Novel Epigenetics Control (EpC) Nanocarrier for Cancer Therapy Through Dual-Targeting Approach to DNA Methyltransferase and Ten-Eleven Translocation Enzymes by Risa Mitsuhashi, Kiyoshi Sato, Hiroyoshi Kawakami

“…The formation of core–shell nanoparticles and complexation with pDNA were investigated and optimized by dynamic light scattering, zeta potential measurement, and agarose gel electrophoresis. …”
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Improving the Principles of Identifying Critical Requirements for the Assembly of High-Precision Products by A. V. Nazaryev, P. Yu. Bochkarev

“…The application of this technique makes it possible to increase the reliability of the source information obtained during the implementation of an enlarged block of design procedures, as well as the validity and efficiency of identifying rational manufacturing technologies at subsequent stages of the system implementation, while providing the specified quality, accuracy of products, and reducing the complexity and cost of their manufacture.…”
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Comparative Physicochemical and Pharmacotechnical Evaluation of Three Topical Gel-Cream Formulations by Ramona Pârvănescu, Cristina Trandafirescu, Adina Magdalena Musuc, Emma Adriana Ozon, Daniela C. Culita, Raul-Augustin Mitran, Cristina-Ionela Stănciulescu, Codruța Șoica

“…In the context of modern dermocosmetic development, multifunctional topical gel-cream formulations must be efficient for both therapeutic efficacy and cosmetic applications. …”
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Comparative Results of Emergency Carotid Endarterectomy and Emergency Carotid Angioplasty With Stenting in the Acute Period of Ischemic Stroke. Multicenter Study Results by A. N. Kazantsev, V. A. Porkhanov, G. G. Khubulava, R. A. Vinogradov, V. N. Kravchuk, M. A. Chernyavsky, E. Y. Kachesov, A. A. Erofeyev, V. V. Matusevich, K. P. Chernykh, N. E. Zarkua, G. S. Bagdavadze, R. Y. Lider, M. S. Bayandin, A. V. Khudetskaya, A. P. Chernykh, A. G. Baryshev, A. R. Shabayev, V. A. Lutsenko, R. V. Sultanov, D. V. Fattakhov, A. V. Kutsenko, L. V. Timchenko, A. E. Chikin, E. Y. Kalinin, S. V. Artyukhov, T. E. Zaitseva, Y. P. Linets

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Project quality, regulation quality by Elena Mussinelli

“…Hence, it is worth reflecting on the effectiveness and efficiency of a regulatory framework that has been governing territorial, urban and building transformations in an increasingly articulated and specialised manner with a view to improving the quality and sustainability of natural and anthropic habitats. …”
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A comprehensive suite for extracting neuron signals across multiple sessions in one-photon calcium imaging by Pablo Vergara, Yuteng Wang, Sakthivel Srinivasan, Zhe Dong, Yu Feng, Iyo Koyanagi, Deependra Kumar, Yoan Chérasse, Toshie Naoi, Yuki Sugaya, Takeshi Sakurai, Masanobu Kano, Tristan Shuman, Denise Cai, Masashi Yanagisawa, Masanori Sakaguchi

“…CaliAli performs computationally efficient signal extraction from concatenated video sessions that enhances the detectability of weak calcium signals. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…Volume-based reimbursement schemes prioritize efficiency, regardless of these major bioethical principles. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…Volume-based reimbursement schemes prioritize efficiency, regardless of these major bioethical principles. …”
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Optimizing CNN-Based Diagnosis of Knee Osteoarthritis: Enhancing Model Accuracy with CleanLab Relabeling by Thomures Momenpour, Arafat Abu Mallouh

“…The substantial enhancement in model performance is primarily attributed to Cleanlab’s robust ability to detect and correct mislabeled instances, thereby improving the overall quality and reliability of the training data and enabling the model to better learn and capture complex radiographic patterns associated with KOA. …”
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Comprehensive thermal properties, kinetic, and thermodynamic analyses of biomass wastes pyrolysis via TGA and Coats-Redfern methodologies by Ocident Bongomin, Charles Nzila, Josphat Igadwa Mwasiagi, Obadiah Maube

“…The results identified three distinct pyrolysis stages: drying, devolatilization, and char formation, with macadamia nutshell demonstrating the highest thermal reactivity and efficient devolatilization characteristics, reflected by its lowest initial devolatilization temperature (175 °C) and highest peak temperature (380 °C). …”
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Real‐Climatic Microcontroller‐in‐the‐Loop (RCMIL) Framework: A Novel, Rapid, and Cost‐Effective Approach for Verifying Photovoltaic Control Systems by Ambe Harrison, Idriss Dagal, Wulfran Fendzi Mbasso, Fritz Nguemo Kemdoum, Reagan Jean Jacques Molu, Hamid Belghiti, Pradeep Jangir

