Development and retrospective validation of an artificial intelligence system for diagnostic assessment of prostate biopsies: study protocol by Martin Eklund, Brett Delahunt, Lars Egevad, Hemamali Samaratunga, Mattias Rantalainen, Marcello Gambacorta, Einar Gudlaugsson, Bodil Ginnerup Pedersen, Xiaoyi Ji, Karina Dalsgaard Sørensen, Kelvin Szolnoky, Nita Mulliqi, Anders Blilie, Henrik Olsson, Matteo Titus, Geraldine Martinez Gonzalez, Sol Erika Boman, Masi Valkonen, Svein Reidar Kjosavik, José Asenjo, Paolo Libretti, Marcin Braun, Radzislaw Kordek, Roman Łowicki, Kristina Hotakainen, Päivi Väre, Benedicte Parm Ulhøi, Pekka Ruusuvuori, Toyonori Tsuzuki, Emilius Adrianus Maria Janssen, Kimmo Kartasalo

“…Many pathology departments are also facing an increasingly unsustainable workload due to rising prostate cancer incidence and a decreasing pathologist workforce coinciding with increasing requirements for more complex assessments and reporting. Digital pathology and artificial intelligence (AI) algorithms for analysing whole slide images show promise in improving the accuracy and efficiency of histopathological assessments. …”
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Convergent construct validity and test-retest reliability of both German versions of the original and the revised Niigata PPPD Questionnaire: NPQ and NPQ-R by Sarah Chételat, Sarah Chételat, Eve-Yaël Gerber, Eve-Yaël Gerber, Sarah El Khadlaoui, Frank Behrendt, Frank Behrendt, Michaela Stark, Michaela Stark, Stefan Schädler, Stefan Schädler, Maximilian Maywald, Lena Fabritius, Johannes Gerb, Johannes Gerb, Denis Grabova, Wiebke Trost, Andreas Zwergal, Andreas Zwergal, Ralf Strobl, Ralf Strobl, Katrin Parmar, Katrin Parmar, Hans Ulrich Gerth, Hans Ulrich Gerth, Leo H. Bonati, Leo H. Bonati, Leo H. Bonati, Sandra Becker-Bense, Corina Schuster-Amft, Corina Schuster-Amft, Corina Schuster-Amft

“…Characteristic provocation factors are moving or complex visual stimuli and exclusion of organic diseases. …”
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Timescales of Polycyclic Aromatic Hydrocarbon and Dust Continuum Emission from Gas Clouds Compared to Molecular Gas Cloud Lifetimes in PHANGS-JWST Galaxies by Jaeyeon Kim, Mélanie Chevance, Lise Ramambason, Kathryn Kreckel, Ralf S. Klessen, Daniel A. Dale, Adam K. Leroy, Karin Sandstrom, Ryan Chown, Thomas G. Williams, Sumit K. Sarbadhicary, Francesco Belfiore, Frank Bigiel, Enrico Congiu, Oleg V. Egorov, Eric Emsellem, Simon C. O. Glover, Kathryn Grasha, Annie Hughes, J. M. Diederik Kruijssen, Janice C. Lee, Debosmita Pathak, Ismael Pessa, Erik Rosolowsky, Jiayi Sun, Jessica Sutter, David A. Thilker

“…After star formation is detected in H α , mid-IR emission persists for 3–7 Myr during the stellar feedback phase, covering 70%–80% of the H α emission. …”
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Research advances on reisistance to kiwifruit bacterial canker by ZHANG Min, SUN Leiming, FU Rong, LIN Miaomiao, WANG Ran, QI Xiujuan

“…Since the first KBC was detected in Japan in 1984, it has been discovered in various countries around the world. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…While HCPs recognised complexities of the DPC, data also support the feasibility of delivery by non-allergy specialists with appropriate resources, training, facilities, local policies and governance framework and escalation or referral pathways to allergy specialists. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In line with Medical Research Council guidance for complex interventions, we also conducted an integrated multimethod multiperspective (from patients, suitable informants and NHS professionals) process evaluation. …”
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Individual muscle strengths in rehabilitation outcomes of distal radius fracture by Lunjian Li, Xuanchi Liu, Lihai Zhang

“…The non-linear relationship of contract forces to the scaling coefficients indicates the complexity of the musculoskeletal system. …”
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Accumulation of Reducing Sugars by Small-leaved Linden Flowers (Tilia cordata Miller, 1768) in the Voronezh Region of Russia by N. A. Dyakova, A. I. Slivkin, S. P. Gaponov, E. A. Bobina, L. A. Shishorina

“…At the same time, it is possible that saccharide complexes might have reacted with heavy metals instead of the complexing agent when levels of reducing sugars in the samples were quantitatively determined. …”
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Hierarchical diagnostic approach for performance problems in cloud computing platforms by MI Hai-bo1, WANG Huai-min1, CAI Hua2, YIN Gang1, ZHOU Qi2, SUN Ting-tao2, ZHOU Yang-fan3

