Association of p53 codon 72 polymorphisms with expression status of hormone receptors like ER, PR, and HER-2 in invasive ductal breast carcinoma in Bangladeshi women by Md. Zillur Rahman, Md. Jibran Alam, Amlan Bhattacharjee, Md. Azizur Rahman Riyaz, Fahmida Binta Wali, Inzamamul Ismail Shawon, Syeda Rumman Aktar Siddiqui, Laila Khaleda, Mohammad Al-Forkan

“…The specimens were collected from one laboratory in each of the Dhaka and Chattogram cities. p53 codon 72 genotypes were detected using PCR-RFLP. …”
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Chloroplast genome features and phylogenetic analysis of Artemisia parviflora by LI Zhifang, CHEN Liling, LUO Shujie, LIU Tianmeng*

“…The results were as follows:(1)The chloroplast genome of A. parviflora was 151 047 bp, with a typical circular double-stranded tetrad structure, and the GC content was 37.5%.(2)Total 115 unique genes were annotated, including 81 protein-coding genes, 4 rRNA genes, and 30 tRNA genes.(3)Sixty-eight simple sequence repeats(SSRs)and 37 long repeat sequences were detected.(4)The codon usage bias was weak in the A. parviflora chloroplast genome, and natural selection mainly contributed to the codon usage bias. …”
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Genetic diversity and population structure analysis of Indian blackberry (Syzygium cumini L.) using CAAT box‑derived polymorphism (CBDP) and start codon targeted polymorphism (SCoT... by Ajay Kumar, Kanhaiya Singh, Amit Kumar Singh, Jai Prakash, Amit Kumar Goswami, Gyan Prakash Mishra, Vishaw Bandhu Patel, Suman Lata, Anshuman Singh

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HPV disease transmission protection and control by Neil D. Christensen

“…Host control of HPV infections requires both innate and adaptive immunity, but the viruses have developed strategies to escape immune detection. Viral proteins can disrupt both innate pathogen-sensing pathways and T-cell based recognition and subsequent destruction of infected tissues. …”
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Chloroplast Genome of Myristica fragrans: Assembly, Annotation, and Phylogenetic Relationships by Hani Sitti Nuroniah, Aditya Nugroho, Fitri Indriani, Eliya Suita, Bakhtiar Basyah, Susanna Susanna, Ujang Wawan Darmawan, Neo Endra Lelana

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Combinatorial biosynthesis of novel gentamicin derivatives with nonsense mutation readthrough activity and low cytotoxicity by Lihua Yang, Hang Zhai, Tingting Tian, Botong Liu, Xianpu Ni, Huanzhang Xia

“…The premature termination codon (PTC) readthrough activity of genkamicins (GKs) was compared using dual luciferase reporter assay. …”
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Generation and genetic repair of two human induced pluripotent stem cell lines from patients with Epidermolysis Bullosa simplex associated with a heterozygous mutation in the trans... by Spyridon T. Pachis, Veronika Ramovs, Christian Freund, Cristina Has, Karine Raymond

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Mitochondrial genome analysis of the endangered Oreocharis esquirolii: insights into evolutionary adaptation and conservation by Lang Chen, Rong-Rong Yan, Chong-Yi Yang, Li-Zhen Ling, Xin-Xiang Bai, Qi-Fei Ren, Guo-Xiong Hu

“…Positive selection signals were detected in seven coding genes of the O. esquirolii mitogenome, with a potential impact on environmental adaptation. …”
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DETECTION OF SOMATIC MUTATIONS IN THE BRAF GENE BY PYROSEQUENCING by O. P. Dribnokhodova, E. A. Dunaeva, G. V. Leshkina, E. A. Yarygina, A. Yu. Bukharina, Ya. A. Voiciehovskaya, E. V. Borisova, S. K. Bormotova, A. I. Daoud, V. N. Khlavich, K. O. Mironov

“…The technique provided sufficient sensitivity to detect frequent mutations in the 600 codon and allowed the detection of rare mutations. …”
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Molecular Detection of Gene Mutation Related to Drug Resistance in Mycobacterium leprae by Saumya Shukla, Shaina Gaikwad, Dhandapani Sureshgopi, Vivek Kumar Chouksey, Chandrashekhar Pathe, Jerene Mathews, Jitendra Singh, Shashank Purwar, Debasis Biswas, Pushpendra Singh, Anand Kumar Maurya

