The role of complete exomic sequencing in the administration of targeted drugs in patients with multiform glioblastoma by A. V. Kaminskiy, N. P. Zverev, A. A. Lyakhovets, D. R. Naskhletashvili, M. A. Gairyan, A. A. Isaev, D. N. Khmelkova, I. L. Plaksa

Get full text

Molecular evolution of TRPC4 regulatory sequences supports a role in mammalian thermoregulatory adaptation by Robert S. Cornman

Get full text

Mapping Integron-Associated AMR Genes in Whole Genome Sequences of <i>Salmonella</i> Typhimurium from Dairy Cattle by Sami Ullah Khan Bahadur, Nora Jean Nealon, Joshua B. Daniels, Muhammad Usman Zaheer, Mo Salman, Sangeeta Rao

“…Veterinary Diagnostic Laboratories between 2009 and 2012. <b>Methods:</b> Class I integrons were sequenced from PCR-amplified products. …”
Get full text

Antimicrobial susceptibility, virulence characteristics, and incidence of class 1 and 2 integrons in salmonella infantis isolated from clinical cases in broilers by Özkan ASLANTAŞ, Süheyla TÜRKYILMAZ

Get full text

Characterization of a Novel Sequence Type (ST) 6758 Klebsiella Pneumoniae and the Role of IncX3 Plasmid in the Transmission of blaNDM by Zhang Y, Li Q, Li L, Guo H, He F

Get full text

Long read whole genome sequencing-based discovery of structural variants and their role in aetiology of non-syndromic autism spectrum disorder in India by Jhanvi Shah, Debasrija Mondal, Deepika Jain, Priti Mhatre, Ketan Patel, Anand Iyer, Manoj Pandya, Bhargavi Menghani, Gayatri Dave, Jayesh Sheth, Frenny Sheth, Shweta Ramdas, Harsh Sheth

“…Structural variants (SVs) detected using long-read whole genome sequencing (lrWGS) are a relatively new class of variants implicated in neurodevelopmental disorders. …”
Get full text

Unravelling the prognostic and operative role of intratumoural microbiota in non‐small cell lung cancer: Insights from 16S rRNA and RNA sequencing by Fuling Mao, Zixuan Hu, Ruifeng Shi, Hongbing Zhang, Zihe Zhang, Yongwen Li, Xuanguang Li, Penghu Gao, Jinhui Li, Minghui Liu, Hongyu Liu, Jun Chen

Get full text

Des normes professionnelles à caractère doxique aux difficultés de mise en œuvre de séquences d’investigation en classe de sciences : comprendre les déterminations de l’action... by Corinne Marlot, Ludovic Morge

Get full text

Certain Class of Generating Functions for the Incomplete Hypergeometric Functions by Junesang Choi, Praveen Agarwal

Get full text

Transcriptome Sequencing and Bioinformatic Analysis of Astragalus sinicus ‘Yuelvfei No. 1’ by Jingyu LI, Yan GU, Liping GONG, Zijian FU, Jiahao ZHONG, Jihua WANG

“…R genes also play a crucial role in the interaction between legumes and rhizobia, and we identified 64 members of the largest class of R genes, NBS genes. …”
Get full text

Molecular characterisation of class I integrons in clinical multidrug-resistant Enterococcus spp. by Yasir Adil Jabbar Alabdali

“…The variable region of class 1 integrons was amplified using Polymerase Chain Reaction (PCR), and the resulting ∼2000 bp amplicons were sequenced. …”
Get full text

Protocol for genetic dissection of class switch recombination using genome-editing tools by Pengfei Dai, Tingting Liu, Dingpeng Yang, Yifeng Luo, Liu Daisy Liu, Xia Xie, Yafang Shang, Xiaojing Liu, Fei-Long Meng

“…Here, we present a protocol for inducing class switch recombination using base editors or CRISPR-Cas9. …”
Get full text

Comparative analysis of amino acid sequence level in plant GATA transcription factors by Mangi Kim