“…A hierarchical diagnosis approach,namely Magnifier,was proposed,which models the execution path graph of a user request as component layer,module layer and function layer,and detects anomalies from higher layer to lower layer separately.Extensive experiments were conducted on the Alibaba cloud computing platform.The results indicate that,under the conditions of large volume of data and high complexity of execution paths,Magnifier can accurately and efficiently locate the prime causes of performance degradation.…”
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Utilizing process mining in quality management: A case study in radiation oncology. by Mohammad Bakhtiari

“…Radiation oncology is known for its complexity, inherent risks, and sheer volume of data. …”
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Load identification method based on one class classification combined with fuzzy broad learning by Wang Yi, Wang Xiaoyang, Li Songnong, Chen Tao, Hou Xingzhe, Fu Xiuyuan

“…Considering the recognition rate and model complexity, the fuzzy broad learning system is used to classify and recognize the screened samples. …”
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Sparse Cumulants Fitting for Direction-of-Arrival Estimation without Redundancy by Shuang Li, Xiaoxiao Jiang, Sai Ma, Yingguan Wang

“…Simulation results are presented to illustrate the effectiveness and efficiency of the proposed method.…”
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The Design and Research of the Bolt Loosening Monitoring System in Combine Harvesters Based on Wheatstone Bridge Circuit Sensor by Yi Lian, Bangzhui Wang, Meiyan Sun, Kexin Que, Sijia Xu, Zhong Tang, Zhilong Huang

“…Utilizing LoRa wireless communication, the system effectively overcomes the wiring complexity and deployment difficulties of traditional agricultural machinery bolt monitoring systems. …”
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Multi-Objective Optimization of Manufacturing Process Using Artificial Neural Networks by Katarína Marcineková, Andrea Janáková Sujová

“…This multi-objective optimizing solution facilitates enhanced process efficiency. By integrating Systems Theory, Complexity Theory, and adaptive management, this research advances sustainable process improvements by minimizing resource use, reducing waste, and enhancing overall system efficiency.…”
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Intronomics-MIP: a snakemake pipeline for analyzing multilocus intron polymorphisms in species identification and population genomics by A. Scapolatiello, E. Boscari, L. Schiavon, N. Vitulo, L. Congiu

“…These MIPs serve as powerful multiple-allelic markers, primarily useful for distinguishing species, identifying cryptic species, disentangling species complexes and detecting hybridization, but can also be informative for assessing population structure without prior species knowledge. …”
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Background reference frame generation method for surveillance video based on image block codebook model by Wei ZHANG, Yu WANG, Xinyi CHEN, Yanwen WANG, Qingyang JING, Weimin LEI

“…To solve the problems that the background reference frames are seriously contaminated by the foreground, and the bit rate increases suddenly incurred by the one-time transmission of the background frames, a progressive background frame generation method with image block as the basic unit was proposed for surveillance video application.An image block codebook model based on clustering was formulated.The image blocks at the same position in the video sequence were effectively clustered by using perceptual hash-based element matching.The background symbol was accurately detected by using the characteristics of the background image area.A complete background frame was produced by extracting the background blocks in different frames based on the codebook model.Experimental results demonstrate that the proposed method achieves 17.89% coding efficiency for luma component compared with standard HM16.20, and can effectively improve the quality of the produced background reference frame.Besides, the proposed method complexity meets the real-time requirements of video applications.…”
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The Direct Gene Injection Using of Egg Yolk Emulsion as Carrier and its Comparison with Liposomes. by Baghdad Science Journal

“…The efficiency of egg yolk emulsion in coating DNA and its delivery across cellular membranes was evaluated in comparison with liposomes DOPE . …”
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Predicting and comparing transcription start sites in single cell populations. by Shiwei Fu, Wei Vivian Li

“…It employs a Binomial generalized linear mixed model to accurately and efficiently detect differential TSS usage. We demonstrate the utility of scTSS through its application in analyzing transcriptional initiation from single-cell data of two distinct diseases. …”
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CARD8 and NLRP1 undergo autoproteolytic processing through a ZU5-like domain. by Andrea D'Osualdo, Christian X Weichenberger, Roland N Wagner, Adam Godzik, John Wooley, John C Reed

“…The "Function to Find Domain" (FIIND)-containing proteins CARD8 (Cardinal; Tucan) and NLRP1 (NALP1; NAC) are well known components of inflammasomes, multiprotein complexes responsible for activation of caspase-1, a regulator of inflammation and innate immunity. …”
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PATIENTS REFERRED FOR BLEEDING SYMPTOMS OF UNKNOWN CAUSE: DOES EVALUATION OF THROMBIN GENERATION CONTRIBUTE TO DIAGNOSIS? by Elena Holm, Eva Zetterberg, Susanna Lövdahl, Erik Berntorp

“…In conclusion, the complexity of the mechanisms underlying clinical bleeding complicates the ability to use TG tests as reliable predictors of bleeding. …”
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