Are caffeine effects equivalent between different modes of administration: the acute effects of 3 mg.kg−1 caffeine on the muscular strength and power of male university Rugby Union... by Jason Tallis, Michael, J. Duncan, Neil, D. Clarke, Rhys O. Morris, Ryan, A. Tamilio

“…Small effects of caffeine on CMJ height could not be explained by changes in specific ground reaction force-time characteristics and were not transferable to DJ performance, and effects specific to the SQ RTP exercise underpin the complexity in understanding effects of caffeine on muscular function. …”
Get full text

Therapeutic interventions aimed at cccDNA: unveiling mechanisms and evaluating the potency of natural products by Liyuan Hao, Liyuan Hao, Shenghao Li, Xiaoyu Hu

“…Notably, despite extensive research, no natural product has yet obtained clinical validation for cccDNA clearance, highlighting the significant translational gap between pre-clinical research and clinical application. …”
Get full text

Application of artificial intelligence in palliative care: a bibliometric analysis of research hotspots and trends by Mingxia Pan, Mingxia Pan, Renling Huang, Chenxi Liu, Yuanfang Xiong, Na Li, Huan Peng, Yongqi Liang, Weisheng Gu, Hanjiao Liu, Hanjiao Liu

“…BackgroundPalliative care, essential for improving quality of life in patients with serious illnesses, faces challenges such as resource limitations, workforce shortages, and the complexity of personalized care. AI’s capabilities in data analysis and decision-making offer opportunities to optimize symptom management, predict end-of-life risks, and tailor care plans. …”
Get full text

Navigating Pathways in Prostate Cancer Survivorship: A Comprehensive Review of Challenges, Interventions, and Long-Term Outcomes by Anthony Galvez, Dhruv Puri, Elizabeth Tran, Kassandra Zaila Ardines, Yahir Santiago-Lastra

“…This review explores the complex landscape of prostate cancer survivorship, with a focus on demographic disparities, barriers to care, symptom burden, and treatment patterns. …”
Get full text

Transformer-Driven Inverse Learning for AI-Powered Ceramic Material Innovation With Advanced Data Preprocessing by Murad Ali Khan, Syed Shehryar Ali Naqvi, Muhammad Faseeh, Do-Hyeun Kim

“…K-Nearest Neighbors (KNN) imputation was first applied, improving data accuracy and completeness to address data gaps. Subsequently, Variational Autoencoders (VAE) were used for data augmentation, enriching the dataset’s diversity. …”
Get full text

Recommendations for diagnosis and treatment of the aging male with Klinefelter syndrome by Michael Zitzmann, Andrea Sansone, Emmanuele A. Jannini, Hugh Jones, Alberto Ferlin, Bruno Lunenfeld

“…By providing a structured framework for comprehensive and individualized care, these recommendations aim to bridge existing healthcare gaps, optimize well-being, and enhance the overall quality of life for aging men with KS.…”
Get full text

A One Health approach to the prevention, control, and management of leptospirosis: a scoping review by Khristine L. Sandoval, Kristel Joy S. Cada, Rodel Victor D. Dimasin, Ryan V. Labana

“…It also emphasizes the importance of interdisciplinary collaboration and integrated approaches to effectively address the complex challenges posed by this infectious disease. …”
Get full text

Analysis of Fatigue Life After Application of Compressive Microstresses on the Surface of Components Manufactured by Metal Injection Molding by Jorge Luis Braz Medeiros, Luciano Volcanoglo Biehl, Ismael Cristofer Baierle

“…The metal injection molding (MIM) manufacturing process has made relevant advances for applications in components with complex geometries, small dimensions, and high production volumes. …”
Get full text

Ultrafine‐Resolution Urban Climate Modeling: Resolving Processes Across Scales by Chenghao Wang, Yongling Zhao, Qi Li, Zhi‐Hua Wang, Jiwen Fan

“…Abstract Recent advances in urban climate modeling resolution have improved the representation of complex urban environments, with large‐eddy simulation (LES) as a key approach, capturing not only building effects but also urban vegetation and other critical urban processes. …”
Get full text

