Addressing the dynamic nature of reference data: a new nucleotide database for robust metagenomic classification by Jose Manuel Martí, Car Reen Kok, James B. Thissen, Nisha J. Mulakken, Aram Avila-Herrera, Crystal J. Jaing, Jonathan E. Allen, Nicholas A. Be

“…This approach is crucial for ensuring accuracy and reliability of metagenomic analysis, especially as databases continue to expand in size and complexity.IMPORTANCEAccurately identifying the diverse microbes present in a sample, whether from the human gut, a soil sample, or a crime scene, is crucial for fields ranging from medicine to environmental science. …”
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Expanding SCINTIX Biology-Guided Radiotherapy Beyond Lung and Bone: A Planning Feasibility and Dosimetric Study on the RefleXion X1 System by Haozhao Zhang MSc, Grant Gibbard MSc, Chenyang Shen PhD, Thomas I. Banks PhD, Hao Peng PhD, Angela Da Silva PhD, Gopinath Kuduvalli PhD, Todd A. Aguilera MD, PhD, Tu Dan MD, Shahed N. Badiyan MD, Kenneth Westover MD, PhD, David J. Sher MD, Aurelie Garant MD, Raquibul Hannan MD, PhD, Steve B. Jiang PhD, Orhan K. Oz MD, PhD, Robert D. Timmerman MD, Bin Cai PhD

“…Statistical analyses examined relationships between dPET standardized uptake value (SUV), PET-derived parameters, planning target volume (PTV) characteristics, and plan complexity. Results BgRT plans were successfully generated for all lesions. …”
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Using natural experiments to evaluate population health interventions: a framework for producers and users of evidence by Peter Craig, Mhairi Campbell, Manuela Deidda, Ruth Dundas, Judith Green, Srinivasa Vittal Katikireddi, Jim Lewsey, David Ogilvie, Frank de Vocht, Martin White

“…Design and planning An adaptation of the MRC/NIHR framework, for the development and evaluation of complex interventions, provides a structure for planning and conducting a natural experimental evaluation and highlights the value of applying a complex systems perspective for the evaluation. …”
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Advancements and challenges in personalized neoantigen-based cancer vaccines by Parminder Singh, Parminder Singh, Mahalaqua Nazli Khatib, Roopashree R, Mandeep Kaur, Manish Srivastava, Amit Barwal, G. V. Siva Rajput, Pranchal Rajput, Rukshar Syed, Gajendra Sharma, Sunil Kumar, Muhammed Shabil, Sakshi Pandey, Manvinder Brar, Ganesh Bushi, Rachana Mehta, Sanjit Sah, Sanjit Sah, Sanjit Sah, Khang Wen Goh, Khang Wen Goh, Prakasini Satapathy, Prakasini Satapathy, Abhay M. Gaidhane, Shailesh Kumar Samal

“…Despite advancements, accurately predicting which neoantigens will elicit strong immune responses remains challenging due to tumor variability and the complexity of immune system interactions. This necessitates further refinement of bioinformatics tools and predictive models. …”
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Disparities in Postoperative Pain Management: A Scoping Review of Prescription Practices and Social Determinants of Health by Aidan Snell, Diana Lobaina, Sebastian Densley, Elijah Moothedan, Julianne Baker, Lama Al Abdul Razzak, Alexandra Garcia, Shane Skibba, Ayden Dunn, Tiffany Follin, Maria Mejia, Panagiota Kitsantas, Lea Sacca

“…<b>Background</b>: Opioid analgesic therapy has been traditionally used for pain management; however, the variability in patient characteristics, complexity in evaluating pain, availability of treatment within facilities, and U.S. physicians overprescribing opioids have contributed to the current opioid epidemic. …”
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Cause and Risk Factors of Delay Related to Neonatal Death in Afghan Immigrant Neonates Living in Tehran Province, Iran by Nahid Akbari, Leila Khedmat, Mansoureh Jamshidimanesh, Maryam Kashanian, Mohammad Javanbakht, Maziar Moradi-Lakeh, Ameneh Akhundi

“…These findings emphasize the imperative of implementing targeted interventions to support Afghan mothers and their neonates by enhancing access to comprehensive antenatal care, promoting health literacy, addressing maternal health complexities, and raising awareness about neonatal morbidity risk factors.…”
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Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness by Karamoko Niaré, Karamoko Niaré, Rebecca Crudale, Abebe A. Fola, Abebe A. Fola, Neeva Wernsman Young, Victor Asua, Victor Asua, Melissa D. Conrad, Pierre Gashema, Anita Ghansah, Stan Hangi, Deus S. Ishengoma, Deus S. Ishengoma, Jean-Baptiste Mazarati, Ayalew Jejaw Zeleke, Philip J. Rosenthal, Abdoulaye A. Djimdé, Abdoulaye A. Djimdé, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jeffrey A. Bailey, Jeffrey A. Bailey

“…The MIPs were balanced to produce more a uniform and higher depth of coverage at low parasitemia (100 parasites/μL) along with MIPs targeting antimalarial drug resistance genes. …”
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A Pioneering Experiment Combining Single-antenna and Aperture-synthesis Data to Measure Faraday Rotation with GMIMS and the CGPS by Anna Ordog, Jo-Anne C. Brown, T. L. Landecker, Alex S. Hill, Roland Kothes, Jennifer L. West, John M. Dickey, Marijke Haverkorn, Ettore Carretti, Alec J. M. Thomson, Andrea Bracco, D. A. Del Rizzo, Ryan R. Ransom, Robert I. Reid

