Metal-Induced Genotoxic Events: Possible Distinction Between Sporadic and Familial ALS by William Wu Kim, Gregory Zarus, Breanna Alman, Patricia Ruiz, Moon Han, Paul Mehta, Chao Ji, Hoormat Qureshi, James Antonini, Mohammad Shoeb

“…Substantial evidence associates heavy metal exposure to genotoxic endpoints in both forms of ALS; however, a data gap has been observed for several of these endpoints. …”
Get full text

The Strategy of Young Citizens in the Field of Unanswered Demands: A Qualitative Study in Yazd City by Fezzeh Abolhasani, Mahnaz Farahmand, Hossein Afrasiabi, Seyed Reza Javadian

“…In some cases, citizens' remedial actions attempted to address gaps and alleviate deprivations, thereby serving the broader interests of the society. …”
Get full text

Unlocking the potential of microalgae-derived therapeutic carriers: Characteristics, types, and nanomedical applications by Peiyi Wang, Changhong Liu, Lei Zheng

“…Traditional drug delivery systems are constrained by limitations such as low drug-loading efficiency, immunogenicity, and functional simplicity, rendering them inadequate to address the demands of complex pathological scenarios. Microalgae have emerged as a promising alternative system, possessing not only health benefits derived from their bioactive compounds but also inherent properties that naturally align with delivery system requirements. …”
Get full text

Repurposing FDA-Approved Agents to Develop a Prototype <i>Helicobacter pylori</i> Shikimate Kinase (HPSK) Inhibitor: A Computational Approach Using Virtual Screening, MM-GBSA Calcu... by Abdulaziz H. Al Khzem, Tagyedeen H. Shoaib, Rua M. Mukhtar, Mansour S. Alturki, Mohamed S. Gomaa, Dania Hussein, Nada Tawfeeq, Mohsina Bano, Mohammad Sarafroz, Raghad Alzahrani, Hanin Alghamdi, Thankhoe A. Rants’o

“…While current therapies face challenges from rising antibiotic resistance, particularly to clarithromycin, alongside treatment complexity and costs, the World Health Organization has prioritized the development of new antibiotics to combat this high-risk pathogen. …”
Get full text

Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya by Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo

“…Randomized studies of 5FU and other topical therapies in LMICs are needed to evaluate their use in closing the current precancer treatment gaps in these settings.…”
Get full text

Rapid identification of sepsis in the emergency department by Chadd K. Kraus, H. Bryant Nguyen, Ryan C. Jacobsen, Nathan A. Ledeboer, Larissa S. May, Hollis R. O'Neal Jr., Michael A. Puskarich, Todd W. Rice, Wesley H. Self, Richard E. Rothman

“…Abstract Objectives Recent research has helped define the complex pathways in sepsis, affording new opportunities for advancing diagnostics tests. …”
Get full text

Validity and Reliability of the Multidimensional Scale of Perceived Social Support (MSPSS) in Greek Secondary School Students by Vasiliki Efthymiou, George P. Chrousos, Kalliopi Kounenou, Antonios Kalamatianos, Christos Pezirkianidis, Markos Korelopoulos, Charikleia Stefanaki, Ntina Kourmousi

“…<b>Background/Objectives</b>: Resilience—a complex phenomenon embracing a number of factors on various levels—seems to be a most important skill to survive this vulnerable phase. …”
Get full text

Patterns of Zoological Diversity in Iran—A Review by Sajad Noori, Reza Zahiri, Gholam Hosein Yusefi, Mahdi Rajabizadeh, Oliver Hawlitschek, Ehsan Rakhshani, Martin Husemann, Hossein Rajaei

“…Iran is a country characterized by high biodiversity and complex biogeographic patterns. Its diverse landscape and steep climatic gradients have resulted in significant faunal diversity and high level of endemism. …”
Get full text

A Review of Microreactors for Process Intensification by Crizha Ann Bugay, Mae Czarella Caballas, Steven Brian Mercado, Jason Franco Rubio, Patricia Kayla Serote, Patrick Norman Villarte, Rugi Vicente C. Rubi

“…Fabrication techniques, including microfabrication, are essential for creating complex designs and ensuring reliability. This review addresses challenges and research gaps while showcasing the versatility of microreactors. …”
Get full text

Predictive analytics in education- enhancing student achievement through machine learning by Sunawar khan, Tehseen Mazhar, Tariq Shahzad, Muhammad Amir khan, Wajahat Waheed, Ahsen Waheed, Habib Hamam

“…This architecture effectively captures complex feature interactions and provides actionable insights for educators. …”
Get full text

