss by Zhengping CHANG, Guoshuai YUAN, Jiuhua LI, Yang ZHAO, Zhongqi WANG

“…However, large-sized and structurally complex parts face challenges such as blocks, which result in incomplete point cloud information. …”
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Development of a comprehensive model to predict stock prices in the stock market with an interpretive structural modeling approach by Shiva Rezaeyan, Mohammad Taleghani, Azita Sherej Sharifi

“…After consolidating the responses, 15 criteria were selected as significant for predicting stock prices in the stock exchange. …”
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Sustainable development of Cuban agricultural economy: Policy and practice by Lihua Hu, Chengjiu Wang, Ping He

“…Researchers must flexibly select methods based on specific research questions and objectives to enhance scientific-practical relevance. …”
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The Effect of Hydraulic Partitioning on Prediction the Rate of Bed Load Transport in Gravel-bed Rivers using Support Vector Machine by Kiyoumars Roushangar, Mohammad Hosseini, Saman Shahnazi

“…Prediction ability of bed load transport is variable due to complexities that governs fluvial sediment transport in different flow conditions. …”
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Analysis and Prioritization of Indicators of Urban Development Strategy In the neighborhoods of the eight district of Shiraz by Issa Ebrahimzadeh, Mostafa Istgaldi, Fazel Hajizadeh

“…The statistical population of this study is citizens of four neighborhoods of the neighborhoods of the eight district of Shiraz (N = 24871), which was selected using Cochran formula. 318 people were selected and a proportional to each neighborhood population was distributed randomly in the neighborhood. …”
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The Circular Kitchen by Bas Jansen

“…However, existing methods do not fully incorporate the complex, multiple use cycles inherent in circular products and components. …”
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COOLFACADE by Alejandro Prieto Hoces

“…Increasing cooling needs in the built environment present an important and complex challenge for the design of sustainable buildings and cities. …”
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Presenting the Model of Aligning the Individual Development Program (IDP) with the Career Path, Based on the Foundation's data-theorizing Approach by Ali Kafami Ladani, Abdolali Keshtegar, Aleme Keikha

“…Also, since the success of the organization depends on the realization of the goals and needs of the individual and the organization in a balanced manner, and the methods proposed (individual development program and career path planning) each emphasize only one dimension (individual and organization), and it seems that the application of each alone will not lead to the realization of the desired results of the organization, And on the other hand, considering the studies conducted in the field and the lack of a comprehensive model that examines the individual's development plan in line with the needs of the organization, the results of this research will help organizations create a better fit between the job and the employee, ultimately leading to the efficiency and effectiveness of organizational activities.Case study The statistical population of this study consisted of 16 academic experts, scholars, and consultants in the field of human resources.Materials and Methods The sampling method for this research was non-probability and purposive, and data were collected using a semi-structured interview approach.Discussion and Results After conducting the initial semi-structured interviews, a set of initial themes was collected during the open coding process and categories were extracted from them; then, in the axial coding stage, the link between these categories was determined under the headings of causal conditions, axial phenomenon, strategies, contextual factors, intervening conditions, and consequences of aligning the individual development program with the career path in the form of the axial coding paradigm; and then, in the selective coding stage, the storyline was drawn and the initial model was calculated.ConclusionThe results showed that the causal factors for aligning the individual development program with the career path are: the necessity of job-employee fit, lack of structure in the learning and development process, speed of change, reduction in key organizational capabilities, and reduction in employee organizational belonging. …”
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