Optimization of the Pedagogical Process in Teaching Chemistry to First-Year Students of the Ural State Medical University by E. Yu. Ermishina, N. A. Naronova, N. N. Kataeva, K. O. Golitsyna, N. A. Belokonova

“…The pedagogical process carried out in teaching chemistry to first-year students of the medical and preventive faculty is a complex system that includes target, content, activity, performance, resource components. …”
Get full text

Reverse vaccinology and immunoinformatics approaches for multi-epitope vaccine design against Klebsiella pneumoniae reveal a novel vaccine target protein by Mayada M. Elfadil, Samah Omer A. Samhoon, Moaaz M. Saadaldin, Sabah A.E. Ibrahim, Ahmed Abdelghyoum M. Mohamed, Omnia H. Suliman, Osama Mohamed, Nadzirah Damiri, Mohd Firdaus-Raih, Sofia B. Mohamed, Qurashi. M. Ali

“…The construct was further optimized for mammalian expression, achieving an ideal GC content (48.27 %) and a codon adaptation index (CAI) of 1.0, facilitating efficient in silico cloning into the pcDNA3 vector. …”
Get full text

Constitutive model of metal rubber material considering plastic accumulation behavior by FENG Zhipeng, YANG Fang, FU Hailong, AI Shigang, WANG Yue, YUAN Liangyang

“…This advanced model provides an accurate description of the complex interaction mechanisms occurring among internal coils during loading and unloading processes.…”
Get full text

Characterization of a blaKPC-3-carrying plasmid in a clinical isolate of Klebsiella pneumoniae belonging to the emerging successful clone ST147 by Esther Recacha, Mercedes Delgado-Valverde, Marina R. Pulido, Elena Pérez-Nadales, Patricia Pérez-Palacios, Inés Portillo-Calderón, Juan Manuel Sánchez-Calvo, Irene Gracia-Ahufinger, Álvaro Pascual

“…ABSTRACT Klebsiella pneumoniae ST147 has emerged as a successful clone able to efficiently disseminate a number of carbapenemases, including blaKPC. …”
Get full text

Challenges and Obstacles in the Development of Winter Sports Tourism in the Ski Slopes of Tehran by Siavash Imeni, Leyla Asadpour Shirazi

“…The results showed a reliability coefficient above 0.7, indicating that the tool was reliable. …”
Get full text

An azo substituted quinoline‐malononitrile enzyme‐activable aggregation‐induced emission nanoprobe for hypoxia imaging by Zhirong Zhu, Shichang Liu, Xupeng Wu, Qianqian Yu, Yi Duan, Shanshan Hu, Wei‐Hong Zhu, Qi Wang

“…Abstract The development of efficient aggregation‐induced emission (AIE) active probes is crucial for disease diagnosis, particularly for tumors and cardiovascular diseases. …”
Get full text

Blockade of αvβ6 and αvβ8 integrins with a chromogranin A-derived peptide inhibits TGFβ activation in tumors and suppresses tumor growth by Anna Maria Gasparri, Arianna Pocaterra, Barbara Colombo, Giulia Taiè, Chiara Gnasso, Alessandro Gori, Federica Pozzi, Andrew Smith, Fulvio Magni, Alessia Ugolini, Matteo Doglio, Maria Chiara Bonini, Anna Mondino, Angelo Corti, Flavio Curnis

“…Abstract Background The αvβ6- and αvβ8-integrins, two cell-adhesion receptors upregulated in many solid tumors, can promote the activation of transforming growth factor-β (TGFβ), a potent immunosuppressive cytokine, by interacting with the RGD sequence of the latency-associated peptide (LAP)/TGFβ complex. We have previously described a chromogranin A-derived peptide, called “peptide 5a”, which recognizes the RGD-binding site of both αvβ6 and αvβ8 with high affinity and selectivity, and efficiently accumulates in αvβ6- or αvβ8-positive tumors. …”
Get full text

Managing Social Condominiums by Luz María Vergara d´Alençon

“…They are developed from the capacity of the third sector organisation as intermediary, meaning that they respond to catalyst and implementer roles to address management challenges at the condominium level by contributing to increase the community’s capacities and level the built environment conditions. Given the social complexities of deprived neighbourhoods, integral interventions, but also trained organisations, are required. …”
Get full text

