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Ketamine Infusion as an Adjunct to Opioid Analgesia in Pediatric Patients with High-Risk Neuroblastoma Undergoing Treatment with Dinutuximab: Adverse Effects and Safety in a Non-IC...
Published 2025-01-01“…Age at diagnosis ranged from 1.2 to 11.4 years. 66/187 hospitalizations included ketamine. The average daily IVMME during post-consolidation dinutuximab infusions was greater in admissions with ketamine (median 11.67 mg/day vs 6.09 mg/day; p = 0.0005). …”
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DEVELOPMENT AND CHARACTERISATION OF 3D SOLID TUMOUR CELL MODELS FOR INDIVIDUALIZED CANCER TREATMENT
Published 2021-10-01“…The colonization of a three-dimensional structure with fibroblasts enhances the biologically aggressive properties of tumor cells and demonstrates complex reciprocal interactions between the cellular elements of the tumor stroma and malignant cells, which brings the model closer to a real clinical situation.…”
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Source for the breeding of soft spring wheat in the conditions of Kirov region
Published 2021-10-01“…Sixteen samples were identified with complex resistance to dominating fungal diseases. …”
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Preliminary analysis of factors affecting economic well-being based on SDGSAT-1 nighttime light remote sensing and household survey data
Published 2025-07-01“…Since economic well-being is a multidimensional indicator involving multiple aspects of economic development level and individual residents' perception, its influencing factors are complex and lack empirical research. In order to explore the influencing factors of economic well-being, this study proposed an economic well-being factor analysis framework combining nighttime light remote sensing and household survey data. …”
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Combined genome-wide association study of facial traits in Europeans increases explained variance and improves prediction
Published 2025-07-01“…Abstract Facial appearance, one of the most recognizable and heritable human traits, exhibits substantial variation across individuals within and between populations due to its complex genetic underpinning, which remains largely elusive. …”
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Combined characterization of pore structurein deep medium-rank coal using mercury intrusion and liquid nitrogen adsorption methods and its pore fractal characteristics
Published 2025-01-01“…The results showed that: (1) Among the pore structure parameters tested with mercury intrusion method, the average pore size ranged from 31.10 to 34.70 nm, pore volume from 0.048 3 to 0.059 4 mL/g, and specific surface area from 5.590 9 to 7.652 8 m2/g. …”
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Chronic dizziness: modern treatment methods taking into account comorbidity
Published 2023-12-01“…In real-life clinical practice, PPPD and comorbid disorders are rarely diagnosed and effective treatments are rarely prescribed, so the development of modern methods for managing patients with PPPD with comorbid diseases is important.Objective: to analyze the typical management practices and evaluate the effectiveness of complex therapy in patients with PPPD and comorbid disorders.Material and methods. …”
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Linking Soil Fertility and Production Constraints with Local Knowledge and Practices for Two Different Mangrove Swamp Rice Agroecologies, Guinea-Bissau, West Africa
Published 2025-01-01“…Salinity constraints in Oio TMs limit production to an average of 110 g/m<sup>2</sup>, compared to 250 g/m<sup>2</sup> in Tombali. …”
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The Influence of Traumatic Injuries Early Diagnosis on the Development of Pulmonary Complications in Patients With Multisystem Chest Trauma
Published 2022-01-01“…With the development of purulent-inflammatory pulmonary complications, the bacteriological test of bronchoalveolar lavage was performed. Treatment included complex intensive therapy, drainage of the pleural cavity and emergency surgical interventions, if necessary.Results. …”
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UeDiff-GAN-based target detection and twin synchronization mapping for fully mechanized mining faces
Published 2025-03-01“…Current mainstream target detection methods require incorporating or modifying modules within traditional models, resulting in complex network structures and prolonged training cycles, which reduce the real-time performance of target detection. …”
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Distribution Characteristics and Ecological Risk Assessment of Heavy Metals in Typical Soil Profiles of Muchuan County, Sichuan Province
Published 2023-12-01“…Potential ecological risk index (RI) values were selected to evaluate potential ecological risks.RESULTSThe average contents of As, Cd, Cu, Hg, Ni, Pb, and Zn in the soil of YS plot were 20.8mg/kg, 0.35mg/kg, 26.38mg/kg, 0.121mg/kg, 33.29mg/kg, 42.37mg/kg, and 94.47mg/kg, respectively; The average contents of As, Cd, Cu, Hg, Ni, Pb, and Zn in the soil of PS plot were 7.21mg/kg, 0.32mg/kg, 28.32mg/kg, 0.028mg/kg, 47.34mg/kg, 33.29mg/kg, and 116.45mg/kg, respectively; The average contents of As, Cd, Cu, Hg, Ni, Pb, and Zn in the soil of GS plot were 5.42mg/kg, 0.16mg/kg, 22.38mg/kg, 0.08mg/kg, 31.8mg/kg, 30mg/kg, and 75.03mg/kg, respectively. …”
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A Tale of Side Friction Elements in Dhaka City: From Modeling Real Cases to Revealing Impacts Through Event-Based Simulation
Published 2025-01-01“…Our study reveals that the average speed of Dhaka can be reduced by up to 36.55% and the average waiting time can be increased by up to 161.3% due to side friction. …”
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Assessing the techno-economic benefits of LEMs for different grid topologies and prosumer shares
Published 2025-06-01“…The findings suggest that local energy markets can play a role in the future energy system, provided that additional infrastructure, management costs, and bureaucratic complexity are kept to a minimum.…”
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Assessment of Outcomes of the Modified Stoppa Approach in the Treatment of Acetabular Fractures: A Retrospective Cohort Study
Published 2024-11-01“…The volume of intraoperative blood loss averaged 338±254.5 ml of blood for the total sample. …”
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Abstract 157: Evaluating the Impact of Pre‐Procedural CTA on Fluoroscopy Time and Conversion Rates
Published 2023-11-01“…Introduction Cerebral angiography, essential in managing cerebrovascular disorders, exposes patients to ionizing radiation, with dose dependence on procedure complexity, patient's body habitus, and equipment used, raising safety concerns (1,2). …”
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Evaluation of the effect of DRG payment policy based on interrupted time series modeling: evidence from a tertiary hospital in Anhui Province
Published 2024-12-01“…However, challenges remain, as evidenced by decreased surgical complexity and initial drops in bed turnover rates. …”
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Using Entropy Metrics to Analyze Information Processing Within Production Systems: The Role of Organizational Constraints
Published 2025-03-01“…<i>Background</i>: The literature on measuring the complexity of production systems employs the graph and information theory. …”
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Overcoming Clusterin-Induced Chemoresistance in Cancer: A Computational Study Using a Fragment-Based Drug Discovery Approach
Published 2025-05-01“…Quantitative structure-activity relationship (QSAR) analysis revealed that the chemical size and complexity of the fragments significantly contributed to their binding affinity. …”
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Design and Electromagnetic Performance Optimization of a MEMS Miniature Outer-Rotor Permanent Magnet Motor
Published 2025-07-01“…However, with the design complexity involved in such high-performance MEMS outer-rotor motor designs, the ultra-miniature 3D coil structures and the thin-film topology surrounding the air gap have been one of the main challenges. …”
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