Breaking barriers: targeted delivery of resveratrol in lung cancer using folate-integrated and pH-responsive hybrid nanocarriers by Sanjoy Das, Malay K. Das, Taison Jamatia, Nayan Ranjan Ghose Bishwas, Dhritiman Roy, Emdormi Rymbai

“…Abstract Background Targeting lung cancer while sparing healthy cells is the cornerstone of chemotherapy; however, bioavailability issues and complex biological barriers prevent their accumulation in the tumor sites. …”
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Multidisciplinary DRG management for rational medication in obstetrics: a cost analysis in Zhejiang Province by Qiqin Zhang, Geer Zhang, Shuangneng Yang, Meng Zhang, Shujuan Shu, Mengdan Zhao

“…Conclusions The research findings show that early pharmacist involvement in the multidisciplinary team management has positively impacted hospital functioning, including quality, efficiency, and costs. It identifies pharmaceutical costs as the main adjustable expenditure in OZ13 disease group and highlights the necessity of differentiated management for complex cases.…”
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Unsupervised Cross-Domain Polarimetric Synthetic Aperture Radar (PolSAR) Change Monitoring Based on Limited-Label Transfer Learning and Vision Transformer by Xinyue Zhang, Rong Gui, Jun Hu, Jinghui Zhang, Lihuan Tan, Xixi Zhang

“…Accurate labels and supervised models are difficult to reuse between massive unlabeled time-series PolSAR data due to the complex distribution shifts caused by different imaging parameters, scene changes, and random noises. …”
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Network characteristics of comorbid symptoms in alcohol use disorder by Xin Yu, Wen Zhang, Can Wang, Guolin Mi, Xiuzhe Chen, Yanhu Wang, Xu Chen

“…This study aims to analyze comorbidities and their complex relationships in AUD patients through epidemiological surveys and network analysis.Materials and methods Using multi-stage stratified cluster random sampling, we selected 27,913 individuals and identified those with AUD for the study. …”
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GaitCSF: Multi-Modal Gait Recognition Network Based on Channel Shuffle Regulation and Spatial-Frequency Joint Learning by Siwei Wei, Xiangyuan Xu, Dewen Liu, Chunzhi Wang, Lingyu Yan, Wangyu Wu

“…However, existing gait recognition methods predominantly rely on single-modal data, which demonstrates insufficient feature expression capabilities when confronted with complex factors in real-world environments, including viewpoint variations, clothing differences, occlusion problems, and illumination changes. …”
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Development of a core outcome set for pharmacological interventions in osteoporosis among patients with diabetes mellitus: an international consensus study protocol by Chao Wei, Chao Wei, Xiaobin Wang, Zubing Mei, Zubing Mei, Jing Li

“…Patients with DM are at increased risk of developing osteoporosis due to complex pathophysiological interactions between glucose metabolism and bone health. …”
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Overexpression of miRNA29a gene inhibits proliferation and promotes apoptosis of jejunal epithelial cells in yak by Jianlei Jia, Erwei Zuo, Ning Li, Siyuan Kong, Pengjia Bao, Qian Chen, Ping Yan

“…Interestingly, GPR41, as a bridge protein, was contacted two predominant themes to involved in Pamir Yaks jejunal mechanical barrier PPI network, and the target proteins displayed strong mutual interactions in the complex PPI network. Overall, our study suggested that the over-expression miR-29a inhibited the jejunal epithelial cells proliferation and the expressions of specific proteins, which damaged jejunal barrier function to slow down the intestine structure and function advanced mature development during young livestock period for influence the enhanced performance of production efficiency.…”
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The large language model diagnoses tuberculous pleural effusion in pleural effusion patients through clinical feature landscapes by Chaoling Wu, Wanyi Liu, Pengfei Mei, Yunyun Liu, Jian Cai, Lu Liu, Juan Wang, Xuefeng Ling, Mingxue Wang, Yuanyuan Cheng, Manbi He, Qin He, Qi He, Xiaoliang Yuan, Jianlin Tong

“…By highlighting the advantages of LLMs in handling complex clinical data, identifying interrelationships between features, and improving diagnostic accuracy, this study seeks to provide a more efficient and precise solution for the early diagnosis of TPE. …”
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Mythology Study and Comparison for Quadratic DC-DC Step-up Converters by ZAHRAA TALIB

“…Alongside the primary aims of its use, the researcher must address the practical aspects of the suggested approach, including duty cycle operational range, output voltage fluctuations, reduction of component consumption, cost, and complexity. This article examines and compares quadratic step-up converter topologies from recent years, highlighting researchers' endeavours to attain high voltage transfer gain, regulated output, and efficiency. …”
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NMR Relaxation to Probe Zeolites: Mobility of Adsorbed Molecules, Surface Acidity, Pore Size Distribution and Connectivity by Marina G. Shelyapina

“…Recent studies have shown that mesoporosity is beneficial to the rational design of catalysts with controlled product selectivity and an improved catalyst lifetime due to its efficient mass-transport properties. …”
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Design and Development of a Novel Universal Gripper Having Rigid Mechanics With Self-Adaptable Fingers for Industrial Applications by Muhammad Usman Khalid, Michal Jilich, Mattia Frascio, Benoit Levesque, Alessandro Zanella, Matteo Zoppi

