Ub-POD: A Ubiquitin-Specific Proximity-Dependent Labeling Technique to Identify E3 Ubiquitin Ligase Substrates in Human Cells by Urbi Mukhopadhyay, Sophie Levantovsky, Christian Behrends, Sagar Bhogaraju

“…Here, we present an efficient protocol that enables the selective biotinylation of substrates of a given ubiquitin ligase. …”
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A novel acidic laminarinase derived from Jermuk hot spring metagenome by Ani Paloyan, Tigran Soghomonyan, Mariam Karapetyan, Hasmik Grigoryan, Anna Krüger, Fiona Cuskin, Jon Marles-Wright, Christin Burkhardt, Garabed Antranikian

“…Abstract Laminarinase, an enzyme with a specific affinity for laminarin—a complex polysaccharide found in the cell walls of brown algae and select marine organisms—was investigated in this study. …”
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Interpersonal and intrapersonal leadership competencies: an interpretative phenomenological analysis on effective leadership strategies by Marion Koreen Andrea Aquino, Alicia Mae Bumacod, Arizzandra Gerriz Calapine, Jan Marie Therese Yaco, Margarett Luz Dimailig, Avon Pearl Amores, Joseph Francisco

“…Effective leadership is critical to organizational success, requiring leaders who can efficiently manage both their tasks and employees. Thus, it is valuable to explore and identify competencies possessed by competent leaders.MethodsThe study utilized an Interpretative Phenomenological Analysis (IPA) approach to have a detailed exploration of the strategies and practices leaders find most effective in navigating complex organizational challenges, such as strategy adoption, teamwork improvement, client relationship management, ethical decision-making, and industry adaptation. …”
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Immunoinformatics-Based development of a Multi-Epitope vaccine candidate targeting coinfection by Klebsiella pneumoniae and Acinetobacter baumannii by Gul Afshan, Namrah Yaseen, Syed H Ali, Asad U. Khan

“…Molecular dynamics (MD) simulations of the vaccine-TLR4 complex predicted a net binding energy of -508.0 kJ/mol, indicating high stability. …”
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MRDDA: a multi-relational graph neural network for drug–disease association prediction by Congzhou Chen, Yaozheng Zhou, Yinghong Li, Jin Xu, Demin Li, Lingfeng Wang

“…Biological entities such as drugs, genes, proteins, RNA, and diseases interact within a complex network. How to adequately extract the intrinsic relationships among them and accurately predict the drug-disease associations remains a challenge. …”
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Spiking Neural Networks for Multimodal Neuroimaging: A Comprehensive Review of Current Trends and the NeuCube Brain-Inspired Architecture by Omar Garcia-Palencia, Justin Fernandez, Vickie Shim, Nicola Kirilov Kasabov, Alan Wang, the Alzheimer’s Disease Neuroimaging Initiative

“…SNNs use discrete spikes for event-driven communication, making them energy-efficient and well suited for the real-time processing of dynamic brain data. …”
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Convolutional neural network-based deep learning for landslide susceptibility mapping in the Bakhtegan watershed by Li Feng, Maosheng Zhang, Yimin Mao, Hao Liu, Chuanbo Yang, Ying Dong, Yaser A. Nanehkaran

“…Abstract Landslides pose a significant threat to infrastructure, ecosystems, and human safety, necessitating accurate and efficient susceptibility assessment methods. Traditional models often struggle to capture the complex spatial dependencies and interactions between geological and environmental factors. …”
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Integrated transmission expansion planning incorporating fault current limiting devices and thyristor-controlled series compensation using meta-heuristic optimization techniques by Abdulaziz Almalaq, Khalid Alqunun, Rabeh Abbassi, Ziad M. Ali, Mohamed M. Refaat, Shady H. E. Abdel Aleem

“…Abstract Transmission expansion planning (TEP) is a vital process of ensuring power systems' reliable and efficient operation. The optimization of TEP is a complex challenge, necessitating the application of mathematical programming techniques and meta-heuristics. …”
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68Ga-labeled fluorinated benzamide derivatives for positron emission tomography imaging of melanoma. by Chaewon Lee, Boreum Song, Eunsu Kim, Yejin Seo, Dagyeong Hong, Jiyu Kim, Wookyeong Jeong, Seong-Young Kwon, Dong-Yeon Kim, Ayoung Pyo

“…The radiochemical yield and radiochemical purity of the 68Ga chelation complex were confirmed by radio-thin layer chromatography (radio TLC). …”
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A Facile Method for Screening DPP IV Inhibitors in Living Cell System Based on Enzyme Activity Probe by Shu-Mei Pan, Chun-Yu Xing, Hong-Wei Li, Rui-Min Wang, Xin-Yue Pu, Tie-Gang Wang, Dan-Dan Wang, Li-Wei Zou

