Association analysis between polygenic risk scores and traits: practical guidelines and tutorial with an illustrative data set of schizophrenia by Itziar Irigoien, Patricia Mas-Bermejo, Patricia Mas-Bermejo, Sergi Papiol, Sergi Papiol, Sergi Papiol, Neus Barrantes-Vidal, Neus Barrantes-Vidal, Neus Barrantes-Vidal, Araceli Rosa, Araceli Rosa, Araceli Rosa, Concepción Arenas

“…With this guide, we intend to fill a gap in association studies between PRSs and a trait and to facilitate the analysis, obtaining statistically correct results. …”
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Inducing aortic aneurysm/dissection in zebrafish: evaluating the efficacy of β-Aminopropionic Nitrile as a model by Jiarui Zhang, Yaowen Liang, Weiyue Zeng, Xiaoyan Gao, Dingchen Wang, Cong Mai, Zhuoheng Lin, Haishan Zhao, Xin Li

“…Aortic aneurysm/dissection (AAD) poses a life-threatening cardiovascular emergency with complex mechanisms and a notably high mortality rate. …”
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Interpretive structural modeling (ISM) of risk management in Iran's construction industry by Hamed Shokri, Abbas Afrazeh

“…Also, according to (D-R), the lowest value, the risk dimension of laws and regulations, is the most effective dimension of risk management in Iran's construction industry.Originality/Value: The current research is new in terms of the subject area, i.e. in the field of the construction industry of Iran, and in terms of the location area, i.e. companies active in the field of the construction industry of New Tehran. The research gap that creates the space for innovation in the current research, according to the perspective of soft operations research, which is a tool for creating complex and new problems, is the use of Interpretive Structural Modeling (ISM) and DEMATEL. …”
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The intersection of stress, loneliness, and mental health attitudes in young multinational corporation employees by Thuy Thi Thanh LE, Ha-Chau TRAN-NGOC, Van-Nhi HO, Bao-Nhu NGUYEN-HOANG, Hoang-Anh Ngoc HO, Van-Anh TRAN-DO

“…Conclusion: These findings highlight the complex relationship between stress, loneliness, and workplace factors in young MNC workers. …”
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DIGITAL MOBILITY OF THE FUTURE SPECIALIST: CURRENT TRENDS by Leonov Maksym

“…It has been determined that mobility is a complex interdisciplinary category that can be characterized in broad socio-economic and narrow personal contexts. …”
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Prioritizing delirium risk factors in nursing: a cross-sectional study using the analytic hierarchy process by Özge Zeki, Perihan Güner, Mustafa Zeki, Mustafa Ozkaynak

“…Abstract Background Delirium is a complex neuropsychiatric syndrome characterized by acute and fluctuating disturbances in attention, cognition, and consciousness. …”
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Trade-offs from a family perspective: considerations in choosing between omalizumab and complementary alternative medicine for pediatric severe asthma by Hang Chen, Yan Xu, Yan Xu, Jian-Li Qiu, Jian-Li Qiu, Zhi-Wei Guan, Zhi-Wei Guan, Mu-Mu Wei, Mu-Mu Wei, Yi Zhang, Yi Zhang, Ji-Xiang Xu, Hong-Tao Cui

“…When faced with the choice between targeted biologics like omalizumab and widely used complementary alternative medicine (CAM), families navigate a complex decision-making process influenced by multiple factors. …”
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Evaluation of the ecological status of Posidonia oceanica meadows along the Calabrian Coasts: A multi-index approach by Faustino Scarcelli, Chiara Spadaro, Annamaria Ienco, Vincenzo Osso, Pietro Giovannelli, Silvestro Greco, Silvia Mazzuca, Amalia Piro

“…In doing so, the study addressed a significant gap in our knowledge of this important marine area. …”
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Beyond imperfect maps: Evidence for EUDR‐compliant agroforestry by Meine vanNoordwijk, Sonya Dewi, Peter A. Minang, Rhett D. Harrison, Beria Leimona, Andre Ekadinata, Paul Burgers, Maja Slingerland, Marieke Sassen, Cathy Watson, Jeffrey Sayer

“…In targeting ‘deforestation‐free’ trade, it forces a complex social–ecological reality into an oversimplified forest–non‐forest representation. …”
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A comprehensive overview of focused ion beam-scanning electron microscopy (FIB-SEM) applications for the evaluation of outer retina by Sanjay Ch, Rayne R. Lim, Shermaine W. Y. Low, Deana G. Grant, Sam Patterson, Aparna Ramasubramanian, Ashish K. Gadicherla, Shyam S. Chaurasia, Shyam S. Chaurasia