“…In industrial assembly, intralogistics, and powertrain automation, it is essential to implement robust, safe, and efficient object-grasping solutions that are applicable to various scenarios. …”
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Molecular activity of bioactive phytocompounds for inhibiting host cell attachment and membrane fusion interacting with West Nile Virus envelope glycoprotein. by Noimul Hasan Siddiquee, Shanjida Akter Joyoti, Bushra Binte Zaker, Mansura Akter Eva, Alif Islam Nava, Nusrat Jahan Mridu, Al Amin Shawon, Sanjida Rahman, Tasnuva Jamil Chowdhury, Susmita Sarkar Katha, Md Rafiul Islam, Mohammad Sharif Uddin

“…The selected compounds are secure and efficient since they demonstrate excellent toxicological and Pk characteristics. …”
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UNCERTAINTY, CHANGEABILITY AND INCONSISTENCY IN TASKS OF ANALYZING RISKS OF ECONOMIC SYSTEM BEHAVIOR by V. I. Avdiyskiy, V. М. Bezdenezhnyh

“…The theorem of ultimate uncertainty of a complex economic system states that the social-economical process of a complex economic system functioning develops efficiently if complexity and manageability characteristics are similar, and manageability criteria correspond to the levels of uncertainty of the environment and organization, and subsequently, its risk levels and management systems. …”
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Artificial intelligence driven 3D reconstruction for enhanced lung surgery planning by Xiuyuan Chen, Chenyang Dai, Muyun Peng, Dawei Wang, Xizhao Sui, Liang Duan, Xiang Wang, Xun Wang, Wenhan Weng, Shaodong Wang, Heng Zhao, Zhenfan Wang, Jiayi Geng, Chen Chen, Yan Hu, Qikang Hu, Chao Jiang, Hui Zheng, Yi Bao, Chao Sun, Zhuoer Cui, Xiangyu Zeng, Huiming Han, Chen Xia, Jinlong Liu, Bing Yang, Ji Qi, Fanghang Ji, Shaokang Wang, Nan Hong, Jun Wang, Kezhong Chen, Yuming Zhu, Fenglei Yu, Fan Yang

“…Abstract The increasing complexity of lung surgeries necessitates the need for enhanced imaging support to improve the precision and efficiency of preoperative planning. …”
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Innovations and income inequalities – a comparative study by Julia Włodarczyk

“…This paper presents a regression analysis based on the selected measures of innovativeness (gross domestic expenditure on R&D, number of patent applications, the Creative Economy Index), income inequalities (Gini coefficient, top 3% and top 1% shares of national equalized income) and various control variables retrieved mostly from the Eurostat Database for 30 countries (European Union countries, Iceland, Norway) for the study period of 2005-2014. …”
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The Hub Location and Flow Assignment Problem in the Intermodal Express Network of High-Speed Railways and Highways by Xiaoting Shang, Zhenghang Wang, Xin Cheng, Xiaoyun Tian

“…Considering the characteristics of multiple modes, flow balance, carbon emission, capacity constraints, and time constraints in the intermodal express network, a mixed-integer linear programming model is proposed with the objective of minimizing the total cost by determining the hub locations, allocations, mode selections, and flow assignments. Owing to the NP-hard computational complexity, an improved genetic algorithm with local search is designed by combining the genetic operators and two optimization strategies to solve the problem effectively. …”
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Determination of malachite green in sediment by ultra performance liquid chromatography-mass spectrometry by Mei Guangming, Guo Yuanming, Zhang Xiaojun, Yan Zhongyong, Li Peipei, You Juju, Ding Yueping

“…The current researches mainly focus on the determination of MG in aquatic products, rarely in sediment. Due to the matrix complex of sediment, sample pretreatment technology is the key technology. …”
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Trajectory optimization of a flapping-wing robot in a wind field by Xiaoyang WU, Zhiguo ZHANG, Wei HE, Jingyan QIN, Junhai ZHANG, Tingting MENG

“…On the sea surface, albatrosses exploit this gradient wind field to glide efficiently, enabling them to fly thousands of kilometers using wind energy. …”
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Hydraulic-thermal decoupling simulation model for transient operation of natural gas pipeline networks by Chunyu YU, Chunhao YU, Gang LIU, Rui LIU, Fang YANG, Yang QIN, Lili ZUO, Qian CHEN

“…Currently, the primary challenge in transient operation simulation technology for natural gas pipeline networks is the complexity of the nonlinear coupling of spatial and temporal variables, making it urgent to enhance the calculation efficiency of the simulation process. …”
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Integration of ordered porous materials for targeted three-component gas separation by Xue Jiang, Yu Wang, Hui Wang, Lu Cheng, Jian-Wei Cao, Jin-Bo Wang, Rong Yang, Dong-Hui Zhang, Run-Ye Zhang, Xiu-Bo Yang, Su-Hang Wang, Qiu-Yu Zhang, Kai-Jie Chen

“…Abstract Separation of multi-component mixtures in an energy-efficient manner has important practical impact in chemical industry but is highly challenging. …”
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