Quantification of oleanolic acid and apigenin in biological matrices following intraperitoneal administration of co-loaded nanoformulations: Method validation and biodistribution s... by Amna Naz, Sadia Haider, Mavra Rana, Neelum Malik, Attia Afzal, Muhammad Farooq, Muhammad Sarfraz

“…The validated HPLC-UV bioanalytical method was effectively applied in quantification, stability, and pharmacokinetic studies of co-loaded nanoformulations of OA and APG with particle size 163 nm. The entrapment efficiency for OA was 93.95 ± 3.50 %, and for APG, it was 94.5 ± 2.31 % in combined nanoformulation, establishing it as a promising analytical technique for detecting these anticancer agents in complex matrices such as blood, plasma, and polymeric systems.…”
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DualHet-YOLO: A Dual-Backbone Heterogeneous YOLO Network for Inspection Robots to Recognize Yellow-Feathered Chicken Behavior in Floor-Raised House by Yaobo Zhang, Linwei Chen, Hongfei Chen, Tao Liu, Jinlin Liu, Qiuhong Zhang, Mingduo Yan, Kaiyue Zhao, Shixiu Zhang, Xiuguo Zou

“…Meanwhile, it reduces model parameters by 14.6% and computational complexity by 29.2%, achieving a synergistic optimization of accuracy and efficiency. …”
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Attack scenarios reasoning,hypothesizing and predicting based on capability transition model by TIAN Zhi-hong1, ZHANG Wei-zhe1, ZHANG Yong-zheng2, ZHANG Hong-li 1, LI Yang2, JIANG Wei1

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From mechanism to applications: Advanced microneedles for clinical medicine by Yuqing Yang, Haifu Sun, Xiao Sun, Yu Wang, Fan Xu, Wenyu Xia, Liang Chen, Manyi Li, Tianke Yang, Yusen Qiao, Dechun Geng

“…In light of the potential limitations of conventional drug delivery, including low drug bioavailability and insufficient therapeutic efficiency, as well as the financial burden and discomfort associated with conventional detection, there is a thirst for alternatives. …”
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Investigation of the pathogenic potential and the possibility of cross-species transmission of H5 avian influenza viruses detected on the territory of the Russian Federation in 201... by Nikolay G. Zinyakov, Alena D. Grekhneva, Artem V. Andriyasov, Evgeniya V. Ovchinnikova, Nelli A. Guseva, Anton A. Kozlov, Zoya B. Nikonova, Pavel D. Zhestkov, Dmitry B. Andreychuk, Ilya A. Chvala

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A reliable approach for identifying acute lymphoblastic leukemia in microscopic imaging by Mimosette Makem, Levente Tamas, Lucian Bușoniu

“…The experimental results indicate that the proposed model is both efficient and robust, even when subjected to additional Gaussian noise. …”
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Clinical application of metagenomic next-generation sequencing in etiologic diagnosis of severe pneumonia in adults by Zhen-Chuan Xing, Hua-Zheng Guo, Peng Zhen, Ting Ao, Ming Hu

“…The detection efficiencies of different methods were compared and the associated pathogen profiles were analyzed.ResultsAmong the 132 patients, there were 92 males and 40 females, with a total of 52 deaths. …”
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Red Tide Detection Method Based on a Time Series Fusion Network Model: A Case Study of GOCI Data in the East China Sea by Tianhong Ding, Zhiqiang Xu, Yunjie Wang, Qinglian Hou, Xiangyong Liu, Fengshuang Ma

“…Experimental results demonstrate that CSF-RTDNet achieves robust detection of red tides with complex boundaries and continuous temporal patterns, attaining an accuracy of 95.89%, precision of 93.03%, recall of 96.34%, and a Kappa coefficient of 0.95. …”
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A Method for Recognizing Dead Sea Bass Based on Improved YOLOv8n by Lizhen Zhang, Chong Xu, Sai Jiang, Mengxiang Zhu, Di Wu

“…Therefore, it is necessary to promptly detect dead fish and take countermeasures. Existing object detection algorithms, when applied to the task of detecting dead sea bass, often suffer from excessive model complexity, high computational cost, and reduced accuracy in the presence of occlusion. …”
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Microplastics in soil: a comprehensive review of analytical techniques by Sedat Gündoğdu, Muhittin Onur Akça, Mehmet Gursoy, Murat Yılmaz, Xiaoyu Zhang, Xiaoyu Zhang, Andrés Rodríguez-Seijo, Andrés Rodríguez-Seijo, Aisha Bibi, Maria Luisa Di Gioia, Milica Velimirovic