“…A mutation was identified at codon 91 (alanine [GCA] → valine [GTA]) in the gyrA gene (20%), resulting in an alanine-to-valine change known to cause resistance to ofloxacin. …”
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Detection of Resistant Prevalent Genes for Mycobacterium Tuberculosis by Line Probe Assay by Tejaswini A. Olambe, Pooja G. Shah, Sae Pol, Vaishali Gaikwad, Bhakti Karmalkar, Rajesh Karyakarte

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Phylogenetic analysis and detection of positive selection in the SIRT gene family across vertebrates by Qiuxi Zhou, Xiongtao Yang, Da Li, Jing Li, Ling Peng, Wenwu He

“…Phylogenetic relationships among the seven SIRT gene family members were reconstructed using Bayesian inference. Codon-based models were applied to detect site-specific positive selection, and likelihood ratio tests (LRTs) were used to compare model fits. …”
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Detection and Significance of Cell-Free DNA Mutation in Pleural Effusion in Patients with Advanced NSCLC by Man Qiao, Dongsheng Li, Yuan He, Cen Zhang, Hang Chi, Xiaoqiu Li, QingMing Cui, ShaoYing Li, Ying Jiao, Yuan Wei

“…There were 6 cases (12.00%) with KRAS mutations (single-base substitution mutations), including 4 cases with 12-codon mutation and 2 cases with 13-codon mutation. …”
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Detection of Vgsc-L1014F Allele Knockdown-resistance Mutation in Male Culex quinquefasciatus by Dzikra Nasyaya Mahfudhah, Fistara Lesti Rahmafitria, Teguh Hari Sucipto, Shifa Fauziyah, Mirwa Adiprahara Anggarani, Nuniek Herdyastuti, Sin War Naw, Adiana Mutamsari Witaningrum

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High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations by Nobue Tamamura, Yoshihiko Hagiwara, Hirokazu Kato, Yusuke Ono, Kenji Takahashi, Kazuya Koyama, Hiroki Sato, Tetsuhiro Okada, Hidemasa Kawabata, Yu Ohtaki, Chiho Maeda, Miyuki Mori, Shin-ichi Chiba, Mishie Tanino, Kenzui Taniue, Takashi Anazawa, Ryoji Inaba, Yusuke Mizukami

“…By applying the multi-base primer extension method to the HiDy-CE with control DNA containing known mutations, we detected variant allele frequencies (VAFs) as low as 0.5% for major KRAS hotspot mutation at codon 12 and 13. …”
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Evaluation of usefulness of single-strand conformation polymorphism method for rapid detection of rifampicin-resistant mycobacterium tuberculosis by Tešić Jelena, Lepšanović Zorica, Mirović Veljko

“…SSCP analysis on acrylamide gel detected 56.4% of the rifampicin-resistant M. tuberculosis strains and showed the inability to detect one of the most frequent mutations, TCG®TTG mutation in codon 531 of the rpoB gene, which was shown by automated sequencing.…”
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Nucleic acid amplification-based HER2I655V molecular detection for breast cancer by Bugi Ratno Budiarto, Pimpin Utama Pohan, Desriani

“…Single Nucleotide Polymorphism at codon 655 of HER2 gene has been extensively evaluated for its role as a susceptible biomarker for breast cancer development and the contradictive result of its role has been a debate among researchers as evidenced from case-control studies. …”
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Detection of gyrA Mutation Among Clinical Isolates of Campylobacter jejuni Isolated in Egypt by MAMA-PCR by Mayar Maged Said, Hanan El-Mohamady, Fawkia M. El-Beih, David M. Rockabrand, Tharwat F. Ismail, Marshall R. Monteville, Salwa F. Ahmed, John D. Klena, Mohamed S. Salama

“…C to T alteration was detected by the mismatch amplification mutation assay MAMA PCR. …”
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From chemoproteomic‐detected amino acids to genomic coordinates: insights into precise multi‐omic data integration by Maria F Palafox, Heta S Desai, Valerie A Arboleda, Keriann M Backus

“…Here, we evaluated mapping approaches to match chemoproteomic‐detected cysteine and lysine residues with their genetic coordinates. …”
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Introduction of the hybcell-based compact sequencing technology and comparison to state-of-the-art methodologies for KRAS mutation detection by Agnes Zopf, Roman Raim, Martin Danzer, Norbert Niklas, Rita Spilka, Johannes Pröll, Christian Gabriel, Andreas Nechansky, Markus Roucka

“…The detection of KRAS mutations in codons 12 and 13 is critical for anti-EGFR therapy strategies; however, only those methodologies with high sensitivity, specificity, and accuracy as well as the best cost and turnaround balance are suitable for routine daily testing. …”
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