Landscape of informed consent practices and challenges in point‐of‐care clinical trials by Caleigh Propes, Trevan Locke, Rachele Hendricks‐Sturrup

“…Steps should be taken to establish ethical standards for point‐of‐care trials that reflect and serve the best interests of patients while reducing administrative burden and complexity. …”
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Deep Reinforcement Learning for Dynamic Pricing and Ordering Policies in Perishable Inventory Management by Yusuke Nomura, Ziang Liu, Tatsushi Nishi

“…To solve this problem more efficiently, we also implement a deep reinforcement learning algorithm, proximal policy optimization, to solve this problem. …”
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Sign-Entropy Regularization for Personalized Federated Learning by Koffka Khan

“…Motivated by Descartes’ Rule of Signs, we hypothesize that frequent sign changes in gradient trajectories reflect complexity in the local loss landscape. By minimizing the entropy of gradient sign patterns during local updates, SER encourages smoother optimization paths, improves convergence stability, and enhances personalization. …”
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Advanced ecosystem restoration: Blending phytoremediation with satellite-based imagery with remote sensing in the Himalayas of PIN Valley National Park, India by A. Galodha, D. Sharma, J. Verma

“…Despite challenges, such as spectral complexity and atmospheric variability, spectral data delineates metal-induced stress markers in vegetation, underscoring phytoremediation's potential. …”
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Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early by Mariangela Morelli, Francesca Lessi, Serena Barachini, Serena Barachini, Romano Liotti, Romano Liotti, Nicola Montemurro, Paolo Perrini, Orazio Santo Santonocito, Carlo Gambacciani, Matija Snuderl, Francesco Pieri, Filippo Aquila, Azzurra Farnesi, Antonio Giuseppe Naccarato, Paolo Viacava, Francesco Cardarelli, Gianmarco Ferri, Gianmarco Ferri, Paul Mulholland, Diego Ottaviani, Fabiola Paiar, Gaetano Liberti, Francesco Pasqualetti, Francesco Pasqualetti, Michele Menicagli, Paolo Aretini, Giovanni Signore, Sara Franceschi, Chiara Maria Mazzanti

“…This therapeutic standstill is primarily due to preclinical approaches that do not fully respect the complexity of GB cell biology and fail to test efficiently anti-cancer treatments. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…This differential training may have been reflected in the greater confidence of pharmacists to risk stratify and de-label patients. …”
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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…Crisis standards of care, used when healthcare capacity becomes overwhelmed and cannot meet regular standards of patient care, reflect ethical priorities relevant in times of shortage or other emergencies. …”
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