Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

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THE VASCULAR ENDOTHELIUM FUNCTION INDICATORS IN ORAL LIQUID OF IQOS SMOKING ADOLESCENTS by T.M. Popova, O.A. Nakonechna, O.V. Tishchenko, L.S. Kryvenko

“…The salivary endothelin-1 level was measured with ELISA kit. Statistical analysis of the data was carried out using the STATISTICA 7.0 program. …”
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Hemoglobin Concentrations and Prevalence of Anemia During Pregnancy: Results from the Brazilian Maternal and Child Nutrition Consortium by Nathalia Cristina de Freitas-Costa, Thais Rangel Bousquet Carrilho, Paula Normando da Costa, Helena M Constante, Elizabeth Fujimori, Ana Paula Sayuri Sato, Gilberto Kac, Adauto Emmerich Oliveira, Alane Cabral Menezes de Oliveira, Ana Paula Esteves Pereira, Ana Paula Sayuri Sato, Antônio Augusto Moura da Silva, Carolina Abreu de Carvalho, Caroline de Barros Gomes, Claudia Leite de Moraes, Claudia Saunders, Cristina Garcia de Lima Parada, Daniela Saes Sartorelli, Dayana Rodrigues Farias, Denise Cavalcante de Barros, Denise Petrucci Gigante, Djanilson Barbosa dos Santos, Edson Theodoro dos Santos Neto, Elisa Maria de Aquino Lacerda, Elizabeth Fujimori, Fernanda Garanhani de Castro Surita, Flávia Farias Lima, Gilberto Kac, Helena Mendes Constante, Iracema de Mattos Paranhos Calderon, Isabel Oliveira Bierhals, Isaac Suzart Gomes-Filho, Jane de Carlos Santana Capelli, Jerusa da Mota Santana, José Guilherme Cecatti, Juliana dos Santos Vaz, Juraci Almeida Cesar, Katrini Guidolini Martinelli, Lívia Castro Crivellenti, Luana Patrícia Marmitt, Marco Fabio Mastroeni, Maria Angélica A Nunes, Maria Antonieta de Barros Leite Carvalhaes, Maria do Carmo Leal, Maria Inês Schmidt, Maria Fernanda Larcher de Almeida, Mayra Pacheco Fernandes, Michael Eduardo Reichenheim, Michele Drehmer, Mônica Araujo Batalha, Nathalia Cristina de Freitas-Costa, Patricia de Carvalho Padilha, Renato Passini Junior, Renato Teixeira Souza, Silmara Salete de Barros Silva Mastroeni, Silvia Regina Dias Medici Saldiva, Sílvio O M Prietsch, Simone Seixas da Cruz, Sirlei Siani Morais, Sotero Serrate Mengue, Thaís Rangel Bousquet Carrilho, Vera Lúcia Bosa

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A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation by Marta Castroviejo‐Bermejo, Cristina Cruz, Alba Llop‐Guevara, Sara Gutiérrez‐Enríquez, Mandy Ducy, Yasir Hussein Ibrahim, Albert Gris‐Oliver, Benedetta Pellegrino, Alejandra Bruna, Marta Guzmán, Olga Rodríguez, Judit Grueso, Sandra Bonache, Alejandro Moles‐Fernández, Guillermo Villacampa, Cristina Viaplana, Patricia Gómez, Maria Vidal, Vicente Peg, Xavier Serres‐Créixams, Graham Dellaire, Jacques Simard, Paolo Nuciforo, Isabel T Rubio, Rodrigo Dienstmann, J Carl Barrett, Carlos Caldas, José Baselga, Cristina Saura, Javier Cortés, Olivier Déas, Jos Jonkers, Jean‐Yves Masson, Stefano Cairo, Jean‐Gabriel Judde, Mark J O'Connor, Orland Díez, Judith Balmaña, Violeta Serra

