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16S rRNA sequencing data of fecal microbiota from juvenile female rats following prenatal poly I:C exposureNCBI
Published 2025-06-01“…Polyriboinosinic-polyribocytidylic acid (Poly I:C) belongs to a class of synthetic analogs of double-stranded RNA used to induce MIA in rodents and is widely used in scientific research. …”
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Single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts reveals transcriptional complexity in the insect central complex
Published 2025-05-01“…Here we perform single nuclei RNA sequencing of T2 neuroblast-derived adult neurons and glia. …”
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The Diversity, Richness, and Potential Health and Ecological Role of the Fungal Aerosols in Attica, Greece
Published 2024-12-01“…We studied the taxonomy of aerial mycobiome by DNA extraction, purification, and a barcoded amplicon sequencing method. Overall, we isolated two main fungal phyla Ascomycota and Basidiomycota; in total, 195 species, 121 genera, 83 families, 45 orders, and 17 classes. …”
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Circular RNAs: Biogenesis, Function, and a Role as Possible Cancer Biomarkers
Published 2017-01-01“…Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs) that form covalently closed continuous loop structures, lacking the terminal 5′ and 3′ ends. …”
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A snapshot of the role of estrogen‐regulated divergent non‐coding transcripts
Published 2025-06-01“…Abstract Recent high‐throughput sequencing technologies have discovered various polymerase II transcribed transcripts. …”
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CO35 | Bleeding phenotype characterization in patients with congenital bleeding disorders: a multigenic approach using next generation sequencing to identify coagulation-modulatin...
Published 2025-08-01“…Sequencing was performed on the Illumina NextSeq550 platform. …”
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Tumour-associated macrophage infiltration differs in meningioma genotypes, and is important in tumour dynamics
Published 2025-05-01“…However, their role in meningiomas, especially in relation to genomic mutations, remains poorly understood. …”
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Mechanism of circRNA_4083 Circularization and Its Role in Regulating Cell Viability
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Advancing the accuracy of tyrosinase inhibitory peptides prediction via a multiview feature fusion strategy
Published 2025-02-01“…Secondly, we applied a multi-view feature fusion (MVFF) strategy to extract and explore probability and category information embedded in TIPs, employing several machine learning (ML) algorithms coupled with different commonly used sequence-based feature encodings. Then, we employed resampling approaches to address the class imbalance issue. …”
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Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung ade...
Published 2024-11-01“…This study also emphasizes that during the transdifferentiation process of GGN– and PSN–LUAD, IFN-γ activates the STAT1 signaling pathway to regulate the activation of CXCL9 + TAMs, and further recruiting CD8 + Trm cells and activating T cells through MHC class I antigen presentation. The role of the IFN-γ/STAT1 pathway in the occurrence and development of LUAD was further validated by animal experiments. …”
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Comprehensive molecular epidemiology of Acinetobacter baumannii from diverse sources in Nigeria
Published 2025-03-01“…Abstract Background Acinetobacter baumannii, a Gram-negative bacterium, is a public health threat due to its role in nosocomial infections and increasing antibiotic resistance. …”
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B-cell immunodeficiency associated with polynucleotide kinase 3′-phosphatase (PNKP) deficiency
Published 2025-08-01“…Background: DNA repair is crucial for maintaining genomic integrity and plays a significant role in the immune system. Defects in DNA repair pathways are often associated with immunodeficiency, including B-cell defects, which are consistent with the need for DNA repair during V(D)J recombination, class switching, and somatic hypermutation during B-cell maturation. …”
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A review on the role of MiR-193a-5p in oncogenesis and tumor progression
Published 2025-03-01“…They also play a crucial role in disease progression, invasion, and metastasis. …”
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HLA II genes distribution in Epstein–Barr virus-associated nasopharyngeal carcinoma and other tumors of the oral cavity patients in Russia
Published 2018-05-01“…In the literature there are contradictory information about HLA genes, which determine the predisposition to the emergence of these tumors, and their role in the initiation and formation an immune response to EBV proteins.Objective: to study the distribution of the of DQA1-, DQB1-, DRB1-HLA class II gene variants associated with respectively the risk or resistance to the development of NPC and OOCT and with a high and low level of antibody response to EBV main proteins. …”
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The role of B lymphocyte subsets in nephrotic syndrome: functions, mechanisms, clinical significance and future perspectives
Published 2025-08-01“…B lymphocytes play a critical role in the pathogenesis of nephrotic syndrome (NS). …”
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The current state of knowledge on the role of NKG2D ligands in multiple sclerosis and other autoimmune diseases
Published 2025-01-01“…The activating receptor belonging to the NKG2D is stimulated by specific ligands: in humans these are major histocompatibility complex (MHC) class I polypeptide–related sequence A (MICA) and MHC class I polypeptide-related sequence B (MICB) proteins and UL16 binding 1–6 proteins (ULBP1-6). …”
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