Gene network centrality analysis identifies key regulators coordinating day-night metabolic transitions in Synechococcus elongatus PCC 7942 despite limited accuracy in predicting d... by Zachary Johnson, Zachary Johnson, David Anderson, Margaret S. Cheung, Margaret S. Cheung, Pavlo Bohutskyi, Pavlo Bohutskyi

“…The regulatory principles uncovered here advance our understanding of how cyanobacteria coordinate complex metabolic transitions and may inform metabolic engineering strategies for enhanced photosynthetic bioproduction from CO2.…”
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Decoupling Behavioral Domains via Kynurenic Acid Analog Optimization: Implications for Schizophrenia and Parkinson’s Disease Therapeutics by Diána Martos, Bálint Lőrinczi, István Szatmári, László Vécsei, Masaru Tanaka

“…This study advances the development of safer neuroactive compounds, bridging a critical gap between preclinical innovation and clinical translation. …”
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Symptom-related experience and sexual health of female patients with pulmonary arterial hypertension: protocol for a systematic review and qualitative meta-synthesis by Ye He, Zhu Yang, Lixiao Yang, Fangfang Ma

“…Introduction Pulmonary arterial hypertension (PAH) is a complex condition affecting quality of life, characterised by high blood pressure in the pulmonary arteries leading to heart strain. …”
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Seismicity characteristics and interseismic locking of the Anninghe Fault, Southwest China: Insights from long-term dense seismic array observations by Jun Li, Guoqing Zhang, Song Zhang, Qincai Wang, Chaoyong Peng, Zhen Lu, Shangwu Song, Ming Hao, Yun Zhou, Qingliang Wang, Lihua Fang

“…Our results reveal the complex structure of the ADZF, providing the detailed information of the dip angle and dip direction of different fault segments. …”
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WEGAN: a web-based community ecology platform by Gina P. Sykes, Gina P. Sykes, Louisa Normington, Jenna Poelzer, Shiyang Zhao, Dana Allen, Samuel Stuart, Eponine Oler, Komal Jot, Vasuk Gautam, Xin Zhao, Jianguo Xia, Glen C. Jickling, David S. Wishart, David S. Wishart, David S. Wishart, David S. Wishart

“…Community ecology studies how species interact in their ecosystems, influenced by environmental and phenotypic factors. Analyzing these complex interactions requires specialized software or proficiency in statistical programming. …”
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Investigating the role of rock weathering and clay mineralogy in landslide occurrences within the exposed Tertiary Formations in Rangamati area by Shakhawat Hossain, Mahmud Al Noor Tushar, Shariful Islam, Md. Zayed Abdur Razzak, Asif Alve, Tahmidur Rahman Junayed

“…Four primary types of landslides: flow, fall, slide, and complex—are identified across all formations in varying proportions. …”
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Spatial Beam Cleaning in Multimode GRIN Fibers: Polarization Effects by Mario Ferraro, Fabio Mangini, Mario Zitelli, Raphael Jauberteau, Yifan Sun, Pedro Parra-Rivas, Katarzyna Krupa, Alessandro Tonello, Vincent Couderc, Stefan Wabnitz

“…In this work, we fill this gap by reporting extensive experimental investigations of beam self-cleaning in multimode fibers, for beams with different input states of light polarization. …”
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Application of machine learning for predicting the incubation period of water droplet erosion in metals by Khaled AlHammad, Mamoun Medraj, Moussa Tembely

“…The incubation period—the initial phase before visible material loss occurs—is particularly crucial for maintenance planning and material selection yet remains challenging to predict accurately due to the complex interplay of material properties and impact conditions. …”
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Selection of the Process of Arc Welding of Sealing Surfaces of Power Valves with a Consumable Electrode in the Shielding Gas by D. V. Rogozin, V. A. Lenivkin

“…The presented research is intended to fill this gap. The objective of its authors is to select such a process of arc welding of beads on parts of the power valve trim with a consumable electrode in shielding gases, which would provide the best workability of the deposited metal.Materials and Methods. …”
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Impact of acoustic waves on rainfall distribution in acoustics-induced artificial rainfall technology by Mengyao WANG, Jiaye LI, Ji CHEN, Jinzhao WANG, Songdong SHAO

