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841
Antifungal Activity of Selected Naphthoquinones and Their Synergistic Combination with Amphotericin B Against <i>Cryptococcus neoformans</i> H99
Published 2025-06-01“…The emergence of antifungal resistance and toxicity of conventional treatment underscore the urgent need for novel therapeutic approaches. Combination therapies represent a promising strategy to enhance efficacy and overcome resistance. …”
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842
The component-to-trait relationship between intolerance of uncertainty and obsessive–compulsive personality traits: a network analysis
Published 2025-07-01“…Results In the IU-OCPT network, the strongest edges connecting IU and OCPT communities are “Unforeseen events upset me greatly” (IU1) and “Rigidity” (OCPT8), “One should always look ahead so as to avoid surprises” (IU3) and “Miserliness” (OCPT7), “It frustrates me not having all the information I need” (IU2) and “Need for control” (OCPT6), “The smallest doubt can stop me from acting” (IU11) and “Rigidity” (OCPT8). …”
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843
Anthropology and demography
Published 2013-01-01“…Some of the epistemological issues are mentioned, as well as a need to apply different theoretical perspectives to better understand demographic behavior (especially in Europe) and to better understand certain cultural components that shape this behavior. …”
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844
Genetic diversity and population structure of the endangered medicinal plant Ferula sinkiangensis
Published 2025-04-01“…These findings underscore the urgent need for conservation efforts that employ both in-situ and ex-situ approaches to conserve F. sinkiangensis.…”
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845
150 Evaluating ChatGPT’s role in enhancing mental health care for Hispanic LGBTTQI+ young adults: A comparative study
Published 2025-04-01“…Objectives/Goals: Evaluate the effectiveness of ChatGPT as a complementary tool for addressing the mental health needs of Hispanic LGBTTQI+ young adult patients. …”
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846
Innovative Approach: Exploring the Efficacy of Red Ginger Infusion Therapy in Hypertension Management
Published 2025-03-01“…Conclusion:Red ginger infusion therapy shows promise as a complementary treatment for hypertension, but more comprehensive studies are needed to confirm its long-term benefits. …”
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847
Assessment of Confirmed Clinical Hypersensitivity to Rituximab in Patients Affected with B-Cell Neoplasia
Published 2020-01-01“…The 12-step desensitization protocol is very effective and assumable within healthcare practice. There is a need to determine the mechanism underlying the infusion reaction in a large proportion of cases due to the risk of future drug exposure.…”
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848
Advancing Underwater Vision: A Survey of Deep Learning Models for Underwater Object Recognition and Tracking
Published 2025-01-01“…Promising future directions are also discussed, emphasizing the need for domain adaptation techniques to improve generalizability, lightweight architectures for real-time performance, and multi-modal data fusion to enhance interpretability and robustness. …”
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849
The Pseudotyped Replication-Deficient VSV with Spike from PEDV Induces Neutralizing Antibody Against PEDV
Published 2025-02-01“…Despite the availability of existing vaccines, there is a critical need for novel vaccine platforms that ensure robust protection while maintaining safety. …”
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850
Parents’ Perspectives on the Use of Virtual Reality in Pediatric Chronic Pain Management: Qualitative Study
Published 2025-08-01“…However, there are several potential challenges that need to be addressed to improve the accessibility of VR technology for use in pediatric and adolescent chronic pain management. …”
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851
Role of histone deacetylases and sirtuins in the ischaemic stroke: a protocol for a systematic review and meta-analysis of animal studies
“…Currently, the treatment of acute ischaemic stroke through reperfusion has posed several challenges, raising the need for complementary options to protect the ischaemic penumbra. …”
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852
El cuento motor como recurso didáctico provocativo para fomentar la cooperación y la empatía (Motor story as a didactical and provocative resource to promote cooperation and empat...
Published 2022-02-01“…The motor story was implemented in two groups of 3rd Primary from two different public schools and, in a complementary way, in two events aimed at teacher training. …”
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853
The Impact of Low-Fidelity Three-Dimensional-Printed Models of the Equine Distal Limb and the Canine Forelimb in Teaching Veterinary Anatomy in Practical Classes
Published 2025-05-01“…Limited cadaver availability and health risks from formaldehyde-treated cadavers have increased the need for alternative learning materials in veterinary anatomy education. …”
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854
fNIRS as a biomarker for X-linked neurodevelopmental disorders: leveraging visual processing to assess brain function?
Published 2025-05-01“…However, direct evidence from human cohorts with X-linked NDDs remains limited, highlighting the urgent need for further research to validate the potential of visual fNIRS as a reliable functional biomarker in clinical settings. …”
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855
Toward Personalized Immunotherapeutic Drug Monitoring with Multiplexed Extended‐Gate Field‐Effect‐Transistor Biosensors
Published 2025-05-01“…The selection and optimization of therapies for cancer patients urgently need personalization. Portable point‐of‐care electronic biosensors emerge as a groundbreaking solution contributing to better decision‐making in precision oncology. …”
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856
Soilless Agricultural Systems: Opportunities, Challenges, and Applications for Enhancing Horticultural Resilience to Climate Change and Urbanization
Published 2025-05-01“…High setup costs, energy demands, and the need for technical expertise continue to limit large-scale adoption. …”
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857
Recommendations and guidelines of integrative medicine for COVID-19 care: The APEC project outcome
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858
Exploring dual-coating strategies for probiotic microencapsulation using polysaccharide and protein systems
Published 2025-07-01“…These limitations highlight the need for innovative delivery systems. Dual-coating microencapsulation, combining polysaccharides and proteins, has emerged as a promising solution. …”
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859
From Entry to Outbreak in a High School Setting: Clinical and Wastewater Surveillance of a Rare SARS-CoV-2 Variant
Published 2025-03-01“…These findings underline the critical need for timely research and adherence to quarantine measures to enhance outbreak control efforts.…”
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860
A Comprehensive Overview of Antibacterial Agents for Combating Multidrug-Resistant Bacteria: The Current Landscape, Development, Future Opportunities, and Challenges
Published 2025-02-01“…<b>Conclusions and Future Directions:</b> There is an urgent need to expedite the development of new strategies for treating infections caused by MDR bacteria. …”
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