Comprehensive computational analysis via Adverse Outcome Pathways and Aggregate Exposure Pathways in exploring synergistic effects from radon and tobacco smoke on lung cancer by Thomas Jaylet, Vinita Chauhan, Laura Mezquita, Nadia Boroumand, Olivier Laurent, Karine Elihn, Lovisa Lundholm, Olivier Armant, Karine Audouze

“…This approach also identified gaps in understanding joint exposure, particularly the lack of mechanistic studies on the precise role of certain KEs such as inflammation, as well as the need for studies that more closely replicate real-world exposure conditions. …”
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Barriers and facilitators to housing and healthcare services for people experiencing homelessness with concurrent brain injury, mental health and substance use disorders: a qualita... by Grace C. Warren, Cole J. Kennedy, Cole J. Kennedy, Cole J. Kennedy, Nicholas Gavas, Julia Schmidt, Julia Schmidt, Erica Woodin, Erica Woodin, Janelle Breese Biagioni, Mauricio A. Garcia-Barrera, Mauricio A. Garcia-Barrera

“…Manifest content analysis revealed five barriers and five facilitators: Barriers included (1) Stigma, (2) Insufficient Investment, (3) Siloed Systems, (4) Generalized Approaches to Housing, and (5) Policies that do not Support Complex Needs, while facilitators included (1) Increasing Discourse on the Intersections of ABI, MHSU, and Homelessness, (2) Government Commitment to Systemic Change, (3) Collaboration Across Organizations, (4) Community-Based Services, and (5) Supportive Housing Models.ConclusionsThese findings highlight gaps in existing policies and services while identifying effective approaches to supporting individuals experiencing these intersections. …”
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Urban morphology impacts on urban microclimate using artificial intelligence – a review by Ahmed Marey, Jiwei Zou, Sherif Goubran, Liangzhu Leon Wang, Abhishek Gaur

“…By leveraging urban morphology indicators such as sky view factor, building density, and green space ratio, AI models can analyze complex interactions across various spatiotemporal scales. …”
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Deep-Learning-Based Land Cover Mapping in Franciacorta Wine Growing Area by Girma Tariku, Isabella Ghiglieno, Andres Sanchez Morchio, Luca Facciano, Celine Birolleau, Anna Simonetto, Ivan Serina, Gianni Gilioli

“…This study addresses these gaps by presenting a methodology for semantic segmentation of land covers in agricultural areas using satellite images and deep learning models with pre-trained backbones. …”
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Provider readiness and implementation barriers for lung cancer screening in a safety-net system by Maria C. Mejia, Yu-Heng Hilary Ma, Lisa M. Lowenstein, Kiara K. Spooner, Gabrielle Duhon, Elisa E. Douglas, Viola Leal, Robert J. Volk

“…Objective: Lung cancer screening (LCS) with low-dose computed tomography is a critical preventive strategy, yet implementation remains complex, particularly in safety-net settings. This study assessed provider knowledge, attitudes, and readiness to implement LCS, including shared decision-making (SDM) and smoking cessation, within a large urban safety-net healthcare system. …”
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A comprehensive review of the pathogenic mechanisms of Pseudomonas aeruginosa: synergistic effects of virulence factors, quorum sensing, and biofilm formation by Xindan Zhang, Xindan Zhang, Duo Zhang, Duo Zhang, Di Zhou, Di Zhou, Shuai Zheng, Shuai Zheng, Shuang Li, Qinlong Hou, Qinlong Hou, Gen Li, Gen Li, Huiming Han, Huiming Han

“…Over the past decade, extensive research has elucidated its complex virulence repertoire, including exotoxins, proteases, and siderophores; the hierarchical Quorum Sensing (QS) networks; and its robust capacity for biofilm formation. …”
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A Review of Soil Constitutive Models for Simulating Dynamic Soil–Structure Interaction Processes Under Impact Loading by Tewodros Y. Yosef, Chen Fang, Ronald K. Faller, Seunghee Kim, Qusai A. Alomari, Mojtaba Atash Bahar, Gnyarienn Selva Kumar

“…This paper addresses existing gaps in the literature by offering a structured basis for selecting and evaluating constitutive models in simulations of high-energy vehicular impact events involving soil–structure systems. …”
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Fracture Risk in Chronic Kidney Disease: Addressing an Overlooked Complication by Guido Gembillo, Concetto Sessa, Walter Morale, Luca Zanoli, Antonino Catalano, Salvatore Silipigni, Luca Soraci, Andrea Corsonello, Maria Princiotto, Carlo Lomonte, Domenico Santoro

“…The overlap between CKD-Mineral and Bone Disorder (CKD-MBD) and osteoporosis leads to complex bone changes that increase the likelihood of fragility fractures. …”
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The impact of natural drivers and human activities on sediment flux in Hekouzhen-Longmen section of China over the last 100 years by Sinuo Fan, Xiaohui Jiang, Yuxin Lei, Xiang Su, Yuehong Li

“…To fill these research gaps, this study has collated the hydrological and meteorological data over the past century. …”
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Underwater SLAM Meets Deep Learning: Challenges, Multi-Sensor Integration, and Future Directions by Mohamed Heshmat, Lyes Saad Saoud, Muayad Abujabal, Atif Sultan, Mahmoud Elmezain, Lakmal Seneviratne, Irfan Hussain