“…Rainfall in the second stage usually lasts for hours with random distribution, and the impact of acoustic waves may not be reflected in the rainfall distribution because of the complex cloud dynamics. These findings help fill the existing gap in understanding how artificial acoustic forcing interacts with precipitation processes over high-altitude regions.…”
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DCMC-UNet: A Novel Segmentation Model for Carbon Traces in Oil-Immersed Transformers Improved with Dynamic Feature Fusion and Adaptive Illumination Enhancement by Hongxin Ji, Jiaqi Li, Zhennan Shi, Zijian Tang, Xinghua Liu, Peilin Han

“…., carbon traces produced by surface discharge inside the transformer), the intelligent and efficient extraction of carbon trace features from complex backgrounds becomes critical for robotic inspection. …”
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Cardiac Repair and Clinical Outcomes of Stem Cell Therapy in Heart Failure: A Systematic Review and Meta-Analysis by Salman Muslem, Mariam AlTurani, Muhammad Bilal Maqsood, Maryam Al Qaseer

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Integrating mathematical analysis and biotechnological approaches for enhanced environmental management by Nussupov A. Aidarzhanovich, Yessimsiitova Z. Bekturovna, Abdreshov S. Nauryzbaevish, Nurjan Beisenbayuly, Sadykova N. Alaldunkyzy, Mukhitdinov Azamat, Ablaikhanova Nurzhaniyat, Lesova Z. Tureevna

“…The novelty of our work lies in its interdisciplinary nature, bridging the gap between biotechnology and mathematics to tackle complex environmental problems. …”
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A pilot study protocol of a relational coordination training intervention among healthcare professionals in an Army medical center by Sherita House, Susan M. Perkins, Melissa Miller, Tanekkia Taylor-Clark, Robin Newhouse

“…Abstract Background As patient care becomes more complex, high-quality communication and relationships among healthcare professionals are critical to coordinating care. …”
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Harnessing Beneficial Microbes for Drought Tolerance: A Review of Ecological and Agricultural Innovations by Grzegorz Mikiciuk, Tymoteusz Miller, Anna Kisiel, Danuta Cembrowska-Lech, Małgorzata Mikiciuk, Adrianna Łobodzińska, Kamila Bokszczanin

“…Collaborative efforts among academia, industry, and government are essential to bridge the gap between research and practical implementation. …”
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Effects of systemic challenges on agricultural development systems: a systematic review of perspectives by Enock Siankwilimba, Jacqueline Hiddlestone-Mumford, Md Enamul Hoque, Bernard Mudenda Hang’ombe, Chisoni Mumba, Oliver Jolezya Hasimuna, Sahya Maulu, Joseph Mphande, Gunawan Prayitno

“…In response to these complex challenges, leadership that fosters collaboration among stakeholders through private and public dialogue is crucial. …”
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Exploratory insights from the immuno-oncology hollow fiber assay: A pilot approach bridging In Vitro and In Vivo models by Tove Selvin, Malin Berglund, Anders Åkerström, Marco Zia, Jakob Rudfeldt, Malin Jarvius, Rolf Larsson, Claes R Andersson, Mårten Fryknäs

“…We developed the in vivo immuno-oncology Hollow Fiber Assay (HFA) to bridge the gap between simpler cell-based in vitro assays and more complex mouse models for immuno-oncology drug evaluation. …”
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An overview of natural coumarins (2016–2018): chemical structures and pharmacological activities by Ze-Dong Nan, Tao Liu, Jing Liu, Hui Zhang, Xiao-Yu Zhao, Yan Ge, Chong-Long Li

“…The coumarin derivatives display diverse structural characteristics, and their molecular skeleton can give rise to several complex subclasses. Pharmacological studies have demonstrated that coumarins exhibited a broad-spectrum of biological activities. …”
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The Role of Trees in Sand Dune Rehabilitation: Insights from Global Experiences by Lucian Dinca, Aurora Coca, Nicu Constantin Tudose, Mirabela Marin, Gabriel Murariu, Dan Munteanu

“…Our main focus was on the role of trees in stabilizing and rehabilitating these complex ecosystems. We analyzed 937 publications through a systematic bibliometric review and then proceeded to select 422 articles that met our criteria. …”
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Algorithm for Processing X-ray Images Using Fuzzy Logic by A. S. Mannaa

“…In some cases, orthopedists and surgeons have to manually refine images and adjust lines. This gap is filled by the presented work. The algorithm developed by the author is described. …”
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