“…Furthermore, the MIL feature allows the system to work on commercial microcontrollers, which reflects the real‐world problems that control algorithms would encounter in actual deployment circumstances. …”
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On the Issue of Practical Orientation of Teaching Students of Technical Universities the Basics of Descriptive Geometry by L. G. Polyakov, T. D. Polyakova

“…One of the ways to improve the efficiency of learning disciplines is to link theory with practice. …”
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The role of intersectionality in shaping participant engagement with health research through digital methods: findings from a qualitative study by Cherish Boxall, Felicity L. Bishop, Nisreen A. Alwan, Shaun Treweek, Gareth Griffiths, Nnenna Ekeke, John McGavin, Jane Thorp, Katherine Bradbury

“…The third theme uncovered the complex ways participants established trust in research, relying on multi-channel trust makers. …”
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Age-related differences in eye blink-related neural activity and functional connectivity during driving by Emad Alyan, Stefan Arnau, Stephan Getzmann, Julian Elias Reiser, Melanie Karthaus, Edmund Wascher

“…Driving is a complex task that requires effective neural processing and coordination, which degrade with aging. …”
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A Dual-Source Deep Learning Model for Mapping Wet Anabranches in Braided Rivers on the Tibetan Plateau by Xiaolu Liu, Xiaoyi Ma, Shuai Qin, Tang Liu, Chenghu Zhou

“…Dynamically monitoring these rivers is crucial for understanding the unique sedimentary processes and hydrodynamic patterns of the plateau. However, the complex network of water channels and sandbars, coupled with frequent cloud cover, intricate terrain, and numerous branches in the plateau region, poses significant challenges to traditional monitoring and extraction methods. …”
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Review of online quality control for laser directed energy deposition (LDED) additive manufacturing by Long Ye, Hao Xue, Zhaosheng Li, Yichang Zhou, Guangyu Chen, Fangda Xu, Ruslan Melentiev, Stephen Newman, Nan Yu

“…Laser directed energy deposition (LDED) is an emerging branch of metal-based additive manufacturing (AM) processes, offering unprecedented capabilities for high-performance fabrication with complex geometries and near-net shapes. This technology is gathering increasing attention from industries such as biomedical, automotive, and aerospace. …”
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Prediction of regional water resources carrying capacity based on stochastic simulation: A case study of Beijing-Tianjin-Hebei Urban Agglomeration by Wentao Xu, Junliang Jin, Jianyun Zhang, Shanshui Yuan, Ming Tang, Yanli Liu, Tiesheng Guan

“…Study region: Beijing-Tianjin-Hebei urban agglomeration in China Study focus: The prediction of water resources carrying capacity (WRCC) can provide an effective reference for the rational allocation and efficient utilization of water resources. Traditional prediction methods obtained a definite WRCC value but fail to reflect the uncertainty of WRCC changes and limit reference for the optimal allocation of water resources. …”
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Research on High-Accuracy, Lightweight, Superfast Model for Nitrogen Diagnosis and Plant Growth in Lettuce (<i>Lactuca sativa</i> L.) by Xuyang Li, Iftikhar Hussain Shah, Xiaohao Gong, Muhammad Azam, Wu Jinhui, Pengli Li, Yidong Zhang, Qingliang Niu, Liying Chang

“…Nondestructive techniques have the ability to handle complex relationships in the data, enabling more accurate and efficient nitrogen diagnosis. …”
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Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…Our findings provide the first demonstration that TXA efficiently inhibits MSC-driven plasmin generation by competitively blocking plasminogen binding to the uPA•uPAR complex at the cell plasma membrane.DiscussionWe propose that plasmin formation on MSCs may be involved in pathological processes such as endometrial hemorrhage (metrorrhagia and Post-Partum Hemorrhage), autoimmune and ischaemic diseases, as well as cancer. …”
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Cellulose/TiO₂ Humidity Sensor by Susana Devesa, Zohra Benzarti, Madalena Costa, Diogo Cavaleiro, Pedro Faia, Sandra Carvalho

“…Resistivity-type humidity sensors, which detect changes in electrical resistance in response to variations in environmental humidity, have garnered significant interest due to their widespread application in industry, agriculture, and daily life. …”
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