Developing a congenital hyperinsulinism prioritized research agenda: a patient-driven international collaborative research network by Tai L. S. Pasquini, Indraneel Banerjee, Henrik Thybo Christesen, Louise S. Conwell, Antonia Dastamani, Diva D. De Leon, Sarah E. Flanagan, David Gillis, Jennifer M. Kalish, Katherine Lord, Mahlet Mesfin, Jennifer Schmitt, Senthil Senniappan, Charles A. Stanley, Paul S. Thornton, David Zangen, Julie Raskin, the Congenital Hyperinsulinism Collaborative Research Network Members

“…CRN members worked across 7 workstream groups through a structured process to brainstorm gaps and corresponding solutions to formalize the HI PRA.Actionable recommendationsA total of 362 gaps were identified across research, infrastructure, knowledge, and funding. …”
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Barriers and drivers to COVID-19 protective behaviours of forcibly displaced myanmar nationals (FDMN)/ rohingya refugees in Cox's bazar, Bangladesh: A scoping review by Sarah Reda, Zarah Yusuf, Basel Karo, Balwinder Singh Chawla, Andreas Jansen, Saskia Lange, Jorge Martinez, Emily Dorothee Meyer, Julia Neufeind, Aarti Shrikrishana Singh, Elisa Wulkotte, Cath Jackson

“…This review identified complex and inter-related barriers and drivers to COVID-19 protective behaviors in Cox's Bazar, and many interventions to address these. …”
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Estimating Dengue Outbreak Thresholds in West Africa: A Comprehensive Analysis of Climatic Influences in Burkina Faso, 2018–2024 by John Otokoye Otshudiema, Watton R. Diao, Sonia Marie Wend-Kuuni Ouedraogo, Alain Ngoy Kapete, Laurent Moyenga, Emmanuel Chanda, Tieble Traore, Otim Patrick Ramadan, Alimuddin Zumla

“…Additionally, intermediate precipitation levels showed a complex relationship with higher incidence rates. …”
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Factors associated with self-care in people with advanced chronic kidney disease and their experience of care in Catalonia: an application of Leventhal’s self-regulatory model by Elena Pintado-Outumuro, Betlem Salvador-González, Victoria Morín-Fraile, Llúcia Benito-Aracil, Oriol Cunillera-Puertolas, Teresa Marblava Buades-Sabater, Esther Salillas-Adot, Rosa M Sánchez-Cabrera, Esther López-Gonzalo, Iris Lumillo-Gutiérrez

“…Abstract Background Although evidence has demonstrated the influence of perceptions of chronic kidney disease on health outcomes in patients, there are still gaps in our knowledge regarding how such perceptions manifest themselves in specific populations with advanced chronic kidney disease (ACKD). …”
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Spatiotemporal water quality data reconstruction: A tensor factorization framework by Xuke Wu, Kun Shan, Lan Wang, Jingkai Wang, Mingsheng Shang

“…While traditional imputation methods fail to adequately capture complex spatiotemporal dependencies among water quality variables, this study proposes a novel nonnegative tensor factorization (NTF) model designed to reconstruct missing values by effectively modeling variable-site-time triad interactions. …”
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Application of dynamic systems modeling approach to rank optimal urban waste management strategies using SWOT method by Hamid Shahbandarzadeh, Mohammad Hossein Kabgani

“…Environmental issues are also at the top of all human problems.Originality/Value:  In this research, an attempt has been made to examine innovation from three aspects: theoretical, technical and practical gaps, which can be mentioned as the strengths of the current research compared to other research. …”
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The impact of polypharmacy on adherence to pharmacotherapy for coronary heart disease with comorbid conditions: insights from the EUROASPIRE V observational study in Ukraine by M. M. Dolzhenko, N. A. Bilousova, L. I. Yakovenko, V. A. Nesukai, N. A. Kozhuharyova

