Novel rapid molecular diagnosis methods for comprehensive genetic analysis of 21-hydroxylase deficiency by Yanjie Xia, Feng Yu, Ying Bai, Lili Jiang, Panlai Shi, Zhengwen Jiang, Xiangdong Kong

“…Results Among the 113 21-OHD patients, 95.6% of the affected alleles were detected accurately by SNaPshot and CNVplex. Prevalent mutations were detected in 69.5% of the alleles; 62.4% of alleles contained pseudogene-derived micro-conversions, 1.8% contained nonpseudogene-derived mutations, and 5.3% contained complex variations resulting from multiple recombinations between CYP21A2 and CYP21A1P. …”
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Recovery in personality disorders: the development and preliminary testing of a novel natural language processing model to identify recovery in mental health electronic records by Giouliana Kadra-Scalzo, Jaya Chaturvedi, Oliver Dale, Richard D. Hayes, Lifang Li, Shaza Mahmood, Jonathan Monk-Cunliffe, Angus Roberts, Paul Moran

“…Yet, investigating non-symptomatic recovery in the field of personality disorders has been particularly challenging due to complexities in capturing the occurrence of recovery. …”
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Reconstructed hyperspectral imaging for in-situ nutrient prediction in pine needles by Yuanhang Li, Yuanhang Li, Jun Du, Jun Du, Chuangjie Zeng, Chuangjie Zeng, Yongshan Wu, Yongshan Wu, Junxian Chen, Junxian Chen, Teng Long, Teng Long, Yongbing Long, Yongbing Long, Yubin Lan, Yubin Lan, Xiaoliang Che, Tianyi Liu, Jing Zhao, Jing Zhao

“…It facilitates efficient in situ nutrient detection and offers a promising tool for sustainable forestry development.…”
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Implementing Customized Electronic Quality Checklists to Reduce Errors and Improve Workflow in Radiotherapy by Zaheeda Mulla, Victor J. Joseph John, Rania Hashem, Hatim Z. Almarzouki, Abdullah Almohamad, Mohammad Attar, Hane Muamenah, Hanadi F. Habibullah, Hussam Hijazi

“…PURPOSEAdvancements in radiation oncology have improved treatment precision and effectiveness but increased procedural complexity and error risk because of higher patient volumes. …”
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Neural network quantification for solar radiation prediction: An approach for low power devices by Brenda Alejandra Villamizar-Medina, Angelo Joseph Soto Vergel, Byron Medina-Delgado, Darwin Orlando Cardozo-Sarmiento, Dinael Guevara-Ibarra, Oriana Alexandra Lopez-Bustamante

“…Quantization enables complex predictive models to run on low-cost, energy-efficient devices, thereby democratizing advanced prediction technologies for critical applications like solar energy generation. …”
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Establishing a universal IVRP method for quadrivalent HPV vaccines to replace in vivo potency tests by Jinpan Hu, Zijing Jia, Meng Wang, Lingling Nie, Wangjun Fu, Qingfeng Zhang, Haiyang Qin, Jianhui Nie, Xiaoyu Xu, Lingjie Xu, Fengze Wang, Yingping Chen, Bo Xing, Tao Li, Danfeng Li, Shaowei Li, Ningshao Xia, Xiangxi Wang, Weijin Huang

“…The IVRP results were correlated with potency data from mouse models, offering an efficient alternative to in vivo potency experiments.…”
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Simple Clinical Prediction Rules for Identifying Significant Liver Fibrosis: Evaluation of Established Scores and Development of the Aspartate Aminotransferase-Thrombocytopenia-Alb... by Puwitch Charoenchue, Jiraporn Khorana, Apichat Tantraworasin, Suwalee Pojchamarnwiputh, Wittanee Na Chiangmai, Amonlaya Amantakul, Taned Chitapanarux, Nakarin Inmutto

“…<b>Conclusions:</b> The ATA score offers a straightforward and efficient method for detecting significant fibrosis, demonstrating comparable diagnostic capability to APRI and FIB-4, while being more user-friendly in clinical practice. …”
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Comparison between inductively coupled plasma-mass spectrometry and benchtop X-ray fluorescence performance for trace elemental exposure in rat tissues by Kolawole E. Adesina, Stefano A. Parducci, Joseph D. Brain, Ramon M. Molina, Marc Weisskopf, Aaron J. Specht

“…However, ICP-MS is often limited by its complexity, cost, and time-intensive nature. Methods: This study investigates the feasibility of benchtop X-ray fluorescence (XRF) as an efficient alternative for trace elemental analysis in rat tissues, offering comparable quantification capabilities with enhanced operational simplicity. …”
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Residual stresses in cold-formed steel sections: An overview of influences and measurement techniques by Ayad Mutafi, J.M. Irwan, Noorfaizal Yidris, Abdullah Faisal Alshalif, Yazid Saif, Hamdi Abdulrahman, Ala Mutaafi, Yasser Yahya Al-Ashmori, Mugahed Amran, Nelson Maureira-Carsalade, Siva Avudaiappan

