Effectiveness of intraoperative peritoneal lavage (IOPL) with saline in patient with intra-abdominal infections: a systematic review and meta-analysis protocol by Wenbo Meng, Nan Yang, Qi Zhou, Jingyi Zhang, Xufei Luo, Yaolong Chen, Kehu Yang, Zijun Wang, Qianling Shi, Xuan Yu, Jianjian Wang, Yanfang Ma, Yangqin Xun, Siya Zhao, Bobo Zheng, Robert Sawyer

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Effect of Mavacamten on Echocardiographic Features in Chinese Patients with Obstructive Hypertrophic Cardiomyopathy: Results from the EXPLORER-CN Study by Zhuang Tian, Xiaoyan Li, Liwen Li, Qing Zhang, Jian’an Wang, Yunqi Shi, Daoquan Peng, Ping Yang, Wei Ma, Fang Wang, Wei Jin, Xiang Cheng, Yu-Mao Chen, Yue Zhong, Yu Chen Barrett, Jing Zheng, Shuyang Zhang

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Amicitia and caritas in the 7th Century: Isidore of Seville and His Sources by Sergey Vorontsov

“…The article suggests that the question of true unity in friendship was central for Isidore: he reconsiders patristic model of grounding amicitia in caritas that was interpreted as both the principle of right behaviour towards the neighbour and a ground of general political and religious unity of gens Gothorum. …”
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Formation of biocenoses in roadside landscapes of Cherkasy Region by Ірина Кравцова, Сергій Сонько, Ольга Василенко, Ігор Гурський, Станіслав Огілько

“…In general, the conducted zoning covers only those sections of highways that directly border agricultural lands. …”
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CARACTERIZACIÓN ESTRUCTURAL DEL BOSQUE PANTANOSO DE MIRTÁCEAS DE LA REGIÓN DE LA ARAUCANÍA, CHILE by Jonathan Urrutia Estrada, Enrique Hauenstein Barra

“…Berg, cuyos promedios de altura y diámetro a la altura del pecho (DAP) generales alcanzan los 11.8 m y 22.1 cm, respectivamente. …”
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Lipid Accumulation Product Is More Related to Insulin Resistance than the Visceral Adiposity Index in the Maracaibo City Population, Venezuela by Valmore Bermúdez, Juan Salazar, Jorge Fuenmayor, Manuel Nava, Ángel Ortega, Pablo Duran, Milagros Rojas, Roberto Añez, Alejandra Rivas-Montenegro, Lissé Angarita, Maricarmen Chacín, Clímaco Cano, Manuel Velasco, Joselyn Rojas

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Reevaluating the therapeutic role of extended lymph node dissection in the era of robot-assisted radical prostatectomy by Atsuro Sawada, Koshiro Nishimoto, Shusuke Akamatsu, Masashi Kubota, Takayuki Sumiyoshi, Ryoichi Saito, Ryoma Kurahashi, Yuya Sekine, Hiromitsu Negoro, Yusuke Shiraishi, Ryo Iguchi, Masakazu Nakashima, Kazuki Kokura, Hiroshi Iwamura, Naoki Kohei, Kimihiro Shimatani, Toshiyuki Kamoto, Takashi Kobayashi, Takayuki Goto, Daimonji Clinical Application Database (Dai-CAD) study group

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Association of altitude and eosinophil with the one-year mortality of acute exacerbation of chronic obstructive pulmonary disease: a cohort study by Junqing Li, Zhangchun He, Chengyue Zhu, Rongrong Li, Zixuan Zheng, Hanwei Zhao, Yue Dong, Zhijun Jie, Heyuan Ding, Jindong Shi

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Unintended consequences: quantifying the benefits, iatrogenic harms and downstream cascade costs of musculoskeletal MRI in UK primary care by Imran Mohammed Sajid, Kathleen Frost, Anand Parkunan

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Examining the Effects of Construction Project Delays on Costs from the Perspective of Stakeholders Using a System Dynamics Approach: Insights from a Commercial Complex Project in Q... by Amirhosein Saffarinia, Hamidreza Yazdani

“…Consequently, delays are generally a costly problem. In some cases, it has been observed that delays may not be costly for all parties involved and can create conflicts of interest. …”
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Ex-President of Botswana Ian Khama: Ascents and Reversals in the Political Career of a Former Pilot by PROKOPENKO Liubov Yaroslavovna

“…The properties of the situation in the Botswana Democratic Party, which has ruled the country for almost 55 years and still holds a central position in the country’s political landscape, are shown. …”
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Nomogram for predicting the risk of cervical lymph node metastases and recurrence in papillary thyroid carcinoma based on the thyroid differentiation score system and clinical char... by Yutong Liu, Xuanjie Wang, Xiaodan Sun, Hongxue Li, Lidong Wang

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The Role of PLIN3 in Prognosis and Tumor-Associated Macrophage Infiltration: A Pan-Cancer Analysis by Yang S, Liu H, Zheng Y, Chu H, Lu Z, Yuan J, Xu S

