Structure-based molecular screening and dynamic simulation of phytocompounds targeting VEGFR-2: a novel therapeutic approach for papillary thyroid carcinoma by Shuai Wang, Lingqian Zhang, Wenjun Zhang, Xiong Zeng, Jie Mei, Weidong Xiao, Lijie Yang

“…Additionally, the selected compounds exhibited highly favorable ADMET properties, including optimal water solubility, efficient gastrointestinal absorption, and a non-hepatotoxic profile, all aligning with Lipinski’s rule of five. …”
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Integration of theoretical principals of psychosomatic medicine and practice of Balint supervision in physicians in the promotion of effective professional communication by V A Vinokur, T A Karavaeva

“…The history of the relations and common principles related to the attention to the complexed issues of physician-patient communication and the therapy in psychosomatic disorders which becomes more successful due to the impact of analytical Balint supervision, are analyzed. …”
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Numerical Investigation on Influential Factors for Quality of Smooth Blasting in Rock Tunnels by Baoping Zou, Zhipeng Xu, Jianxiu Wang, Zhanyou Luo, Lisheng Hu

“…A general control strategy for smooth blasting is too difficult to be available due to the uncertainties and complexity of rock masses, as well as the varying blasting operations. …”
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Optimizing Clinical Decision Support System Functionality by Leveraging Specific Human-Computer Interaction Elements: Insights From a Systematic Review by Ali Azadi, Francisco José García-Peñalvo

“…Likewise, “alerts” provide timely information for effective decision-making and, simultaneously, are designed to avoid overwhelming users and maintain system efficiency. “Simplification” and “mental effort” also optimize workflows and reduce complexity. …”
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Current Status and Analysis of Key Technologies in Automatic Transplanters for Vegetables in China by Bo Cheng, Huarui Wu, Huaji Zhu, Jie Liang, Yisheng Miao, Youlin Cui, Weitang Song

“…However, automatic transplanters are structurally complex, with diverse components, each design and function offering its own advantages and limitations. …”
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A novel canopy water indicator for UAV imaging to monitor winter wheat water status by Meiyan Shu, Zhenghang Ge, Yang Li, Jibo Yue, Wei Guo, Yuanyuan Fu, Ping Dong, Hongbo Qiao, Xiaohe Gu

“…The utilization of UAV-based imaging systems for precise assessment of crop hydration levels plays a pivotal role in optimizing irrigation strategies and enhancing the efficiency of agricultural water resource management. …”
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The use of non-traditional plant raw materials for the recipe composition of chips by O. V. Perfilova, K. V. Bryksina, Z. Y. Rodina

“…The production of multicomponent chips is currently relevant, since the combination in the formulation of various plant ingredients rich in physiologically active substances can ensure that the finished product contains a complex of functional components. The article investigates the possibility of using plant materials such as apple pomace puree, pumpkin puree, corn flour and calendula powder when creating a recipe composition for new types of chips for healthy diet. …”
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Investigating employment patterns and determinants in the European Union through panel data insights by Vasilescu Maria Denisa, Stănilă Larisa, Crivoi Silvana, Belu Maria Berta

“…The selected indicators covered the economic, educational, and social dimensions, providing a complex vision of employment and how it can be improved. …”
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Aero-Engine Blade Defect Detection: A Systematic Review of Deep Learning Models by Yusra Abdulrahman, M. A. Mohammed Eltoum, Abdulla Ayyad, Brain Moyo, Yahya Zweiri

“…The visual inspection of aero-engine blades is a complex process that requires extensive knowledge and experience. …”
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Does Socioeconomic and Environmental Factors Exacerbate Undernourishment in Asia and Africa? by Neng Zulfa Azhar, Dito Alif Pratama, Amanca Pamalina Lapasa

“… This study investigates the impact of socioeconomic and environmental factors on undernourishment, across seven selected countries in Asia and Africa from 2001 to 2020. …”
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An automated construction method of 3D knowledge graph based on multi-agent systems in virtual geographic scene by Yukun Guo, Jun Zhu, Jianlin Wu, Jinbin Zhang, Zhihao Guo, Weilian Li, Heng Zhang

