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4101
S100a4 promotes metastatic transformation in non-metastatic liver cancer cells through NMIIa binding: mechanistic insights
Published 2025-07-01“…Mechanistically, S100A4 overexpression significantly downregulated E-cadherin expression while upregulating Twist1, N-cadherin, and Vimentin levels. Notably, S100A4 formed a complex with NMIIA in HCC cells, and NMIIA silencing suppressed S100A4-induced changes in EMT-related protein expression. …”
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4102
CHANGES IN THE DENTAL STATUS OF PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
Published 2022-03-01“…Diagnosis and treatment of dental diseases in patients with NAFLD will allow the dentist to break the "vicious circle" of comorbidity and will help in the complex therapy of such patients. …”
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4103
Features of psychosocial functioning of patients with combat traumatic brain injury of varying severity: analysis of interconnection
Published 2024-12-01“…The study of socio-psychological adaptation is important for understanding the complex picture of changes in the psychosocial functioning of patients with TBI. …”
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4104
Concept COMMUNITY in Autobiography by Barack Obama “Dreams from my Father”
Published 2017-07-01“…The concept of COMMUNITY by Barack Obama has a complicated structure and includes a number of other complex concepts, having axiological load and important to the majority of American citizens, such as IDENTITY, RESPONSIBILITY, COMMITMENT, UNITY and some others.…”
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4105
MOLECULAR WEIGHT DETERMINATION AND METAL ION REQUIREMENT OF PHOSPHATIDATE PHOSPHOHYDROLASE PURIFIED FROM CYTOSOLIC FRACTION OF RAT LIVER
Published 2002-09-01“…Magnesium ion is probably the only divalent cation capable of generating proper enzyme-metal-substrate complex necessary for the catalytic activity.…”
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4106
TOOLS FOR ENSURING ECONOMIC SECURITY OF RURAL AREAS DEVELOPMENT
Published 2019-01-01“…The studied Chernozem, located in the southeast of the Romanian Plain, more precisely in the Baragan Field, is directly investigated with the environmental factors, which together form homogeneous ecological territory units (UT), these UT having specific advantages at various agricultural uses, such as wheat, corn, sunflower, peas and soybean crops. …”
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4107
A Paired Database of Predicted and Experimental Protein Peptide Binding Information
Published 2025-08-01“…Complexes were selected for inclusion in PEPBI using eight stringent structural criteria, including peptide length (5–20 residues), structure resolution (≤2.0 Å), less than 30% sequence identity between complexes, and having a corresponding unbound protein structure in the Protein Data Bank with at least 90% sequence identity to the bound form with minimal changes in the binding pocket. …”
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4108
Educational effectiveness of cognitive and metacognitive strategies on educational self-destructive behaviors and negative self-evaluation thinking in Arabic lessons
Published 2024-09-01“…It is said that the most important learning strategies can be mentioned are cognitive and metacognitive strategies. Researchers have classified students' learning activities in the form of three cognitive, emotional, and metacognitive activities. …”
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4109
Architecture and the Time of Space
Published 2020-06-01“…While there is much architecture theory advanced from this perspective lining my own bookshelves and utilized in my work as an educator. The concerns that have always called me towards thinking about architecture as the imagined and constructed world in which we live are those that query the very nature of concepts, notions, ideologies and intellectual constructions and beliefs upon which culture and society – architecture as both a cultural product and a social actor – are formed. …”
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4110
The Validity of Cryptocurrency Transactions and the Analysis of Associated Disputes
Published 2025-03-01“…Cryptocurrency transactions, in whatever form they may occur, have the potential to lead to legal conflicts under various legal categories. …”
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4111
THE ESSENCE OF AN IMAGE IN ENGLISH-AMERICAN IMAGISM: SINGULAR VERSUS UNIVERSAL
Published 2023-05-01“…The fight doesn’t have to be limited only to opposing Romanticism (as in Hulme’s “Romanticism and Classicism”). …”
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4112
A COMPREHENSIVE APPROACH TO THE TREATMENT OF PATIENTS WITH ALVEOLAR RIDGE ATROPHY IN PARODONTAL DISEASES: FROM THE USE OF BONE AUGMENTATION TO THE RESTORATION OF FUNCTIONAL OCCLUS...
Published 2021-06-01“… The rate of atrophy is significantly lower with the included dentition defects than with the final ones, as the teeth that limit the newly formed defect are natural constraints for bone resorption. …”
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4113
Retrospective Analysis of Experimental and Clinical Studies of Flakozid in Viral Hepatitis
Published 2021-11-01“…"Flakozid" is recommended in clinical practice in the complex treatment of hepatitis A and B. In vitro experiments have established a high antiviral activity of flakozid against the hepatitis C virus, which justifies the possibility of conducting clinical studies of the drug in patients with the viral hepatitis C.…”
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4114
THE TERM COMBINATION AND THE METAPHOR IN THE OFFICIAL BUSINESS DOCUMENT: COGNITIVE ASPECT
Published 2023-05-01“…We tried to justify the hypothesis according to which these subjects have common features in the lexical form and the military lexical meaning. …”
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4115
Dépôts et pratiques symboliques dans l’établissement aristocratique gaulois de Varennes-sur-Seine, la Justice (Seine-et-Marne)
Published 2021-12-01“…This assortment of objects may have been a talisman or a kit considered to have magical virtues, and it may have been thrown away or lost in a domestic dump. …”
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4116
The role of ubiquitination and deubiquitination in urological tumours
Published 2025-07-01“…The roles of these processes in urinary diseases are complex, encompassing various aspects of signaling, protein stability, and cellular metabolism. …”
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4117
A high‐resolution genomic analysis of multidrug‐resistant hospital outbreaks of Klebsiella pneumoniae
Published 2015-02-01“…We suggest that the early detection of a specific NDM‐1 containing lineage in 2011 would have alerted the high‐dependency ward staff to intervene. …”
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4118
High‐Throughput Formation of Pre‐Vascularized hiPSC‐Derived Hepatobiliary Organoids on a Chip via Nonparenchymal Cell Grafting
Published 2025-02-01“…It is believed that nonparenchymal cell grafting will offer a novel technical route to form a high‐fidelity complex in vitro model for tissue engineering and regenerative medicine.…”
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4119
PETRO- AND PALEOMAGNETIC STUDIES OF BASALTS OF THE UPPER DEVONIAN APPAINSKAYA SUITE (WESTERN YAKUTIA)
Published 2016-12-01“…It is possible that after the formation of the Appainskaya suite (Fran), the Siberian platform could pass the three hot spots representing the modern Atlantic islands near the northwestern coast of Africa (Canary, Madeira and Azores, i.e. the northern flank of the African superplume). These hotspots might have formed the tracks (Fig. 15) that controlled the intrusion of alkaline ultrabasic melts and formation of kimberlites in the Late Devon – Early Carbon.Conclusion. …”
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4120
Application of Laplace Transform For Solving Population Growth and Decay Models.
Published 2024“…Laplace can be used to convert complex differential equations to a simpler form having polynomials, convert derivatives into multiple domain variables, and then convert the polynomials back to the differential equation using the Inverse Laplace transform, telecommunication field to send signals to both sides of the medium. …”
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