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4321
Tumor microenvironment responsive Mn-based nanoplatform activate cGAS-STING pathway combined with metabolic interference for enhanced anti-tumor therapy
Published 2025-05-01“…Abstract Despite the encouraging developments in tumor immunotherapy, the complex tumor microenvironment (TME) and abnormal energy metabolism persist as key factors facilitating immune escape. …”
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4322
OCT-Angiography in Early Choroidal Melanoma and Choroidal Nevi
Published 2020-09-01“…We diagnosed homogeneous isoreflective choriocapillaries similar in brightness to the surrounding vessels in all 45 patients with benign nevi.Conclusions. Thus, the complex of clinical and instrumental methods, including OCTA, makes it possible to establish the diagnosis of malignant tumor of the choroid in early stages. …”
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4323
A novel image fusion method based on UAV and Sentinel-2 for environmental monitoring
Published 2025-07-01“…Second, a two-layer preprocessing approach is applied to enhance data quality. …”
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4324
Crayfish optimization based pixel selection using block scrambling based encryption for secure cloud computing environment
Published 2025-01-01“…Traditional encryption algorithms are often inadequate in protecting confidential data, especially digital images, from complex cyberattacks. The increasing reliance on cloud storage and transmission of digital images has made it essential to develop strong security measures to stop unauthorized access and guarantee the integrity of sensitive information. …”
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4325
Disposable in-tip cellulose paper device functionalized with clove essential oil for green and efficient extraction of abusable prescription drugs
Published 2025-05-01“…Furthermore, the protocol achieved a click analytical chemistry index (CACI) score of 85 and a ComplexMoGAPI score of 83, highlighting its outstanding greenness, simplicity, and field-deployability for forensic and toxicological applications.…”
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4326
Technology and Application Development of Medical Foundation Model
Published 2024-12-01“…The technology system is composed of a base layer, a model layer, an application layer, and a common module. …”
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4327
Magnetically sensitive nanocomposites for targeted antitumor therapy with application of gemcitabine
Published 2020-11-01“…The thickness of the adsorbed layer of GEM in the composition of Fe3O4@GEM NC was determined by magnetic granulometry. …”
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4328
Representation Learning of Multi-Spectral Earth Observation Time Series and Evaluation for Crop Type Classification
Published 2025-01-01“…The proposed methodology includes a set of single-layer AEs with a very limited number of neurons, each one trained with the mono-temporal spectral features of a small set of samples belonging to a class, resulting in a model capable of processing very large areas in a short computational time. …”
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4329
Single-Stage Pedicle Preputial Tube Substitution Urethroplasty with Corpora Cavernosa Augmentation Using Buccal Mucosa Graft for Primary Peno-Scrotal Hypospadias Repair in Adults
Published 2025-07-01“…This may also have consequences on the complexity of surgical repair (1), given that ventral chordee can alter penile development, leading to a higher degree of corporal fibrosis and consequently a more severe ventral curvature. …”
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4330
Migration of ferrous ions (Fe2+) during the synthesis of (Li,Fe)OHFeSe by ion exchange technology
Published 2025-01-01“…Iron-based superconductors (FeSCs), particularly the air-stable (Li,Fe)OHFeSe, have drawn considerable attention due to their complex crystalline structures and intriguing superconducting properties. …”
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4331
Application of audio frequency magnetotelluric 3D prospecting in a hot area exploration
Published 2025-03-01“…To determine the spatial distribution characteristics of heat storage, cover layer, and heat conduction channel of a geothermal system located in a hot spring area with clear geothermal geological characteristics. …”
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4332
Finite Element Analysis of the Effects of Different Shapes of Adult Cranial Sutures on Their Mechanical Behavior
Published 2025-03-01“…Based on the different morphologies of the cranial sutures, six groups of finite element models (closed, straight, sine wave, tight sinusoidal wave, layered sinusoidal wave, and layered sinusoidal wave + sutural bone) of the bone–suture–bone composite structures that ranged from simple to complex were constructed. …”
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4333
Research on the basic theory and application of enhanced recovery in tight sandstone gas reservoirs
Published 2025-01-01“…Enhancing the recovery rate of tight sandstone gas reservoirs is a complex engineering challenge that necessitates thorough, refined, and systematic research into its fundamental theories. …”
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4334
Association between retinal markers and cognition in older adults: a systematic review
Published 2022-06-01“…Optical coherence tomography (OCT) was the most commonly used retinal scanning methodology to measure the thickness of retinal nerve fibre layer, the ganglion cell complex, choroid and macula. 51.1% of cross-sectional studies using OCT reported an association between the thinning of at least one retinal parameter and poor cognition. …”
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4335
Seismicity characteristics and interseismic locking of the Anninghe Fault, Southwest China: Insights from long-term dense seismic array observations
Published 2025-05-01“…The seismogenic layer depth of the Anninghe Fault is constrained to be less than 15 km, whereas the Daliangshan Fault had a notably deeper seismogenic layer, ranging from roughly 20 to 30 km in depth. …”
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4336
Emergence of sliding ferroelectricity in naturally parallel-stacked multilayer ReSe2 semiconductor
Published 2025-07-01“…However, traditional sliding ferroelectrics typically require complex artificial stacking to break symmetry, and most of them lack atomic-scale evidence. …”
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4337
Preserving fruit freshness with amyloid-like protein coatings
Published 2025-05-01“…Abstract Addressing critical challenges in perishable fruit preservation, including hydrophobic surface treatment, protective layer adhesion on complex cuticles, and synergistic integration of preservation components, here we present an eco-friendly amyloid-like protein coating strategy developed through computer-aided molecular simulation. …”
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4338
Recent developments in coatings on biodegradable Mg alloys: A review
Published 2025-04-01“…This review analyzes and summarizes the most recent developments in popular coating technologies, including micro-arc oxidation, electrophoretic deposition, chemical conversion, anodic oxidation, layered double hydroxide, and sol-gel coatings. Considering inevitable damages under complex service conditions, smart self-healing coatings are also introduced in each coating technology. …”
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4339
Challenges of Fuel Cell Technologies for the Needs of the Energy Transition to a Zero-carbon Technology
Published 2021-12-01“…The thorough structure optimization of the membrane-electrode complex and testing in actual operating conditions will accelerate the implementation of fuel cell technologies. …”
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4340
Ordered embeddings and intrinsic dimensionalities with information-ordered bottlenecks
Published 2025-01-01“…We present the information-ordered bottleneck (IOB), a neural layer designed to adaptively compress data into latent variables ordered by likelihood maximization. …”
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