Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…Our findings provide the first demonstration that TXA efficiently inhibits MSC-driven plasmin generation by competitively blocking plasminogen binding to the uPA•uPAR complex at the cell plasma membrane.DiscussionWe propose that plasmin formation on MSCs may be involved in pathological processes such as endometrial hemorrhage (metrorrhagia and Post-Partum Hemorrhage), autoimmune and ischaemic diseases, as well as cancer. …”
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Organising general practice for care homes: a multi-method study by Barbara Hanratty, Rachel Stocker, David Sinclair, Katie Brittain, Karen Spilsbury, Daniel Stow, Louise Robinson, Fiona E Matthews

“…Different structures (e.g. scheduled visits) provide opportunities to develop effective, efficient care, but flounder without established, trusting relationships. …”
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Variation within and between digital pathology and light microscopy for the diagnosis of histopathology slides: blinded crossover comparison study by David RJ Snead, Ayesha S Azam, Jenny Thirlwall, Peter Kimani, Louise Hiller, Adam Bickers, Clinton Boyd, David Boyle, David Clark, Ian Ellis, Kishore Gopalakrishnan, Mohammad Ilyas, Paul Kelly, Maurice Loughrey, Desley Neil, Emad Rakha, Ian SD Roberts, Shatrughan Sah, Maria Soares, YeeWah Tsang, Manuel Salto-Tellez, Helen Higgins, Donna Howe, Abigail Takyi, Yan Chen, Agnieszka Ignatowicz, Jason Madan, Henry Nwankwo, George Partridge, Janet Dunn

“…Analysis showed the differences detected occurred in entities known to produce differences in interpretation between pathologists. …”
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Surfactant-mediated transport behavior of zinc oxide nanoparticles in porous media by Yujue Wang, Zhou Cheng, Ming Wu, Yanru Hao

“…Nanomaterials and surfactants are widely detected in soil-groundwater environments, while the surfactant-mediated transport behavior of nanoparticles has not been sufficiently investigated. …”
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Wind Turbine Static Errors Related to Yaw, Pitch or Anemometer Apparatus: Guidelines for the Diagnosis and Related Performance Assessment by Davide Astolfi, Silvia Iuliano, Antony Vasile, Marco Pasetti, Salvatore Dello Iacono, Alfredo Vaccaro

“…The optimization of the efficiency of wind turbine systems is a fundamental task, from the perspective of a growing share of electricity produced from wind. …”
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Combating a Global Threat to a Clonal Crop: Banana Black Sigatoka Pathogen Pseudocercospora fijiensis (Synonym Mycosphaerella fijiensis) Genomes Reveal Clues for Disease Control. by Rafael E Arango Isaza, Caucasella Diaz-Trujillo, Braham Dhillon, Andrea Aerts, Jean Carlier, Charles F Crane, Tristan V de Jong, Ineke de Vries, Robert Dietrich, Andrew D Farmer, Claudia Fortes Fereira, Suzana Garcia, Mauricio Guzman, Richard C Hamelin, Erika A Lindquist, Rahim Mehrabi, Olman Quiros, Jeremy Schmutz, Harris Shapiro, Elizabeth Reynolds, Gabriel Scalliet, Manoel Souza, Ioannis Stergiopoulos, Theo A J Van der Lee, Pierre J G M De Wit, Marie-Françoise Zapater, Lute-Harm Zwiers, Igor V Grigoriev, Stephen B Goodwin, Gert H J Kema

“…Melting-curve assays suggest that the genomes of two closely related members of the Sigatoka disease complex, P. eumusae and P. musae, also are expanded. …”
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Achievements and prospects of applying high-throughput sequencing techniques to potato genetics and breeding by I. V. Bykova, N. A. Shmakov, D. A. Afonnikov, A. V. Kochetov, E. K. Khlestkina

“…Special attention is given to peculiarities of the models and the approaches used in potato genetic studies, taking into account the complex organization of its genome and a high level of heterozygosity. …”
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Proteomic mechanism of sugar and organic acid metabolism during Korla fragrant pear (Pyrus sinkiangensis Yü) fruit development by Yi Wang, Yonghui Deng, Wei Jiang, Shijie An, Ling Ma, Zhendong Wang, Qiangqing Zheng, Pan Yan, Qiling Chen

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AI-assisted anatomical structure recognition and segmentation via mamba-transformer architecture in abdominal ultrasound images by Shih-Fang Chang, Shih-Fang Chang, Po-Yi Wu, Ming-Chang Tsai, Ming-Chang Tsai, Vincent S. Tseng, Chi-Chih Wang, Chi-Chih Wang

“…Combining Mamba and transformer architectures, this hybrid design was well-suited for the timely analysis of complex anatomical structures segmentation in abdominal ultrasonography, where accuracy and efficiency are critical in clinical practice.ConclusionThe proposed mamba-transformer hybrid recognition framework simultaneously detects and segments multiple abdominal organs and lesions in ultrasound images, achieving superior segmentation accuracy, visualization effect, and inference efficiency, thereby facilitating improved medical image interpretation and near real-time diagnostic sonography that meets clinical needs.…”
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Exploring Gene Expression and Alternative Splicing in Duck Embryonic Myoblasts via Full-Length Transcriptome Sequencing by Jintao Wu, Shuibing Liu, Dongcheng Jiang, Ya’nan Zhou, Hongxia Jiang, Xiaoyun Xiao, Boqian Zha, Yukai Fang, Jie Huang, Xiaolong Hu, Huirong Mao, Sanfeng Liu, Biao Chen