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Outcomes of brexucabtagene autoleucel in patients with relapsed/refractory acute lymphoblastic leukemia with CNS involvement by Ibrahim N. Muhsen, Gregory W. Roloff, Rawan Faramand, Tamer Othman, Yannis Valtis, Noam E. Kopmar, Simone E. Dekker, Matthew Connor, Santiago Mercadal, Timothy E. O'Connor, Kaitlyn C. Dykes, Mohamed Ahmed, Nikeshan Jeyakumar, Amy Zhang, Katharine Miller, Katherine C. Sutherland, Caitlin Guzowski, Vishal K. Gupta, Navneet Majhail, Minoo Battiwalla, Melhem M. Solh, Shahbaz A. Malik, John Mathews, Caspian H. Oliai, Paul Shaughnessy, Luke Mountjoy, Catherine J. Lee, Aaron C. Logan, Stephanie B. Tsai, Jessica T. Leonard, Marc Schwartz, Joshua P. Sasine, Muthu Kumaran, Noelle Frey, Jae H. Park, Divya Koura, Ryan D. Cassaday, Bijal D. Shah, Ibrahim Aldoss, Lori S. Muffly, LaQuisa C. Hill

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Radiomic Model Associated with Tumor Microenvironment Predicts Immunotherapy Response and Prognosis in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma by Jie Sun, Xuewei Wu, Xiao Zhang, Weiyuan Huang, Xi Zhong, Xueyan Li, Kaiming Xue, Shuyi Liu, Xianjie Chen, Wenzhu Li, Xin Liu, Hui Shen, Jingjing You, Wenle He, Zhe Jin, Lijuan Yu, Yuange Li, Shuixing Zhang, Bin Zhang

“…Background: No robust biomarkers have been identified to predict the efficacy of programmed cell death protein 1 (PD-1) inhibitors in patients with locoregionally advanced nasopharyngeal carcinoma (LANPC). …”
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Priority actions for Fusarium head blight resistance in durum wheat: Insights from the wheat initiative by Ambra Viviani, Jemanesh K. Haile, W. G. Dilantha Fernando, Carla Ceoloni, Ljiljana Kuzmanović, Dhondup Lhamo, Yong‐Qiang Gu, Steven S. Xu, Xiwen Cai, Hermann Buerstmayr, Elias M. Elias, Alessia Confortini, Matteo Bozzoli, Gurcharn Singh Brar, Yuefeng Ruan, Samia Berraies, Walid Hamada, Safa Oufensou, Malini Jayawardana, Sean Walkowiak, Salim Bourras, Monika Dayarathne, Julio Isidro y Sánchez, Fiona Doohan, Agata Gadaleta, Ilaria Marcotuli, Xinyao He, Pawan K. Singh, Susanne Dreisigacker, Karim Ammar, Valentyna Klymiuk, Curtis J. Pozniak, Roberto Tuberosa, Marco Maccaferri, Barbara Steiner, Anna Maria Mastrangelo, Luigi Cattivelli

“…A meta‐analysis grouping all quantitative trait loci (QTL) associated with FHB resistance in both bread and durum wheat has been conducted to identify hotspot regions that do not overlap with Rht alleles, which are known to negatively correlate with FHB resistance. …”
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Photoaging smartphone app promoting poster campaign to reduce smoking prevalence in secondary schools: the Smokerface Randomized Trial: design and baseline characteristics by Michael Kreuter, Fabian N Fries, Titus J Brinker, Ute Mons, David A Groneberg, Anil Batra, Werner Seeger, Felix Herth, Julia Holzapfel, Tanja G Baudson, Katharina Sies, Lena Jakob, Hannah Maria Baumert, Marlene Heckl, Ana Cirac, Janina L Suhre, Verena Mathes, Hannah Spielmann, Nancy Rigotti, Tobias Raupach, Henning Gall, Claudia Bauer, Pat Marek, Chase H Harrison, Lava Taha, Andreas Owczarek, Felix J Hofmann, Roger Thomas