Development and Comparison of Interrupt-Based and Analog-to-Digital Converter Algorithms for Seed Counting in Precision Planters by A. Ghaffarnezhad, H. Navid, H. Karimi

“…Both developed circuits featured the deployment of the STM32F103C8T6 microcontroller, renowned for its robust capabilities and cost efficiency.In the interrupt-based algorithm's development, the microcontroller's external interrupt was used, selecting its sensitivity to detect both rising and falling edges. …”
Get full text

Lightweight Apple Leaf Disease Detection Algorithm Based on Improved YOLOv8 by LUO Youlu, PAN Yonghao, XIA Shunxing, TAO Youzhi

“…To reduce the incidence of apple diseases and increase fruit yield, developing efficient and fast apple leaf disease detection technology is of great significance. …”
Get full text

Research on Model Reconstruction Methods for Partial Point Cloud Information Loss by Zhengping CHANG, Guoshuai YUAN, Jiuhua LI, Yang ZHAO, Zhongqi WANG

“…However, large-sized and structurally complex parts face challenges such as blocks, which result in incomplete point cloud information. …”
Get full text

Development of a comprehensive model to predict stock prices in the stock market with an interpretive structural modeling approach by Shiva Rezaeyan, Mohammad Taleghani, Azita Sherej Sharifi

“…After consolidating the responses, 15 criteria were selected as significant for predicting stock prices in the stock exchange. …”
Get full text

Sustainable development of Cuban agricultural economy: Policy and practice by Lihua Hu, Chengjiu Wang, Ping He

“…Researchers must flexibly select methods based on specific research questions and objectives to enhance scientific-practical relevance. …”
Get full text

Deep Learning Based 3D Visualization Health Condition Monitoring Method for Anchor Digging Machines by YANG Xueqi, GAO Xinqin, ZHENG Haiyang, YANG Jun

“…ObjectiveIn coal mining, anchor digging machines operate under harsh and complex conditions. They are subjected to high-intensity loads, resulting in frequent failures, and the challenge of effective health management becomes increasingly prominent. …”
Get full text

Presenting the agility model of the organization in order to improve the productivity of human resources by Asie Mohmedi, Rashid Zolfaghari, Mahsa Gholam hossein zadeh

“…Organizational agility is an organizational capability that must be considered by the managers of educational organizations in order to achieve organizational goals, and has the components of innovation, responsibility, speed in work, low complexity, high quality, flexibility, and readiness to respond to environmental changes, and also is very resistant to environmental problems and challenges (Abolghasem et al., 2018). …”
Get full text

The Circular Kitchen by Bas Jansen

“…However, existing methods do not fully incorporate the complex, multiple use cycles inherent in circular products and components. …”
Get full text

Sustainability Measurement of Farming System in Isfahan Agricultural Sector (Smallholders-Rural Production Cooperatives- Farm Corporation) by Saedali Nekooei Naenii, Yosef Ghanbari, Hamid Barghi

“…Stability measurement is a complex interaction between technology, the environment and society. …”
Get full text

Analysis and Prioritization of Indicators of Urban Development Strategy In the neighborhoods of the eight district of Shiraz by Issa Ebrahimzadeh, Mostafa Istgaldi, Fazel Hajizadeh

“…The statistical population of this study is citizens of four neighborhoods of the neighborhoods of the eight district of Shiraz (N = 24871), which was selected using Cochran formula. 318 people were selected and a proportional to each neighborhood population was distributed randomly in the neighborhood. …”
Get full text

Organising general practice for care homes: a multi-method study by Barbara Hanratty, Rachel Stocker, David Sinclair, Katie Brittain, Karen Spilsbury, Daniel Stow, Louise Robinson, Fiona E Matthews

“…Different structures (e.g. scheduled visits) provide opportunities to develop effective, efficient care, but flounder without established, trusting relationships. …”
Get full text

COOLFACADE by Alejandro Prieto Hoces

“…Increasing cooling needs in the built environment present an important and complex challenge for the design of sustainable buildings and cities. …”
Get full text