Possibilities of a software-based hybrid single photon emission computed tomography/ magnetic resonance imaging in the diagnosis of complicated diabetic foot syndrome by V. D. Zavadovskaya, M. A. Zorkal’tsev, V. D. Udodov, M. A. Zamyshevskaya, O. Yu. Kilina, A. P. Kurazhov, K. M. Popov

“…The FP results were due to the low resolution of the technique and to the small sizes of the object under study. …”
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Rapid Prediction of Multi-physics Coupling in Heat Pipe ReactorBased on Neural Network by ZHANG Junda, LIU Xiaojing, XIONG Jinbiao, CHAI Xiang, ZHANG Tengfei

“…By deploying one or multiple neural network models as substitutes, this methodology not only sustains the scalability inherent to rapid predictive schemes but also attenuates the complexity associated with the neural network’s surrogate functionalities. …”

Comparative efficacy of modified Shiraki procedure and pedicled Island preputial flap in the treatment of severe concealed penis in children by Rifang Pan, Junzhong Li, Zhaowei Zhou, Kunlan Liang, Zhaopan Li, Zhihua Xiao

“…The former is characterized by shorter, simpler operations, while the latter offers better cosmetic outcomes despite its complexity.…”
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A Case Report of Pediatric Abdominal Tuberculosis with Intestinal Perforation Misdiagnosed as Malignancy by Tong M, Ding W, Wu H, Yuan L, Ma X, Yang X, Wang Y, Luo Y

“…After clinical improvement, oral anti-TB therapy was initiated, leading to significant resolution of abdominal pathology.Conclusion: This case highlights the diagnostic complexity of pediatric abdominal TB, particularly when presenting with an abdominal mass complicated by intestinal perforation. …”
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Clinical and Genetic Spectrum of Nine Cases of NLRP3-Associated Autoinflammatory Disease (NLRP3-AID) and Identification of One Novel NLRP3 Mutation by Genetic Variation Analyses by Yaoyao Shangguan, Xingru Ding, Le Ma, Yi-Xin Cai, Shulei Xiang, Xiu-Feng Huang, Yunyan Shen, Hai-Guo Yu, Wenjie Zheng

“…Genetic heterogeneity, including a novel mutation, highlighted the complexity of NLRP3-AID in this population.…”
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A large pedunculated subserosal myoma with cystic and red degeneration: A case report with literature review by Siham Oukassem, Chaimae Abourak, Asmae Guennouni, Lina Belkouchi, Nazik Allali, Latifa Chat, Siham El Haddad, Khaoula Laaboud, Samia Bennaceur, Nada Douraidi, Maakoul Rachid, Zaki El Hanchi

“…We report a clinical case that underscores this diagnostic complexity and emphasizes the importance of a multidisciplinary approach, integrating advanced imaging modalities to establish an accurate diagnosis.…”
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Light scattering and microphysical properties of atmospheric bullet rosette ice crystals by S. W. Wagner, S. W. Wagner, M. Schnaiter, M. Schnaiter, M. Schnaiter, G. Xu, G. Xu, F. Rogge, F. Rogge, E. Järvinen, E. Järvinen

“…Bullet rosette stereo images are analyzed for their microphysical properties, including maximum dimension, bullet aspect ratio, number of bullets, projected area, bullet hollowness, derived mass, derived effective density, and derived terminal velocity, as well as their optical properties such as <span class="inline-formula"><i>g</i></span> and the optical complexity parameter. Results indicate that much lower <span class="inline-formula"><i>g</i></span> values represent real atmospheric bullet rosette crystals than what is expected by numerical calculations assuming solid or hollow bullets, indicating higher levels of crystal complexity than have been incorporated within previous bullet rosette ray-tracing studies. …”
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Multi-cancer early detection tests for general population screening: a systematic literature review by Ros Wade, Sarah Nevitt, Yiwen Liu, Melissa Harden, Claire Khouja, Gary Raine, Rachel Churchill, Sofia Dias

