Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches by Elahe Asadollahi, Alireza Zomorodipour, Zahra-Soheila Soheili, Babak Jahangiri, Majid Sadeghizadeh

“…The immunoglobulin kappa (Igκ) chain signal peptide was incorporated to improve secretion efficiency. The stability of the final MNEV construct in complex with TLR3, TLR4, and TLR9 was confirmed through binding analysis and refinement of the best-predicted 3D model. …”
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Progress in phase field research of dead lithium in lithium batteries by Jing LIU, Huiyi CHEN, Huiyu LIU, Shu LI

“…These problems considerably reduce the Coulomb efficiency and service life of lithium metal batteries and constitute a substantial obstacle to the development and wide application of lithium metal batteries. …”
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Determination of Sequential Well Placements Using a Multi-Modal Convolutional Neural Network Integrated with Evolutionary Optimization by Seoyoon Kwon, Minsoo Ji, Min Kim, Juliana Y. Leung, Baehyun Min

“…In geoenergy science and engineering, well placement optimization is the process of determining optimal well locations and configurations to maximize economic value while considering geological, engineering, economic, and environmental constraints. This complex multi-million-dollar problem involves optimizing multiple parameters using computationally intensive reservoir simulations, often employing advanced algorithms such as optimization algorithms and machine/deep learning techniques to find near-optimal solutions efficiently while accounting for uncertainties and risks. …”
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Back pain exercise therapy remodels human epigenetic profiles in buccal and human peripheral blood mononuclear cells: an exploratory study in young male participants by Claire Burny, Mia Potočnjak, Mia Potočnjak, Annika Hestermann, Sophie Gartemann, Michael Hollmann, Frank Schifferdecker-Hoch, Nina Markanovic, Simone Di Sanzo, Simone Di Sanzo, Michael Günsel, Victor Solis-Mezarino, Moritz Voelker-Albert, Moritz Voelker-Albert

“…We also performed an exploratory analysis to confirm the usability of molecular profiles in (1) mapping lifestyle choices and (2) evaluating the distance of a given participant to an optimal health state.ConclusionThis pre-post cohort study highlights the potential of integrated molecular profiles to score therapy efficiency. Our findings reflect the complex interplay of an individual's background and lifestyle upon therapeutic exposure. …”
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On the Hydrodynamic and Structural Performance of Thermoplastic Composite Ship Propellers Produced by Additive Manufacturing Method by Erkin Altunsaray, Serkan Turkmen, Ayberk Sözen, Alperen Doğru, Pengfei Liu, Akile Neşe Halilbeşe, Gökdeniz Neşer

“…The material extrusion technique, one of the additive manufacturing methods, is becoming more widespread day by day, especially in the production of objects with complex forms. This prevalence has not yet been reflected in the marine industry. …”
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TheraVision: Engineering platform technology for the development of oncolytic viruses based on herpes simplex virus type 1 by Christina Funk, Nadja Uhlig, Zsolt Ruzsics, Florentin Baur, Matthias Peindl, Sarah Nietzer, Karina Epting, Gabriele Vacun, Gudrun Dandekar, Catherine Botteron, Christian Werno, Thomas Grunwald, Susanne M. Bailer

“…Viruses are able to efficiently penetrate cells, multiply, and eventually kill infected cells, release tumor antigens, and activate the immune system. …”
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Correlations of pilot trainees' brainwave dynamics with subjective performance evaluations: insights from EEG microstate analysis by Mengting Zhao, Andrew Law, Chang Su, Sion Jennings, Alain Bourgon, Wenjun Jia, Marie-Hélène Larose, David Bowness, Yong Zeng

“…ObjectiveThis study aims to investigate the relationship between the subjective performance evaluations on pilot trainees' aircraft control abilities and their brainwave dynamics reflected in the results from EEG microstate analysis. …”
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Challenging assumptions: a tripartite assessment of medical quality, resource utilization, and equity concerns in pediatric telemedicine by Motti Haimi, Ruslan Sergienko, Tzipi Hornik-Lurie, Dov Albukrek

“…These associations may reflect complex interactions between patient characteristics, provider behavior, and care modalities that warrant further investigation. …”
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THE ROLE OF PLASMA ENRICHED WITH PLATELETS AND GROWTH FACTORS IN MODERN MEDICAL PRACTICE by O.V. Pavlenko, R.Yu. Bida

“…Growth factors play an important role in coordinating all processes of healing. This article reflects the relevant aspects of the application in medicine modern biological technology autoplazmy enriched with platelets. in recent years, marked a significant increase in interest for this biomaterial that caused high efficiency at a high level of safety and low cost. …”
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Understanding the acute care context to inform palliative care improvements: a qualitative study of hospital-based multidisciplinary clinicians by Claudia Virdun, Gursharan K. Singh, Patsy Yates, Jane L. Phillips, Alison Mudge