“…Through comparative sequence analysis, I identify conserved domains and structural features that enhance the understanding functional roles, evolutionary conservation, and lineage-specific adaptations of GATA TFs. …”
Get full text

Investigation of protists in Momoge wetland (China) through metagenomic next-generation sequencing by Yuting Huang

“…In order to reveal community structure and diversity of protists in Momoge wetland, metagenomic next-generation sequencing (mNGS) was performed. The main results are as follows: 1) A total of 224 species were identified, belonging to 17 phyla, 32 classes, 75 orders, 94 families and 146 genera. …”
Get full text

The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells by Yu Chen, Siyuan Sun, Chenxu Lu, Yixuan Li, Bing Fang, Xiangfeng Tang, Xuepeng Li, Weiru Yu, Yumei Lei, Longjie Sun, Ming Zhang, Jiazeng Sun, Ping Liu, Yongting Luo, Xingwang Zhao, Jing Zhan, Libing Liu, Rong Liu, Jiaqiang Huang, Ziwei Yi, Yifei Yu, Weihan Xiao, Zheng Ding, Lei Li, Dan Su, Fazheng Ren, Changchang Cao, Ran Wang, Wenbiao Shi, Juan Chen

Get full text

A Reassessment of Phylogenetic Relationships in Class Oligohymenophorea (Protista, Ciliophora) Based on Updated Multigene Data by Bailin Li, Yumeng Song, Xiang Wang, Qiyue Zhao, Menghan Liu, Lihui Liu, Xuming Pan, Zhenzhen Yi

“…The main findings are: (1) Utilizing multiple genes is instrumental in improving phylogenetic relationships within class Oligohymenophorea; (2) class Oligohymenophorea is divided into two distinct groups: (i) encompassing the subclass Hymenostomatia, Scuticociliatia, Apostomatia, Astomatia, and Urocentria; and (ii) comprising the subclasses Peniculia and Peritrichia; (3) Revising the phylogenetic placement of the subclass Urocentrida reveals its transitional role as a taxon between Group I and Group II. …”
Get full text

consHLA: a next generation sequencing consensus-based HLA typing workflow by Rachel Bowen-James, Weilin Wu, Marie Wong-Erasmus, Julian M. W. Quinn, Chelsea Mayoh, Mark J. Cowley

“…Abstract Background Human Leukocyte Antigens (HLA) play central roles in histocompatibility and immune system functions, including antigen presentation. …”
Get full text

Genetic Variants Are Not Rare in ICD Candidates with Dilated Cardiomyopathy: Time for Next-Generation Sequencing? by Alexandra Sousa, Paulo Canedo, Manuel Campelo, Brenda Moura, Sérgio Leite, Márcia Baixia, Adriana Belo, Francisco Rocha-Gonçalves, José Carlos Machado, José Silva-Cardoso, Elisabete Martins, FATIMA Investigators

“…We aimed to assess the diagnostic yield of genetic testing in DCM patients with a class I recommendation for ICD implantation, based on current guidelines. …”
Get full text

Impacts of long-term different fertilization regimes on microbial utilization of straw-derived carbon in greenhouse vegetable soils: insights from its ecophysiological roles and te... by Long Ma, Ruonan Li, Haoan Luan, Jiwei Tang, Liying Wang, Tengfei Guo, Shaowen Huang

Get full text

An ensemble deep learning framework for multi-class LncRNA subcellular localization with innovative encoding strategy by Wenxing Hu, Yan Yue, Ruomei Yan, Lixin Guan, Mengshan Li

“…Despite numerous computational methods developed for this purpose, existing approaches still encounter challenges stemming from the complexity of data representation and the difficulty in capturing nucleotide distribution information within sequences. Results In this study, we propose a novel deep learning-based model, termed MGBLncLoc, which incorporates a unique multi-class encoding technique known as generalized encoding based on the Distribution Density of Multi-Class Nucleotide Groups (MCD-ND). …”
Get full text