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High prevalence of trimethoprim-resistance cassettes in class 1 and 2 integrons in Senegalese Shigella spp isolates
Published 2010-02-01“…The class 1 integrons detected contained dfr and aadA cassettes, alone or in combination (dfrA5/dfrA15, or dfrA15-aadA1, dfrA1-aadA2), and an atypical cassette array with an insertion sequence (oxa30-aadA1-IS1). …”
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Differential prognostic roles and clinical implications of mitochondrial and genomic tRNA-derived fragments in colorectal liver metastases
Published 2025-07-01“…Transfer RNA-derived fragments (tRFs), a novel class of small non-coding RNAs (sncRNA), regulate gene expression, stress response, and immune functions in cancer. …”
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Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples
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Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
Published 2009-02-01“…We hypothesised that this environmental candidate might interact with inherited factors and sought responsive regulatory elements in the MHC class II region. Sequence analysis localised a single MHC vitamin D response element (VDRE) to the promoter region of HLA-DRB1. …”
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The role of glycoproteins in nasopharyngeal carcinoma pathogenesis
Published 2024-09-01“…Here, data on a specific class of proteins, glycoproteins, involved in tumorigenesis of NPCs are summarized, with a focus on a few of the best-studied ones. …”
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Roles of circRNAs in viral pathogenesis
Published 2025-03-01“…Based on the advances in sequencing technologies and bioinformatics, multiple reports have suggested that viruses and other microorganisms may encode circRNA-like molecules, providing new insights into the physiological and pathological roles of circRNAs. …”
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De l’usage (in)efficace du questionnement par l’enseignant en classe de FLE au primaire
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Combining sequencing approaches to fully resolve a carbapenemase-encoding megaplasmid in a Pseudomonas shirazica clinical strain
Published 2019-01-01“…Horizontal transfer of plasmids plays a pivotal role in dissemination of antibiotic resistance genes and emergence of multidrug-resistant bacteria. …”
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Analysis by next-generation sequencing of bacterial communities in Japanese cedar logs buried for 2 years for ground improvement
Published 2025-03-01“…Next-generation sequencing was employed to analyze the bacterial communities within the logs and the surrounding soil. …”
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Patterns of Variation in the Usage of Fatty Acid Chains among Classes of Ester and Ether Neutral Lipids and Phospholipids in the Queensland Fruit Fly
Published 2023-11-01“…Modern lipidomics has the power and sensitivity to elucidate the role of insects’ lipidomes in their adaptations to the environment at a mechanistic molecular level. …”
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Comprehensive analysis of amino acid sequence diversity at the F protein cleavage site of Newcastle disease virus in fusogenic activity.
Published 2017-01-01“…The VFcs is only found in the Class II cluster of viral classification and not in Class I. …”
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L’intégration des TIC dans la séquence pédagogique en espagnol : le concept d’espace langue
Published 1999-06-01Get full text
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Topological Sequences Connected With Inverse Graphs of Finite Flexible Weak Inverse Property Quasigroups: An Approach From Polynomials to Machine Learning
Published 2025-01-01“…The structural characteristics of flexible weak inverse property quasigroups are very close to the conventional group structures, and the class of these nonassociative groups plays an important role in real-time applications. …”
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Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome
Published 2025-08-01“…In conclusion, the predominance of GBS-associated LOS classes, characterized by class-specific nucleotide changes and elevated phase variation, may play a critical role in the pathogenesis of GBS. …”
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RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melan...
Published 2025-01-01“…We found alterations in the secretion profile of immune regulatory factors and immune‐related pathways robustly suppressed in tumours with high RECQL4 levels, underscoring its crucial role in fostering immune evasion. Mechanistically, we identified RECQL4‐mediated regulation of major histocompatibility complex class II molecule expression and uncovered class II major histocompatibility complex transactivator as a mediator bridging this regulation. …”
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Prevalence and characterization of class I integrons in multidrug-resistant Escherichia coli isolates from humans and food-producing animals in Zhejiang Province, China
Published 2025-02-01“…Abstract Class I integrons have garnered significant attention due to pivotal roles in the dissemination of antimicrobial resistance genes (ARGs), which impose risks to public health and food safety. …”
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Prognostic value of HLA class I expression in patients with cutaneous melanoma and soft tissue sarcomas treated with cancer-testis antigens-based vaccine
Published 2025-02-01“…Aim: To assess the predictive and prognostic role of HLA class I expression in patients with melanoma (Mel), and soft tissue sarcomas (STS) treated with autologous dendritic cell vaccine (DCV) (CaTeVac). …”
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