“…However, they are limited by their inability to image the complex three-dimensional (3D) structure layer-by-layer at a nanoscale resolution. …”
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A Transformer-LSTM-SVR hybrid model for AI-driven emotional optimization in NEV embedded interior systems by Zongming Liu, Xuhui Chen, Xinan Liang, Zhicheng Sun, Fengqi Yang, Wenwen Ou, Linwei Li, Xiayan Qin

“…This model addresses the complex nonlinear relationship between users’ emotional satisfaction and interior design attributes. …”
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The Digital-Sustainability Ecosystem: A conceptual framework for digital transformation and sustainable innovation by Anna Florek-Paszkowska, Anna Ujwary-Gil

“…It examines how emerging digital technologies, including artificial intelligence, blockchain, and the Internet of Things, drive sustainability transitions by serving as strategic enablers. Addressing a critical gap in the literature, this research focuses on the dynamic mechanisms and synergies that connect digital transformation with sustainable innovation within a complex ecosystem. …”
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Harnessing Advanced Imaging Technologies in Robotic Urological Surgery Requires Specialized and Structured Training by Enrico Checcucci, Stefano Puliatti, Gabriele Volpi, Gabriele Bignante, Francesco Porpiglia, Riccardo Campi, Daniele Amparore

“…Despite growing adoption, structured training programs tailored to 3D and AR applications remain underdeveloped. To address this gap, we conducted an online survey of participants from the 12th Techno Urology Meeting (2024) to evaluate the current use and training needs for these technologies. …”
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Optimization Problem for Probabilistic Time Intervals of Quasi-Deterministic Output and Self-Similar Input Data Packet Flow in Telecommunication Networks by G. I. Linets, R. A. Voronkin, G. V. Slyusarev, S. V. Govorova

“…To do this, it is required to apply complex probabilistic laws of distribution of self-similar flows. …”
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A recurrent YOLOv8-based framework for event-based object detection by Diego A. Silva, Kamilya Smagulova, Ahmed Elsheikh, Mohammed E. Fouda, Ahmed M. Eltawil

“…In particular, the ReYOLOv8 system effectively bridges the gap between biological principles of vision and artificial intelligence, enabling robust and efficient visual processing in dynamic and complex environments. …”
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Synergistic effect of magnetic magnetite and greigite nanoparticles dispersed pinewood biochar for aqueous lead(II) and cadmium(II) adsorption by Prashan M. Rodrigo, Raghava R. Kommalapati

“…Their remediation is complex in the aqueous phase. Biochar is a low-cost, environmentally friendly adsorbent material that exhibited a limited ability to adsorb Pb2+ and Cd2+. …”
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Exploring the approaches towards support of academic entrepreneurship: evidence from an emerging market by Marek Zinecker, Jan Pěnčík, Alena Kocmanová, Tomáš Meluzín, Adam P. Balcerzak, Michał Bernard Pietrzak

“…In this paper, we attempt to fill this gap while adopting a case study approach to examine the issue of what resources a prominent technical university operating in the emerging market of the Czech Republic transfers to academic ventures to utilise and commercialise university research results. …”
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Advancing Progressive Web Applications to Leverage Medical Imaging for Visualization of Digital Imaging and Communications in Medicine and Multiplanar Reconstruction: Software Deve... by Mohammed A. AboArab, Vassiliki T. Potsika, Alexis Theodorou, Sylvia Vagena, Miltiadis Gravanis, Fragiska Sigala, Dimitrios I. Fotiadis

“…This paper addresses this gap by leveraging PWAs for their offline access and enhanced performance. …”
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DNA/RNA-binding protein KIN17 supports esophageal cancer progression via resolving noncanonical STING activation induced by R-loop by Zichao Wei, Ning Zhao, Lu Kuang, Ji Cong, Sujuan Zheng, Yi Li, Zhihua Liu

“…Collectively, our findings identify KIN as a novel R-loop binding protein that facilitates the recruitment of the R-loop resolution complex and suppresses tumor-intrinsic innate immunity.…”
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The Transcriptomic Signature of Donkey Ovarian Tissue Revealed by Cross-Species Comparative Analysis at Single-Cell Resolution by Yu Tian, Yilin Niu, Xinhao Zhang, Tao Wang, Zhe Tian, Xiaoyuan Zhang, Jiachen Guo, Wei Ge, Shuqin Liu, Yujiang Sun, Jianjun Li, Wei Shen, Junjie Wang, Teng Zhang

“…Furthermore, an in vitro cumulus–oocyte complex model demonstrated the critical role of <i>GATM</i> in mammalian oocyte maturation. …”
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