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Conditioned media of stem cells from human exfoliated deciduous teeth contain factors related to extracellular matrix organization and promotes corneal epithelial wound healing by Shinri Sato, Yuji Teramura, Yoko Ogawa, Eisuke Shimizu, Masato Otake, Keigo Hori, Takamitsu Kamata, Yujing Shu, Yasuhiro Seta, Akiko Kuramochi, Kazuki Asai, Shota Shimizu, Kazuno Negishi, Masatoshi Hirayama

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Longitudinal data from a school-based intervention - The ACORDA project (Datos longitudinales de un programa intervención en la escuela - proyecto ACORDA) by Luísa Aires, Gustavo Silva, Ana Inês Alves, Ana Filipa Medeiros, Henrique Nascimento, Clarisse Magalhães, Clarice Martins, Petronila Rocha Pereira, Alice Santos-Silva, Luis Belo, Jorge Mota

“…General Linear Models (Repeated Measures Analysis of Covariance) was carried out comparing values at baseline vs. final evaluation, with adjustments for gender and age at baseline. …”
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Identification of Priority Areas for the Control of Soil Erosion and the Influence of Terrain Factors Using RUSLE and GIS in the Caeté River Basin, Brazilian Amazon by Alessandra dos Santos Santos, João Fernandes da Silva Júnior, Lívia da Silva Santos, Rômulo José Alencar Sobrinho, Eduarda Cavalcante Amorim, Gabriel Siqueira Tavares Fernandes, Elania Freire da Silva, Thieres George Freire da Silva, João L. M. P. de Lima, Alexandre Maniçoba da Rosa Ferraz Jardim

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Isolation and characterization of phages ΦZC2 and ΦZC3 against carbapenem-resistant Acinetobacter baumannii, and efficacy of ΦZC3 on A549 cells by Kareem Essam, Azza G. Kamel, Bishoy Maher Zaki, Mohamed Elhadidy, Amal Ahmed Abdel Aziz, Aysam Fayed, Tamer Roshdy, Ayman El-Shibiny

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Circulating PIWI-interacting RNAs in Acute Ischemic Stroke patients by Salman M. Toor, Eman K. Aldous, Aijaz Parray, Naveed Akhtar, Yasser Al-Sarraj, Abdelilah Arredouani, Ghulam Jeelani Pir, Sajitha V. Pananchikkal, Omar El-Agnaf, Ashfaq Shuaib, Nehad M. Alajez, Omar M.E. Albagha

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Enhanced B7-H4 expression in gliomas with low PD-L1 expression identifies super-cold tumors by Yan Zhang, Di Chen, Qiqi Lu, Yu Yao, Gaopeng Li, Chunxia Ji, Ying Qi, Chao Tang, Ji Xiong, Jian Hu, Fatma Betul Aksoy Yasar, Dave S B Hoon, Liangfu Zhou

“…Gene coexpression analysis assessing clusters based on extent of PD-L1/B7-H4 classifier genes expression were investigated in two transcriptome datasets (The Cancer Genome Atlas and Chinese Glioma Genome Atlas). …”
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BRAF inhibitor resistance of melanoma cells triggers increased susceptibility to natural killer cell-mediated lysis by Antoine Toubert, Eric Pasmant, Alexandra Frazao, Louise Rethacker, Géraldine Jeudy, Marina Colombo, Marie-Françoise Avril, Helene Moins-Teisserenc, Marie Roelens, Sophie Dalac, Eve Maubec, Anne Caignard

“…Soluble NKG2D ligands known to regulate the receptor function have been associated to cancer progression. Serum analysis of patients treated with target therapies or IT indicates that soluble forms of NK ligands (MICA, B7H6, programmed cell death ligand 1, and carcinoembryonic antigen cell adhesion molecule 1) may correlate with clinical response.Conclusion These results support strategies combining targeted therapies and NK-based immunotherapies.…”
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Further assessment of a ~2-million-year-old hominin pelvis (DNH 43) from Drimolen Main Quarry, South Africa by Ellie Berg, Ashley S. Hammond, Anna G. Warrener, Mary Shirley Mitchell, Matthew W. Tocheri, Stephanie E. Baker, Andy I.R. Herries, David S. Strait, Caley M. Orr