“…However, the multitude of object types and complex relationships they contain make it challenging to display embedded geographic knowledge. …”
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The Effect of Occupancy and Environmental Physical Variables on Classrooms’ Natural Ventilation: A Path Modeling Approach by Rogério Duarte, António Moret Rodrigues, Fernando Pimentel, Maria da Glória Gomes

“…In spite of the statistical significance of the path model as a whole and its detailed causal relationships (direct, indirect, and feedback), only 58% of classroom ventilation variance is explained by the selected input variables. Because naturally ventilated classrooms depend significantly on occupants’ interactions with the built environment, i.e., opening/closing windows and blinds, extending path modeling to include additional personal and context-related drivers of occupants’ behavior would allow for further insights into the complex multi-domain topic of natural classroom ventilation.…”
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Highly parallel optimisation of chemical reactions through automation and machine intelligence by Joshua W. Sin, Siu Lun Chau, Ryan P. Burwood, Kurt Püntener, Raphael Bigler, Philippe Schwaller

“…Our approach effectively navigates the complex reaction landscape with unexpected chemical reactivity, outperforming traditional experimentalist-driven methods. …”
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Aerobic oxidative bromination and iodination enabled by alloxan and ascorbic acid to mimic flavin-dependent halogenases by Shiqi Zhang, Guang-xun Li, Dongmei Fang, Xia Zhang, Shangjing Chen, Xin Cui, Zhuo Tang

“…This approach yields various important monobromide and iodide products with high efficiency, excellent selectivity, and good functional group tolerance. …”
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Multi-objective programming method for ship weather routing based on fusion of A* and NSGA-II by Yuankui LI, Jiyuan SUO, Dongye YU, Xinyu ZHANG, Fang YANG, Xuefeng YANG

“…All routes can successfully avoid areas with severe weather conditions, and the most suitable route for the ship can be selected according to the decision-makers' needs. ConclusionIn summary, the proposed method can be applied to optimize ship ocean routes under multiple constraint conditions and identify routes that meet the voyage objectives, thereby reducing operational costs, improving shipping efficiency and providing support for ship meteorological navigation and future intelligent ship navigation.…”
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Copper-catalyzed enantioselective three-component radical 1,4-perfluoroalkylamination of 1,3-dienes by Xiaoyan Shangguan, Lihan Zhu, Yingzi Zhang, Yan Li, Qian Zhang

“…Abstract Catalytic enantioselective three-component aminative difunctionalization of readily available 1,3-dienes offers a straightforward methodology to fast access significant and complex chiral allylic amines. Nevertheless, compared to the widely studied two-component reactions, the three-component reactions, especially using anilines—very common bulk feedstock chemicals as aminating reagents are underdeveloped. …”
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Multi-Viewpoint Assessment of Urban Waterfront Skylines: Fractal and Spatial Hierarchy Analysis in Shanghai by Jian Zhang, Yi Wang, Xi Luo, Wen-Lei Luan

“…The framework consists of: (1) selecting eight representative viewpoints along the Huangpu River using visual cognition theory and GIS tools; (2) calculating skyline contour complexity using fractal dimension models; (3) establishing spatial hierarchy coefficients to measure depth gradients of building clusters; and (4) validating the results through visual field analysis and local skyline planning guidelines. …”
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Generalized MPC-DSVPWM Methods: Reduction Techniques and Explainable Machine Learning With Conformal Prediction for PMSM Drives by Hasan Ali Gamal Al-Kaf, Sadeq Ali Qasem Mohammed, Kyo-Beum Lee

“…Additionally, machine learning methods have been implemented; however, they require complex optimization methods, as the classification number increases exponentially with the level of the inverter. …”
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A Dual-channel Progressive Graph Convolutional Network via subgraph sampling by Wenrui Guan, Xun Wang

“…Graph Convolutional Networks (GCNs) demonstrate an excellent performance in node classification tasks by updating node representation via aggregating information from the neighbor nodes. Note that the complex interactions among all the nodes can produce challenges for GCNs. …”
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Diversity of Drosophila egg patterning: The missing tools to explore embryonic axis formation by Helen L. Stott, Nir Yakoby, Nir Yakoby

“…We address current challenges in achieving these goals, such as genetic markers, selectable markers, and the efficiency of CRISPR/Cas9 mediated genomic editing.…”
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