Community pharmacists' decision-making patterns in clinical prescription checking: A simulation-based study by Ali Elgebli, Jason Hall, Denham L. Phipps

“…Background: Community pharmacists (CPs) make a significant number of decisions on the clinical appropriateness of prescriptions daily to ensure safe and effective use of medications, in a process known as “clinical checking”. The process is complex and is affected by multiple factors in practice. …”
Get full text

Translation, validation and extended factor models of the German State Difficulties in Emotion Regulation Scale (S-DERS) by M. Sicorello, M. Elsaesser, D. R. Kolar

“…The extended factor models highlight the multidimensional nature of emotion regulation difficulties, with complex interrelations among distinct but related constructs. …”
Get full text

Influenza in pregnant women: a clinical case by G. E. Ryzhov, A. N. Turapova, Zh. B. Ponezheva, V. B. Romeyko

“…In the article, the authors noted that early detection of influenza and the appointment of adequate complex therapy helps to reduce the frequency of occurrence and manifestation of complications. …”
Get full text

Family life under strain: the impact of forced migration on refugee parenting in reception centers by Jennifer Drummond Johansen, Sverre Varvin, Mette Sagbakken

“…This exacerbated their mental health issues and impaired their ability to provide a secure and nurturing environment for their children. …”
Get full text

Multichannel convolutional transformer for detecting mental disorders using electroancephalogrpahy records by Mamadou Dia, Ghazaleh Khodabandelou, Syed Muhammad Anwar, Alice Othmani

“…Recently, deep learning techniques have gained prominence for their ability to analyze complex datasets, such as electroencephalography recordings. …”
Get full text

Developing nursing approaches across the chronic illness trajectory: a grounded theory study of care from diagnosis to end-of-life in Western Amhara, Ethiopia by Abebe Dilie Afenigus, Mastewal Ayehu Sinshaw

“…Data was collected via in-depth interviews. Data analysis followed a constant comparative method, involving open, axial, and selective coding to identify key strategies and challenges across the illness trajectory.ResultsThe primary finding of this study emphasizes the evolving and adaptive role of nurses in chronic illness management, highlighting their ability to provide personalized care, emotional support, and education throughout the illness trajectory. …”
Get full text

Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm. by Xiao-yong Li, Stewart MacArthur, Richard Bourgon, David Nix, Daniel A Pollard, Venky N Iyer, Aaron Hechmer, Lisa Simirenko, Mark Stapleton, Cris L Luengo Hendriks, Hou Cheng Chu, Nobuo Ogawa, William Inwood, Victor Sementchenko, Amy Beaton, Richard Weiszmann, Susan E Celniker, David W Knowles, Tom Gingeras, Terence P Speed, Michael B Eisen, Mark D Biggin

“…Surprisingly, for five of the six factors, their recognition sites are not unambiguously more constrained evolutionarily than the immediate flanking DNA, even in more highly bound and presumably functional regions, indicating that comparative DNA sequence analysis is limited in its ability to identify functional transcription factor targets.…”
Get full text

CLINICAL AND EXPERIMENTAL ARGUMENTATION OF MODIFIED METHOD FOR PERI-IMPLANT BONE REDUCTION EVALUATION DURING VARIOUS SCHEMES OF PROSTHETIC REHABILITATION by A.T. Kenyuk

“…The obtained data allow to individualize the approach of assessing the quality of complex iatrogenic interventions conducted with the ability to analyze the impact of various factors on peri-implant bone changes, including the adequacy of choosing specific schemes of prosthetic rehabilitation of dental patients supported by implants structures. …”
Get full text

Spatiotemporal Evolution of Precipitation Concentration in the Yangtze River Basin (1960–2019): Associations with Extreme Heavy Precipitation and Validation Using GPM IMERG by Tao Jin, Yuliang Zhou, Ping Zhou, Ziling Zheng, Rongxing Zhou, Yanqi Wei, Yuliang Zhang, Juliang Jin

“…However, its long-term trends, associations with atmospheric teleconnections as potential drivers, and links to extreme heavy precipitation events remain poorly understood in complex basins like the Yangtze River Basin. This study analyzes these aspects using ground station data from 1960 to 2019 and conducts a comparison using the Global Precipitation Measurement Integrated Multi-satellitE Retrievals for GPM (GPM IMERG) satellite product. …”
Get full text

Lightweight highland barley detection based on improved YOLOv5 by Minghui Cai, Hui Deng, Jianwei Cai, Weipeng Guo, Zhipeng Hu, Dongzheng Yu, Houxi Zhang

