SOLVENCY II – THE NEW EU SOLVENCY REGIME ON THE INSURANCE MARKET by Emilia CLIPICI

“…The main causes that lead to insurer’s solvency issues such as the underwriting, investment or reinsurance deficiencies have remained the same over time. However, their incidence is increasing, as well as their complexity. …”
Get full text

A Head-Mounted Spectacle Frame for the Study of Mouse Lens-Induced Myopia by Yangshun Gu, Baisheng Xu, Chunfei Feng, Yang Ni, Qin Wu, Chixin Du, Nan Hong, Peng Li, Zhihua Ding, Bo Jiang

“…These techniques each have its advantages, disadvantages when considering the devices stability, safety, complexity, effectiveness, and so forth. …”
Get full text

Neuroeducational Environment for Acquisition of Competencies in the Field of End-To-End Digital Technologies (Neurotechnology) in the Conditions of Digital Transformation by M. E. Mazurov, A. A. Mikryukov, V. A. Titov, I. G. Fedorov

“…The architecture and components of the technological platform of the neuroeducational environment based on neuroeducational complexes have been developed. A general methodological approach has been developed for teaching the basics of neurotechnology based on standard and selective neural networks and the peculiarities of their application in the framework of the digital economy program. …”
Get full text

Dynamic Mechanical and Charlesby-Pinner Analyses of Radiation Cross-Linked Ethylene-Vinyl Acetate Copolymer (EVA) by Anna Svarcova, Petr Svoboda

“….% VA) and EVA 212 (12 wt.% VA) having the same melt flow indices of 2 g/10 min. The impact of electron irradiation at levels of 60, 120, and 180 kGy was studied. …”
Get full text

HISTOCHEMICAL INVESTIGATION OF GLYCOSAMINOGLYCANS OF THE MANDIBULAR ALVEOLAR PROCESS IN PHARMACOLOGICAL CORRECTION OF EXPERIMENTAL OSTEOPOROSIS AND PERIODONTITIS by O.I. Hodovana

“…In 2 months’ treatment with this medication, numerous foci of resorption in the form of oval newly formed lacunae were seen in compact bone of the alveolar process in the mandible. …”
Get full text

Improving the conditions of regional hemodinamics of the eyes as a method of treatment in optic neuropathy at short-sightedness of high degree. by N. G. Zavgorodnyaya, O. O. Denisova, N. A. Vesnina, N. A. Kudinova- Savchenko

“…Study group comprised 28 patients (32 eyes). Complex of medications included vasodilators, nootropics and neuroprotective agents , vitamins. …”
Get full text

Large-scale phylogenomic insights into the evolution of the Hymenochaetales by Heng Zhao, Fang Wu, Sundy Maurice, Igor N. Pavlov, Konstantin V. Krutovsky, Hong-Gao Liu, Yuan Yuan, Yu-Cheng Dai

“…The Hymenochaetales is an order with most species as wood-inhabiting fungi that have high phylogenetic complexity and morphological diversity. …”
Get full text

Організація виставкових комплексів на базі ботанічних садів by Kseniia Rozhak-Lytvynenko, Vita Нorupakha

“…Currently, exhibition activity is considered as a form of advertising communications. Analyzing the development of exhibition spaces and complexes, it can be noted that the authors’ creative ideas have always been based on the search for original architectural, planning and artistic solutions, which reflected, inter alia, the development of science and technology. …”
Get full text

Sensitive and Selective Spectrophotometric Determination of Gabapentin in Capsules Using Two Nitrophenols as Chromogenic Agents by Sameer A. M. Abdulrahman, Kanakapura Basavaiah

“…Two simple and selective spectrophotometric methods have been proposed for the determination of gabapentin (GBP) in pure form and in capsules. …”
Get full text

A systematic review of computational simulation methods for predicting the toxicity of chemical compounds by Akram Tabrizi, Fatemeh Paridokht, Yaser Khorshidi Behzadi, Rezvan Zendehdel