“…The study concludes that while analytical methods are effective, they become complex when accounting for material anisotropy. Laboratory techniques provide reliable measurements but are limited in detecting through-thickness residual stresses. …”
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Deep Learning-Based Fault Diagnosis via Multisensor-Aware Data for Incipient Inter-Turn Short Circuits (ITSC) in Wind Turbine Generators by Qinglong Wang, Shihao Cui, Entuo Li, Jianhua Du, Na Li, Jie Sun

“…These faults can cause fluctuations in the output voltage, frequency, and power of wind turbines, eventually leading to overheating, equipment damage, and rising maintenance costs if not detected early. Although significant progress has been made in condition monitoring, the current methods still fall short of the robustness required for early fault diagnosis in complex operational settings. …”
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Modulation of fibroblast behavior by Leishmania: a pathway to understanding disease progression in cutaneous leishmaniasis by Tarcisio Navegante de Queiroz Filho, Brenda Furtado Costa, Ana Paula Drummond Rodrigues

“…Interestingly, both the promastigote and amastigote forms of the parasite have also been detected in fibroblasts, revealing the complex interactions during the infection. …”
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Malarial pigment-induced lipoperoxidation, inhibited motility and decreased CCR2 and TNFR1/2 expression on human monocytes by Oleksii Skorokhod, Valentina Barrera, Elena Valente, Daniela Ulliers, Koji Uchida, Evelin Schwarzer

“…Objective: Malaria remains an important life-threatening disease that provokes a complex immune response, marked by an initial immune boost followed by long-term suppression, warranting further study. …”
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Swift Observations of Mrk 421 in Selected Epochs. IV. Physical Implications of X-Ray Flaring Activity and Features of Relativistic Magnetic Reconnection in 2018 April–2023 December... by B. Kapanadze, A. Gurchumelia, M. Aller

“…The UV and γ -ray variabilities demonstrated weak correlations with the X-ray flaring activity, which is not consistent with simple synchrotron self-Compton models and requires more complex particle acceleration and emission scenarios.…”
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Novel Epigenetics Control (EpC) Nanocarrier for Cancer Therapy Through Dual-Targeting Approach to DNA Methyltransferase and Ten-Eleven Translocation Enzymes by Risa Mitsuhashi, Kiyoshi Sato, Hiroyoshi Kawakami

“…The formation of core–shell nanoparticles and complexation with pDNA were investigated and optimized by dynamic light scattering, zeta potential measurement, and agarose gel electrophoresis. …”
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Improving the Principles of Identifying Critical Requirements for the Assembly of High-Precision Products by A. V. Nazaryev, P. Yu. Bochkarev

“…The application of this technique makes it possible to increase the reliability of the source information obtained during the implementation of an enlarged block of design procedures, as well as the validity and efficiency of identifying rational manufacturing technologies at subsequent stages of the system implementation, while providing the specified quality, accuracy of products, and reducing the complexity and cost of their manufacture.…”
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A comprehensive suite for extracting neuron signals across multiple sessions in one-photon calcium imaging by Pablo Vergara, Yuteng Wang, Sakthivel Srinivasan, Zhe Dong, Yu Feng, Iyo Koyanagi, Deependra Kumar, Yoan Chérasse, Toshie Naoi, Yuki Sugaya, Takeshi Sakurai, Masanobu Kano, Tristan Shuman, Denise Cai, Masashi Yanagisawa, Masanori Sakaguchi

“…CaliAli performs computationally efficient signal extraction from concatenated video sessions that enhances the detectability of weak calcium signals. …”
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Optimizing CNN-Based Diagnosis of Knee Osteoarthritis: Enhancing Model Accuracy with CleanLab Relabeling by Thomures Momenpour, Arafat Abu Mallouh

“…The substantial enhancement in model performance is primarily attributed to Cleanlab’s robust ability to detect and correct mislabeled instances, thereby improving the overall quality and reliability of the training data and enabling the model to better learn and capture complex radiographic patterns associated with KOA. …”
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Review of online quality control for laser directed energy deposition (LDED) additive manufacturing by Long Ye, Hao Xue, Zhaosheng Li, Yichang Zhou, Guangyu Chen, Fangda Xu, Ruslan Melentiev, Stephen Newman, Nan Yu

“…Laser directed energy deposition (LDED) is an emerging branch of metal-based additive manufacturing (AM) processes, offering unprecedented capabilities for high-performance fabrication with complex geometries and near-net shapes. This technology is gathering increasing attention from industries such as biomedical, automotive, and aerospace. …”
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Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…Our findings provide the first demonstration that TXA efficiently inhibits MSC-driven plasmin generation by competitively blocking plasminogen binding to the uPA•uPAR complex at the cell plasma membrane.DiscussionWe propose that plasmin formation on MSCs may be involved in pathological processes such as endometrial hemorrhage (metrorrhagia and Post-Partum Hemorrhage), autoimmune and ischaemic diseases, as well as cancer. …”
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Cellulose/TiO₂ Humidity Sensor by Susana Devesa, Zohra Benzarti, Madalena Costa, Diogo Cavaleiro, Pedro Faia, Sandra Carvalho

“…Resistivity-type humidity sensors, which detect changes in electrical resistance in response to variations in environmental humidity, have garnered significant interest due to their widespread application in industry, agriculture, and daily life. …”
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