“…To determine the prevalence of polypharmacy and identify gaps in the rational use of drugs in patients with CHD and comorbid conditions, and to assess the subsequent impact on treatment adherence in the Ukrainian cohort of the EUROASPIRE V study. …”
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Analysis of the spatiotemporal evolution and driving factors of land use change in Jinan springs area of the Northern Karst region, China from 1986 to 2022 by Shenting Gang, Xiaoyun Kong, Tao Jia, Minghui Lv, Lixia Li

“…PCA identified population growth, economic development, and precipitation variability as the main drivers of land-use changes, highlighting the complex interplay of human activities and climatic factors. …”
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Evaluation of Neural, Systemic and Extracerebral Activations During Active Walking Tasks in Older Adults Using fNIRS by Meltem Izzetoglu, Roee Holtzer

“…This study design allowed us to address critical gaps in the extant literature concerning fNIRS-derived brain activations during active walking. …”
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Speech-language therapy and occupational therapy for patients with mild cognitive impairment and dementia: a retrospective cohort study using German health claims data by Fiona Dörr, Daniela Holle, Bashar Morouj, Dominik Obermüller, Sascha Sommer, Markus Wübbeler, Kerstin Bilda

“…Abstract Background Dementia is a complex, multifactorial syndrome characterised by cognitive decline and impaired daily functioning, representing a major risk factor for long-term care dependency. …”
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Unmet needs in the management of hereditary angioedema from the perspective of Brazilian patients by Pedro Giavina-Bianchi, MD, PhD, Mara Giavina-Bianchi, MD, PhD, Raquel de Oliveira Martins, Maria Cristina Fortunato, PharmD, Ana Claudia Guersoni, MD, PhD

“…Understanding the perspectives of patients is crucial for identifying unmet needs in managing this complex condition. Objective: This study aimed to gather real-world insights from Brazilian patients with C1 inhibitor deficiency HAE to identify their unmet needs and assess their perceptions of the effectiveness of current care in preventing and treating HAE attacks. …”
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PRACTICAL TRAINING OF OFFICERS OF THE STATE FIRE SERVICE THROUGH GAME-BASED LEARNING by V. V. Bulgakov, A. A. Lazarev, E. P. Konovalenko, T. A. Mochalova

“…However, in a technologically developed society, there is a contradiction between the increased requirements to young officers’ competencies and the impossibility to achieve a proper complex of graduates’ characteristics by providing education through only standard traditional techniques, which continue to be prevalent in higher education and ensure optimisation of professional activity in general.The aim of the present publication was to present the developed methodology of game-based learning for training of cadets of educational organisations of higher education of the EMERCOM of Russia. …”
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Oral Health Maintenance and Barriers among Patients Attending Psychiatry Ward of Tertiary Hospital of Bhubaneswar: A Qualitative Research by Payal Dash, Gunjan Kumar, Pranab Mahapatra

“…Psychiatric patients frequently experience a complex interplay of factors contributing to compromised oral health. …”
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Hybrid LSTM–Transformer Architecture with Multi-Scale Feature Fusion for High-Accuracy Gold Futures Price Forecasting by Yali Zhao, Yingying Guo, Xuecheng Wang

“…Traditional forecasting models face significant limitations in capturing long-term trends, addressing abrupt volatility, and mitigating multi-source noise within complex market environments characterized by nonlinear interactions and extreme events. …”
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Single Test‐Based Diagnosis and Subtyping of Pulmonary Hypertension Caused by Fibrosing Mediastinitis Using Plasma Metabolic Analysis by Yating Zhao, Chunmeng Ding, Hongling Su, Aqian Wang, Aiping Tang, Hongfan Zhao, Ya Ma, Min Zhang, Wanshan Liu, Ruimin Wang, Ziyue Zhang, Shouzhi Yang, Dingyitai Liang, Yida Huang, Kun Qian, Lin Huang, Qihua Fu, Yunshan Cao

