Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early by Mariangela Morelli, Francesca Lessi, Serena Barachini, Serena Barachini, Romano Liotti, Romano Liotti, Nicola Montemurro, Paolo Perrini, Orazio Santo Santonocito, Carlo Gambacciani, Matija Snuderl, Francesco Pieri, Filippo Aquila, Azzurra Farnesi, Antonio Giuseppe Naccarato, Paolo Viacava, Francesco Cardarelli, Gianmarco Ferri, Gianmarco Ferri, Paul Mulholland, Diego Ottaviani, Fabiola Paiar, Gaetano Liberti, Francesco Pasqualetti, Francesco Pasqualetti, Michele Menicagli, Paolo Aretini, Giovanni Signore, Sara Franceschi, Chiara Maria Mazzanti

“…Surgical resection, temozolomide (TMZ) treatment, and radiotherapy remain the primary therapeutic options for GB, and no new therapies have been introduced in recent years. This therapeutic standstill is primarily due to preclinical approaches that do not fully respect the complexity of GB cell biology and fail to test efficiently anti-cancer treatments. …”
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Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. by Jonathan A Eisen, Robert S Coyne, Martin Wu, Dongying Wu, Mathangi Thiagarajan, Jennifer R Wortman, Jonathan H Badger, Qinghu Ren, Paolo Amedeo, Kristie M Jones, Luke J Tallon, Arthur L Delcher, Steven L Salzberg, Joana C Silva, Brian J Haas, William H Majoros, Maryam Farzad, Jane M Carlton, Roger K Smith, Jyoti Garg, Ronald E Pearlman, Kathleen M Karrer, Lei Sun, Gerard Manning, Nels C Elde, Aaron P Turkewitz, David J Asai, David E Wilkes, Yufeng Wang, Hong Cai, Kathleen Collins, B Andrew Stewart, Suzanne R Lee, Katarzyna Wilamowska, Zasha Weinberg, Walter L Ruzzo, Dorota Wloga, Jacek Gaertig, Joseph Frankel, Che-Chia Tsao, Martin A Gorovsky, Patrick J Keeling, Ross F Waller, Nicola J Patron, J Michael Cherry, Nicholas A Stover, Cynthia J Krieger, Christina del Toro, Hilary F Ryder, Sondra C Williamson, Rebecca A Barbeau, Eileen P Hamilton, Eduardo Orias

“…Overall, the gene set is robust, with more than 27,000 predicted protein-coding genes, 15,000 of which have strong matches to genes in other organisms. …”
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Effects of protein on green tea quality in a milk-tea model during heat treatment: Antioxidant activity, foaming properties, and unbound small-molecule metabolome by Nan Chen, Zeting Jiao, Ke Xie, Junying Liu, Peng Yao, Yangchao Luo, Tiehua Zhang, Ken Cheng, Changhui Zhao

“…The SDS-PAGE and Native-PAGE results further indicated that small-molecule compounds in tea formed covalent and noncovalent complexes by binding to milk proteins. …”
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Molecular Elucidation of Anthocyanin Accumulation Mechanisms in <i>Hippeastrum hybridum</i> Cultivars by Pengyu Guo, Chuanji Xing, Jiacheng Ye, Jing Xue, Luis A. J. Mur, Bao Di, Zongli Hu, Guoping Chen, Xiuhai Zhang, Xuqing Chen

“…Y2H assay isolated some transcription factors interacted with TTG1 (WD40 protein), including MYB3/39/44/306 and bHLH13/34/110, illustrating the possibility of forming MBW complexes. Our study provides a comprehensive characterization of anthocyanin composition. …”
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Approximate String Matching with Non-Overlapping Adjacent Unbalanced Translocations by Domenico Cantone, Simone Faro, Arianna Pavone