“…Limitations Study selection was complex; it was often difficult to determine the stage of development of multi-cancer early detection tests. …”
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Structural insights into the binding modes of lanreotide and pasireotide with somatostatin receptor 1 by Zicheng Zeng, Qiwen Liao, Shiyi Gan, Xinyu Li, Tiantian Xiong, Lezhi Xu, Dan Li, Yunlu Jiang, Jing Chen, Richard Ye, Yang Du, Thiansze Wong

“…This study presents high-resolution cryo-electron microscopy structures of SSTR1 complexed with Lan or Pas, revealing the distinct mechanisms of ligand-binding and activation. …”
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Improving predictive accuracy in multiple myeloma using a plasma cell profile derived from single-cell RNA sequencing by Lanting Liu, Hao Sun, Fangshuo Feng, Xiyue Sun, Jingyuan Ma, Rui Lv, Tengteng Yu, Linhai Ye, Xiuchun Li, Zhen Yu, Xiaoyu Zhang, Huaqing Jing, Yao Yao, Fengxia Ma, Lugui Qiu, Mu Hao

“… Multiple myeloma (MM) shows inherent clinical and biological heterogeneity, leading to variable treatment responses and outcomes. The complex molecular landscape of MM makes precise risk stratification through clinical genetic testing difficult. …”
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Efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis: a protocol for a multicentre, randomised, parallel... by José Antonio Pinto, Alex Fonollosa, Ester Carreño, Maria Isabel Rodriguez, David Diaz-Valle, Diana Peiteado, Luis Rodriguez-Rodriguez, Miguel Cordero-Coma, Marta Tejera Santana, Lidia Cocho, Ana Belen Rivas, Amanda Lopez-Picado, Valentina Calamia, Felix M Francisco Hernandez, Angel Garcia-Aparicio, Javier Garcia-Gonzalez, Jose Juan Mondejar, Leticia Lojo-Oliveira, Llucí Martínez-Costa, Santiago Munoz, Beatriz Rodriguez-Lozano, Esperanza Pato, Elena Molina, Luis Alberto Tebar, Mara Albert Fort, Mayte Ariño Gutierrez, Pedro Arriola Villalobos, Joseba Artaraz Beobide, Antonio Atanes Sandoval, Jose Manuel Sanchez, Francisco Blázquez, Pablo Borges Deniz, Lara Borrego Sanz, Gabriela Bustamante Sanchez-Arnedo, Bruno Casco Silva, Ricardo Cuiña Sardiña, Almudena De Pablo Cabrera, Maria Del Mar Esteban Ortega, Patricia Fernandez Puente, Dalifer Dayanira Nuñez, Javier Garcia Bella, Sara Garcia Carazo, Luis Garcia Onrubia, Jose Maria Morales, Jose Antonio Fernandez, Vanesa Hernandez Hernandez, Inés Hernanz Rodriguez, Jose Maria Cantalapiedra, Ventura Hidalgo Barrero, Maria De Jovani Casano, Sara López Sierra, Virginia Lozano Lopez, Alfredo Madrid Garcia, Rosalia Mendez Fernandez, Pilar Nozal Aranda, Eugenio Perez Blazquez, Chamaida Plasencia Rodriguez, Sheila Recuero Diaz, Ignacio Robles Barrena, Esther Rodriguez Almaraz, Fayna Maria Gonzalez, Guadalupe Rodriguez Martinez, Fredeswinda Isabel Bueno, Ioana Ruiz Arruza, Beatriz Sanchez Marugan, Olga Sanchez Pernaute, Armelle Schlinker Giraud, Alvaro Seijas Lopez, Patricia Simon Alonso, Elia Valls Pascual

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Bidirectional effect modifications of temperature and PM2.5 on myocardial infarction morbidity and mortality in Beijing, China from 2007 to 2021 by Piaopiao Hu, Qinghui Zeng, Jie Chang, Moning Guo, Feng Lu, Yue Qi, Zhao Yang, Pingping Jia, Qiuju Deng, Jing Liu