Soil Quality Variations Across Different Land Use Patterns in Central Doon Valley of Dehradun, India: A Comparative Study by Vishal Kamboj, Kajal Katoch, Ram Bhushan Prasad Singh, Aditi Bisht

“… Soil is the most basic and yet most complex component of terrestrial ecosystems. It regulates most of the ecosystem processes and provides a large part of the earth’s biodiversity for the physical basis for many human activities. …”
Get full text

A monthly sub-national Harmonized Food Insecurity Dataset for comprehensive analysis and predictive modeling by Melissande Machefer, Michele Ronco, Anne-Claire Thomas, Michael Assouline, Melanie Rabier, Christina Corbane, Felix Rembold

“…Abstract Food insecurity is a complex, multidimensional concept challenging to measure comprehensively. …”
Get full text

Using EEG technology to enhance performance measurement in physical education by Zhaofeng Zhai, Zhaofeng Zhai, Lu Han, Wei Zhang

“…Current research methodologies in this domain primarily rely on behavioral and self-reported data, which ack the precision to capture the complex interplay between physical activity and cognitive-emotional outcomes. …”
Get full text

Photobiomodulation therapy (PBMT) in skeletal muscle regeneration: A comprehensive review of mechanisms, clinical applications, and future directions by Haohua Liu, Umber Cheema, Darren J. Player

“…This review considers the pathophysiologic and molecular mechanisms of muscle repair, with a focus on the imperative of inflammation resolution, activation of satellite cells, mitochondrial ATP generation, and angiogenesis, with consideration of the role of PBMT.We systematically evaluate preclinical and clinical studies, highlighting the translational gaps caused by differences between controlled experimental models and the complex, heterogeneous nature of human muscle injuries. …”
Get full text

Social vulnerability and climate change: a bibliometric analysis by Iskandar Iskandar, Ali Anas, Syamsul Bahri, Firman Menne, Tawakkal Baharuddin

“…The urgent research on social vulnerability and climate change arises because of the complex impacts on society. Climate change increases social vulnerability and exacerbates social and economic inequalities. …”
Get full text

Mass spectrometry-based metabolomic as a powerful tool to unravel the component and mechanism in TCM by Guang-Qin Liao, Hong-Mei Tang, Yuan-Di Yu, Li-Zhi Fu, Shuang-Jiao Li, Mai-Xun Zhu

“…However, challenges remain, including the need for improved data processing standardization, database expansion, and understanding of metabolite-gene-protein interactions. By addressing these gaps, metabolomics can bridge traditional practices and modern biomedical research, fostering global acceptance of TCM. …”
Get full text

Latest Update on lncRNA in Epithelial Ovarian Cancer—A Scoping Review by Katarzyna Kwas, Maria Szubert, Jacek Radosław Wilczyński

“…EOC remains challenging due to its complex molecular pathogenesis, characterized by genetic and epigenetic alterations. …”
Get full text

Efficient resource management using 5G multi-connectivity for high throughput and reliable low latency communication by Snigdhaswin Kar, Prabodh Mishra, Kuang-Ching Wang

“…However, these promising features have critical gaps that need to be filled before they can be fully implemented for mobile applications in complex environments like smart cities. …”
Get full text

A systematic review on the integration of explainable artificial intelligence in intrusion detection systems to enhancing transparency and interpretability in cybersecurity by Vincent Zibi Mohale, Ibidun Christiana Obagbuwa

“…Furthermore, the review highlights critical gaps in standardization and scalability, emphasizing the need for hybrid models and real-time explainability. …”
Get full text

Student Agency as an Enabler in Cultivating Sustainable Competencies for People-Oriented Technical Professions by Denis Rupnik, Stanislav Avsec

“…In this article, we provide theoretical and empirical reflections on the agency of secondary school students acting as an enabler in cultivating sustainable competencies, with the aim of providing new insights regarding how to reduce skill gaps in people-oriented technical professions. For this study, we used a complex mixed methods research design consisting of three sequential phases. …”
Get full text

Modeling of Conventional Heat Pipes with Capillary Wicks: A Review by Roberta Caruana, Manfredo Guilizzoni

“…Therefore, future research should address these gaps, to enhance the applicability of CHPs across different fields and operating conditions. …”
Get full text