“…This extensive transcriptomic investigation not only sheds light on the intricate molecular mechanisms driving skeletal muscle development in ducks but also provides significant insights for future breeding strategies aimed at enhancing the efficiency of duck production. The results emphasize the efficacy of ONT sequencing in uncovering complex regulatory networks within avian species, ultimately contributing to progress in animal husbandry.…”
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Thermal Analysis of Outer Rotor BLDC Motor for Drone Considering Airflow Ventilation Cooling by Jaebeom Kang, Jiheon Lee, Hyeong-Jin Kim, Thanh-Tuan Nguyen, Jiyoung Lee, Yi-Hwa Song, Sung-Joo Yoo

“…Considering these operating conditions, thermal analysis that accurately reflects the airflow characteristics around the motor is essential in the motor design process. …”
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Water scarcity in semi-arid California compromises perennial alfalfa’s high yield and carbon sinking potentials by Tianxin Wang, Kanishka Mallick, Joseph Verfaille, Daphne Szutu, Dennis Baldocchi

“…From our analysis, the lower evaporative fraction and higher sensible heat flux in 2022 indicated potential water stress, which was further reflected in a decrease water use efficiency and a lower canopy omega coefficient (i.e., higher stomatal closure). …”
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Canopy Chlorophyll Content Inversion of Mountainous Heterogeneous Grasslands Based on the Synergy of Ground Hyperspectral and Sentinel-2 Data: A New Vegetation Index Approach by Yi Zheng, Yao Wang, Tayir Aziz, Ali Mamtimin, Yang Li, Yan Liu

“…The results indicated the following: (1) DRECAVI demonstrated the highest accuracy in CCC retrieval for mountainous vegetation (R² = 0.74, RMSE = 16.79, MAE = 12.50) compared to other VIs and hybrid methods, effectively mitigating saturation effects in high biomass areas and capturing a weak bimodal distribution pattern of CCC in the montane meadow. (2) The blue band B1 enhances atmospheric correction robustness by suppressing aerosol scattering, and the red-edge band B7 overcomes the sensitivity limitations of conventional red-edge indices (such as NDVI705, CIred-edge, and NDRE), demonstrating the potential application of the synergy mechanism between the blue band and the red-edge band. (3) Although the S2BP achieved high accuracy (R² = 0.73, RMSE = 19.83, MAE = 14.71) without saturation effects and detected a bimodal distribution of CCC in the montane meadow of the study area, its algorithmic complexity hindered large-scale operational applications. …”
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Leveraging artificial intelligence for photo identification to aid CITES enforcement in combating illegal trade of the endangered humphead wrasse (Cheilinus undulatus) by C. Y. Hau, W. K. Ngan, Y. Sadovy de Mitcheson, Y. Sadovy de Mitcheson, Y. Sadovy de Mitcheson

“…To address this, a photo identification system utilizing the unique complex facial patterns of humphead wrasse was established enabling enforcement officers to detect possible laundering by monitoring individual fish at retail outlets.Methods and resultsDeep learning models were developed for facial pattern extraction and comparison to enhance efficiency and accuracy. …”
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Jet Interaction with Galaxy Cluster Mergers by P. Domínguez-Fernández, J. ZuHone, R. Weinberger, E. Bellomi, L. Hernquist, P. Nulsen, G. Brunetti

“…Recent radio observations reveal the complex morphologies of cluster diffuse emission, potentially linked to interactions between AGN bursts and the cluster environment. …”
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AIPerf: Automated Machine Learning as an AI-HPC Benchmark by Zhixiang Ren, Yongheng Liu, Tianhui Shi, Lei Xie, Yue Zhou, Jidong Zhai, Youhui Zhang, Yunquan Zhang, Wenguang Chen

“…The plethora of complex Artificial Intelligence (AI) algorithms and available High-Performance Computing (HPC) power stimulates the expeditious development of AI components with heterogeneous designs. …”
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Determination of Trace Rare Earth Elements in Tungsten-Molybdenum Ore by Inductively Coupled Plasma-Mass Spectrometry with Microwave Digestion System by Junfei CAO, Ting WANG, Jian LI, Ying LI

“…Relative standard deviation (RSD) of method precision was lower than 2.0%, the method detection limit was 0.0002-0.0087µg/g, and the spiked recovery of real samples was between 80.0% and 114.0%. …”
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Synthetic Data Generation and Evaluation Techniques for Classifiers in Data Starved Medical Applications by Wan D. Bae, Shayma Alkobaisi, Matthew Horak, Siddheshwari Bankar, Sartaj Bhuvaji, Sungroul Kim, Choon-Sik Park

“…With their ability to find solutions among complex relationships of variables, machine learning (ML) techniques are becoming more applicable to various fields, including health risk prediction. …”
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Law enforcement in context of transformation of the labor sphere and modernization of the theory of labor relations by S. Yu. Chucha

“…It proves the need to release the employee from liability for offenses detected by artificial intelligence. It is proposed to continue research on the prospects for the formation of labor procedural law.…”
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Marker-assisted selection in the development of advanced apple-tree forms and donors combining scab resistance with increased fruit storability by I. I. Suprun, E. A. Egorov, A. I. Nasonov, E. V. Lobodina, S. V. Tokmakov, I. V. Stepanov

“…They can also be used for breeding purposes as complex donors.…”
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