RNA toehold switch-based reporter assay to assess bacterial uptake of antisense oligomers by Paramita Sarkar, Linda Popella, Sandra Pérez-Jiménez, Jörg Vogel

“…However, their efficient delivery across the complex bacterial envelope remains a major challenge. …”
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Urban Hierarchy Migration Model and Impact Mechanism of Graduates Admitted to the Guangdong Provincial Civil Service Examination by Wu Jinghao, Liu Ye, Tang Honglin

“…The decision-making and selection process in the selection mechanism for the migration mode of newly recruited graduates in the civil service examination is complex and dynamic, involving the interaction of multiple factors, such as government policy guidance, job characteristics, personal factors, and urban conditions, with objective limitations, personal abilities and resources, and subjective willingness. …”
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Research progress,key scientific issues,and prospects of segmented fracturing and pressure relief gas drainage technology for coal seam roof horizontal wells by Ke YANG, Zhainan ZHANG, Xinzhu HUA, Wenjie LIU, Xin LYU, Xiaolou CHI, Changcheng WANG, Caiqing LI

“…The segmented fracturing and pressure relief gas drainage technology in the horizontal well of the coal seam roof is a key means to guide the efficient gas extraction in deep, high gas, soft and low permeability coal seams.Based on this, a full lifecycle development concept for the segmented fracturing, pressure relief,and gas drainage engineering of the coal seam roof horizontal well is proposed, including three stages: early scientific planning, mid-term engineering construction, and later safety management.This paper summarizes the research progress on the full life cycle development of segmented fracturing and pressure relief gas drainage in coal seam roof horizontal wells, constructs an overall research framework for key scientific issues related to segmented fracturing and pressure relief gas drainage in coal seam roof horizontal wells, and looks forward to its future development direction.The results show that the expansion of segmented fracturing cracks in the horizontal well of the coal seam roof is extremely complex due to geological factors, construction parameters, and physical properties.It is urgent to comprehensively evaluate the primary and secondary relationships under the influence of multiple factors in crack expansion, and reveal the mechanism of coal seam roof fracturing crack expansion under the influence of multiple factors.Exploring the critical relationship between the coupling of stress, water, temperature, and coal factors on the promotion and inhibition of coalbed methane adsorption, desorption, and migration, and establishing an optimal model for coalbed methane adsorption and desorption under multiple critical indicators, is the key to achieving efficient coalbed methane extraction. …”
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Development of the clinical trial site performance metrics instrument: A study protocol by Mattia Bozzetti, Rosario Caruso, Silvia Soncini, Monica Guberti

“…Clinical trials (CTs) are essential for medical advancements, yet their increasing complexity and cost demand improved efficiency in trial management. …”
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Large-Scale Demand Driven Design of a Customized Bus Network: A Methodological Framework and Beijing Case Study by Jihui Ma, Yang Yang, Wei Guan, Fei Wang, Tao Liu, Wenyuan Tu, Cuiying Song

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Evaluation of empirical relationships in carbonates by developing a 1D mechanical earth model in an oil field in Southwestern Iran by Hadi Ammarloo, Pedram Zoughy, Leili Fatahi Mehraban, Mohammadkazem Amiri

“…Accurate determination of rock mechanical parameters is crucial for safe and efficient drilling, production, and reservoir development in these complex formations. …”
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A review of eDNA technology in avian monitoring: Current status, challenges and future perspectives by Ying Ke, Tong Liu, Chenglong Han, Xue Yu, Jinmei Wang, Laixing Ding, Hongliang Pan, Xunqiang Mo, Xueqiang Lu

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Key Generation in Cryptography Using Elliptic-Curve Cryptography and Genetic Algorithm by Sanjay Kumar, Deepmala Sharma

“…The study evaluates the efficiency and effectiveness of the proposed ECC-GA approach through an empirical analysis of execution time, key size, and the size of the search space. …”
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Diff-Pre: A Diffusion Framework for Trajectory Prediction by Yijie Liu, Chengjie Zhu, Xin Chang, Xinyu Xi, Che Liu, Yanli Xu

“…An intention module regulates lateral offsets, and the diffusion framework selects the most probable trajectory from various possible predictions, thereby improving the model’s ability to handle complex scenarios. …”
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On-Chip Purification of Extracellular Vesicles for microRNA Biomarker Analysis by Cristina Potrich, Anna Pedrotti, Lia Vanzetti, Cecilia Pederzolli, Lorenzo Lunelli