“…Shaohua Yang,1– 3,* Hejie Liu,4,* Youbin Zheng,5,* Hongyu Chu,6 Zhuming Lu,4 Jie Yuan,1,2 Shengshan Xu4 1Department of General Surgery, Foshan Clinical Medical School, Guangzhou University of Chinese Medicine, Foshan, Guangdong, People’s Republic of China; 2Department of General Surgery, Foshan Fosun Chancheng Hospital, Foshan, Guangdong, People’s Republic of China; 3Institute of Gastroenterology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People’s Republic of China; 4Department of Thoracic Surgery, Jiangmen Central Hospital, Jiangmen, Guangdong, People’s Republic of China; 5Department of Radiology, Jiangmen Wuyi Hospital of Traditional Chinese Medicine, Jiangmen, Guangdong, People’s Republic of China; 6Department of Gastrointestinal, Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Yuan, Email yuanj1282024@163.com Shengshan Xu, Email xushengshan97@163.comBackground: Nucleolar and spindle-associated protein 1 (PLIN3), a member of the perilipin family, plays a critical role in lipid droplet dynamics and is implicated in promoting tumor progression across several cancers. …”
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Outbreaks of COVID-19 in Medical organizations by Y. I. Sisin, A. A. Golubkova, I. I. Kozlova, N. A. Ostapenko

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Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4-Mediated Microtubule Destabilization by Sun Z, Liu J, Ge P, Cao Y, Liu J, Wen H, Luo X, Pei B, Jin Z, Li H, Xun L, Luo Y, Yang Q, Chen H

“…Zhenxuan Sun,1– 3,* Jie Liu,1– 3,* Peng Ge,1– 3,* Yinan Cao,4 Jin Liu,1– 3 Haiyun Wen,1– 3 Xinyu Luo,1– 3 Boliang Pei,1– 3 Zuocang Jin,1,3 Huijuan Li,3 Lu Xun,1– 3 Yalan Luo,5 Qi Yang,6 Hailong Chen1– 3 1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 2Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 3Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 4Day Surgery Center, Dalian Municipal Central Hospital, Dalian, Liaoning, 116033, People’s Republic of China; 5Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Chen, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Zhongshan Road 222, Dalian, Liaoning, 116011, People’s Republic of China, Tel +86 411 83635963, Fax +86 411 83622844, Email chenhailong@dmu.edu.cnPurpose: Explore the therapeutic effect and molecular mechanism of rhein on severe acute pancreatitis associated acute lung injury (SAP-ALI).Methods: The SAP-ALI rat model was constructed by retrograde injection of 5% sodium taurocholate into the pancreaticobiliary duct, and pulmonary microvascular endothelial cell (PMVEC) injury model was induced by LPS. …”
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Research on the Pattern Evolution of Innovation Output Space in Guangzhou Metropolitan Area Based on Authorized Invention Patent Data by Shan Zhuoran, Liu Sisi, Yuan Man, Zhu Junqing

“…The results show that: (1) the evolution of innovation output space generally follows the pattern of "gathering in the core area of the main district of the central city in a metropolitan region, generating innovation output growth points in the secondary cities and forming a number of innovation output cross-border integration areas." (2) The innovation output space of enterprises continues to cluster toward industrial parks and technology parks with clear boundaries, and the extensive construction of parks has driven the decentralized development of innovation output space of enterprises; The innovation output space of scientific research institutions, with strong stability, has always been highly concentrated in the core area of the main city of Guangzhou and has expanded with the construction of university towns within the metropolitan area; The individual innovation output has shifted from "explosive spatial dispersion" to "organized spatial convergence", and the adsorption effect of urban rail transit on individual innovation output is becoming increasingly significant. (3) The three types of innovation outputs always have spatial proximity characteristics, and enterprise innovation is the main driving force for innovation diffusion in the periphery of metropolitan areas. (4) Regional innovation output is influenced by both the innovation environment and innovation inputs, among which government support is the most critical driving force affecting the three types of innovation outputs. …”
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Lesões neurológicas na blastomicose sul-americana estudo anatomopatológico de 14 casos by Walter C. Pereira, Açucena Raphael, Jamil Sallum

“…The Paracoccidioides brasiliensis are generally abundantly found either free or phagocyted by histiocytes or gigantocytes. …”
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Early Detection of Malignant Cells in Gastric Lavage via Hexokinase 2 and Single-Cell Sequencing for Gastric Cancer Diagnosis by Qian P, Sun J, Zhao Z, Lu P

“…Peiyu Qian,1,2,* Jie Sun,3,* Zhenya Zhao,4 Peihua Lu5 1Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, People’s Republic of China; 2Minhang Fudan Medical Education Research Center, Minhang District Central Hospital, Fudan University, Shanghai, 201100, People’s Republic of China; 3Center of Clinical Research, the Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi, 214023, People’s Republic of China; 4International Medical Care Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of China; 5Department of Oncology, the Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi, 214023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Peihua Lu, Department of Oncology, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi, 214023, People’s Republic of China, Tel +8613918164127, Email lphty1_1@163.com Zhenya Zhao, International medical care Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of China, Tel +8615221091968, Email 15221091968@163.comObjective: Gastric cancer represents a significant global health challenge due to its high prevalence and mortality rates, largely attributed to the limitations of current screening methods, such as endoscopy, which impede early diagnosis. …”
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Tumor-Infiltrating Immune Cells and PD-L1 as Prognostic Biomarkers in Primary Esophageal Small Cell Carcinoma by Xiao Wu, Xiurong Ke, Yangpeng Ni, Liping Kuang, Fan Zhang, Yusheng Lin, Wan Lin, Xiao Xiong, Haihua Huang, Xianjie Lin, Hao Zhang

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Las Eritrodermias by Juan Guillermo Chalela

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