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Nitrate Nitrogen Quantification via Ultraviolet Absorbance: A Case Study in Agricultural and Horticultural Regions in Central China by Yiheng Zang, Jing Chen, Muhammad Awais, Mukhtar Iderawumi Abdulraheem, Moshood Abiodun Yusuff, Kuan Geng, Yongqi Chen, Yani Xiong, Linze Li, Yanyan Zhang, Vijaya Raghavan, Jiandong Hu, Junfeng Wu, Guoqing Zhao

“…The ultraviolet (UV) dual-wavelength method is widely used for NO₃⁻-N detection, but interference from complex soil organic matter affects its accuracy. …”
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An enzyme-free electrochemical biosensor for sensitive and specific detection of microRNA-21 based on target recycling amplification and non-linear hybridization chain reaction by Jing Guo, Shou-feng Zhao, Shuang Chen, Wei-qing Song, Li-qun Li

“…Abstract A novel electrochemical biosensor with high amplification efficiency was explored for serum microRNA-21 (miRNA-21) detection. …”
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Identification of leaves of wild Ussurian Pear (Pyrus ussuriensis) based on YOLOv10n-MCS by Niman Li, Niman Li, Xingguang Dong, Yongqing Wu, Luming Tian, Ying Zhang, Hongliang Huo, Dan Qi, Jiayu Xu, Chao Liu, Zhiyan Chen, Yulu Mou

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Performance Evaluation of YOLOv11 and YOLOv12 Deep Learning Architectures for Automated Detection and Classification of Immature Macauba (<i>Acrocomia aculeata</i>) Fruits by David Ribeiro, Dennis Tavares, Eduardo Tiradentes, Fabio Santos, Demostenes Rodriguez

“…Inference throughput averaged 3.9 ms per image for YOLOv11x and 6.7 ms for YOLOv12x, highlighting a trade-off between speed and architectural complexity. Fused model representations revealed optimized layer fusion and reduced computational overhead (GFLOPs), facilitating efficient deployment. …”
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An FPGA-Based SiNW-FET Biosensing System for Real-Time Viral Detection: Hardware Amplification and 1D CNN for Adaptive Noise Reduction by Ahmed Hadded, Mossaad Ben Ayed, Shaya A. Alshaya

“…Performance evaluations confirmed the proposed system’s capability to enhance the SNR significantly while maintaining a compact and energy-efficient design suitable for portable diagnostics. …”
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Underwater Side-Scan Sonar Target Detection: An Enhanced YOLOv11 Framework Integrating Attention Mechanisms and a Bi-Directional Feature Pyramid Network by Junhui Zhu, Houpu Li, Min Liu, Guojun Zhai, Shaofeng Bian, Ye Peng, Lei Liu

“…To address these issues, this paper proposes the ABFP-YOLO model, which was designed to enhance the accuracy of underwater target detection. Specifically, the bi-directional feature pyramid network (BiFPN) structure is integrated into the model to efficiently fuse the features of different scales, significantly improving the capability of the network to recognize targets of varying scales, especially small targets in complex scenarios. …”
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Analysis and Selection Method for Radar Echo Features in Challenging Scenarios by Yunlong Dong, Xiao Luo, Hao Ding, Ningbo Liu, Zheng Cao

“…These findings provide a reference for joint feature detection in complex scenarios. To optimize feature application, the Spearman correlation coefficient matrix was transformed into a generalized distance matrix, and spectral clustering was used to group features with strong correlations. …”
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A Method for Predicting Coal-Mine Methane Outburst Volumes and Detecting Anomalies Based on a Fusion Model of Second-Order Decomposition and ETO-TSMixer by Qiangyu Zheng, Cunmiao Li, Bo Yang, Zhenguo Yan, Zhixin Qin

“…These limitations include the complexity of the models and their poor ability to generalize. …”
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Core–Shell Magnetic Gold Nanoparticles with Chitosan Coating as a SERS Substrate: A Rapid Detection Strategy for Malachite Green Contamination in Aquatic Foods by Yihui Yang, Tao Huang, Sijia Hu, Hang Ye, Jiali Xing, Shengnan Zhan

“…In this study, we developed a novel SERS-active magnetic substrate (MBs@CS@AuNPs) for detecting malachite green (MG) in aquatic products, including shrimp, cod, and aquaculture water. …”
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Multi-scale target intelligent detection method for coal, foreign object and early damage of conveyor belt surface under low illumination and dust fog by Hongwei FAN, Jinpeng LIU, Xiangang CAO, Chao ZHANG, Xuhui ZHANG, Man LI, Hongwei MA, Qinghua MAO

“…Finally, a lightweight and efficient channel attention mechanism is introduced into the backbone network and feature fusion network to improve channel utilization and early damage detection accuracy. …”
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