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HER2-positive breast cancer with invasive micropapillary carcinoma component shows immunosuppressive microenvironment and resistance to neoadjuvant therapy by Lulu Zhang, Lijia Zhou, Anli Yang, Shaoquan Zheng, Keming Chen, Yutian Zou, Qingru Zhou, Daining Wang, Fei Xu, Jiajia Huang, Zhongyu Yuan, Shusen Wang, Yanxia Shi, Peng Sun, Xin An

“…The IMPC group exhibited significantly lower pCR rates compared to the non-IMPC group: 21.6% vs. 47.1% (P = 0.004) overall, 15.0% vs. 28.4% (P = 0.223) in the H-based subgroup, and 27.8% vs. 57.6% (P = 0.017) in the HP-based subgroup. …”
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AERO-MAP: a data compilation and modeling approach to understand spatial variability in fine- and coarse-mode aerosol composition by N. M. Mahowald, L. Li, J. Vira, M. Prank, D. S. Hamilton, H. Matsui, R. L. Miller, P. L. Lu, P. L. Lu, E. Akyuz, D. Meidan, P. Hess, H. Lihavainen, C. Wiedinmyer, J. Hand, M. G. Alaimo, C. Alves, A. Alastuey, P. Artaxo, A. Barreto, F. Barraza, S. Becagli, G. Calzolai, S. Chellam, Y. Chen, P. Chuang, D. D. Cohen, C. Colombi, E. Diapouli, G. Dongarra, K. Eleftheriadis, J. Engelbrecht, C. Galy-Lacaux, C. Gaston, D. Gomez, Y. González Ramos, Y. González Ramos, R. M. Harrison, C. Heyes, B. Herut, B. Herut, P. Hopke, P. Hopke, C. Hüglin, M. Kanakidou, M. Kanakidou, M. Kanakidou, Z. Kertesz, Z. Klimont, K. Kyllönen, F. Lambert, F. Lambert, X. Liu, R. Losno, F. Lucarelli, W. Maenhaut, B. Marticorena, R. V. Martin, N. Mihalopoulos, N. Mihalopoulos, Y. Morera-Gómez, A. Paytan, J. Prospero, S. Rodríguez, S. Rodríguez, P. Smichowski, D. Varrica, B. Walsh, C. L. Weagle, X. Zhao

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Echocardiographic evaluation of myocardial structural and functional changes in patients with stage 5 chronic kidney disease before and after kidney transplantation by M. Sh. Khubutiya, E. V. Shuvalova, O. N. Rzhevskaya, L. T. Khamidova, A. A. Ivannikov, Kh. G. Alidzhanova, A. G. Balkarov, I. V. Dmitriev

“…A retrospective cross-sectional study included 111 individuals of whom 36 patients underwent evaluation for kidney transplant waiting list placement program (Group I), and 51 patients received kidney transplants from deceased donors (Group II). …”
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A prospective observational cohort study of HIV infection in Indonesia: baseline characteristics and one-year mortality by Tuti P. Merati, Evy Yunihastuti, Rudi Wisaksana, Nia Kurniati, Dona Arlinda, Muhammad Karyana, Nugroho H. Susanto, Dewi Lokida, Herman Kosasih, Aly Diana, Lois E. Bang, Melinda Setiyaningrum, Desrinawati M. Amin, Eppy Eppy, Wiwit A. S. N. Cahyawati, Emon W. Danudirgo, I Made Gede Darmaja, Nur Farhanah, Carta A. Gunawan, Usman Hadi, Kurnia F. Jamil, Sudirman Katu, Tambar Kembaren, I Gede Rai Kosa, Danang L. Norosingomurti, Asep Purnama, Ida S. Laksanawati, Adria Rusli, I Ketut Agus Somia, Yanri W. Subronto, Ivan L. Toruan, Renee Ridzon, C. Jason Liang, Aaron T. Neal, Ray Y. Chen, INA-PROACTIVE Study Group

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