“…We also show that under the assumptions of equiprobability and independence of characters, our second algorithm has an <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi mathvariant="script">O</mi><mo>(</mo><mi>n</mi><msubsup><mo form="prefix">log</mo><mi>σ</mi><mn>2</mn></msubsup><mi>m</mi><mo>)</mo></mrow></semantics></math></inline-formula> average time complexity for an alphabet of size <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>σ</mi><mo>≥</mo><mn>4</mn></mrow></semantics></math></inline-formula>.…”
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The Structural Model of Happiness Based on Mindfulness with Mediator Role of Emotional Intelligence, Self-Compassion and Resilience by Mohammad Reza Tamannai far, Faezeh Taraffo

“…The Researchers used the Oxford Happiness Questionnaire-Short Form, the Freiburg Mindfulness Inventory-Short Form, the Bradberry and Greaves Emotional Intelligence Questionnaire, the Self-Compassion Scale-Short Form and the Connor-Davidson Resilience Scale-Short Form to collect the data. …”
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A novel Liesegang-patterned mineralized hydrogel drives bone regeneration with microstructure control by Yun Wang, Chao Fang, Li-Bo Mao, Yan-Hui-Zhi Feng, Yu-Feng Meng, Hai-Cheng Wang, Shu-Hong Yu, Zuo-Lin Wang

“…Bone regeneration remains a critical challenge in modern medicine. Recent advancements have focused on incorporating hierarchical microstructures into biomaterials to enhance osteogenesis. …”
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Stabilization of arsenic-contaminated soils with iron-lanthanide-loaded zeolite materials and its mechanisms by Yi Zhou, Chuanfang Fan, Peng Xiao, Yiting Wang, Xuhui Chang, Hong Li, Xuhan Huang, Ziqi Geng, Naiyi Yin, Xiaolin Cai, Yanshan Cui

“…This stabilization was attributed to the ligand exchange of hydroxyl groups (Fe–OH and La–OH loaded on zeolite after modification) with As, forming Fe/La–O–As complexes, which served as the central mechanism for soil As immobilization by the modified-zeolite composites. …”
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Synthesis and Reactivity of Oligo(ethylene glycol)-Tethered Morita–Baylis–Hillman Dimers in the Formation of Macrocyclic Structures Showing Remarkable Cytotoxicity by Marco Paolino, Mario Saletti, Jacopo Venditti, Arianna Zacchei, Alessandro Donati, Claudia Bonechi, Germano Giuliani, Stefania Lamponi, Andrea Cappelli

“…<b>Background/Objectives</b>: Crown ethers have received increasing interest owing to their ability to form stable complexes with cations. …”
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GAME THEORY AND FINANCIAL COMPONENTS FOR DETERMINING THE BUDGET PLACES OPTIMAL DISTRIBUTION IN THE HIGHER EDUCATION SYSTEM OF UKRAINE by Дмитро Бочаров, Наталія Стеблюк, Юлія Ульяновська, Наталія Волосова, Ольга Григораш, Ірина Петренко

“… The complexity and interdependence of management and decision-making problems in the system of higher education require new ideas and approaches, which necessitates the search for new management solutions using modern approaches and methods of economic and mathematical modeling. …”
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An Optical and mm-Wave Converged, Dual-Band, Multi-Beam Rotman Lens Antenna Array System Enabling Simplified Designs of B5G/mmW Base Stations for Ultra Dense Wireless Networks by Lauryn P. Smith, Charles A. Lynch, C. Alex Kaylor, L. Alberto Campos, Lin Cheng, Stephen E. Ralph, Manos M. Tentzeris

“…With the exponential demand for additional capacity, ultra-dense wireless networks (UDNs) have become an interesting area of study. One of the major challenges in UDN deployment is the complexity and cost of the base stations, which affect scalability. …”
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Deciphering the assembly process of PQQ dependent methanol dehydrogenase by Haichuan Zhou, Junqing Sun, Jian Cheng, Min Wu, Jie Bai, Qian Li, Jie Shen, Manman Han, Chen Yang, Liangpo Li, Yuwan Liu, Qichen Cao, Weidong Liu, Haixia Xiao, Hongjun Dong, Feng Gao, Huifeng Jiang