“…Deciphering the relevance of DPP IV to human diseases and screening the inhibitors of DPP IV requires reliable tools, which can sense the function of this key enzyme in complex biological samples. Therefore, we aimed to construct a simple and easy-to-use assay for human DPP IV activity in a living cell system to achieve highly sensitive and selective detection of DPP IV function and further screening for its inhibitors. …”
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Research on the Instability Mechanism and Control Technology of Gob-Side Entry in Deep Mines with Soft Rock by Lu Ma, Luyi Xing, Chang Liu, Tongyuan Cui, Xi Qiao, Wang Miao, Peng Kong

“…The gob-side entry driving in deep mines with soft rock exhibits a complex deformation and instability mechanism. This complexity leads to challenges in roadway stability control which greatly affects the coal mine production succession and safe and efficient mining. …”
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Behçet's syndrome patients' perception of the health system's accountability to care needs: A content analysis study by Neda Sayadi, Simin Jahani, Elham Rajaei

“…Background: Behçet's syndrome (BS) is a chronic, multisystem inflammatory disorder characterized by diverse and complex clinical manifestations, resulting in varied patient care requirements. …”
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A novel interval valued bipolar fuzzy hypersoft topological structures for multi-attribute decision making in the renewable energy sector by Muhammad Imran Harl, Muhammad Saeed, Muhammad Haris Saeed, Muhammad Salman Habib, Seung-June Hwang

“…Also, a novel decision-making algorithm leveraging the presented structure for multi-criteria analysis and complex system modeling is designed. The algorithm is applied to select optimal renewable energy source based on their economic, environmental, and technical aspects. …”
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What can be lost? Genomic perspective on the lipid metabolism of Mucoromycota by Blanka Sokołowska, Małgorzata Orłowska, Alicja Okrasińska, Sebastian Piłsyk, Julia Pawłowska, Anna Muszewska

“…Some strains have been selected as promising biotechnological organisms due to their ability to produce polyunsaturated fatty acids and efficient conversion of nutrients into lipids. …”
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Pharmacists’ Experiences on Adverse Drug Reactions in Saudi Arabia: A Cross-Sectional Study by Dalal Salem Bakheit Aldossari, Naeema Taha Alshalaan, Khuloud Salem Alshammari, Fatima Ahmed Lubbad, Mudhi Ratyan Alanazi, Neamah Ahmed Lubbad, Nada Suliman Fahad Alessa, Sheraz Ali

“…Background and objectives: As part of Vision 2030, Saudi Arabia aims to strengthen its healthcare system by enhancing efficiency, reducing medical errors, and ensuring drug safety. …”
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Unlocking microbiota potential: the role of organic copper in enhancing healthy white shrimp (Penaeus vannamei) farming by Jinzhu Yang, Xiaoyang Yao, Zhonghao Zhang, Gang Lin, Mingzhu Li, Kangsen Mai, Yanjiao Zhang

“…The apparent digestibility coefficients of copper and zinc, along with carbon and nitrogen assimilation, were determined. …”
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Artificial intelligence methods used in various aquaculture applications: A systematic literature review by Thurein Aung, Rafiza Abdul Razak, Adibi Rahiman Bin Md Nor

“…However, the review also uncovered substantial challenges that will continue limiting widespread adoption, including restricted access to representative data, prohibitive expenses, technical complexities, lack of social acceptance, and data privacy and security concerns. …”
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Vowel classification with combining pitch detection and one‐dimensional convolutional neural network based classifier for gender identification by Chia‐Hung Lin, Hsiang‐Yueh Lai, Ping‐Tzan Huang, Pi‐Yun Chen, Chien‐Ming Li

“…The proposed PD‐based extractor and voice classifier could reduce complexity and improve classification efficiency. Acoustic datasets were selected from the Hillenbrand database for experimental tests on 12 vowels classifications, and K‐fold cross‐validations were performed. …”
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PATH PLANNING AND OBSTACLE AVOIDANCE METHODS FOR AUTONOMOUS MOBILE ROBOTS by Ihor Berizka

“…This leads to some complexity in the method but solves typical problems of the classical algorithm, such as local minima, and increases the optimality and smoothness of the path. …”
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Optimizing Remote Sensing Image Retrieval Through a Hybrid Methodology by Sujata Alegavi, Raghvendra Sedamkar

“…Addressing the scaling and rotation variations in image capture, a flexible and dynamic algorithm, modified Deep Image Registration using Dynamic Inlier (IRDI), is introduced for image registration. Given the complexity of remote sensing images, feature extraction occurs at two levels. …”
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