Can generative AI Be an effective Co-Teacher? An experiment by Ahnaf Chowdhury Niloy, Salma Akter, Jakia Sultana, Md Azizur Rahman, Nayeema Sultana, Tasnem Islam Prome, Nusrat Jahan Isha, Muslima Afroz, Mashruha Zabeen, Mehnaz Tabassum, Rup Chowdhury, Moumita Sarkar, Saadman Mahmud, Amit Sen

“…Future studies hold potential to explore more complex relationships and allow a geographically stratified sample for deeper insights. …”
Get full text

Multilevel Feature Cross-Fusion-Based High-Resolution Remote Sensing Wetland Landscape Classification and Landscape Pattern Evolution Analysis by Sijia Sun, Biao Wang, Zhenghao Jiang, Ziyan Li, Sheng Xu, Chengrong Pan, Jun Qin, Yanlan Wu, Peng Zhang

“…To alleviate the semantic confusion caused by different-level features with semantic gaps during fusion, we introduce a deep–shallow feature cross-fusion (DSFCF) module between the encoder and the decoder. …”
Get full text

Experiences and needs of older patients with stroke in China involved in rehabilitation decision-making: a qualitative study by Zining Guo, Sining Zeng, Keyu Ling, Shufan Chen, Ting Yao, Haihan Li, Ling Xu, Xiaoping Zhu

“…Abstract Background Shared decision-making is recommended for stroke rehabilitation. However, the complexity of the rehabilitation modalities exposes patients to decision-making conflicts, exacerbates their disabilities, and diminishes their quality of life. …”
Get full text

A Review on Deep Learning for Quality of Life Assessment Through the Use of Wearable Data by Vasileios Skaramagkas, Ioannis Kyprakis, Georgia S. Karanasiou, Dimitris I. Fotiadis, Manolis Tsiknakis

“…DL models can analyze vast and complex datasets, including patient-reported outcomes, medical images, and physiological signals, enabling a deeper understanding of factors influencing an individual&#x0027;s QoL. …”
Get full text

Optimal Power Flow: A Review of State-of-the-Art Techniques and Future Perspectives by Ahmed Babiker, Sulaiman S. Ahmad, Ijaz Ahmed, Muhammad Khalid, Mohammad A. Abido, Fahad Saleh Al-Ismail

“…Ultimately, the paper highlights key gaps, challenges, and opportunities for future research.…”
Get full text

Advancing Knowledge on Machine Learning Algorithms for Predicting Childhood Vaccination Defaulters in Ghana: A Comparative Performance Analysis by Eliezer Ofori Odei-Lartey, Stephaney Gyaase, Dominic Asamoah, Thomas Gyan, Kwaku Poku Asante, Michael Asante

“…Integrating such models into routine immunization programs could enable data-driven targeting of high-risk groups, supporting policymakers in strategies to close vaccination coverage gaps.…”
Get full text

Genetics of Wool and Cashmere Fibre: Progress, Challenges, and Future Research by Huitong Zhou, Lingrong Bai, Shaobin Li, Wenhao Li, Jiqing Wang, Jinzhong Tao, Jon G. H. Hickford

“…This is not straight-forward, given the large number of similar yet unique genes that produce the proteins and the gaps that remain in their identification and characterisation. …”
Get full text

Interventions to Support Transitions in Care Among Patients With Cancer: A Scoping Review by Negar Rezaei, Jaling Kersen, Abigail Thomas, Stefan Kurbatfinski, Diane Lorenzetti, Khara Marissa Sauro

“…ABSTRACT Background The cancer journey from diagnosis through survivorship is complex and involves care from many healthcare providers across a variety of settings. …”
Get full text

Epidemiological landscape and genetic prospects for marker-assisted selection in Kazakh sheep by Shynggys Orkara, Aigerim Khamzina, Nurlan Sandybayev, Rano Sattarova, Ainur Davletova, Kadyrzhan Khamzin, Kisun Pokharel, Primkul Ibragimov, Nadezhda Burambayeva, Darkhan Smagulov

“…Recent molecular studies have identified promising genetic markers associated with disease resistance, notably polymorphisms in the MHC complex (particularly DRB1 and DQB1 loci) conferring protection against parasitic infections and the PRNP gene variants influencing scrapie susceptibility. …”
Get full text

Synergising agricultural systems: A critical review of the interdependencies within the water-energy-food nexus for sustainable futures by Krishna Mondal, Manojit Chowdhury, Suman Dutta, Ajay N. Satpute, Ayushi Jha, Suyog Khose, Vishal Gupta, Sumanta Das

Get full text