Concrete Dam Deformation Prediction Model Based on Attention Mechanism and Deep Learning by ZHANG Hongrui, CAO Xin, JIANG Chao, ZU Anjun, XU Mingxiang

“…Due to long-term exposure to complex and variable environmental conditions, concrete dam's structural safety faces numerous challenges. …”
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Expedited Colorectal Cancer Detection Through a Dexterous Hybrid CADx System With Enhanced Image Processing and Augmented Polyp Visualization by Akella Subrahmanya Narasimha Raju, K. Venkatesh, Ranjith Kumar Gatla, Marwa M. Eid, Aymen Flah, Zdenek Slanina, Ramy N. R. Ghaly

“…Based on the LIME explanation, this analysis found that the visualizations generated by the Kvasir dataset were more informative and even clearer when complex cases, including ulcerative colitis and polyps are concerned. …”
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Mapping recent timber harvest activity in a temperate forest using single date airborne LiDAR surveys and machine learning: lessons for conservation planning by G. Burch Fisher, Andrew J. Elmore, Matthew C. Fitzpatrick, Darin J. McNeil, Jeff W. Atkins, Jeffery L. Larkin

“…Future efforts that refine the model’s ability to better distinguish between more complex harvest classes and natural processes would be valuable.…”
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Activated/Cycling Treg Deficiency and Mitochondrial Alterations in Immunological Non-Responders to Antiretroviral Therapy by Konstantin Shmagel, Evgeniya Saidakova, Larisa Korolevskaya, Violetta Vlasova, Souheil-Antoine Younes

“…Statistical comparisons were made using the Kruskal-Wallis test with Dunn's post-hoc analysis and Mann-Whitney U-test. …”
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Comparison of virulence and resistance genes in Mannheimia haemolytica and Pasteurella multocida from dairy cattle with and without bovine respiratory disease by Adriana Garzon, Craig Miramontes, Bart C. Weimer, Rodrigo Profeta, Alejandro Hoyos-Jaramillo, Heather M. Fritz, Richard V. Pereira

“…Additionally, 28 and 15 virulence genes were identified in P. multocida and M. haemolytica, respectively. The ability of WGS-based predictions to predict phenotypic antimicrobial resistance showed variable accuracy across different antimicrobials, achieving moderate levels of agreement overall. …”
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Effects of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression in the treatment of avascular necrosis of femoral he... by Lei Sun, Ziyao Xu, Zhongyuan Zhang, Jinwei Zhao, Mengshuai Sun, Guangling Gao, Fang Gao, Hongjiang Jiang, Changjun Ju

“…Abstract Background Avascular necrosis of femoral head (ANFH) is a localized destruction of the femoral head caused by a variety of complex reasons, which eventually progresses to collapse of the femoral head and loss of joint function. …”
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Back pain exercise therapy remodels human epigenetic profiles in buccal and human peripheral blood mononuclear cells: an exploratory study in young male participants by Claire Burny, Mia Potočnjak, Mia Potočnjak, Annika Hestermann, Sophie Gartemann, Michael Hollmann, Frank Schifferdecker-Hoch, Nina Markanovic, Simone Di Sanzo, Simone Di Sanzo, Michael Günsel, Victor Solis-Mezarino, Moritz Voelker-Albert, Moritz Voelker-Albert

“…Our findings reflect the complex interplay of an individual's background and lifestyle upon therapeutic exposure. …”
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Protective Effects of Frankincense Oil on Wound Healing: Downregulating Caspase-3 Expression to Facilitate the Transition from the Inflammatory to Proliferative Phase by Krishnaraju Venkatesan, Durgaramani Sivadasan, Moufida Abderrahmen Al Weslati, Mohammed Gayasuddin Mouid, Manoj Goyal, Monika Bansal, Mohamed EL-Dosoky Mohamed Salama, Syed Azizullah Ghori, Fazil Ahmad

“…<b>Background/Objectives:</b> Wound healing is a complex process involving inflammation, oxidative stress, immune modulation, and tissue regeneration. …”
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Child and caregiver perspectives on implementing a transdiagnostic cognitive behavioral therapy for children impacted by trauma in a residential care setting by David Lindenbach, Emily Y. Wang, Jennifer Scammell, Tania O’Neill, Sydnee Bennett, Farhat Mohammadi, Jill Ehrenreich-May, Paul D. Arnold, Gina Dimitropoulos

“…Methods: Qualitative interviews were conducted with children (age 10–12; n = 6) and caregivers (age 32–55; n = 12). Reflexive thematic analysis was used to organize feedback into codes, and themes were inductively generated. …”
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Are we ready to integrate modern technologies into the medical curriculum for students a systematic review by Seyedeh Toktam Masoumian Hosseini, Karim Qayumi, Ata Pourabbasi, Elnaz Haghighi, Babak Sabet, Alireza Koohpaei, Zahra Shafiei, Mohsen Masoumian Hosseini, Parniya Nemati

“…Abstract Background This study aims to explore the diverse applications of contemporary technological innovations in education and to propose effective strategies for their integration into the curriculum, addressing the complexities and collaborative efforts required for meaningful learning experiences. …”
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Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations by Ayat Kadhi, Ayat Kadhi, Ayat Kadhi, Edward Eid, Michel J. Massaad, Inaam El-Rassy, Dana Maria Khoury, Yutaka Shimomura, Nelly Rubeiz, Mazen Kurban, Mazen Kurban, Mazen Kurban, Georges Nemer, Georges Nemer