“…Autonomous underwater vehicles (AUVs) rely on simultaneous localization and mapping (SLAM) for real-time navigation and mapping in these complex environments. However, traditional SLAM techniques face significant obstacles, including poor visibility, dynamic lighting conditions, sensor noise, and water-induced distortions, all of which degrade the accuracy and robustness of underwater navigation systems. …”
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Close-to-nature silviculture in eastern Quebec: Advances over the last decade by Robert Schneider, Laurie Dupont-Leduc, Vincent Gauthray-Guyénet, Nicolas Cattaneo, LaraMelo, Tommy Simard, Alexis Begni, Raphel Turquin, Anabelle Morache-Mercier, Samuel Pinna, Ulysse Rémillard, Charles Nock

“…Nevertheless, other close-to-nature silvicultural practices must be developed, as gaps between managed and unmanaged stands persist. …”
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Small extracellular vesicles: messengers at the service of breast cancer agenda in the primary and distant microenvironments by Angela Galardi, Valentina Fogazzi, Claudia Tottone, Marta Giussani, Serenella M. Pupa, Giulia Cosentino, Marilena V. Iorio

“…Abstract Breast cancer (BC) remains a leading cause of cancer-related mortality in women, with complex mechanisms driving its initiation, progression, and resistance to therapy. …”
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5G Networks Security Mitigation Model: An ANN-ISM Hybrid Approach by Rafiq Ahmad Khan, Habib Ullah Khan, Hathal Salamah Alwageed, Hussein Al Hashimi, Ismail Keshta

“…The advent of Fifth-Generation (5G) networks has introduced significant security challenges due to increased complexity and diverse use cases. Conventional threat models may fall short of addressing these emerging threats effectively. …”
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A national perspective: integrating medical humanities to address burnout and stress in Chinese medical education by Huiwen Zhai, Jiaolong Xue, Haotan Wu, Shuang Liao, Christopher Lavender, Yangludan Lv, Wanfei Xie, Di Wang, Yu Cheng

“…Conclusion This study illuminated the complex relationship between medical education, burnout, stress, and students' perception of medical humanities issues. …”
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Person-environment fit of formal and informal caregivers for older adults: a scoping review by Yuting Huang, Vivian Weiqun Lou, Wenling Zhang, Gehao Yang, Xiaobo Ke, Fan Yang, Haochu Li, Junyao Zheng, Yiyan Zhou, Wenjie Li, Shihan Lu

“…Abstract Background Caring for older adults is a dynamic and complex process, and analyzing personal and environmental factors separately fails to capture its full nature. …”
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QIP approach to improving quality of diagnosis and initial management of heart failure for inpatients on general internal medicine wards by Mazin Alhussein, Raunak Singh

“…Heart failure (HF) is a complex clinical syndrome that is associated with high levels of morbidity and mortality, and reduced quality of life.1 In 2014, the overall HF prevalence in the UK was 920,616 cases, accounting for 1.6% of the UK population.2 Accurate medical documentation is crucial for assessing adherence to national standards for HF diagnosis and management, as well as for capturing clinical indicators measured in the National Heart Failure Audit (NHFA), which are linked to improved patient outcomes.3 In this audit, we aimed to evaluate the completeness and accuracy of key performance indicators (KPIs) for HF documentation in general internal medicine (GIM) at Leicester Royal Infirmary (LRI).This prospective audit collected data over ∼1 month from inpatients diagnosed with HF on GIM wards at LRI. …”
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Characterization and simulation of conglomerate reservoirs using core data of Triassic Baikouquan Formation, Mahu Depression by Xiangyang Li, Fengxia Li, Zhiwen Huang, Hancheng Ji, Haibo Wang, Liang Chen, Zhonghao Zhang, Xukai Shi

“…This approach is expected to be valuable for similar complex conglomerate reservoirs worldwide.…”
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Implementation of a Quality Improvement and Clinical Decision Support Tool for Cancer Diagnosis in Primary Care: Process Evaluation by Sophie Chima, Barbara Hunter, Javiera Martinez-Gutierrez, Natalie Lumsden, Craig Nelson, Dougie Boyle, Kaleswari Somasundaram, Jo-Anne Manski-Nankervis, Jon Emery

“…The Medical Research Council’s Framework for Developing and Evaluating Complex Interventions was used to analyze and interpret the data. …”
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Development and Validation of a Predictive Model for Activities of Daily Living Dysfunction in Older Adults: Retrospective Analysis of Data From the China Health and Retirement Lon... by Fangbo Lin, Chao Liu, Hua Liu

“…ADL dysfunction encompasses both basic ADL (BADL) and instrumental ADL (IADL), which assess fundamental self-care and complex environmental interactions, respectively. …”
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Innovative, Technology-Driven, Digital Tools for Managing Pediatric Urinary Incontinence: Scoping Review by Lola Bladt, Jiri Vermeulen, Alexandra Vermandel, Gunter De Win, Lukas Van Campenhout

“…However, this review also identified gaps in research, highlighting the need for more rigorous research to better assess the tools’ effectiveness and address the complex, multifaceted challenges of pediatric urinary incontinence management. …”
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