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141
Loss of ARID1A leads to a cold tumor phenotype via suppression of IFNγ signaling
Published 2025-03-01“…We found ARID1A is a functional interactor of IRF1 by co-immunoprecipitation studies, and ARID1A silencing causes loss of activating chromatin marks at the IRF1 target gene CXCL10. …”
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142
PGC-1α Promotes mitochondrial biosynthesis and energy metabolism of goose fatty liver
Published 2025-01-01“…To investigate the functions of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) in the goose fatty liver, a total of 30 healthy 63-day-old male Landes geese were selected and randomly assigned to control group and overfeeding group. …”
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143
Longitudinal characterization of the metabolome of dairy cows transitioning from one lactation to the next: Investigations in fecal samples
Published 2025-05-01“…Overall, these results emphasize the complex interactions between dietary factors, liver and gastrointestinal function, and the gut microbiome in shaping the fecal metabolite profile of dairy cows. …”
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144
IMPACT OF MULTIPLE MYELOMA: REVEALING CLINICAL AND GENETIC ASPECTS
Published 2024-10-01“…The main symptoms are bone pain, anemia, leukocyte dysfunction and renal function alterations. To confirm the diagnosis, some additional tests are needed for therapeutic planning, including prothrombin time, activated partial thromboplastin time, fibrinogen, d-dimer, total bilirubin and fractions, alkaline phosphatase, transaminases and gamma-gt. …”
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145
Comparison of two surgical treatments for proximal femur fracture in elderly obese patients
Published 2022-11-01“…Using the advantages of hip arthroplasty is the most important factor of favorable outcome of treatment and life preservation for this complex group of patients.…”
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146
Preliminary Evidence for Lensing-induced Alignments of High-redshift Galaxies in JWST-CEERS
Published 2025-01-01“…On the chip scale, the average complex ellipticity 〈 e 〉 ∼ 10% is nonnegligible and beyond the level of our point-spread function (PSF) uncertainties. …”
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147
Hepatoprotective Therapy Efficacy in Obstructive Hepatobiliary Diseases: A Prospective Randomized Study
Published 2025-03-01“… Introduction and purpose Obstructive diseases of the hepatobiliary system present a complex set of clinical challenges characterized by impaired bile outflow and progressive hepatocellular damage. …”
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148
Finite Mixture Models: A Key Tool for Reliability Analyses
Published 2025-05-01“…As system complexity increases, accurately capturing true system reliability becomes increasingly challenging. …”
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149
Effects of an interprofessional care concept in nursing homes evaluated in the SaarPHIR project: A cluster-randomized controlled trial.
Published 2025-01-01“…Transfers are stressful for residents, and hospital stays can lead to infections and functional decline. Increasing the role of general practitioners and improving collaboration between professionals may reduce hospitalizations. …”
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150
BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.
Published 2010-01-01“…Recent in vitro studies suggest that BRIT1/MCPH1 functions as a novel key regulator in the DNA damage response pathways. …”
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151
A systematic study on complementary metal-oxide semiconductor technology (CMOS) and Internet of Things (IOT) for radioactive leakage detection in nuclear plant
Published 2023-09-01“…Within this paper, we have given brief descriptions of CMOS and IoT with their types, functions, methodology, and applications. CMOS is considered to be the most sophisticated and precise technology that can be employed to measure radiation leaks of all types (alpha rays, beta rays, gamma rays, and neutrons). …”
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152
The immune-related gene CD5 is a prognostic biomarker associated with the tumor microenvironment of breast cancer
Published 2025-01-01“…Abstract The occurrence and progression of breast cancer (BCa) are complex processes involving multiple factors and multiple steps. …”
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153
Elucidating the role of LGALS3BP in coronary atherosclerosis: integrating bioinformatics and machine learning for advanced insights
Published 2025-08-01“…Conclusions Our research elucidates the complex relationship between LGALS3BP and AS, positioning it as a potential novel biomarker for diagnosis and disease monitoring. …”
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154
Comprehensive N-glycosylation profiling of recombinant spike S1 protein from the wild-type SARS-CoV-2 and its variants
Published 2025-07-01“…UHPLC-TOF MS analysis revealed unoccupied N-glycosylation sites in S1-Gamma (N657), S1-Delta (N61), and S1-Lambda (N17, N61, N657), with N17 and N61 showing low glycan occupancy (0%-3.4%), suggesting these sites may lack glycan shield protection.DiscussionThis study provides a comprehensive N-glycosylation profile of the S1 protein across different variants, offering an essential structural basis for future vaccine development and research on viral functions.…”
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155
Characterization of Environmentally Friendly Gadolinium/Boron Flexible Thermal Neutron Absorbing Material
Published 2024-06-01“…Generally, lead containing materials, polyethylene or epoxy resin matrix composites, stainless steel or alloy, ceramic or concrete are commonly selected for biological shielding, so as to reduce the neutron or gamma radiations below the limit level. However, these shielding materials are not able to be well attached to the peripheries of nuclear equipments or instruments with complex shapes because of their rigidity. …”
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156
Case report: Endolymphatic sac tumor with blurred vision
Published 2025-01-01“…After surgery, most of the tumor was successfully resected while preserving neurological function well, and the residual tumor was treated with adjuvant gamma knife with good results.ConclusionELST is a rare, low-grade, locally aggressive tumor that is difficult to diagnose early. …”
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157
Effective antistress ligands lithium new generation
Published 2017-03-01“…To increase stress tolerance it is necessary to maintain the body's balance functions of the nervous, immune, endocrine and antioxidant systems of the monooxygenase. …”
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158
Identifying Priority Areas for Planning Urban Green Infrastructure: A Fuzzy Artificial Intelligence-Based Framework
Published 2025-04-01“…The system’s modular structure, use of triangular membership functions, and incorporation of the gamma operator allow for adaptable prioritization across different planning horizons. …”
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159
γδT cells, a key subset of T cell for cancer immunotherapy
Published 2025-03-01“…This review highlights the key mechanisms, functions, and strategies to harness the potential of γδT cells for effective tumor immunotherapy.…”
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160
Clustering Electrophysiological Predisposition to Binge Drinking: An Unsupervised Machine Learning Analysis
Published 2024-11-01“…We used hierarchical agglomerative UML techniques based on Ward's minimum variance criterion to clusterize relations between power spectrum and functional connectivity and alcohol consumption, based on similarity in their correlations, in frequency bands from theta to gamma. …”
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