“…This was evident from the presence of IL17RA in the patient’s peripheral blood mononuclear cells (PBMCs) and the ability of the mutant IL17RA to dimerize with both wild-type protein and its partners IL17RC and IL17RD. …”
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Development and validation of AI-based automatic segmentation and measurement of thymus on chest CT scans by Yusheng Guo, Bingxin Gong, Guowei Jiang, Wang Du, Shuangfeng Dai, Qi Wan, Dongyong Zhu, Chanyuan Liu, Yi Li, Qing Sun, Qianqian Fan, Bo Liang, Lian Yang, Chuansheng Zheng

“…Abstract Background Due to the complex anatomical structure and dynamic involution process of the thymus, segmentation and evaluation of the thymus in medical imaging present significant challenges. …”
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Agroclimatic and agroecotoxicological justification of zonal chemical protection systems against harmful organisms for field crops under conditions of climate change in Ukraine by O. Borzykh, L. Bublyk, V. Chaika, L. Gavrylyuk, I. Kruk, O. Shevchuk, T. Neverovska, O. Bakhmut

“…With the help of the Arc GIS — Arc INFO software complex, the agroclimatic and agroecotoxicological zoning of the territory of Ukraine under conditions of climatic changes of 2010—2020 was carried out. …”
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ANTIMICROBIAL ACTIVITY OF WATER-ETHANOLIC EXTRACTIONS FROM QUERCUS ROBUR L. LEAVES AND BUDS by N. A. Ryabov, V. M. Ryzhov, V. A. Kurkin, S. D. Kolpakova, A. V. Zhestkov, A. V. Lyamin

“…There are interesting plant objects that have an antimicrobial action due to the content of a complex of biologically active substances in them. …”
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The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer by Si Chen, Caihong Yao, Na Tian, Chunying Zhang, Yuemei Chen, Xuting Wang, Yue Jiang, Tonghao Zhang, Tingting Zeng, Yali Song

“…This interference impairs the body's ability to eliminate these microorganisms promptly, allowing them to persist by evading immune defenses. …”
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CD200R1 immune checkpoint blockade by the first-in-human anti-CD200R1 antibody 23ME-00610: molecular mechanism and engineering of a surrogate antibody by Cristina Melero, S. Jimmy Budiardjo, Anahita Daruwalla, Lance Larrabee, Oleg Ganichkin, Alexander J. Heiler, Jill Fenaux, Ben Chung, Germaine Fuh, Yao-Ming Huang

“…We used phage display libraries of 23ME–00610 variants with individual CDR residues randomized to all 20 amino acids, from which we identified mutations that switched on MfCD200R1 binding. Structural analysis suggests how the surrogate, named 23ME–00611, acquires the ortholog binding ability at the equivalent epitope of 23ME–00610. …”
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Impact of 2D versus 3D fibroblast models on Leishmania species invasion in vitro: Rab5 dynamics and actin activity in initial infection by Rebecca Thereza Silva Santa Brígida, Rebecca Thereza Silva Santa Brígida, Adeniele Lopes da Cruz Carneiro, Adeniele Lopes da Cruz Carneiro, Felipe Tuji de Castro Franco, Brenda Furtado Costa, Brenda Furtado Costa, Ana Paula Drummond Rodrigues

“…In a bidimensional environment, its interaction with the extracellular matrix and manipulation of endocytic processes reveal a complex ability to alter cellular entry mechanisms. …”
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Enhancing environmental decontamination and sustainable production through synergistic and complementary interactions of actinobacteria and fungi by Juliana M. Saez, Enzo E. Raimondo, Stefanie B. Costa-Gutierrez, Juan D. Aparicio, Domenica Mosca Angelucci, Enrica Donati, Marta A. Polti, Maria C. Tomei, Claudia S. Benimeli

“…Although challenges still exist, their potential to address complex problems has been demonstrated and deserves further investigation.…”
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Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. by He Li, Tove Ragna Reksten, John A Ice, Jennifer A Kelly, Indra Adrianto, Astrid Rasmussen, Shaofeng Wang, Bo He, Kiely M Grundahl, Stuart B Glenn, Corinne Miceli-Richard, Simon Bowman, Sue Lester, Per Eriksson, Maija-Leena Eloranta, Johan G Brun, Lasse G Gøransson, Erna Harboe, Joel M Guthridge, Kenneth M Kaufman, Marika Kvarnström, Deborah S Cunninghame Graham, Ketan Patel, Adam J Adler, A Darise Farris, Michael T Brennan, James Chodosh, Rajaram Gopalakrishnan, Michael H Weisman, Swamy Venuturupalli, Daniel J Wallace, Kimberly S Hefner, Glen D Houston, Andrew J W Huang, Pamela J Hughes, David M Lewis, Lida Radfar, Evan S Vista, Contessa E Edgar, Michael D Rohrer, Donald U Stone, Timothy J Vyse, John B Harley, Patrick M Gaffney, Judith A James, Sean Turner, Ilias Alevizos, Juan-Manuel Anaya, Nelson L Rhodus, Barbara M Segal, Courtney G Montgomery, R Hal Scofield, Susan Kovats, Xavier Mariette, Lars Rönnblom, Torsten Witte, Maureen Rischmueller, Marie Wahren-Herlenius, Roald Omdal, Roland Jonsson, Wan-Fai Ng, for UK Primary Sjögren's Syndrome Registry, Gunnel Nordmark, Christopher J Lessard, Kathy L Sivils

“…Our results establish OAS1 as a risk locus for SS and support a potential role for defective viral clearance due to altered IFN response as a genetic pathophysiological basis of this complex autoimmune disease.…”
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Unsupervised Feature Selection via a Dual-Graph Autoencoder with <inline-formula><math display="inline"><semantics><mrow><msub><mi mathvariant="bold-script">l</mi><mrow><mn mathvar... by Zhichao Song, Meiling Chen, Liang Xie, Xi Fang

“…While such data contain abundant information, they are often accompanied by substantial noise, high redundancy, and complex intrinsic structures, posing significant challenges for analysis and modeling. …”
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