“…By addressing existing gaps in diagnostic strategies, this research highlights the potential of metabolic analysis in elucidating the metabolic landscape of PH.…”
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Dynamic monitoring of fine-grained ecological vulnerability in dryland urban agglomeration integrating novel remote sensing index and explainable machine learning by Chunqiang Li, Shanchuan Guo, Qin Huang, Haowei Mu, Bo Yuan, Zilong Xia, Hong Fang, Wei Zhang, Pengfei Tang, Peijun Du

“…However, persistent technological gaps in large-scale, fine-grained and long-term monitoring hinder a comprehensive understanding of vulnerability patterns in these fragile regions. …”
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Residents’ Perceptions of Impending Forced Relocation in Urban China by Xin Li

“…In chapter 3, we discuss a complex interplay between different stakeholders, by focusing the implementation of SRPs and the changing roles of different stakeholders. …”
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2024 VCP International Conference: Exploring multi-disciplinary approaches from basic science of valosin containing protein, an AAA+ ATPase protein, to the therapeutic advancement... by A. Peck, A. Dadi, Z. Yavarow, L.N. Alfano, D. Anderson, M.R. Arkin, T.F. Chou, E.S. D'Ambrosio, J. Diaz-Manera, J.P. Dudley, A.G. Elder, N. Ghoshal, C.E. Hart, M.M. Hart, D.M. Huryn, A.E. Johnson, K.B. Jones, V. Kimonis, E. Kiskinis, E.B. Lee, T.E. Lloyd, M. Mapstone, A. Martin, H. Meyer, T. Mozaffar, C.U. Onyike, G. Pfeffer, A. Pindon, M. Raman, I. Richard, D.C. Rubinsztein, M. Schiava, A.K. Schütz, P.S. Shen, D.R. Southworth, A.M. Staffaroni, M. Taralio-Gravovac, C.C. Weihl, Q. Yao, Y. Ye, N. Peck

“…Tsui-Fen Chou, the meeting aimed to center the patient as a research partner, harmonize diverse stakeholder engagement, and bridge the gap between basic and clinical neuroscience as it relates to VCP-MSP. …”
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Parvalbumin interneurons in the hippocampal formation of individuals with Alzheimer’s disease: a neuropathological study of abnormal phosphorylated tau in neurons by Paula Merino-Serrais, Paula Merino-Serrais, Paula Merino-Serrais, Sergio Plaza-Alonso, Sergio Plaza-Alonso, Sergio Plaza-Alonso, Silvia Tapia-Gonzalez, Gonzalo León-Espinosa, Gonzalo León-Espinosa, Javier DeFelipe, Javier DeFelipe, Javier DeFelipe

“…However, elucidating how these pathological hallmarks ultimately contribute to cognitive deficits remains a complex challenge. While AD is commonly conceptualized as a disorder characterized by synaptic failure, substantial knowledge gaps persist regarding the mechanisms underlying the onset and progression of the disease, underscoring the need for novel and more effective therapeutic approaches. …”
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Graphical representation of global water models by H. Müller Schmied, H. Müller Schmied, S. N. Gosling, M. Garnsworthy, L. Müller, C.-E. Telteu, A. K. Ahmed, L. S. Andersen, J. Boulange, P. Burek, J. Chang, H. Chen, L. Gudmundsson, M. Grillakis, L. Guillaumot, N. Hanasaki, A. Koutroulis, R. Kumar, G. Leng, J. Liu, J. Liu, J. Liu, X. Liu, I. Menke, I. Menke, V. Mishra, V. Mishra, Y. Pokhrel, O. Rakovec, O. Rakovec, L. Samaniego, L. Samaniego, Y. Satoh, H. L. Shah, M. Smilovic, T. Stacke, E. Sutanudjaja, W. Thiery, A. Tsilimigkras, Y. Wada, N. Wanders, T. Yokohata

“…<p>Numerical models are simplified representations of the real world at a finite level of complexity. Global water models are used to simulate the terrestrial part of the global water cycle, and their outputs contribute to the evaluation of important natural and societal issues, including water availability, flood risk, and ecological functioning. …”
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