Common variable immunodeficiency disorder: a clinical case by E. A. Sobko, I. V. Demko, I. A. Soloveva, A. Yu. Kraposhina, N. V. Gordeeva, D. A. Anikin, N. S. Pronkina, O. P. Ischenko

“…Thus, a variety of clinical forms of primary immunodeficiency, lack of awareness of doctors about this pathology, complexity of immunological examination in the general medical network lead to the fact that CVID is not diagnosed for long terms, and patients do not receive the necessary pathogenetic therapy. …”
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Development of a Method for Obtaining Nanoscale Magnesium Carbonate Stabilized with Chitosan as the Basis of Scaffold Matrices for Regenerative Medicine by A. V. Blinov, Z. A. Rekhman, A. A. Gvozdenko, M. A. Yasnaya, M. A. Kolodkin, M. A. Taravanov

“…The presented work is intended to fill this gap. Its objective is to create a synthesis method and study the properties of nanoscale magnesium carbonate.Materials and Methods. …”
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TULIP: The UK Life Induction Programme by Aman Sharma, Harjinder Kainth

“…TULIP aims to bridge the gap between international training and UK practice, fostering a more inclusive and supportive environment for all healthcare professionals…”
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YOLO-MECD: Citrus Detection Algorithm Based on YOLOv11 by Yue Liao, Lerong Li, Huiqiang Xiao, Feijian Xu, Bochen Shan, Hua Yin

“…However, research in this critical area remains notably insufficient. To bridge this gap, we conducted in-depth experiments using a custom dataset of 1200 citrus images and proposed a lightweight YOLO-MECD model that is built upon the YOLOv11s architecture. …”
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Precision Weed Control Using Unmanned Aerial Vehicles and Robots: Assessing Feasibility, Bottlenecks, and Recommendations for Scaling by Shanmugam Vijayakumar, Palanisamy Shanmugapriya, Pasoubady Saravanane, Thanakkan Ramesh, Varunseelan Murugaiyan, Selvaraj Ilakkiya

“…To address this knowledge gap, our review analyzes 155 articles and provides a comprehensive understanding of PWC challenges and needed interventions for scaling. …”
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Evolution of microbial carbon sequestration potential in farmland soil driven by natural restoration in coal mine subsidence area by Chunming HAO, Yantang WANG, Sihai YI, Shuo LIU

“…To address this knowledge gap, this study selected coal mining subsidence areas as the research object and systematically collected soil samples from farmlands at various stages of natural recovery. …”
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Barriers to the implementation of large-scale electronic health record systems in primary healthcare centers: a mixed-methods study in Saudi Arabia by Haitham Alzghaibi, Hayley A. Hutchings

“…This study fills a research gap by providing evidence-based recommendations for optimizing large-scale EHRS implementation in healthcare settings, particularly in resource-constrained environments.…”
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The dynamics of learning styles and adaptive flexibility in quantity surveying education: implications for academic performance by Mylan Jonas, Gerrit Crafford, Sibulelokuhle Xulaba, David Edwards

“…Overall, this research illuminates the complexities inherent in the learning processes of specialised educational fields. …”
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Transition from care experiences of youth aged 13 to 23 living with fetal alcohol spectrum disorder in Canada: A scoping review by Michele L. Palk, Christine Wekerle

“…Four main themes highlighting the complexities of living and planning for youth with FASD were identified. …”
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Overview of Singapore’s One Health Strategy by Hao Yi Tan

“…The One Health approach integrates human, animal, and environmental health to address complex challenges like emerging zoonotic diseases and antimicrobial resistance (AMR). …”
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Remimazolam in children: a comprehensive narrative review by Tom G. Hansen, Thomas Engelhardt

“…These include age-specific dosing strategies, long-term safety considerations, and its efficacy in children with comorbid conditions or undergoing complex procedures. Addressing these gaps will require robust clinical trials and large-scale observational studies. …”
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Cancer survivorship in low- and middle-income countries: challenges, needs, and emerging support strategies by Gustavo Rodrigues dos Anjos, Gustavo Rodrigues dos Anjos, Guilherme Falcao Machado, Guilherme Falcao Machado, Cassiano Pereira de Barros, Cassiano Pereira de Barros, Victor Piana de Andrade, Rui Monteiro de Barros Maciel, Lucas Leite Cunha, Lucas Leite Cunha, Lucas Leite Cunha

“…For childhood cancer survivors, late effects like chronic viral infections and cognitive impairments are documented, yet systematic follow-up remains limited. To bridge these gaps, LMICs require innovative care models, such as non-profit partnerships and community-based interventions, to meet the complex needs of survivors. …”
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Biological foundations of successful bacteriophage therapy by Carola Venturini, Aleksandra Petrovic Fabijan, Alicia Fajardo Lubian, Stefanie Barbirz, Jonathan Iredell

“…Phage–bacterium interactions are complex and diverse, characterized by co‐evolution trajectories that are significantly influenced by the environments in which they occur (mammalian body sites, water, soil, etc.). …”
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Exploring the tumor microenvironment in diffuse intrinsic pontine glioma: immunological insights and therapeutic challenges by An Coosemans, Esther Hulleman, Bieke Van den Ende, Matteo Riva, Frederik De Smet, Sandra Jacobs

“…Recent studies have begun to reveal the complex and heterogeneous immune landscape of DIPG, highlighting distinct immunological subgroups. …”
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Lipedema: exploring pathophysiology and treatment strategies – state of the art by Fabio Kamamoto, Jaqueline Munaretto Timm Baiocchi, Bernardo Nogueira Batista, Renan Diego Américo Ribeiro, Débora Aparecida Oliveira Modena, Vitor Cervantes Gornati

“…This review aims to fill gaps in knowledge of this field, to support more informed management of lipedema. …”
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Unveiling the Interrelations Between Migration, Climate Change, and Energy Transitions in the Context of Socioeconomic Disparities by Katarzyna Łukaniszyn-Domaszewska, Katarzyna Mazur-Włodarczyk, Marian Łukaniszyn

“…The review identifies key gaps in the literature, especially regarding the economic and social implications of these interconnected factors. …”
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Advancements in precision medicine: multi-omics approach for tailored metformin treatment in type 2 diabetes by Najeha Rizwana Anwardeen, Khaled Naja, Mohamed A. Elrayess, Mohamed A. Elrayess

“…This review explores the different molecular signatures to uncover how the complex interplay between genetics, metabolic profiles, and gut microbiota can shape individual responses to metformin. …”
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Application of Multiple-Criteria Decision-Making Technology in Emergency Decision-Making: Uncertainty, Heterogeneity, Dynamicity, and Interaction by Tao Li, Jiayi Sun, Liguo Fei

“…As a scientific method, multiple-criteria decision-making (MCDM) technology has gradually become an important tool for solving complex decision-making problems in emergency management. …”
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Decarbonising digital infrastructure and urban sustainability in the case of data centres by Felicia H. M. Liu, Karen P. Y. Lai, Bertrand Seah, Winston T. L. Chow

“…Abstract This paper critically assesses the complex interplay between urban transitions of digitisation and sustainability. …”
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Processus de mise en œuvre de la réforme des études en masso-kinésithérapie par une équipe de direction : entre traduction, dynamiques d’innovation et enrôlement des formateurs... by Thérèse Perez-Roux, Eric Maleyrot

“…The leadership developed reveals gaps and changes generated by such a project. A number of tensions linked to the trainers’ reform understanding are thus identified. …”
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