“…We chose depthwise separable convolution (DSConv) and ghost convolution (GhostConv) for the backbone and neck networks, respectively, to reduce the parameter and computational complexity. In addition, the integration of convolutional block attention module (CBAM) enhances the model’s ability to focus on target object in complex backgrounds. …”
Get full text

A Novel MPE-LPP-ELM Recognition Method for the Fault Diagnosis of Spiral Bevel Gears by Jiang Lingli, Tan Hongchuang, Li Xuejun, Yang Dalian

“…In previous studies, multiscale permutation entropy (MPE) has been proven to be an effective nonlinear analysis tool for complexity and irregularity evaluations of complex mechanical systems. …”
Get full text

Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients. by Anwaar Ahmad, Jacqueline H Enzlin, Nikhil R Bhagwat, Nils Wijgers, Anja Raams, Esther Appledoorn, Arjan F Theil, Jan H J Hoeijmakers, Wim Vermeulen, Nicolaas G J Jaspers, Orlando D Schärer, Laura J Niedernhofer

“…Recombinant XPF harboring either mutation was purified in a complex with ERCC1 and tested for its ability to incise a stem-loop structure in vitro. …”
Get full text

Comparative effectiveness of root canal machining with modern ni-ti tools by L. Yu. Orekhova, V. Yu. Vashneva, T. V. Porkhun, Yu. A. Zaitseva

“…Despite their great diversity, there is no universal system that is simple and effective, allowing you to work in the root canal with complex anatomy. Therefore, new tools are being created.Aim. …”
Get full text

Evaluation of performance and matrix compatibility of mixed mode C18-SCX SPME fibers for compounds with different physicochemical properties by Marcos Tascon, Ezel Boyaci, Nathaly Reyes-Garcés, Janusz Pawliszyn

“…Absolute matrix effects were negligible (93–111 %), underscoring the fibers’ ability to deliver clean extracts for LC-MS analysis. …”
Get full text

ScaleViM-PDD: Multi-Scale EfficientViM with Physical Decoupling and Dual-Domain Fusion for Remote Sensing Image Dehazing by Hao Zhou, Yalun Wang, Wanting Peng, Xin Guan, Tao Tao

“…Remote sensing images are often degraded by atmospheric haze, which not only reduces image quality but also complicates information extraction, particularly in high-level visual analysis tasks such as object detection and scene classification. …”
Get full text

The role of cholecalciferol deficiency in the development of dermatoses in geriatric patients by Anna V. Urakova, Yuri N. Perlamutrov, Dina E. Klyuchnikova

“…The aim of the study was to evaluate the role of cholecalciferol deficiency in the development of dermatological pathology and effectiveness its order in complex therapy in geriatric patients. Materials and methods. …”
Get full text

Predicting the Compression Index of Clayey Soils Using a Hybrid Genetic Programming and XGBoost Model by Abolfazl Baghbani, Katayoon Kiany, Hossam Abuel-Naga, Yi Lu

“…This hybrid approach has the potential to advance geotechnical engineering practices by providing accurate and interpretable models for diverse soil profiles and complex site conditions.…”
Get full text

Hybrid virtual screening and molecular dynamics approach for identification of allosteric modulator of EAAT2 by Chennu Manisha, Nagarjuna Palathoti, Jagdish Chand, Akey Krishna Swaroop, Jubie Selvaraj, B.R. Prashantha Kumar, Prisil Naveentha X, Brindha Durairaj, Antony Justin

“…Subsequently, molecular dynamics simulations confirmed the stability of the complex and its binding ability to the allosteric pocket of EAAT2. …”
Get full text

Development and Validation of a Simple and Cost-Effective LC-MS/MS Method for the Quantitation of the Gut-Derived Metabolite Trimethylamine N-Oxide in Human Plasma of Healthy and H... by Nikolaos A. Parisis, Panoraia Bousdouni, Aikaterini Kandyliari, Maria-Helen Spyridaki, Amalia Despoina Koutsogianni, Christina Telli, Konstantinos K. Tsilidis, Antonios E. Koutelidakis, Andreas G. Tzakos

“…LC-MS/MS has emerged as a powerful tool for the determination of TMAO due to its high sensitivity, specificity, and ability to handle complex matrices. Herein, we describe the development and validation of an LC-MS/MS method for the determination of TMAO in human blood plasma. …”
Get full text

Digital and socioeconomic inequalities in perceived mobility restrictions for activity participation: Captive users in Madrid by Segundo Paico-Saavedra, Alberto Rojas-Rivero, Raúl F. Elizondo-Candanedo, Aldo Arranz-López, Julio A. Soria-Lara

“…A survey of captive public transport users was conducted, and Principal Component Analysis (PCA) was used to identify key dimensions of vulnerability. …”
Get full text