Research advances in immune agonists and their nanoparticles for enhancing the immunotherapeutic efficacy of PD-1 inhibitors in malignancies by Renjie Xia, Renjie Xia, Juan Liang, Jianguo Ma, Jianguo Ma, Xiaoyu Du, Xiaoyu Du, Liangbin Ma, Liangbin Ma, Xiongxiong Han, Xiongxiong Han, Yong Wang, Yong Wang, Jianwei Qin, Long Yan

“…This review systematically examines the integration of immune agonists—STING, TLR, CD40, and OX40 agonists—with PD-1 inhibitors to overcome resistance and amplify antitumor immunity. …”
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Efficient Multi-Target Localization Using Dynamic UAV Clusters by Wei Gong, Shuhan Lou, Liyuan Deng, Peng Yi, Yiguang Hong

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Lattice protein folding with variational annealing by Shoummo A Khandoker, Estelle M Inack, Mohamed Hibat-Allah

“…Our findings emphasize the potential of advanced machine learning techniques in tackling complex protein folding problems and a broader class of constrained combinatorial optimization challenges.…”
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Edge-Driven Multiple Trajectory Attention Model for Vehicle Routing Problems by Dapeng Yan, Bei Ou, Qingshu Guan, Zheng Zhu, Hui Cao

“…The vehicle routing problem (VRP), as one of the classic combinatorial optimization problems, has garnered widespread attention in recent years. …”
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Cancer-specific targeting core–shell nanoparticles with magnetic resonance imaging function: Realizing efficient chemo-photothermal synergistic therapy triggered by near-infrared l... by Hongqi Shi, Run Huang, Rui Miao, Miao Wei, Liujun Wu, Yusong Pan, Zhonglei He, Wenxin Wang, Lei Huang

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A Low-Discrepancy and Latency-Aware, Scenario-Sensitive Resource Allocation Approach for Cloud Systems Using Latin Square-Based Improvised Genetic Optimization (LSBGO) by Aman Kumar Routh, Prabhat Ranjan, Asisa Kumar Panigrahy

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INTEGRATED OPTIMIZATION MODEL OF MANUFACTURING AND TRANSPORTATION PROCESSES by R. S. Rogulin, D. E. Pleshanov, P. V. Nechaev

“…This task can be attributed to non-trivial combinatorial problems on decision-making at an enterprise. …”
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A monolithically integrated optical Ising machine by Bo Wu, Wenkai Zhang, Shiji Zhang, Hailong Zhou, Zhichao Ruan, Ming Li, Dongmei Huang, Jianji Dong, Xinliang Zhang

“…Abstract The growing demand for enhanced computational power and energy efficiency has driven the development of optical Ising machines for solving combinatorial optimization problems. However, existing implementations face challenges in integration density and energy efficiency. …”
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Population-Based Redundancy Control in Genetic Algorithms: Enhancing Max-Cut Optimization by Yong-Hyuk Kim, Zong Woo Geem, Yourim Yoon

“…The max-cut problem is a well-known topic in combinatorial optimization, with a wide range of practical applications. …”
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Advancing Cancer Treatment: Innovative Materials in PDT and Diagnostic Integration by Wang Y, Hu C, Li Y, Chen ZS, Zhang L

“…Keywords: precision anti-cancer therapy, photodynamic therapy, integrated diagnosis and treatment, novel nano-systems, tumor targeting, advanced imaging technology…”
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Improved Cosine Similarity-based Artificial Bee Colony Optimization scheme for reactive and dynamic service composition by N. Arunachalam, A. Amuthan

“…Reliable and dynamic composition of web services is considered as essential for ensuring continuous services to the users since they are responsible for integrating varsity of applications in spite of their independency. …”
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β-caryophyllene sensitizes hepatocellular carcinoma cells to chemotherapeutics and inhibits cell malignancy through targeting MAPK signaling pathway by Irum Basheer, Hai Wang, Guangyue Li, Shah Jehan, Ali Raza, Chentao Du, Najeeb Ullah, Dangdang Li, Guangchao Sui

“…Furthermore, RNA-seq analyses of BCP-treated HepG2 cells identified 433 protein-coding DEGs. Integrative analyses revealed five BCP-targeted DEGs regulating the MAPK signaling pathway. …”
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Integrative genomic identification of therapeutic targets for pancreatic cancer by Jimmy A. Guo, Dennis Gong, Kyle Evans, Kazuki Takahashi, Ananya D. Jambhale, Carina Shiau, Patrick Yu, Steven Wang, Wenbo W. Wu, Seema Chugh, Kevin S. Kapner, Julien Dilly, Daniel Zhao, Peter Chen, Eric L. Smith, Joseph D. Mancias, Francisca Vazquez, Harshabad Singh, William L. Hwang, Andrew J. Aguirre

“…Here, we conduct an integrative, genome-scale examination of genetic dependencies and cell surface targets using CRISPR-Cas screening and multi-omic data, including single-nucleus and spatial transcriptomic data from patient tumors. …”
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Synergistic effects of human umbilical cord mesenchymal stem cells/neural stem cells and epidural electrical stimulation on spinal cord injury rehabilitation by Zhiping Mu, Jiaodi Qin, Xiaohua Zhou, Kunzheng Wang

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Integrated Use of System Z for Preferred Answer Set Programming by Marco Wilhelm, Andre Thevapalan, Gabriele Kern-Isberner

“…While ASP excels with an intuitive rule-based syntax, fast solvers, and is suited to solve complex combinatorial search problems, conditionals provide a sophisticated preference-based semantics and yield principled inferences. …”
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Optimizing Rural Connectivity Through Hybrid Wireless-Wireline and Satellite Network Integration by Fareha Nizam, Teong Chee Chuah, Ying Loong Lee

“…Building on these advancements, this paper introduces a novel hybrid wireless-wireline and satellite access network (HWWSAN) framework, which integrates both technologies to enhance network performance, service reliability, and user experience. …”
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Fault localization for automatic train operation based on the adaptive error locating array algorithm by Yanpeng Zhang, Yuxiang Cao

“…Abstract When the combinatorial testing method is used to locate faults in the complex signalling system of high-speed rail in order to prevent the system from being affected by combinatorial testing case explosion, which could results from the masking effects caused by multiple faults, the Minimum Fault Schema (MFS) can be accurately and efficiently located. …”
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An overview of high‐throughput synthesis for advanced high‐entropy alloys by Tong Xie, Weidong Li, Gihan Velisa, Shuying Chen, Fanchao Meng, Peter K. Liaw, Yang Tong

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Comprehensive Evaluation Method for Electric Vehicle Charging Network Service Quality Considering User Satisfaction by Shukang Lyu, Yi Pan, Huiyu Miao, Xiaodong Yuan, Fei Zeng

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Combined Transplantation of Mesenchymal Progenitor and Neural Stem Cells to Repair Cervical Spinal Cord Injury by Seok Voon White, Yee Hang Ethan Ma, Christine D. Plant, Alan R. Harvey, Giles W. Plant

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