“…While these maps show magnetic field structures on the full range of spatial scales they probe, the RM values should be interpreted with caution, as the narrow λ ^2 coverage limits sensitivity to Faraday complexity. …”
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Star photometry with all-sky cameras to retrieve aerosol optical depth at nighttime by R. Román, R. Román, D. González-Fernández, D. González-Fernández, J. C. Antuña-Sánchez, J. C. Antuña-Sánchez, C. Herrero del Barrio, C. Herrero del Barrio, S. Herrero-Anta, S. Herrero-Anta, Á. Barreto, Á. Barreto, V. E. Cachorro, V. E. Cachorro, L. Doppler, R. González, R. González, C. Ritter, C. Ritter, D. Mateos, D. Mateos, N. Kouremeti, G. Copes, A. Calle, A. Calle, M. J. Granados-Muñoz, M. J. Granados-Muñoz, C. Toledano, C. Toledano, Á. M. de Frutos, Á. M. de Frutos

“…However, the limited availability and complexity of star photometers have motivated this study to use all-sky cameras to extract starlight signals and derive AOD at night using star photometry. …”
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Strategic Spatial Segregation in Silicon Photoelectrodes: Decoupling Catalytic and Optical Functions for High‐Efficiency Solar Water Splitting by Soohyeok Park, Dongho Seo, Sangbeom Hong, Geonhwi Kim, Yejin Han, Inkyeong Park, Seongmin Lee, Min‐Joon Park, Ki Min Nam, Han‐Don Um

“…Furthermore, a scalable fabrication strategy is developed utilizing controlled wet etching and selective catalyst deposition, enabling precise realization of these complex architectures. This spatial segregation strategy presents a new direction for high‐efficiency PEC systems, offering broader implications for various solar energy conversion applications.…”
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Chlorination and oxygenation of carbon electrodes for covalent attachment of thiol-terminated molecules by Xin Zheng, Igor L. Bolotin, Beria Tanriover, Kumuditha Rathnayake, Erik J. Askins, Jordi Cabana, Neal P. Mankad, Ksenija D. Glusac

“…We further explored this reactivity in the use of benzene-1,2,4,5-tetrathiol as a bridging linker to anchor a molybdenum-based complex onto chlorinated and anodized carbon surface.…”
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LGBT Actors, Ritual and Martial Arts Groups, and State-Building in Post-Conflict Timor-Leste by Lili Chen, Laura Sjoberg

“…We see, both through our observations and through our interviewees’ eyes, more complexity in and around sex and gender roles and sexed and gendered agency than most media or even scholarly coverage of RAGs and MAGs captures. …”
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The spiritual needs and care of children and young people with life-threatening or life-shortening conditions, and parents (SPARK): a mixed-method investigation by Bryony Beresford, Natalie Richardson, Suzanne Mukherjee, Rebecca Nye, Jan Aldridge, Karl Atkin, Mark Clayton, Faith Gibson, Julia Hackett, Richard Hain, Mohammed Arshad, Paul Nash, Bob Phillips

“…Regarding capacity and competency, the research found that providing spiritual care in paediatric settings can be more complex because chaplains may be working with multiple family members at the same time. …”
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Application of weighted centroid algorithm based on weight correction in node localization of wireless sensor networks by Wengang Yu, ChunLing Yu

“…Therefore, how to improve positioning accuracy and reduce energy consumption in complex environments becomes a key challenge. To improve the positioning accuracy and extend the network application range, the study proposes a weighted centre-of-mass algorithm based on weights correction, which is optimally designed from three aspects to improve the performance. …”
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The implementation of Safety Management Systems in healthcare: a systematic review and international comparison by Zhivko Zhelev, Sian de Bell, Alison Bethel, Maria Clarke, Rob Anderson, Jo Thompson Coon

“…Topic-related factors concerned the perceived complexity of a theme and its connection with existing projects or guidelines. …”
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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…This liability coverage shifts bed allocation away from an FCFS model, but only if the policy is well-defined, clearly established, and known to providers. …”
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Explaining the Comprehensive Human-To-Human Marketig System in the Health Tourism Industry by Ali Pourang, Meysam Shirkhodaie, Mahmood Yahyazadeh far, Mohsen Alizadeh San, Masoomeh Tavangar

“…The 24 categories were validated through expert consensus, with theoretical saturation confirmed via a qualitative matrix (Table 6) and frequency analysis (Table 7), ensuring comprehensive coverage of marketing activities. 5. Conclusion The proposed H2H marketing system for health tourism offers a holistic framework to address the industry’s complexities, integrating human-centric principles, digital technologies, and service-dominant logic. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…While in most industries, at the level of retail delivery, the direct customer pays for the item received, in healthcare, the system is more complex. Deciding what metrics to base healthcare prices on has become arduous. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…While in most industries, at the level of retail delivery, the direct customer pays for the item received, in healthcare, the system is more complex. Deciding what metrics to base healthcare prices on has become arduous. …”
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