Health status deterioration in field-protective forest belts in northeastern Bulgaria by Margarita Georgieva, Georgi Georgiev, Plamen Mirchev, Veselin Ivanov, Mihaela Hristova, Sevdalin Belilov, Yonko Dodev, Svetozar Madzhov, Lyubomira Georgieva

“…Dam-age on shoots and stems of ash trees was caused by the insect pests Cicada orni, Cossus cossus, Zeuzera pyrina, Hylesinus fraxini, H. crenatus, and on leaves – by leaf-damaging and gall-forming fly Dasineura acrophila and D. fraxini. The complex of fungal species Armillaria mellea, Coriolopsis gallica, Cytospora pulchelia, Daldinia concentrica, Diplodia sp., Helicobasidium purpureum, Hysterographium fraxini, were identified on ash trees. …”
Get full text

Bacillus velezensis B63 and chitosan control root rot, improve growth and alter the rhizosphere microbiome of geranium by Tarek R. ELSAYED, Nadia A.M. EL-SAID, Fatmah A. SAFHI, Nour El Houda A. REYAD

“…The root rot complex of geranium plants caused by Rhizoctonia solani and Macrophomina phaseolina is a major threat, and control of these pathogens predominantly relies on chemicals. …”
Get full text

Relaxation-weighted MRI analysis of biofilm EPS: Differentiating biopolymers, cells, and water by Matthew R. Willett, Sarah L. Codd, Joseph D. Seymour, Catherine M. Kirkland

“…Biofilms are a highly complex community of microorganisms embedded in a protective extracellular polymeric substance (EPS). …”
Get full text

Using topological data analysis and machine learning to predict customer churn by Marcel Sagming, Reolyn Heymann, Maria Vivien Visaya

“…The availability of stored customer data in the form of big data, together with the use of advanced and tuned machine learning (ML) algorithms, have paved the way for the realisation and extraction of useful features associated with customer behaviour and consequently the prediction of customer churn. …”
Get full text

Prmt1-mediated methylation regulates Ncoa4 stability to transactivate Adamts genes and promote bone extracellular matrix degradation in chronic hematogenous osteomyelitis by Xun Chen, Ning Duan, Wentao Zhang, Tao Song, Fei Cong

“…Our findings revealed that the inflammatory microenvironment specifically upregulated Prmt1 expression in osteoblasts and osteocytes, which facilitated its interaction with the transcriptional activator Ncoa4 (nuclear receptor coactivator 4) and mediated Ncoa4 arginine methylation, thereby enhancing Ncoa4 protein stability. Methylated Ncoa4 formed a transcriptional complex with the histone acetyltransferase Cbp (CREB-binding protein) and transcription factor Ap1 (Activator protein 1), driving the expression of four Adamts genes (Adamts3/8/12/14) that promoted extracellular matrix (ECM) degradation in osteoblasts and osteocytes. …”
Get full text

Analysis of the Raman spectrum of high-power amplifiers of wireless communication systems by Minh Tuong Nguyen, Viktor I. Nefedov, Igor V. Kozlovsky, Alexey V. Malafeev, Kirill A. Selenya, Natalia A. Mirolyubova

“…In the radio transmitting and receiving paths of communication systems with multiple access, multiple signals are used (the sum of the power of the subscriber signals) with very complex types of digital envelope modulation, so they use wide working bands. …”
Get full text

What ethical challenges arise in global health programmes? A qualitative case study of global health programme leaders’ experiences by James V Lavery, Michelle Grek, Ashley Graham, David Addiss

“…The challenges often result in divided or conflicting loyalties for GHP leaders and uncertainty about what to do. We have characterised this form of uncertainty as ‘moral ambiguity,’ which we define as the inability to discern the best ethical way forward when there is tension or conflict among multiple stakeholder interests.Conclusions Our findings suggest that moral ambiguity is a common experience for GHP leaders and that current approaches to global health ethics fail to guide and support GHP leaders to recognise and address moral ambiguity and limit the distress it can cause. …”
Get full text

Prediction of technological properties of wheat flour by combination of UV-VIS-NIR spectroscopy and multivariate analysis methods by R. A. Platova, E. V. Zhirkova, D. A. Metlenkin, A. A. Lysenkova, Yu. T. Platov, V. A. Rassulov

“…Over the last decades, optical spectroscopy methods that do not require complex sample preparation have been widely used to identify and control the composition of food products. …”
Get full text

Diseases with major salivary glands enlargement and orbits, nose and paranasal sinuses lesions in the practice of a rheumatologist by E. V. Sokol, A. V. Torgashina, B. D. Chaltsev, Yu. I. Khvan, O. A. Golovina