“…Using cryo-electron microscopy, we capture the structures of the intermediate complexes formed by the chaperone MxaJ and catalytic subunit MxaF during PQQ-dependent MDH maturation, revealing a chaperone-mediated molecular mechanism of cofactor incorporation. …”
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Advancements in Clinical Utilization of Recombinant Human Collagen: An Extensive Review by Isaac Wong Kai Jie, Kar Wai Alvin Lee, Song Eun Yoon, Jong Keun Song, Lisa Kwin Wah Chan, Cheuk Hung Lee, Eunji Jeong, Jin-Hyun Kim, Kyu-Ho Yi

“…However, challenges such as high production costs, regulatory complexities, and long-term biocompatibility remain barriers to widespread clinical adoption. …”
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Rare but Possible: Three Roots with Three Canals in Maxillary First Premolars in Pakistani Subpopulation by Shaher Bano, Malik Adeel Anwar, Khadija Arif, Rai Sadaf Nawaz, Annam Aziz, Fatima Khalil

“…Patients aged 13 years and older with premolars having fully erupted and completely formed roots were included. …”
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Health promotion and prevention of risks and diseases in Supplementary Health: a brief history by Kátia Audi Curci, Martha Regina de Oliveira, Michelle Mello de Souza Rangel, Simone Mendes

“…Strategies adopted intend to introduce health promotion and prevention of diseases into the context of a care plan integrated to other actions and complexities of services, promoting therefore health management qualification in order to improve the quality of life of private health care beneficiaries.…”
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Using AlphaFold-Multimer to study novel protein-protein interactions of predation essential hypothetical proteins in Bdellovibrio by Ibukun John Abulude, Isabel Cristina Rodríguez Luna, Alejandro Sánchez Varela, Andrew Camilli, Daniel E. Kadouri, Xianwu Guo

“…By applying Markov Cluster Algorithm and AlphaFold-Multimer to analyze the protein network and interaction partners of the AP-PEPs, we predicted high-confidence protein-protein interactions and two structurally similar but unique novel protein complexes formed among proteins of the Bd2209-Bd2212 and Bd2723-Bd2726 operons. …”
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Subacute sclerosing panencephalitis: clinical aspects and prognosis. The Brazilian Registry Panencefalite esclerosante subaguda, aspectos clínicos e prognóstico: Registro Brasileir... by MAGDA LAHORGUE NUNES, JADERSON COSTA DA COSTA, VANESSA M. STANCHER, ARON DIAMENT, FERNANDO ARITA, SÉRGIO ROSEMBERG, PAUL DYKEN

“…Although its frequency is declining because of measles eradication, we still have some cases being diagnosed. With the aim to describe epidemiological aspects of SSPE in Brazil, we sent a protocol to Child Neurologists around the country, 48 patients were registered, 27 (56 %) were from the southeast region, 34 (71%) were male and 35 (73%) white, 27 (56%) had measles, 9 (19%) had measles and were also immunized, 7 (14%) received only immunization, 1 patient had a probable neonatal form. …”
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Identification and direction of changes in work-life balance dimensions in Visegrad Group countries by Marta Domagalska Grędys, Adam Sagan, Katarzyna Piecuch

“…The differences identified at this level have led to the conclusion that the state of WLB of employees from the V4 countries is only partly determined by systemic-historical conditions. …”
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Principles and criteria affecting the physical identity shaping Iranian contemporary architecture (case study of the Second Pahlavi period) by Hamid Majedi, Seyede Sara Ebnoreza, Farh Habib

“…In most of the contemporary buildings of Tehran not all of them, a form imitation of Iranian traditional architecture or the contemporary western one has taken place. …”
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A review on the pathogenesis theory of cancerous toxin from the viewpoint of system theory by Tianhao Guo, Hongguang Zhou, Fangping Chen, Yutian Gu, Liu Li, Haibo Cheng

“…Ancient and modern TCM physicians have a similar understanding that the occurrence of cancer is related to toxin. …”
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