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Biochemical and structural characterization of Rab3GAP reveals insights into Rab18 nucleotide exchange activity
Published 2025-01-01“…Abstract The heterodimeric Rab3GAP complex is a guanine nucleotide exchange factor (GEF) for the Rab18 GTPase that regulates lipid droplet metabolism, ER-to-Golgi trafficking, secretion, and autophagy. …”
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182
Exosome-Derived microRNAs: Bridging the Gap Between Obesity and Type 2 Diabetes in Diagnosis and Treatment
Published 2024-12-01Get full text
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183
Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects
Published 2024-12-01“…By providing a deeper knowledge of the complex functions these probiotics play in both human and animal health, our analysis will direct future studies and developments in this rapidly developing field.…”
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The main characteristics of the leader channel during breakdown of a long air gap by high pulse voltage
Published 2025-07-01“…Calculation-experimental determination of basic descriptions of plasma channel of leader at an electrical breakdown of long air gap in the double-electrode discharge system (DEDS) «edge-plane» by artificial electricity of high pulse voltage of positive polarity. …”
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186
Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps
Published 2024-03-01“…We also show that both RhoGAP families have undergone evolution under positive selection and that almost all of these RhoGAPs lost their GAP activity and GTPase binding ability due to substitutions in key amino acids. …”
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187
Computational Complexity of Isometric Tensor-Network States
Published 2025-04-01Get full text
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188
The Antimicrobial Efficacy of Copper Complexes: A Review
Published 2025-05-01“…Mechanistically, copper complexes induce reactive oxygen species (ROS) generation, inhibit enzyme function, cause DNA cleavage, and compromise cell membrane integrity. …”
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189
Study on the Complexity Evolution of the Aviation Network in China
Published 2025-07-01“…This study presents a pioneering analysis of China’s aviation network evolution (1990–2024) by integrating temporal dynamics into a network density matrix theory, addressing critical gaps in prior static network analyses. Unlike conventional studies focusing on isolated topological metrics, we introduce a triangulated methodology: ① a network sequence analysis capturing structural shifts in degree distribution, clustering coefficient, and path length; ② novel redundancy–entropy coupling quantifying complexity evolution beyond traditional efficiency metrics; and ③ economic-network coordination modeling with spatial autocorrelation validation. …”
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190
Trends of breastfeeding indicators in Brazil from 1996 to 2019 and the gaps to achieve the WHO/UNICEF 2030 targets
Published 2023-09-01“…Statistical analyses considered the survey’s complex sample design for each database.Results EIBF increased from 36.3% (95% CI 33.6% to 39.0%) in 1996 to 60.9% (95% CI 56.5% to 65.3%) in 2006 (statistically significant) and 62.5% (95% CI 58.3% to 66.6%) in 2019. …”
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191
Trends, outcomes and knowledge gaps in mobile apps for reproductive endocrinology and infertility: a scoping review protocol
Published 2024-12-01“…Introduction Infertility is a complex condition that affects millions worldwide, with significant physical, emotional and social implications. …”
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192
Path and Practice of Gap Management in National Parks: A Comparison Between China and the US and Inspirations Therefrom
Published 2025-02-01“…In summary, both China and the US face similar challenges in gap management within national parks, primarily related to land ownership disparities, diverse land functions, and the complex coordination of multiple interests. …”
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193
A smart soil framework law proposal from Italy: Bridging the gap between policy and implementation
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Progressive multi-subspace fusion for text-image matching
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196
The Tech-Enabled Shopper Impacting a Phygital Retail Complex System Stimulated by Adaptive Retailers’ Valorization of an Increasingly Complex E-Commerce
Published 2025-02-01“…The rise of the experience economy, driven by disruptive technologies delivering innovative experiences, has transformed the interactions between tech-enabled shoppers and the phygital retail complex system. An important knowledge gap is addressed in our study by evaluating shoppers’ perceptions of disruptive technologies and the adaptive challenges that retailers face in securing consistency within a highly complex e-commerce landscape shaped by transformative interactions. …”
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Trends in Gaps of Care for Patients With Congenital Heart Disease: Implications for Social Determinants of Health and Child Opportunity Index
Published 2024-10-01“…Background Lifelong continuity of care is essential for patients with congenital heart disease (CHD) to maximize health outcomes; unfortunately, gaps in care (GIC) are common. Trends in GIC and of social determinants of health factors contributing to GIC are poorly understood. …”
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Luminescent, optical, magnetic and metamaterial behavior of cerium complexes
Published 2019-09-01“…The complexes of cerium with nitrogen, oxygen and sulfur donor ligands were prepared by conventional method. …”
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