“…Orbital lesions were observed in 18 patients: in 7 with IgG4-RD, in 5 with idiopathic inflammatory pseudotumor, in 2 with sarcoidosis, in 2 with GPA, and in 1 each with non Langerhans cell histiocytosis and dirofilariasis. Nasal lesions in the form of chronic rhinosinusitis with or without nasal septum perforation, were found in 18 patients, 12 of whom suffered GPA and 6 – IgG4-RD.Two algorithms, that can facilitate the choice of additional studies and the direction of diagnostic search have been proposed for practicing rheumatologists.Conclusion. …”
Get full text

Freedom of movement for persons in the European Union Law by Novičić Žaklina

“…In this article the author analyses the evolution of complex corpus of legislation concerning the freedom of movement for persons in European Union Law. …”
Get full text

Primary posterior capsulorexis: historical aspects and the current state of the issue by E.V. Egorova, A.O. Direev

“…However, some studies have shown the possibility of partial or complete «closure» of the capsulorexis area by proliferating epithelial cells of the lens (ECL) in adult patients. …”
Get full text

DEICTIC MITIGATION VS COMMISSIVE ACTS IN POLITICAL INTERVIEW (BASED ON THE MODERN EUROPEAN DISCOURSE OF AID TO UKRAINE) by Nataliia K. Kravchenko, Sviatoslav I. Vylinskyi, Oleksandr I. Yudenko

“…The prospect for further research is the analysis of all types of mitigators, including bushes, hedges and shields, in their projection on rhetorical and manipulative methods of argumentation in political discourse as manifested by the discourse-forming concept “Caution”.…”
Get full text

The cliché factor in the description of word-containing semiosis: language standard and language boundaries by Andrey Vdovichenko

“…In order to achieve changes in external cognitive states (which have not yet occurred at the time of the action, but are only planned), the semiotic actor makes attempts to influence, manifesting actional modes of his consciousness under given conditions in complex ways. …”
Get full text

Dimensionality cutback and deep learning algorithms efficacy as to the breast cancer diagnostic dataset by Gennady Chuiko, Denys Honcharov

“…Breast cancer is a significant threat because it is the most frequently diagnosed form of cancer and one of the leading causes of mortality among women. …”
Get full text

PATHOPHISIOLOGY OF SICKLE CELL DISEASE AND NEW DRUGS FOR THE TREATMENT by Lucia De Franceschi

“…Dense, dehydrated erythrocytes are likely to undergo instant polymerization in conditions of mild hypoxia due to their high HbS concentration, and  HbS polymers may be formed under normal oxygen pressure. Pathophysiological studies have shown that the dense, dehydrated red cells may play a central role in acute and chronic clinical manifestations of sickle cell disease, in which intravascular sickling in capillaries and small vessels leads to vaso-occlusion and impaired blood flow in a variety of organs and tissue. …”
Get full text

Capsanthin inhibits migration and reduces N-linked glycosylation of PD-L1 via the EZH2-PD-L1 axis in triple-negative breast cancer brain metastasis by Yi-Chung Chien, Jia-Yan Wu, Liang-Chih Liu, Yung-Luen Yu

“…While PD-L1 inhibitors have shown success in various cancer types, their effectiveness in TNBC brain metastases remains to be fully investigated. …”
Get full text

The organization of serotonergic fibers in the Pacific angelshark brain: neuroanatomical and supercomputing analyses by Skirmantas Janušonis, Ralf Metzler, Thomas Vojta

“…Serotonergic axons (fibers) are a universal feature of all vertebrate brains. They form meshworks, typically quantified with regional density measurements, and appear to support neuroplasticity. …”
Get full text

A Fast-Response Method for Determining the Amplitude of a Signal in Microprocessor Automation and Control Systems with Frequency Fluctuations by Yu. V. Rumiantsev, F. A. Romaniuk, V. Yu. Rumiantsev

“…In this case, both sinusoidal input signals and complex ones, close to the real secondary signals of measuring transformers, were used as test actions. …”
Get full text

Meta-analysis of TCF7L2 and SLC30A8 gene polymorphisms concerning type 2 diabetes risk by Jethendra Kumar Muruganantham, Ramakrishnan Veerabathiran

“…T2DM is the most prevalent form, accounting for 90% of cases. Genetic variations in genes like SLC30 A8 (rs13266634) and TCF7L2 (rs7903146 and rs12255372) have been linked to T2DM, although their precise role is not fully understood. …”
Get full text

68Ga-labeled fluorinated benzamide derivatives for positron emission tomography imaging of melanoma. by Chaewon Lee, Boreum Song, Eunsu Kim, Yejin Seo, Dagyeong Hong, Jiyu Kim, Wookyeong Jeong, Seong-Young Kwon, Dong-Yeon Kim, Ayoung Pyo

“…Malignant melanoma tends to aggressively metastasize, resulting in it being a potentially lethal form of skin cancer with high mortality rates. The advanced stages of melanoma have a very poor prognosis because of the high tendency for metastasis, and there is therefore, a strong desire to develop efficient technology for the early detection of melanoma. …”
Get full text