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Comparative Effectiveness and Safety of Molecular Targeted Therapy Plus PD-(L)1 with or without TACE in Unresectable Hepatocellular Carcinoma: A Retrospective Study
Published 2025-07-01“…Jiangtao Liu,1,* Yan Wang,2,* Li Cui,2 Yan Nie,1 Chao Li,1 Wenle Tan,2 Ye Li,1 Yanhua Bai,1 Tao Wan,3 Bingyang Hu,3 Zhe Liu,3 Minggen Hu,3 Maoqiang Wang,2 Feng Duan2 1Department of Gastroenterology, Hainan Hospital of Chinese People’s Liberation Army (PLA) General Hospital, Sanya, Hainan, 572000, People’s Republic of China; 2Department of Interventional Radiology, Chinese People’s Liberation Army (PLA) General Hospital, Beijing, 100853, People’s Republic of China; 3Faculty of Hepato-Biliary-Pancreatic Surgery, Chinese People’s Liberation Army (PLA) General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Feng Duan, Email duanfeng@vip.sina.comObjective: This study aims to compare the effectiveness and safety of TACE combined with molecular targeted therapy (MTT) plus Programmed death-ligand 1 (PD-(L)1) antibodies versus MTT plus PD-(L)1 antibodies for HCC patients.Methods: Data from HCC patients who received either MTT plus PD-(L)1 (systemic therapy group) or TACE combined with MTT plus PD-(L)1 (combination therapy group) were retrospectively analyzed. …”
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Important tool in our rare disease toolbox: hybrid retrospective-prospective natural history studies serve well as external comparators for rare disease studies
Published 2024-12-01“…In this paper, we discuss considerations for the design, analysis, and conduct of hybrid NHS intended as ECAs for single-arm studies in clinical development programs for rare diseases.…”
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Comparing the effects of motor control exercises and PNF exercises on postural control, strength, endurance, and proprioception in women with chronic nonspecific low back pain
Published 2021-04-01“…The subjects of the experimental groups performed the training program for 8 weeks under the supervision of the instructor and according to the training protocol. …”
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Case-mix adjustment through inverse probability weighting to compare health indicators across territories or providers – an application in the agency for health protection of Milan...
Published 2025-08-01“…Abstract Background The Epidemiological Unit of the Agency for Health Protection of Milan (ATS) calculates several indicators, at hospital and at patients’ residence area level (group level of analysis), with monitoring and programming scopes. …”
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The impact of sports and nutrition interventions on the bodyfat and BMI of primary school children (compared to the effects of a lockdown period while Covid19-pandemic)
Published 2025-08-01“…Body fat was determined by bioelectric impedance analysis using a multi-frequency segmental body composition analyzer. …”
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Robust and sensitive analysis of mouse knockout phenotypes.
Published 2012-01-01“…We explore the use of mixed models using worked examples from Sanger Mouse Genome Project focusing on Dual-Energy X-Ray Absorptiometry data for the analysis of mouse knockout data and compare to a reference range approach. …”
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Ordinary Women and Conservative Talk Radio in the US: A Comparative Study of Women Callers on The Rush Limbaugh Show and The Laura Ingraham Show (2004 -2010)
Published 2015-03-01“…This article explores the status of women callers in comparative focus through a qualitative analysis of conversations between female callers and hosts on The Rush Limbaugh Show and The Laura Ingraham Show in 2004 and 2010. …”
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Development of an integrated engineering education model using multi-body closed system modeling, computational analysis, and signal processing analysis
Published 2025-01-01“…The system aims to enhance the programming capabilities of mechanical engineering students and industrial personnel by providing hands-on experience with the element technologies used in developing automation systems compatible with electronic equipment and programs.…”
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Persistence patterns among secondary STEM teachers: a comparative study of Noyce scholar cohorts in face-to-face and blended learning environments amid the pandemic
Published 2025-05-01“…Recommendations for research include continued evaluation of Noyce projects, longitudinal studies to track STEM teachers’ persistence, and a comprehensive analysis of teacher preparation programs’ effectiveness in promoting teacher retention.…”
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Effects of housing environments on COVID-19 transmission and mental health revealed by COVID-19 Participant Experience data from the All of Us Research Program in the USA: a case–c...
Published 2022-12-01“…Both measures were applied for matched cases and controls of the same race, sex, age group and survey version.Results A multiple logistic regression analysis revealed that housing types with a shared component are significantly associated with COVID-19 infection (OR=1.19, 95% CI 1.1 to 1.3; p=2×10−4), anxiety (OR=1.26, 95% CI 1.1 to 1.4; p=1.1×10−6) and stress (OR=1.29, 95% CI 1.2 to 1.4; p=4.3×10−10) as compared with free-standing houses, after adjusting for confounding factors. …”
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ANALYSIS OF THE VEGETABLE SECTOR IN GIURGIU COUNTY, ROMANIA
Published 2021-01-01Get full text
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ANALYSIS ON THE GRANTING OF DIRECT PAYMENTS IN ROMANIA AND BULGARIA
Published 2017-01-01Get full text
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Programmed Cell Death Ligand 1 (PD-L1) and major Histocompatibility Complex Class I (MHC Class I) Expression Patterns and Their Pathologic Associations in triple-Negative Breast Ca...
Published 2025-02-01“…Ponkrit Kaewkedsri,1 Piyapharom Intarawichian,1 Sirawich Jessadapattarakul,1 Waritta Kunprom,1 Supinda Koonmee,1 Malinee Thanee,1 Ongart Somintara,2 Anongporn Wongbuddha,2 Payia Chadbunchachai,3 Supajit Nawapun,3 Chaiwat Aphivatanasiri1 1Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 3Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Chaiwat Aphivatanasiri, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Email chaiap@kku.ac.thPurpose: This study aims to investigate the clinicopathological characteristics of triple-negative breast cancer (TNBC) in relation to programmed cell death ligand 1 (PD-L1) and major histocompatibility complex class I (MHC class I) expression, with a focus on their prognostic significance.Patients and Methods: A retrospective analysis was conducted on formalin-fixed paraffin-embedded (FFPE) tissue samples from 148 TNBC patients diagnosed between 2008 and 2021. …”
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Scientometric analysis of metadata of articles on the topic "Yoga"
Published 2025-03-01“…The conducted analysis combines network analysis methods, namely, building a co‐authorship network using the Gephi program, and text analytics in the Orange Data Mining program. …”
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Analysis of the incidence of breast cancer in the Krasnoyarsk Territory
Published 2023-06-01“…Materials and methods. An analysis of the incidence of breast cancer in the Krasnoyarsk Territory was performed using the Microsoft Office Excel 2021 program. …”
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