“…Introduction: With the rapid development of new chemicals across various industries and the growing need for efficient and accurate toxicity assessments, in silico methods have emerged as a screening tool due to their cost-effectiveness, time efficiency, and reduction in animal testing. …”
Get full text

Identification of Potential Inhibitors of Histone Deacetylase 6 Through Virtual Screening and Molecular Dynamics Simulation Approach: Implications in Neurodegenerative Diseases by Anas Shamsi, Moyad Shahwan, Azna Zuberi, Nojood Altwaijry

“…The MD simulation results showed that stable protein–ligand complexes of penfluridol and pimozide with HDAC6 were formed. …”
Get full text

Community guidelines to increase the reusability of marine microfossil assemblage data by L. Jonkers, T. Strack, M. Alonso-Garcia, S. D'haenens, S. D'haenens, R. Huber, M. Kucera, I. Hernández-Almeida, C. L. C. Jones, B. Metcalfe, B. Metcalfe, R. Saraswat, L. Silye, S. K. Verma, M. N. Abd Malek, G. Auer, C. F. Barbosa, M. A. Barcena, K.-H. Baumann, K.-H. Baumann, F. Boscolo-Galazzo, J. A. S. Calvelo, L. Capotondi, M. Caratelli, M. Caratelli, J. Cardich, H. Carvajal-Chitty, M. Chroustová, H. K. Coxall, R. M. de Mello, A. de Vernal, P. Diz, K. M. Edgar, H. L. Filipsson, Á. Fraguas, H. L. Furlong, G. Galli, G. Galli, N. L. García Chapori, R. Granger, J. Groeneveld, A. Imam, R. Jackson, D. Lazarus, J. Meilland, M. Molčan Matejová, R. Morard, C. Morigi, S. N. Nielsen, D. Ochoa, M. R. Petrizzo, A. S. Rigual-Hernández, M. C. Rillo, M. L. Staitis, G. Tanık, R. Tapia, N. Vats, B. S. Wade, A. E. Weinmann

“…Determining the optimal forms and formats for data sharing are obvious next steps the community needs to take.…”
Get full text

Domain swapping: a mathematical model for quantitative assessment of structural effects by Irena Roterman, Katarzyna Stapor, Dawid Dułak, Leszek Konieczny

“…Domains with a hydrophobicity system that is incompatible with the micelle‐like structure have also been identified. This incompatibility is the form of structural codes related to biological function.…”
Get full text

In Silico Evaluation of Potential NDM-1 Inhibitors: An Integrated Docking and Molecular Dynamics Approach by Eduvan Valencia, Mauricio Galvis, Jorge Nisperuza, Vladimir Ballesteros, Fredy Mesa

“…Molecular docking was run with AutoDock4 and AutoDock4Zn, determining that molecules M26 (−13.23 kcal/mol with AutoDock4 and −13.11 kcal/mol with AutoDockZn) and M25 (−10.61 kcal/mol with AutoDock4 and −11.18 kcal/mol with AutoDockZn) presented the best binding energy affinities with NDM-1. The M26 molecule formed six hydrogen bonds with the enzyme. <b>Results:</b> MD simulations, performed with GROMACS, indicated that the NDM-1-M26, NDM-1-M35, and NDM-1-M37 complexes showed conformational stability and flexibility. …”
Get full text

Analysis of retirees' knowledge return in the supply chain of Isfahan Refinery with a combined approach of interpretive structural modeling and structural equation modeling by Mehran Ziaeian, Somayeh Ahmadzadeh, Abdolrasoul Yazdi

“…Among these limitations, we can mention the lack of examination of different cycles between stimuli, which has always existed as a structural limitation in the structural equation technique, and it is suggested that in future research, the return paths between the relationships formed in this study be examined. Also, considering the use of a questionnaire as a data collection tool and its distribution among Isfahan Refinery employees and managers and academic experts, their mindset and attitude in completing the questionnaire may have affected the results of the present study. …”
Get full text

