Health-related preferences of older patients with multimorbidity: the protocol for an evidence map by Marjan Van Den Akker, Odette Wegwarth, Joerg J Meerpohl, Sharon E Straus, Tammy Hoffmann, Ferdinand M Gerlach, Christine Schmucker, Ana Isabel González-González, Christiane Muth

“…Introduction Interaction of conditions and treatments, complicated care needs and substantial treatment burden make patient–physician encounters involving multimorbid older patients highly complex. To optimally integrate patients’ preferences, define and prioritise realistic treatment goals and individualise care, a patient-centred approach is recommended. …”
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Fusing multiplatform topo-bathymetric point clouds based on a pseudo-grid model: A case study around Ganquan Island, South China sea by Fanlin Yang, Xiaolin Yu, Xiankun Wang, Xiaozheng Mai, Chunxiao Wang, Anxiu Yang, Dianpeng Su

“…High-quality, full-coverage topographic bathymetric data is crucial for marine economic development and ecological environment protection. Due to the complex environment of land-sea transition zone, it is challenging to acquire comprehensive bathymetric topography using a single sensor. …”
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Adaptive evolution and functional significance of the PPARGC1A gene across diverse animal species by Seyed Mahdi Hosseini, Farman Ullah, Muhammad Zulfiqar Ahmad, Majid Pasandideh, Aixin Liang, Guohua Hua, Liguo Yang

“…Employing maximum likelihood assessments through MEGA, we scrutinized 447 codon positions addressing the entire coding region, excluding positions mired by gaps or missing data. Distinct codons manifested variance in selection pressures, particularly codons 4, 11, 66, and 123, which exhibited positive dN‐dS values suggestive of positive selection. …”
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Harnessing nanotechnology for stem-cell therapies: revolutionizing neurodegenerative disorder treatments – a state-of-the-art update by Neevashini Chengebroyen, Anmol Seelan, Kamal Yoonus Thajudeen, Saad Ali Alshehri, Aritra Biswas, Israrahmed Adur, Vino Sundararajan, Sajitha Lulu Sudhakaran, Harpreet Singh

“…By integrating existing knowledge and highlighting critical gaps, this review seeks to foster continued research and interdisciplinary collaboration, accelerating progress in this rapidly evolving field.…”
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A Robust Framework for Bamboo Forest AGB Estimation by Integrating Geostatistical Prediction and Ensemble Learning by Lianjin Fu, Qingtai Shu, Cuifen Xia, Zeyu Li, Hailing He, Zhengying Li, Shaoyang Ma, Chaoguan Qin, Rong Wei, Qin Xiang, Xiao Zhang, Yiran Zhang, Huashi Cai

“…Accurate above-ground biomass (AGB) quantification is confounded by signal saturation and data fusion challenges, particularly in structurally complex ecosystems like bamboo forests. To address these gaps, this study developed a two-stage framework to map the AGB of <i>Dendrocalamus giganteus</i> in a subtropical mountain environment. …”
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Performance of Mushrooms in Fermented Beverages: A Narrative Review by Tiziana Di Renzo, Anna Reale, Stefania Nazzaro, Pasquale Marena, Muhamad Hafiz Abd Rahim, Nurul Aqilah Mohd Zaini, Nur ‘Aliah Daud, Wan Abd Al Qadr Imad Wan-Mohtar

“…Microbial activity breaks down complex compounds in mushrooms, making their bioactive components more accessible for absorption; bringing unique flavors, aromas, and textures; and creating a rich-sensory experience while offering potential health benefits. …”
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A critical review of soil pollution sources and advances in the remediation of arsenic-contaminated soil by Fei He, Fukang Liu, Shehong Li, Xiaomin Mu, Qiao Han, Lian Song, Jen-How Huang

“…Furthermore, it delineated the research gaps that require addressing in subsequent studies. …”
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HalalChain: A decentralized blockchain model for enhanced data integrity, real-time compliance, and automated verification in halal food supply chain by Muhammad Muntasir Yakubu, Mohd Fadzil B Hassan, Kamaluddeen Usman Danyaro, Bello Musa Yakubu, Abdullah Abdulrahman Alabdulatif, S. Zulaikha Beevi, Aliyu Garba

“…This paper introduces HalalChain, a blockchain-based model designed to address these gaps through decentralized verification, automated compliance, and tamper-proof data integrity. …”
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Glucagon-like peptide 1 receptor agonists and cancer risk: advancing precision medicine through mechanistic understanding and clinical evidence by Anqi Lin, Yanxi Ding, Zhengrui Li, Aimin Jiang, Zaoqu Liu, Hank Z. H. Wong, Quan Cheng, Jian Zhang, Peng Luo

“…The potential biological mechanisms underlying their influence on cancer risk are complex, involving metabolic regulation, direct antitumor effects, immune modulation, and epigenetic changes. …”
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Using RE-AIM to inform the adaptation of a clinical decision support application for hypertension disorders of pregnancy: a qualitative study of provider perspectives by Shannon Marie Canfield, Yarrow Stanley, Parijat Ghosh, Amy Braddock, Randi Foraker