“…Background: Ambient temperatures and PM2.5 can trigger myocardial infarction (MI), while little is known about the complex interplay between these two factors on MI, especially morbidity. …”
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FEAST: Probing the Stellar Population of the Starburst Dwarf Galaxy NGC 4449 with JWST/NIRCam by Matteo Correnti, Giacomo Bortolini, Flavia Dell’Agli, Angela Adamo, Michele Cignoni, Elena Sacchi, Monica Tosi, Alex Pedrini, Anne S. M. Buckner, Daniela Calzetti, Ana Duarte-Cabral, Bruce G. Elmegreen, Helena Faustino Vieira, John S. Gallagher, Kathryn Grasha, Benjamin Gregg, Kelsey E. Johnson, Thomas S.-Y. Lai, Drew Lapeer, Sean T. Linden, Matteo Messa, Goran Ostlin, Elena Sabbi, Linda J. Smith, Paolo Ventura

“…These results confirm NGC 4449's status as a compelling example of a local dwarf starburst galaxy undergoing complex and possibly externally driven star formation and underscore the power of JWST in probing the full lifecycle of stars in nearby starburst systems.…”
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Deep metabolic profiling of immune cells by spectral flow cytometry—A comprehensive validation approach by Claire L. Wishart, Alanna G. Spiteri, Jian Tan, Claudio Counoupas, James A. Triccas, Laurence Macia, Nicholas J.C. King

“…This standardized approach reduces cost and experimental complexity, enabling researchers to elucidate how metabolism drives immune function across broader immunological and clinical contexts.…”
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L’enfant et la ville : deux exemples de bandes dessinées tout public (1992-2020) by Martine Motard-Noar

“…The article is an analysis of the complexity of the representation of children in the city in the two series. …”
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Fluid drawing printing 3D conductive structures for flexible circuit manufacturing by Yikang Li, Dazhi Wang, Yiwen Feng, Xiangji Chen, Xu Chen, Chang Liu, Yanteng Li, Liujia Suo, Ran Zhang, Xiaopeng Zhang, Ben Liu, Fengshu Wang, Shiwen Liang, Lingjie Kong, Qiang Fu, Tongqun Ren, Tiesheng Wang

“…The printing resolution is, however, highly dependent on the needle size. …”
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Psychiatric neuroimaging at a crossroads: Insights from psychiatric genetics by Lorenza Dall’Aglio, Saúl Urbina Johanson, Travis Mallard, Sander Lamballais, Scott Delaney, Jordan W. Smoller, Ryan L. Muetzel, Henning Tiemeier

“…Thanks to methodological advances, large-scale data collections, and longitudinal designs, psychiatric neuroimaging is better equipped than ever to identify the neurobiological underpinnings of youth mental health problems. However, the complexity of such endeavors has become increasingly evident, as the field has been confronted by limited clinical relevance, inconsistent results, and small effect sizes. …”
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Harmonizing remote sensing and ground data for forest aboveground biomass estimation by Ying Su, Zhifeng Wu, Xiaoman Zheng, Yue Qiu, Zhuo Ma, Yin Ren, Yanfeng Bai

“…Accurate aboveground biomass (AGB) estimation is crucial for evaluating management and conservation policy of forests. However, the complexity of forest ecosystems and the diversity of geography bring great challenges to traditional biomass estimation methods. …”
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Epigenetic control of topoisomerase 1 activity presents a cancer vulnerability by Tae-Hee Lee, Colina X. Qiao, Vladislav Kuzin, Yuepeng Shi, Marina Farkas, Zhiyan Zhao, Vijayalalitha Ramanarayanan, Tongyu Wu, Tianyi Guan, Xianzhen Zhou, David Corujo, Marcus Buschbeck, Laura Baranello, Philipp Oberdoerffer

“…While topoisomerase 1 (TOP1) activity is essential for DNA supercoil removal, the aberrant stabilization of TOP1:DNA cleavage complexes (TOP1ccs) can result in cytotoxic DNA lesions. …”
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Dramatic Enhancement of Macrozoobenthic Species β-Diversity in Response to Artificial Breakwater Construction Along a Tropical Coastline by Huan Chiao Lee, Christopher J. Glasby, Anja Schulze, Han Raven, Siong Kiat Tan, Takaomi Arai, Amirah Md Jin, Nurun Nazihah Tal’ah, Ainina Zarifi, David J. Marshall

“…We compared habitat complexities and species assemblages among artificial breakwater shores (ABS), a natural rocky shore (NS), and an embayment shore (ES). …”
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