A Considerable Contribution to Development of Fundamentals of Scientific Knowledge in the Field of International Economic Law (review of the book «International Economic Law and Re... by L. P. Anufrieva

“…The author of the afore-referred edition, being Doctor of Laws, Professor, occupies the post of the Head of the Chair of International Law of the Diplomatic Academy, Ministry of Foreign Affairs of Russian Federation.Notwithstanding the point that through the last years within Russia a substantial quantities of special publications related to the International Economic Law have been emerging on rather regular basis, the effective, fundamental and system analysis of the International Economic Law issues realized from the stand of the Law theory (including International Law theory) leaves a lot to be desired.Unfortunate fact, but actually Russian legal science in the most of cases is represented by textbooks and casebooks which is proper as well for the field of the International Economic Law Just the same gender is immune to the edition commissioned by prof A A Kovalev.In the Introductory Note to the textbook it is stressed out that the item was in its essence deemed for use to require the educational objectives, however it is not to be construed as an obstacle for using by the practitioners, i e those who being the members of state authorities staff, have the powers to formulate and affect the public interests pursuing in the field of international economic relations: both scholars or public executives, specialists in the theory of law, etc.The book reflects the growing complexity of the international economic relationships from the one hand, and appearance due to this of certain legal problems in the International and Municipal law systems – from the other side Having differentiated the two notions, namely: «international economic law» and «international economic activities», – the author does seek by the same very important target – to demonstrate prima facie, that the international economic activities are consisted not only of the acts and deeds of public entities (those international and municipal having the interstate nature), but also private subjects of law (natural and moral persons including transnational entities or multinational companies, their consortia, etc ); it is to be shown, secondly, that the International Economic Law is capable to regulate only certain quantity of the international economic relationships, entered into the general notion of foreign economic activities, and thirdly, that between the regulation of foreign economic activities formed by the relationship where the private subjects of law are involved, and the same which consists of public relationship (mostly between the state-powers), there is no «Chinese Wall».…”
Get full text

Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice. by Tim Hendrikx, Veerle Bieghs, Sofie M A Walenbergh, Patrick J van Gorp, Fons Verheyen, Mike L J Jeurissen, Mandy M F Steinbusch, Nathalie Vaes, Christoph J Binder, Ger H Koek, Rinke Stienstra, Mihai G Netea, Marten H Hofker, Ronit Shiri-Sverdlov

“…Previously, cholesterol crystals have been shown to induce the activation of inflammasomes. …”
Get full text

A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation. by Eoin N Leen, Frédéric Sorgeloos, Samantha Correia, Yasmin Chaudhry, Fabien Cannac, Chiara Pastore, Yingqi Xu, Stephen C Graham, Stephen J Matthews, Ian G Goodfellow, Stephen Curry

“…NMR spectroscopy was used to define the VPg binding site on eIF4G HEAT-1, which was confirmed by mutagenesis and binding assays. We have found that this site is non-overlapping with the binding site for eIF4A on eIF4G HEAT-1 by demonstrating that norovirus VPg can form ternary VPg-eIF4G-eIF4A complexes. …”
Get full text

ANALYSIS OF SURFACE DEFECTS OF ALUMINUM AND ITS ALLOYS WITH A SCANNING KELVIN PROBE by A. K. Tyavlovsky, A. L. Zharin, O. K. Gusev, R. I. Varabei, N. I. Muhurov, G. V. Sharonov, K. U. Pantsialeyeu

“…The results of scanning were plotted in a form of contact potential difference (CPD) distribution map. …”
Get full text

Fast Anomaly Detection for Vision-Based Industrial Inspection Using Cascades of Null Subspace PCA Detectors by Muhammad Bilal, Muhammad Shehzad Hanif

“…While recently several methods have been reported in the literature that have demonstrated impressive detection performance on standard benchmarks, they necessarily rely on computationally intensive CNN architectures and post-processing techniques, necessitating access to high-end GPU hardware and limiting practical deployment in resource-constrained settings. …”
Get full text