“…However, challenges like integrating tools into complex workflows, overcoming usability barriers, and addressing resource disparities must be prioritized. …”
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Area-based development of ecologically sensitive urban areas: systematic literature review to understand prevailing concepts and practices by Deeksha Chhachhiya, Ashwani Kumar, Satish Pipralia

“…Urban environmental security in these areas acquires an added layer of complexity, as the fragility of the surrounding ecosystems directly influences the vulnerability of urban systems. …”
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Decision support systems for waste-to-energy technologies: A systematic literature review of methods and future directions for sustainable implementation in Ghana by Theophilus Frimpong Adu, Lena Dzifa Mensah, Mizpah Ama Dziedzorm Rockson, Francis Kemausuor

“…The study also highlights significant gaps in the current application of DSS to WtE technologies, particularly in the context of developing nations like Ghana. …”
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Urban digital twins for citizen-centric planning: A systematic review of built environment perception and public participation by Junjie Luo, Pengyuan Liu, Xinya Kong, Junru Shen, Qiaoqiao Wu, Da Xu

“…Results indicate a rapid increase in UDT research post-2020, particularly in North America, Europe, and Asia, led by the United States, China, and Germany. However, significant gaps remain, notably the underrepresentation of rural and peri-urban contexts, highlighting geographic and contextual biases. …”
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Current Insights into Nutritional Management of Phenylketonuria: An Update for Children and Adolescents by Dana-Teodora Anton-Păduraru, Felicia Trofin, Adina Chis, Lucia Maria Sur, Violeta Streangă, Dana Elena Mîndru, Olivia Simona Dorneanu, Diana Păduraru, Eduard Vasile Nastase, Romana Vulturar

“…The current literature underscores the essential role of diet in both managing PKU and preventing obesity, but malnutrition in these children is a complex issue that necessitates a multifaceted approach. …”
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Exploring medicine classification and accessibility: a qualitative study by Awangku Khairi Wazien Pengiran Umar, Hui Poh Goh, Zaidah Rizidah Murang, Andi Hermansyah, Inayat Ur Rehman, Khang Wen Goh, Kwan Foong Chee, Long Chiau Ming

“…Background Brunei Darussalam’s medicine control governance landscape is complex, driven by legislative directives and directed by the Brunei Darussalam Medicines Control Authority (BDMCA). …”
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Evaluation of ecological environment quality in China's mining areas by remote sensing: A review by LI Feiyue, LI Jun, XIAO Wu, ZHANG Chengye, WANG Shanshan, YANG Junquan, ZHANG Xiaoping, CHENG Yang

“…This study attempts to review existing practices of ecological environmental quality evaluation in mining areas using remote sensing in terms of 1) requirements for ecological environmental quality evaluation in mining areas in relevant national laws, regulations and standards, 2) research progress in ecological environmental quality evaluation in mining areas based on remote sensing, 3) existing research gaps of ecological environmental quality evaluation in mining areas using remote sensing and their implications for future research. …”
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Investigation and Empirical Analysis of Transfer Learning for Industrial IoT Networks by Preeti Yadav, Vinay Rishiwal, Mano Yadav, Aziz Alotaibi, Vinay Maurya, Udit Agarwal, Satyam Sharma

“…The Industrial Internet of Things Networks (IIoT-N) have revolutionized industrial systems by connecting sensors, devices, and data analytics, creating complex, data-driven environments. However, key challenges persist, such as data diversity, scalability issues, sparse data, anomaly detection, and adapting to changing conditions while managing limited resources. …”
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HRMS-SCD:A High-Resolution Multi-Scene Satellite Imagery Dataset for Comprehensive Land-Cover Semantic Change Detection by P. Guo, P. Guo, S. Yang, H. Zhang, X. Huang, X. Ning, Y. Han, R. Zhang, M. Hao

“…This dataset not only addresses existing gaps but also establishes a robust foundation for advancing deep learning-based semantic change detection, enabling more accurate and comprehensive analysis of complex and diverse land cover changes. …”
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Strategies, practices, and challenges in enhancing quality assurance in qualitative biomedical research: A multi-method study protocol by Hamidreza Khankeh, Mohammad Saatchi, Mahdieh Motie, Shima Shirozhan, Ulrich Dirnagl

“…Background: The qualitative research paradigm is crucial for understanding complex human phenomena, making credibility essential for its findings. …”
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Bibliometric and visual analysis in the field of electroacupuncture’s analgesia and regulation on negative emotion from 2014 to 2024 by Xubo Huang, Jiajie Gao, Yuxin Ding, Jiali Wang, Junfan Fang, Junfan Fang, Jianqiao Fang, Jianqiao Fang, Junying Du, Junying Du

“…The findings provide a roadmap for enhancing the therapeutic applications of EA and underscore its potential in managing complex conditions involving both physical and emotional components.…”
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