“…The analysis generated six themes, reflecting the challenges of providing optimal palliative care within acute hospital wards: 1. …”
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Multi-analytical assessment of shale gas potential in the West Bokaro Basin, India: A clean energy prospect by Manish Kumar Srivastava, Kaushal Kishor, Alok K. Singh, Alok Kumar, Khairul Azlan Mustapha, Amit Saxena

“…The West Bokaro Basin, part of the Damodar Valley, is known for its rich coal deposits and complex geological history. The basin's stratigraphy includes significant coal-bearing formations interbedded with shales, which may be potential sources of shale gas. …”
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Performance optimization of static mixer in urea-SCR system considering flow and turbulence characteristics by Chanho Jung, Sanghyeon Lee, Jaehwan Jang, Sangkyung Na, Gyungmin Choi, Minsung Choi, Yeseul Park

“…The urea-Selective Catalytic Reduction (SCR) system is known to be the most proven technology among the various de-NOx technologies in diesel engines. …”
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Classifying and Localizing Abnormalities in Brain MRI Using Channel Attention Based Semi-Bayesian Ensemble Voting Mechanism and Convolutional Auto-Encoder by Syed Muhammad Ahmed Hassan Shah, Asad Ullah, Jawaid Iqbal, Sami Bourouis, Syed Sajid Ullah, Saddam Hussain, Muhammad Qasim Khan, Yaser Ali Shah, Ghulam Mustafa

“…The classification of brain tumors into multiple classes is recognized as a complex challenge within the field of medical imaging. …”
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Enhancing Sustainable Manufacturing in Industry 4.0: A Zero-Defect Approach Leveraging Effective Dynamic Quality Factors by Rouhollah Khakpour, Ahmad Ebrahimi, Seyed Mohammad Seyed Hosseini

“…Moreover, the gathered data from defect detection can be used in two ways: to prevent defect occurrence in the future (detect-prevent) and to design algorithms for predicting when a defect may occur in the future, hence, to prevent defects before they arise (predict-prevent). …”
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Wind-induced transmission line interruption fragility models: An adaptive GAN-augmented probabilistic classification approach for extremely unbalanced data by Mazin Al-Mahrouqi, Abdollah Shafieezadeh, Jieun Hur, Jae-Wook Jung, Jeong-Gon Ha, Daegi Hahm

“…Additionally, we develop an advanced active learning framework that efficiently selects the most relevant instances from large, imbalanced datasets for model training. …”
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Accelerated carbonate weathering by immobilized recombinant carbonic anhydrase by Io Antonopoulou, Ayanne de Oliveira Maciel, Marikagiusy Di Giacomo, Maria Elena Russo, Ulrika Rova, Paul Christakopoulos, Piero Salatino, Antonio Marzocchella

“…CA immobilization could offer a mitigation strategy for the non-selective adsorption of the free enzyme on lime mud particles during the CO2 capturing reaction. …”
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Kinetics of the reactions of OH with CO, NO, and NO₂ and of HO₂ with NO₂ in air at 1 atm pressure, room temperature, and tropospheric water... by M. Rolletter, A. Hofzumahaus, A. Novelli, A. Wahner, H. Fuchs, H. Fuchs

“…In this work, rate coefficients were measured with a high accuracy (<span class="inline-formula">&lt;5</span> %) at 1 <span class="inline-formula">atm</span> pressure, at room temperature, and in humidified air using laser flash photolysis and detection of the radical decay by laser-induced fluorescence. …”
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Evaluating N₂O emissions and carbon sequestration in temperate croplands with cover crops: insights from field trials by V. Nasser, R. Dechow, M. Helfrich, A. Meijide, P. S. Rummel, P. S. Rummel, H.-J. Koch, R. Ruser, L. Essich, K. Dittert

“…Yet, their influence on nitrous oxide (<span class="inline-formula">N₂O</span>) emissions – a potent greenhouse gas – presents a complex challenge, with findings varying across different studies. …”
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Characterization of emerging H3N3 avian influenza viruses in poultry in China by Cheng Yan, Jianzhong Shi, Pengfei Cui, Yuan Chen, Congcong Wang, Yan Wang, Jiahao Miao, Yaping Zhang, Huihui Kong, Xianying Zeng, Guobin Tian, Chengjun Li, Yasuo Suzuki, Guohua Deng, Hualan Chen

“…Seventeen viruses were tested in mice and most replicated efficiently but were not lethal. Six viruses were tested in guinea pigs, and four of them transmitted efficiently via respiratory droplets. …”
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ULTRASOUND CRITERIA OF EARLY DIAGNOSTICS OF OVARIAN CARCINOMA by L. A. Ashrafyan, N. A. Babaeva, I. B. Antonova, S. V. Ivashina, A. V. Lyustik, O. I. Aleshikova, E. V. Gerfanova, А. А. Dobrenko

“…Therefore modern ultrasonography can detect and differentiate rather efficiently the localized variants of OC, provided that the main part of diagnosis is formed in mode of color and power Doppler mapping, which shall be taken into consideration during the primary diagnostics of OC.…”
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