“…Here, microparticles with surfaces endowed with positive ions were exploited to separate vesicles from complex biological matrices. First, flat silicon oxide surfaces functionalized with different divalent cations were tested for their efficiency in terms of small EV capture. …”
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Meta-transformer: leveraging metaheuristic algorithms for agricultural commodity price forecasting by G. H. Harish Nayak, Md. Wasi Alam, B. Samuel Naik, B. S. Varshini, G. Avinash, Rajeev Ranjan Kumar, Mrinmoy Ray, K. N. Singh

“…Abstract Predicting agricultural commodity prices is inherently complex due to factors such as perishability, seasonality, and market volatility. …”
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Automated System for Evaluating Alternatives for Developing Innovative IT Projects by Iryna Pikh, Vsevolod Senkivskyy, Liubomyr Sikora, Nataliia Lysa, Alona Kudriashova

“…The key result of the research is the created software product that allows one to automate the procedure for selecting the optimal solution for the IT project development process, providing reliable support for simulation modeling and increasing the efficiency of project management. …”
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Artificial intelligence in geoenergy: bridging petroleum engineering and future-oriented applications by Sungil Kim, Tea-Woo Kim, Suryeom Jo

“…Future research should focus on developing automated, user-independent AI systems to enhance model selection and broaden AI applications across diverse datasets, driving greater efficiency and innovation in the geoenergy sector. …”
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A critical review of optimizing pollutant removal from refinery wastewater using ozone and nanocatalyst-assisted bubble column reactors by Safiaa M. Mohammed, Khalid A. Sukkar, Ali Abdul Rahman Al-Ezzi, Amjed R. Qarahgouli

“…The treatment of petroleum refinery wastewater remains a critical challenge due to the complex mixture of toxic and persistent contaminants such as hydrocarbons, phenolic compounds, nitrogenous substances, and heavy metals. …”
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Advancing Pediatric Growth Assessment with Machine Learning: Overcoming Challenges in Early Diagnosis and Monitoring by Mauro Rodriguez-Marin, Luis Gustavo Orozco-Alatorre

“…Logistic regression is a reliable and easily interpretable model for detecting growth abnormalities in children. Unlike complex machine learning models, it offers parsimony in transparency, efficiency, and reproducibility, making it ideal for clinical settings where explainable, data-driven decisions are essential. …”
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ATTRN: Acoustic Information Encoder and Temperature Field Reconstruction Decoder Network for Boiler Temperature Field Reconstruction by Kunyu Wu, Keqi Ni, Liwei Chen, Hengyuan Xu, Junqiao Wang, Jingyi Zhou, Xinzhi Zhou

“…The proposed approach avoids complex traditional mathematical processing and empirical parameter selection, enhancing both accuracy and generalization. …”
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Hybridization in Metal Wire Additive Manufacturing: A Case Study of an Impeller by Shahu R. Karade, Siddhartha Siddhartha, Neel Kamal Gupta, Ganesan G, K. P. Karunakaran, Henning Zeidler

“…This demonstrates a more efficient, precise, and cost-effective method to optimize metal wire AM for producing complex metal components, advancing capabilities and applications.…”
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Iron-catalyzed alkyne alkylzincation affected by counterions by Lu-Jie Li, Qiao Zhang, Peng He, Ming-Yao Huang, Shou-Fei Zhu

“…Abstract Metal complex catalysts typically comprise three components: ligands, central metals, and counterions. …”
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Development of Automatic Welding System for Offshore Platform Pile Pipe by XU Jia-zhong, ZHANG Yu, YOU Bo, LI Dong-jie, FU Wei

“…Twin arc welding system for offshore platform pile pipe with multipoint dual power and a single molten pool is put forward in this paper in order to solve the problems of low producing efficiency and operating inconvenience in complex environment. …”
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Spatial analysis of contact deformation, stiffness, and flash temperature in involute gear pairs by Hongtao Dong, Hongtao Dong, Yang Zhang, Lixin Xu

“…Gear contact behavior significantly influences system vibration, wear, and transmission efficiency. Among the factors governing this, contact deformation, flash temperature, and meshing stiffness are particularly critical. …”
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